[go: up one dir, main page]

MY109719A - Long-acting biodegradable microparticles and a process for their preparation. - Google Patents

Long-acting biodegradable microparticles and a process for their preparation.

Info

Publication number
MY109719A
MY109719A MYPI92000482A MYPI19920482A MY109719A MY 109719 A MY109719 A MY 109719A MY PI92000482 A MYPI92000482 A MY PI92000482A MY PI19920482 A MYPI19920482 A MY PI19920482A MY 109719 A MY109719 A MY 109719A
Authority
MY
Malaysia
Prior art keywords
long
preparation
biodegradable microparticles
acting
acting biodegradable
Prior art date
Application number
MYPI92000482A
Inventor
Jurgen Sandow Dr
Norbert Lill Dr
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of MY109719A publication Critical patent/MY109719A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

LONG-ACTING BIODEGRADABLE MICROPARTICLES CONTAINING THERAPEUTICALLY ACTIVE PEPTIDES AS THE ACTIVE SUBSTANCE AND POLY (LACTIDE-CO-GLYCOLIDE) AS THE CARRIER MATERIAL ARE DESCRIBED WHICH ARE OBTAINED BY SPRAY DRYING AT TEMPERATURES BELOW 60?C AT A SPRAY FLOW RATE OF ABOVE 500 NL/H.
MYPI92000482A 1991-03-25 1992-03-23 Long-acting biodegradable microparticles and a process for their preparation. MY109719A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4109746 1991-03-25

Publications (1)

Publication Number Publication Date
MY109719A true MY109719A (en) 1997-05-31

Family

ID=6428150

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI92000482A MY109719A (en) 1991-03-25 1992-03-23 Long-acting biodegradable microparticles and a process for their preparation.

Country Status (20)

Country Link
EP (1) EP0505966B1 (en)
JP (1) JP3346789B2 (en)
KR (1) KR100203253B1 (en)
AT (1) ATE124254T1 (en)
AU (1) AU653210B2 (en)
CA (1) CA2063883C (en)
CY (1) CY2032A (en)
CZ (1) CZ284756B6 (en)
DE (1) DE59202649D1 (en)
DK (1) DK0505966T3 (en)
ES (1) ES2076592T3 (en)
FI (1) FI99084C (en)
HR (1) HRP940838B1 (en)
IE (1) IE67555B1 (en)
IL (1) IL101346A0 (en)
MY (1) MY109719A (en)
NO (1) NO302856B1 (en)
NZ (1) NZ242073A (en)
YU (1) YU48420B (en)
ZA (1) ZA922130B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100259989B1 (en) * 1991-10-01 2000-08-01 모리다 가쓰라 Sustained release microcapsules formulation and preparation method thereof
JP2651320B2 (en) * 1992-07-16 1997-09-10 田辺製薬株式会社 Method for producing sustained-release microsphere preparation
AU4198793A (en) * 1992-07-24 1994-01-27 Takeda Chemical Industries Ltd. Microparticle preparation and production thereof
WO1994009898A1 (en) * 1992-10-26 1994-05-11 Schwarz Pharma Ag Method of manufacturing microcapsules
GB9423419D0 (en) * 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
CA2192773C (en) 1995-12-15 2008-09-23 Hiroaki Okada Production of sustained-release preparation for injection
CA2192782C (en) * 1995-12-15 2008-10-14 Nobuyuki Takechi Production of microspheres
KR100321854B1 (en) * 1998-12-30 2002-08-28 동국제약 주식회사 Long-term sustained-release microspheres containing luteinizing hormone releasing hormone homologues and a method of producing the same
EP1389467B1 (en) 2001-05-23 2013-07-03 Mitsubishi Tanabe Pharma Corporation Therapeutic composition for the regenerative treatment of cartilage diseases
WO2002094321A1 (en) 2001-05-23 2002-11-28 Tanabe Seiyaku Co., Ltd. Compositions for promoting healing of bone fracture
CA2490351C (en) 2002-06-25 2011-11-01 Takeda Pharmaceutical Company Limited Process for producing sustained-release composition
WO2005092301A1 (en) * 2004-03-26 2005-10-06 Universita' Degli Studi Di Parma Insulin highly respirable microparticles
KR100722607B1 (en) 2006-05-11 2007-05-28 주식회사 펩트론 Method for producing sustained-release microspheres with improved dispersibility and injection dose
FR2934856B1 (en) * 2008-08-05 2010-08-13 Servier Lab NEW PROCESS FOR OBTAINING THE V-CRYSTALLINE FORM OF AGOMELATIN
BR102012011209A2 (en) * 2012-05-11 2014-03-25 Bioactive Biomateriais Ltda BIODEGRADABLE THREE-DIMENSIONAL MATERIAL AND BIODEGRADABLE THREE-DIMENSIONAL MATERIAL PREPARATION PROCESS
CN105963257B (en) * 2016-04-26 2021-01-22 广州帝奇医药技术有限公司 Preparation method of sustained-release particles
CN105963258B (en) * 2016-04-26 2021-01-22 广州帝奇医药技术有限公司 A kind of preparation method of slow-release microparticles
CN109985585A (en) * 2019-05-13 2019-07-09 苏州岸谷纳米技术有限公司 A kind of fast preparation method of Biodegradable high molecular microballoon

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962091A (en) * 1986-05-23 1990-10-09 Syntex (U.S.A.) Inc. Controlled release of macromolecular polypeptides
DE3784594T2 (en) * 1986-08-11 1994-01-05 Innovata Biomed Ltd Pharmaceutical compositions containing microcapsules.
DE3710175A1 (en) * 1987-02-12 1988-08-25 Hoechst Ag MULTI-PIECE IMPLANTABLE MEDICINE PREPARATION WITH LONG-TERM EFFECT
GB2209937B (en) * 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
DE3738228A1 (en) * 1987-11-11 1989-05-24 Hoechst Ag METHOD FOR PRODUCING BIODEGRADABLE MICRO-CAPSULES OF WATER-SOLUBLE PEPTIDES AND PROTEINS AND MICRO-CAPSULES OBTAINED BY THIS PROCESS
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier

Also Published As

Publication number Publication date
HRP940838B1 (en) 2000-12-31
KR100203253B1 (en) 1999-06-15
AU1310992A (en) 1992-10-01
CA2063883C (en) 2001-12-11
IL101346A0 (en) 1992-11-15
ES2076592T3 (en) 1995-11-01
FI921248L (en) 1992-09-26
NZ242073A (en) 1993-08-26
ZA922130B (en) 1992-11-25
EP0505966B1 (en) 1995-06-28
JPH0570363A (en) 1993-03-23
FI921248A0 (en) 1992-03-23
FI99084B (en) 1997-06-30
KR920017645A (en) 1992-10-21
AU653210B2 (en) 1994-09-22
CA2063883A1 (en) 1992-09-26
NO302856B1 (en) 1998-05-04
EP0505966A1 (en) 1992-09-30
IE67555B1 (en) 1996-04-17
YU26392A (en) 1994-12-28
CS88792A3 (en) 1992-10-14
CZ284756B6 (en) 1999-02-17
ATE124254T1 (en) 1995-07-15
NO921147L (en) 1992-09-28
HRP940838A2 (en) 1997-06-30
JP3346789B2 (en) 2002-11-18
DK0505966T3 (en) 1995-10-30
YU48420B (en) 1998-07-10
DE59202649D1 (en) 1995-08-03
NO921147D0 (en) 1992-03-24
IE920956A1 (en) 1992-10-07
FI99084C (en) 1997-10-10
CY2032A (en) 1998-02-20

Similar Documents

Publication Publication Date Title
MY109719A (en) Long-acting biodegradable microparticles and a process for their preparation.
FI930672A7 (en) Method for preparing polymer microcapsules containing biologically active material
FI912639A0 (en) Process for the preparation of active and uniformly sized carrier particles for polymerization catalysts
FI101676B1 (en) Improved process for producing a stable microsphere composition
DE2964530D1 (en) 2,3,4,5-tetrahydro-1h-3-benzazepines, process for their production and pharmaceutical compositions having dopamine receptor blocking activity
ZA934037B (en) Novel biologically active eburnamenine derivatives, pharmaceutical compositions containing them and process for preparing same.
EP0603865A3 (en) Process for the production of alanine.
EP0274053A3 (en) Process for preparing polymer powders by spray drying
FI103727B1 (en) Process for the preparation of therapeutically useful 2-amino-4-substituted-phenyl-4H-pyrano [3,2-h] quinoline-3-carbonitriles
FR2512442B1 (en) CYCLOPENTADIENE DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITION CONTAINING THEM, AND METHOD FOR MANUFACTURING MOLDED ARTICLES USING THE SAME
FI98459B (en) Process for Preparing Therapeutically Useful 5-Ethano-2,3,4,5-1H-2-Bentsazsepine
ZA919984B (en) Salinomycin biomass granules which are free-flowing and dust-free and have unrestricted bioavailability of active substance,and a process for the production thereof
HU913518D0 (en) Substituted aminoacid-amide-derivatives and process for the production of the compounds, and the pesticides containing them
EP0630933A3 (en) Process for the preparation of a semiconductor material.
FR2619676B3 (en) SPRAYER, ESPECIALLY FOR AGRICULTURE
NO176180C (en) Analogous Process for the Preparation of New Therapeutically Active 2-Carbonyl-substituted N, N-di (trimethoxybenzoyl) piperanzines
JPS5282715A (en) Long acting drug composition
JPS5355492A (en) Pellet-like catalyst
FR2689502B1 (en) Process for the production of stabilized 1, 1-dichloro-1-fluorethane ("141b") and product obtained.
HUT42918A (en) Insecticides and acaricides containing as active substance derivatives of 1,3,5-oxadiazin-2-on and process for production of the active substance
IT1203299B (en) PROCEDURE AND DEVICE FOR THE PREPARATION OF A BASIC MATERIAL FOR THE PRODUCTION OF A BIOLOGICALLY ACTIVE PREPARATION, SUCH AS PEPSINE OR MUCINA, FROM THE STOMACH OF PIGS
EP0632086A3 (en) Process for the preparation of a semiconductor material.
HUT63655A (en) New vector for the production of biologically important peptides
HUT68138A (en) Neu method for indentifying of biologically active peptides from mixtures of peptides, by cell-binding researches
IT218061Z2 (en) SPRAY NOZZLE SUPPORT FOR AGRICULTURAL APPLICATION