[go: up one dir, main page]

MXPA06007511A - Drug granule coatings that impart smear resistance during mechanical compression. - Google Patents

Drug granule coatings that impart smear resistance during mechanical compression.

Info

Publication number
MXPA06007511A
MXPA06007511A MXPA06007511A MXPA06007511A MXPA06007511A MX PA06007511 A MXPA06007511 A MX PA06007511A MX PA06007511 A MXPA06007511 A MX PA06007511A MX PA06007511 A MXPA06007511 A MX PA06007511A MX PA06007511 A MXPA06007511 A MX PA06007511A
Authority
MX
Mexico
Prior art keywords
disclosed
substrate
mechanical compression
coating
granule
Prior art date
Application number
MXPA06007511A
Other languages
Spanish (es)
Inventor
Noymi Yam
David Edgren
Alya Khan
Abdul Majid Qureshi
James Ergun
Satishkumar Ramachandran
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of MXPA06007511A publication Critical patent/MXPA06007511A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A drug formulation is disclosed comprising granules having a substrate and a coating, said granule substrate comprising a solubilizing surfactant or a low solubility therapeutic drug, or both, and said granule coating comprising a hydrophilic polymer. Also disclosed is a drug formulation consisting of a tablet core made by mechanical compression, wherein said tablet core comprises granules having a substrate and a coating, said granule substrate comprising a solubilizing surfactant or a low solubility therapeutic drug, or both, and said granule coating comprising a hydrophilic polymer. Also disclosed is a dosage form for oral administration of topiramate, comprising a tablet core and an osmotic delivery system. Methods for controlling topiramate release patterns by altering the composition of the topiramate dosage form are also disclosed.
MXPA06007511A 2003-12-29 2004-12-28 Drug granule coatings that impart smear resistance during mechanical compression. MXPA06007511A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53347003P 2003-12-29 2003-12-29
US53311203P 2003-12-29 2003-12-29
PCT/US2004/043931 WO2005065647A2 (en) 2003-12-29 2004-12-28 Drug granule coatings that impart smear resistance during mechanical compression

Publications (1)

Publication Number Publication Date
MXPA06007511A true MXPA06007511A (en) 2009-06-10

Family

ID=34752987

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA06007511A MXPA06007511A (en) 2003-12-29 2004-12-28 Drug granule coatings that impart smear resistance during mechanical compression.

Country Status (6)

Country Link
EP (1) EP1701707A2 (en)
JP (1) JP2007517062A (en)
AU (1) AU2004312083A1 (en)
CA (1) CA2551825A1 (en)
MX (1) MXPA06007511A (en)
WO (1) WO2005065647A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007169273A (en) * 2005-11-28 2007-07-05 Takeda Chem Ind Ltd Medicinal preparation of which attachment to pestle is improved
JP5527921B2 (en) * 2006-12-22 2014-06-25 エスエス製薬株式会社 Oral solid composition concealing bitterness
DE102012014848A1 (en) * 2012-07-27 2012-10-31 Heilerde-Gesellschaft Luvos Just GmbH & Co. KG Healing clay-composition present as non-coated or as coated granules, comprises healing clay and binding agent containing at least one water soluble polymer e.g. starch, tragacanth or cellulose acetate, cellulose ether
CA2906172C (en) * 2013-03-15 2021-12-21 Aprecia Pharmaceuticals Company Rapidly dispersible dosage form of topiramate
US20220211688A1 (en) 2019-04-25 2022-07-07 Fuji Pharma Co., Ltd. Pharmaceutical preparation and method for producing the same
WO2022091442A1 (en) 2020-10-28 2022-05-05 株式会社キノファーマ Pharmaceutical composition for preventing or treating viral perivaginal disease
WO2024225348A1 (en) * 2023-04-27 2024-10-31 住友精化株式会社 Granulated material and method for producing same, granulated composition, and composition for preparations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA65607C2 (en) * 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Pharmaceutical composition (variants) and process for its preparation
AU2003225102A1 (en) * 2002-04-23 2003-11-10 Bristol-Myers Squibb Company Modified-release vasopeptidase inhibitor formulation, combinations and method
AR039744A1 (en) * 2002-06-26 2005-03-09 Alza Corp METHODS AND DOSAGE FORMS TO INCREASE THE SOLUBILITY OF PHARMACOS COMPOSITIONS FOR CONTROLLED ADMINISTRATION
EP1534238A1 (en) * 2002-07-29 2005-06-01 ALZA Corporation Formulations and dosage forms for controlled delivery of topiramate
CA2534920A1 (en) * 2003-08-06 2005-02-24 Alza Corporation Uniform delivery of topiramate over prolonged period of time with enhanced dispersion formulation
WO2005020959A2 (en) * 2003-09-02 2005-03-10 Alza Corporation Novel drug compositions and dosage forms of topiramate
KR20060123493A (en) * 2003-12-23 2006-12-01 알자 코포레이션 Methods and formulations for increasing solubility of drug compositions for controlled delivery

Also Published As

Publication number Publication date
EP1701707A2 (en) 2006-09-20
WO2005065647A3 (en) 2005-12-08
CA2551825A1 (en) 2005-07-21
WO2005065647A2 (en) 2005-07-21
JP2007517062A (en) 2007-06-28
AU2004312083A1 (en) 2005-07-21

Similar Documents

Publication Publication Date Title
CA2446712C (en) System for osmotic delivery of pharmaceutically active agents
WO2007000778A3 (en) Modified release pharmaceutical compositions on the basis of two polymers and processes thereof
MXPA03012041A (en) Gastric retention controlled drug delivery system.
WO2003028660A3 (en) Drug delivery devices and methods
EP1945197A1 (en) Stabilized extended release pharmaceutical compositions comprising a beta-adrenoreceptor antagonist
WO2002053100A3 (en) Pharmaceutical dosage form for oral administration of low molecular weight heparin
BR0103033A (en) Pharmaceutical particles of masked flavor
KR20130086128A (en) Easily dosable solid preparation
HRP20100372T1 (en) Pharmaceutical compositions of a neuroactive steroid and uses thereof
WO2007054976A3 (en) Lipid based controlled release pharmaceutical composition
WO2005009357A3 (en) Controlled release compositions
AU2001291526A1 (en) Sustained release composition containing clarithromycin
EP1460998B1 (en) Extended release pharmaceutical tablet of metformin
MY130332A (en) Pharmaceutical formulation comprising iota-carrageenan and at least one neutral gelling polymer
WO2005117843A3 (en) Sustained release preparations
PL1638535T3 (en) Subcutaneous implants having limited initial release of the active principle and subsequent linearly varying extended release thereof
WO2003074033A8 (en) Sustained/controlled release solid formulation as a novel drug delivery system with reduced risk of dose dumping
WO2005007074A3 (en) Gellan gum based oral controlled release dosage forms- a novel platform technology for gastric retention
MXPA06007511A (en) Drug granule coatings that impart smear resistance during mechanical compression.
CA2417887A1 (en) Particulate composition of eletriptan
CN101141962B (en) Tablet-type controlled-release preparation for combating vertigo
WO2004078111A3 (en) Extended release minocycline compositions and processes for their preparation
WO2005013935A3 (en) Composition for releasing a weak base for an extended period of time
RS20050835A (en) Compositions of buccal dosage forms for extended drug release and the process of preparing such compositions
KR100920856B1 (en) Prolonged-release preparations of selective serotonin reuptake inhibitors and preparation methods thereof