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MXPA05011679A - Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents. - Google Patents

Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents.

Info

Publication number
MXPA05011679A
MXPA05011679A MXPA05011679A MXPA05011679A MXPA05011679A MX PA05011679 A MXPA05011679 A MX PA05011679A MX PA05011679 A MXPA05011679 A MX PA05011679A MX PA05011679 A MXPA05011679 A MX PA05011679A MX PA05011679 A MXPA05011679 A MX PA05011679A
Authority
MX
Mexico
Prior art keywords
biphenyl
hydroxy
oxime derivatives
carbaldehyde oxime
estrogenic agents
Prior art date
Application number
MXPA05011679A
Other languages
Spanish (es)
Inventor
Cijiang Yang
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MXPA05011679A publication Critical patent/MXPA05011679A/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/48—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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Abstract

This invention provides estrogen receptor modulators having the structure formula (I): wherein R1 to R6 and R8 are as defined in the specification; or a pharmaceutically acceptable salt thereof.
MXPA05011679A 2003-05-02 2004-04-30 Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents. MXPA05011679A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46739403P 2003-05-02 2003-05-02
US10/835,228 US7279600B2 (en) 2003-05-02 2004-04-29 Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents
PCT/US2004/013316 WO2004099122A2 (en) 2003-05-02 2004-04-30 Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents

Publications (1)

Publication Number Publication Date
MXPA05011679A true MXPA05011679A (en) 2006-01-23

Family

ID=33436730

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05011679A MXPA05011679A (en) 2003-05-02 2004-04-30 Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents.

Country Status (13)

Country Link
US (2) US7279600B2 (en)
EP (1) EP1620392B1 (en)
JP (1) JP2006525346A (en)
AT (1) ATE365708T1 (en)
AU (1) AU2004236213A1 (en)
BR (1) BRPI0409960A (en)
CA (1) CA2523712A1 (en)
DE (1) DE602004007257T2 (en)
DK (1) DK1620392T3 (en)
ES (1) ES2289538T3 (en)
MX (1) MXPA05011679A (en)
PL (1) PL1620392T3 (en)
WO (1) WO2004099122A2 (en)

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US7279600B2 (en) 2007-10-09
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