MXPA04010589A - Polimero sensible a ph. - Google Patents
Polimero sensible a ph.Info
- Publication number
- MXPA04010589A MXPA04010589A MXPA04010589A MXPA04010589A MXPA04010589A MX PA04010589 A MXPA04010589 A MX PA04010589A MX PA04010589 A MXPA04010589 A MX PA04010589A MX PA04010589 A MXPA04010589 A MX PA04010589A MX PA04010589 A MXPA04010589 A MX PA04010589A
- Authority
- MX
- Mexico
- Prior art keywords
- sensitive polymer
- haemolysis
- meth
- weight
- units
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
La invencion trata de un polimero sensible a pH que es un copolimero de metacrilato compuesto de 20 a 65% por peso de unidades de acido acrilico y/o metacrilico y 80 a 35% por peso de unidades de esteres de alquilo de 1 a 18 atomos de carbono de acido metacrilico, que se caracteriza en que tiene un peso molecular en el margen de 1,000 a 50,000 g/mol, y ocasiona por lo menos 60% de la hemolisis en pH 5.5, y menos de 5% de hemolisis en pH 7.4, en una concentracion de 150 °g/ml en una prueba de citotoxicidad con globulos rojos humanos. La invencion trata ademas del uso del polimero sensible a pH como un portador para biomoleculas farmaceuticamente efectivas o ingredientes farmaceuticos activos y como ingrediente de las formas de dosificacion correspondientes.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1999/000122 WO1999034831A1 (en) | 1998-01-05 | 1999-01-05 | Enhanced transport using membrane disruptive agents |
| DE10219505 | 2002-04-30 | ||
| DE10220470A DE10220470A1 (de) | 2002-04-30 | 2002-05-07 | ph-sensitives Polymer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04010589A true MXPA04010589A (es) | 2005-12-05 |
Family
ID=29264970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04010589A MXPA04010589A (es) | 1999-01-05 | 1999-01-05 | Polimero sensible a ph. |
Country Status (1)
| Country | Link |
|---|---|
| MX (1) | MXPA04010589A (es) |
-
1999
- 1999-01-05 MX MXPA04010589A patent/MXPA04010589A/es active IP Right Grant
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| HC | Change of company name or juridical status |