[go: up one dir, main page]

MXPA03011538A - Composicion medicinal que sustancialmente no causaria dano a la mucosa intestinal. - Google Patents

Composicion medicinal que sustancialmente no causaria dano a la mucosa intestinal.

Info

Publication number
MXPA03011538A
MXPA03011538A MXPA03011538A MXPA03011538A MXPA03011538A MX PA03011538 A MXPA03011538 A MX PA03011538A MX PA03011538 A MXPA03011538 A MX PA03011538A MX PA03011538 A MXPA03011538 A MX PA03011538A MX PA03011538 A MXPA03011538 A MX PA03011538A
Authority
MX
Mexico
Prior art keywords
sorbefacient
drug
active substance
pharmacologically active
medicinal compositions
Prior art date
Application number
MXPA03011538A
Other languages
English (en)
Inventor
Kimura Toshikiro
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of MXPA03011538A publication Critical patent/MXPA03011538A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invencion proporciona una composicion medicinal que comprende (1) una sustancia farmacologicamente activa, (2) un factor de absorcion del farmaco (3) un compuesto de taurina o una poliamina; un compuesto de taurina tiene un efecto de suprimir o evitar el dano de una membrana mucosa intestinal, y por lo tanto agregar el compuesto de taurina a una composicion medicinal que contiene una sustancia farmacologicamente activa y un factor de absorcion del farmaco que hacen posible suprimir o evitar el dano de la mucosa intestinal; una poliamina mejora la capacidad de absorbencia de las sustancias farmacologicamente activas y por lo tanto agrega la poliamina a una composicion medicinal que contiene una sustancia farmacologicamente activa y un factor de absorcion del farmaco que hace posible disminuir la dosis del factor de absorcion del farmaco, por lo tanto suprime o evita el dano de la mucosa intestinal.
MXPA03011538A 2001-06-14 2002-06-14 Composicion medicinal que sustancialmente no causaria dano a la mucosa intestinal. MXPA03011538A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001180373 2001-06-14
JP2001298839 2001-09-28
PCT/JP2002/005954 WO2002102414A1 (fr) 2001-06-14 2002-06-14 Compositions medicinales

Publications (1)

Publication Number Publication Date
MXPA03011538A true MXPA03011538A (es) 2004-03-09

Family

ID=26616910

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03011538A MXPA03011538A (es) 2001-06-14 2002-06-14 Composicion medicinal que sustancialmente no causaria dano a la mucosa intestinal.

Country Status (9)

Country Link
US (3) US6884768B2 (es)
EP (2) EP2591806A1 (es)
KR (3) KR100994221B1 (es)
CN (2) CN100350977C (es)
AU (1) AU2002313236B2 (es)
CA (2) CA2662967C (es)
MX (1) MXPA03011538A (es)
TW (1) TWI239247B (es)
WO (1) WO2002102414A1 (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE44578E1 (en) 2000-04-10 2013-11-05 Teva Pharmaceutical Industries, Ltd. Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids
US20050032811A1 (en) 2003-08-06 2005-02-10 Josiah Brown Methods for administering aripiprazole
WO2005023225A1 (en) * 2003-09-05 2005-03-17 Ranbaxy Laboratories Limited Cilostazol adsorbate
PL1675573T4 (pl) 2003-10-23 2016-04-29 Otsuka Pharma Co Ltd Sterylny preparat do wstrzykiwań arypiprazolu o kontrolowanym uwalnianiu i sposób
EP3424508B1 (en) * 2004-05-19 2021-05-05 Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center Use of sodium deoxycholate for the removal of localized fat accumulation
US7754230B2 (en) * 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
US20060127468A1 (en) * 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
US20090047347A1 (en) * 2005-07-29 2009-02-19 Aegis Therapeutics, Inc. Compositions for Drug Administration
US20110257096A1 (en) * 2004-08-25 2011-10-20 Aegis Therapeutics, Inc. Compositions for drug administration
US20140162965A1 (en) 2004-08-25 2014-06-12 Aegis Therapeutics, Inc. Compositions for oral drug administration
US20060046962A1 (en) 2004-08-25 2006-03-02 Aegis Therapeutics Llc Absorption enhancers for drug administration
US9114069B2 (en) * 2004-08-25 2015-08-25 Aegis Therapeutics, Llc Antibacterial compositions for drug administration
WO2006030301A1 (en) * 2004-09-17 2006-03-23 Ranbaxy Laboratories Limited Cilostazol- containing pharmaceutical composition based on particles of less than 50 micrometers
TWI363626B (en) * 2004-11-15 2012-05-11 Otsuka Pharma Co Ltd Aqueous ophthalmic suspension of crystalline rebamipide
EP1933814A2 (en) * 2005-09-15 2008-06-25 Elan Pharma International Limited Nanoparticulate aripiprazole formulations
US8920918B2 (en) * 2005-10-31 2014-12-30 Kee Action Sports Technology Holdings, Llc Oil and polyethylene glycol fill material for use in paintball shells
TW200808375A (en) * 2006-05-12 2008-02-16 Otsuka Pharma Co Ltd Hydrogel suspension and manufacturing process thereof
US8226949B2 (en) 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
US20080075785A1 (en) * 2006-09-22 2008-03-27 San-Laung Chow Controlled release hydrogel formulation
US20110165236A1 (en) * 2006-09-22 2011-07-07 Biokey, Inc. Controlled release hydrogel formulation
TWI415629B (zh) * 2006-10-26 2013-11-21 Otsuka Pharma Co Ltd 含有瑞巴匹特之水性醫藥懸浮物及其製造方法
EP2011491A1 (en) * 2007-07-05 2009-01-07 Institut National De La Sante Et De La Recherche Medicale (Inserm) Anticonvulsive pharmaceutical compositions
EP2167068A2 (en) * 2007-07-05 2010-03-31 Inserm-Institut National De La Sante Et De La Recherche Medicale Anticonvulsive pharmaceutical compositions
NO2170279T3 (es) 2007-07-31 2018-05-26
ES2406939T3 (es) * 2007-10-19 2013-06-10 Otsuka Pharmaceutical Co., Ltd. Preparación farmacéutica de matriz sólida
CA2756690C (en) 2008-03-28 2016-08-16 Hale Biopharma Ventures, Llc Administration of benzodiazepine compositions
ES2377552T3 (es) 2008-09-17 2012-03-28 Helm Ag Composiciones disueltas fácilmente y estables de candesartán cilexetilo preparadas con una granulación por vía húmeda
US8440631B2 (en) 2008-12-22 2013-05-14 Aegis Therapeutics, Llc Compositions for drug administration
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
EP3406244B1 (en) * 2009-04-15 2023-06-07 BMG Pharma S.p.A. Compositions comprising zinc gluconate and taurine for mucosal or dermal disorders
CN102145003B (zh) * 2010-02-08 2015-04-22 张立英 含难溶性药物的药用组合物
EP2898881B1 (en) * 2010-08-04 2018-10-10 Pierrel Pharma S.R.L. Compositions comprising supramolecular complexes of polyanionic polymers and spermidine for use in the treatment of periodontum and damaged oral tissue
EP2608781A4 (en) * 2010-08-04 2014-01-29 Tixupharma INCLUSION COMPLEXES OF CYCLODEXTRINS WITH SPERMIDINE AND PROLIFERATIVE BZW. REPAIR COMPOSITIONS THEREWITH
KR101277021B1 (ko) * 2010-12-28 2013-06-24 주식회사 드림파마 위체류 약물 전달시스템을 이용한 경구용 방출제어형 레바미피드-함유 이층정 제제 및 그 제조방법
MX363465B (es) 2011-02-18 2019-03-25 Kythera Biopharmaceuticals Inc Tratamiento de la grasa submental.
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
EP4085899A1 (en) 2011-06-14 2022-11-09 Neurelis, Inc. Administration of benzodiazepine
CN102357084B (zh) * 2011-10-11 2014-02-26 广东彼迪药业有限公司 一种马来酸依那普利的片剂组合物及其制备与应用
US10918612B2 (en) * 2013-01-22 2021-02-16 Markus Zwickl Combinations with 2-aminoethanesulfonic acid
US20160136282A1 (en) * 2014-11-18 2016-05-19 Genovate Biotechnology Co., Ltd. Novel formulation of cilostazol, a quinolinone-derivative used for alleviating the symptom of intermittent claudication in patients with peripheral vascular disease
PE20180690A1 (es) 2015-04-27 2018-04-23 Intercept Pharmaceuticals Inc Composiciones de acido obeticolico y metodos de uso

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4591605A (en) 1981-11-10 1986-05-27 Research Foundation Of State University Of New York Method and ingestible formulation for inhibiting the secretion of stomach acid
NZ212053A (en) * 1984-05-17 1988-02-29 Merrell Dow Pharma Polyamine containing pharmaceutical compositions for treating neoplasms
JP2911496B2 (ja) * 1989-09-11 1999-06-23 帝國製薬株式会社 生理活性ポリペプチド含有高吸収性経膣剤
JPH03275633A (ja) * 1990-03-23 1991-12-06 Teikoku Seiyaku Co Ltd 生理活性ポリペプチドの吸収促進剤
US5328844A (en) * 1990-05-09 1994-07-12 University Of Colorado Foundation, Inc. Culture media for mammalian cells
JPH0733667A (ja) * 1992-07-03 1995-02-03 Japan Tobacco Inc ４，６−ｏ−ヒドロキシホスホリルグルコサミン誘導体の水溶液及び水溶化方法
JPH0656643A (ja) * 1992-08-03 1994-03-01 Shiseido Co Ltd 皮膚外用製剤
JPH06192108A (ja) * 1992-12-25 1994-07-12 Kanebo Ltd グルコン酸カルシウム経口液剤
JP3690820B2 (ja) * 1993-02-25 2005-08-31 雪印乳業株式会社 乳児用栄養組成物
SE9404196D0 (sv) * 1994-12-02 1994-12-02 Astra Ab New antithrombotic formulation
JP3297969B2 (ja) * 1994-12-26 2002-07-02 ライオン株式会社 点眼剤
CA2208571A1 (en) * 1995-01-10 1996-07-18 Yuzo Kimura Resin particle, medical material and pharmaceutical preparation containing said resin particle
EP0806947A4 (en) 1995-02-03 1998-10-14 Cosmederm Technologies FORMULATIONS AND METHODS FOR REDUCING SKIN IRRITATION
JPH1025255A (ja) * 1996-07-11 1998-01-27 Taisho Pharmaceut Co Ltd 溶解性の改善された難溶性薬剤
JP3677376B2 (ja) 1996-08-13 2005-07-27 武田薬品工業株式会社 医薬
JPH10262607A (ja) 1997-03-28 1998-10-06 Snow Brand Milk Prod Co Ltd 乳幼児用栄養組成物
JPH1160487A (ja) * 1997-06-09 1999-03-02 Taisho Pharmaceut Co Ltd ビタミンｂ１誘導体配合液剤
JPH1160486A (ja) * 1997-06-09 1999-03-02 Taisho Pharmaceut Co Ltd チアミン類配合液剤
JP4403590B2 (ja) 1997-10-02 2010-01-27 大正製薬株式会社 ビタミンｂ１類配合液剤
JP4390030B2 (ja) * 1997-12-03 2009-12-24 大正製薬株式会社 ミノキシジル配合液剤組成物
JP4790123B2 (ja) * 1998-07-24 2011-10-12 ヨー、セオ、ホン 胆汁酸を有する透明水溶液型製剤の調剤
US6207190B1 (en) * 1998-08-13 2001-03-27 Chronorx, Llc Dosage forms for the treatment of the chronic glaucomas

Also Published As

Publication number Publication date
US6884768B2 (en) 2005-04-26
KR20090019915A (ko) 2009-02-25
US20050095290A1 (en) 2005-05-05
EP2591806A1 (en) 2013-05-15
CA2662967A1 (en) 2002-12-27
TWI239247B (en) 2005-09-11
US20040161407A1 (en) 2004-08-19
CA2449952A1 (en) 2002-12-27
CN1813699B (zh) 2012-04-18
US20050100530A1 (en) 2005-05-12
US7531499B2 (en) 2009-05-12
CA2662967C (en) 2012-04-10
CN1813699A (zh) 2006-08-09
EP1407785A1 (en) 2004-04-14
EP1407785A4 (en) 2009-12-02
KR100943309B1 (ko) 2010-02-23
KR100994221B1 (ko) 2010-11-12
CN1518461A (zh) 2004-08-04
WO2002102414A1 (fr) 2002-12-27
KR20080011249A (ko) 2008-01-31
AU2002313236B2 (en) 2007-07-26
CN100350977C (zh) 2007-11-28
AU2002313236B8 (en) 2003-01-02
US7008920B2 (en) 2006-03-07
KR20040011538A (ko) 2004-02-05
CA2449952C (en) 2010-09-28

Similar Documents

Publication Publication Date Title
MXPA03011538A (es) Composicion medicinal que sustancialmente no causaria dano a la mucosa intestinal.
PL343771A1 (en) N-substituted aminotetralins as ligands for the neuropeptide y y5 receptor useful in the treatment of obesity and other disorders
GEP20053473B (en) High Potency Dihydroergotamine Compositions
IN2015DN01132A (es)
GEP20032967B (en) Indolyl-3-Glyoxylic Acid Derivatives As an Antitumor Agent and Pharmaceutical Composition
ATE293995T1 (de) Pharmazeutische zusammensetzungen, die wirkstoffabsorptionsfördernde verbindungen enthalten
BR0211794A (pt) Composição farmacêutica e método para mascarar o sabor de pelo menos um composto farmaceuticamente ativo de sabor desagradável
YU38802A (sh) Nova kompozicija i njena upotreba
ZA200410109B (en) Oral pharmaceutical forms of liquid drugs having improved bioavailability.
GEP20033131B (en) Azabicycloalkanes as CCR5 Modulators, Pharmaceutical Compositions Containing the Same and Their Use for Treatment and Prevention of Diseases Caused by CCR5 Activity
RU2011138835A (ru) Применение производного рапамицина
PL337794A1 (en) Pharmaceutic agent for oral administration containing an active substance and cyclodextrin
TW200630123A (en) Oral medicinal product with modified release of at least one active principle in multimicrocapsular form
BG66093B1 (bg) Състави с контролирано освобождаване, съдържащи нимесулид
MA29744B1 (fr) Formulations posologiques solides de medicaments presentant une adsorption buccale amelioree
ATE292453T1 (de) Antivirale arznei
WO2002036135A3 (en) Compositions for antitumour treatment containing ecteinascidin 743
IS6970A (is) Lyfjablanda á föstu formi sem felur í sér 4-sýanó-tríflúor-3-(4-flúorfenýlsúlfonýl)-2-hýdroxý-2-metýlprópíón-m-tólúidíð og PVP
DE60102590T2 (de) Darreichungsformen zur behandlung von oralen mykosen
BG105570A (en) Pharmaceutical compositions for modified release insulin sensitiser
BRPI0407438A (pt) Sistema terapêutico compreendendo amoxicilina e ácido clavulânico
BR0114395A (pt) Composição farmacêutica para administração por suprimento via oral
AR034142A1 (es) Una composicion farmaceutica, metodo para fabricar un medicamento en base a dicha composicion y uso de la composicion
BE2016C017I2 (es)
DK0742716T3 (da) Farmaceutisk sammensætning til systemisk transdermal indgivelse med det aktive middel morphin-6-glucuronid

Legal Events

Date Code Title Description
FG Grant or registration