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MXPA03010843A - Uso de derivados con azetidinona en el tratamiento de enfermedad de alzheimer. - Google Patents

Uso de derivados con azetidinona en el tratamiento de enfermedad de alzheimer.

Info

Publication number
MXPA03010843A
MXPA03010843A MXPA03010843A MXPA03010843A MXPA03010843A MX PA03010843 A MXPA03010843 A MX PA03010843A MX PA03010843 A MXPA03010843 A MX PA03010843A MX PA03010843 A MXPA03010843 A MX PA03010843A MX PA03010843 A MXPA03010843 A MX PA03010843A
Authority
MX
Mexico
Prior art keywords
alzheimer
disease
treatment
substituted derivatives
azetidinone
Prior art date
Application number
MXPA03010843A
Other languages
English (en)
Inventor
E Davis Harry
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MXPA03010843A publication Critical patent/MXPA03010843A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describen aqui metodos para prevenir, tratar o mejorar los sintomas de la enfermedad d e Alzheimer, para regular la produccion o niveles de peptidos ¦ amiloides (A¦) y/o para regular la cantidad de isoforma 4 de ApoE en la corriente sanguinea y/o cerebro, que incluyen la etapa de administrar a un sujeto que necesita dicho tratamiento una cantidad eficaz d e una composicion que incluye por lo menos un compuesto representado por las formulas (I-X) aqui descriptas.
MXPA03010843A 2001-05-25 2002-05-22 Uso de derivados con azetidinona en el tratamiento de enfermedad de alzheimer. MXPA03010843A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29365101P 2001-05-25 2001-05-25
US32391101P 2001-09-21 2001-09-21
PCT/US2002/016306 WO2002096415A2 (en) 2001-05-25 2002-05-22 Use of azetidinone substituted derivatives in the treatment of alzheimer's disease

Publications (1)

Publication Number Publication Date
MXPA03010843A true MXPA03010843A (es) 2004-02-17

Family

ID=26968071

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03010843A MXPA03010843A (es) 2001-05-25 2002-05-22 Uso de derivados con azetidinona en el tratamiento de enfermedad de alzheimer.

Country Status (14)

Country Link
US (1) US20030013699A1 (es)
EP (1) EP1392287B8 (es)
JP (1) JP2004532868A (es)
AR (1) AR038956A1 (es)
AT (1) ATE345792T1 (es)
AU (1) AU2002308778A1 (es)
CA (1) CA2447884A1 (es)
CY (1) CY1105922T1 (es)
DE (1) DE60216275T2 (es)
DK (1) DK1392287T3 (es)
ES (1) ES2275007T3 (es)
MX (1) MXPA03010843A (es)
PT (1) PT1392287E (es)
WO (1) WO2002096415A2 (es)

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MXPA05004810A (es) 2002-11-06 2005-07-22 Schering Corp Inhibidores de la absorcion del colesterol para el tratamiento de la desmielinizacion.
WO2004081004A1 (en) 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
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Also Published As

Publication number Publication date
ATE345792T1 (de) 2006-12-15
EP1392287B8 (en) 2007-01-10
US20030013699A1 (en) 2003-01-16
EP1392287B1 (en) 2006-11-22
DE60216275D1 (de) 2007-01-04
JP2004532868A (ja) 2004-10-28
DE60216275T2 (de) 2007-06-21
ES2275007T3 (es) 2007-06-01
WO2002096415A2 (en) 2002-12-05
AU2002308778A1 (en) 2002-12-09
DK1392287T3 (da) 2007-03-19
AR038956A1 (es) 2005-02-02
EP1392287A2 (en) 2004-03-03
PT1392287E (pt) 2007-02-28
CY1105922T1 (el) 2011-04-06
CA2447884A1 (en) 2002-12-05
WO2002096415A3 (en) 2003-01-16

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