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MXPA03004700A - Methods and cells for detecting modulators of rgs proteins. - Google Patents

Methods and cells for detecting modulators of rgs proteins.

Info

Publication number
MXPA03004700A
MXPA03004700A MXPA03004700A MXPA03004700A MXPA03004700A MX PA03004700 A MXPA03004700 A MX PA03004700A MX PA03004700 A MXPA03004700 A MX PA03004700A MX PA03004700 A MXPA03004700 A MX PA03004700A MX PA03004700 A MXPA03004700 A MX PA03004700A
Authority
MX
Mexico
Prior art keywords
cells
methods
rgs proteins
detecting modulators
modulators
Prior art date
Application number
MXPA03004700A
Other languages
Spanish (es)
Inventor
Jian Young Cao
Original Assignee
W Y E T H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by W Y E T H filed Critical W Y E T H
Publication of MXPA03004700A publication Critical patent/MXPA03004700A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/001Vector systems having a special element relevant for transcription controllable enhancer/promoter combination

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MXPA03004700A 2000-12-01 2001-12-03 Methods and cells for detecting modulators of rgs proteins. MXPA03004700A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25014700P 2000-12-01 2000-12-01
PCT/US2001/045105 WO2002050104A2 (en) 2000-12-01 2001-12-03 Methods and cells for detecting modulators of rgs proteins

Publications (1)

Publication Number Publication Date
MXPA03004700A true MXPA03004700A (en) 2003-08-19

Family

ID=22946480

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03004700A MXPA03004700A (en) 2000-12-01 2001-12-03 Methods and cells for detecting modulators of rgs proteins.

Country Status (9)

Country Link
EP (1) EP1339740A2 (en)
JP (1) JP2004520824A (en)
KR (1) KR20030081337A (en)
CN (1) CN1478097A (en)
AU (1) AU2002243255A1 (en)
CA (1) CA2430475A1 (en)
IL (1) IL156199A0 (en)
MX (1) MXPA03004700A (en)
WO (1) WO2002050104A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7846671B2 (en) 2002-01-28 2010-12-07 Bristol-Myers Squibb Company Methods of screening for agents that modulate the interaction of RGS and Gαq and urinary incontinence
KR100968640B1 (en) * 2007-10-06 2010-07-06 재단법인서울대학교산학협력재단 Single Cell Signal Analysis
BR112017016821A2 (en) * 2015-02-06 2018-04-03 Cargill Inc polypeptide, nucleic acid, vector, host cell, fermentation medium, use of polypeptide, feed composition and fermentation method
CN105126079B (en) * 2015-09-29 2019-03-01 武汉大学 G-protein signal transduction regulatory protein 14(RGS14) treating function and application in myocardial hypertrophy
CN105106936B (en) * 2015-09-29 2018-05-15 武汉大学 G-protein signal transduction regulatory protein 10(RGS10)Function and application in myocardial hypertrophy is treated
EP3390637A4 (en) 2015-12-17 2019-05-01 Cargill, Incorporated SUGAR TRANSPORTER-MODIFIED YEAST STRAINS AND METHODS OF PRODUCING BIOLOGICAL PRODUCT
BR112019002238A2 (en) 2016-08-05 2019-05-14 Cargill, Incorporated manipulated polypeptide and cell, and fermentation method.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998013513A2 (en) * 1996-09-24 1998-04-02 Cadus Pharmaceutical Corporation Methods and compositions for identifying receptor effectors
AU3977699A (en) * 1998-05-08 1999-11-29 Cadus Pharmaceutical Corporation Ags proteins and nucleic acid molecules and uses therefor

Also Published As

Publication number Publication date
CA2430475A1 (en) 2002-06-27
AU2002243255A1 (en) 2002-07-01
EP1339740A2 (en) 2003-09-03
WO2002050104A3 (en) 2003-04-10
CN1478097A (en) 2004-02-25
KR20030081337A (en) 2003-10-17
WO2002050104A9 (en) 2002-12-19
JP2004520824A (en) 2004-07-15
IL156199A0 (en) 2003-12-23
WO2002050104A2 (en) 2002-06-27

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