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MXPA03001356A - Nuevos agentes inhibidores de beta-amiloides, procedimientos para su preparacion y su uso como medicamentos. - Google Patents

Nuevos agentes inhibidores de beta-amiloides, procedimientos para su preparacion y su uso como medicamentos.

Info

Publication number
MXPA03001356A
MXPA03001356A MXPA03001356A MXPA03001356A MXPA03001356A MX PA03001356 A MXPA03001356 A MX PA03001356A MX PA03001356 A MXPA03001356 A MX PA03001356A MX PA03001356 A MXPA03001356 A MX PA03001356A MX PA03001356 A MXPA03001356 A MX PA03001356A
Authority
MX
Mexico
Prior art keywords
medicaments
producing
same
novel beta
amyloid inhibitors
Prior art date
Application number
MXPA03001356A
Other languages
English (en)
Inventor
Katja Fechteler
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MXPA03001356A publication Critical patent/MXPA03001356A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

El presente invento se refiere a compuestos de la formula general (I); (ver formula) en la que los radicales A, Het, R1, R2 y R3 pueden tener los significados mencionados en la memoria descriptiva y en las reivindicaciones, a procedimientos para su preparacion asi como a la utilizacion de compuestos de la formula general (I) como medicamentos, en particular como medicamentos con efecto inhibidor de beta-amiloides.
MXPA03001356A 2000-08-16 2001-07-21 Nuevos agentes inhibidores de beta-amiloides, procedimientos para su preparacion y su uso como medicamentos. MXPA03001356A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10040016A DE10040016A1 (de) 2000-08-16 2000-08-16 Neue beta-Amyloid Inhibitoren, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
PCT/EP2001/008456 WO2002014313A2 (de) 2000-08-16 2001-07-21 Neue beta-amyloid inhibitoren, verfahren zu deren herstellung und deren verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
MXPA03001356A true MXPA03001356A (es) 2004-04-05

Family

ID=7652614

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03001356A MXPA03001356A (es) 2000-08-16 2001-07-21 Nuevos agentes inhibidores de beta-amiloides, procedimientos para su preparacion y su uso como medicamentos.

Country Status (9)

Country Link
EP (1) EP1311508B1 (es)
JP (1) JP5031171B2 (es)
AT (1) ATE282615T1 (es)
AU (1) AU2002210425A1 (es)
CA (1) CA2417190C (es)
DE (2) DE10040016A1 (es)
ES (1) ES2232669T3 (es)
MX (1) MXPA03001356A (es)
WO (1) WO2002014313A2 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10246890A1 (de) 2002-10-08 2004-04-22 Grünenthal GmbH Substituierte C-Imidazo[1,2-alpyridin-3-yl-methylamine
JP2007509960A (ja) * 2003-10-28 2007-04-19 セプラコア インコーポレーテッド イミダゾ［１，２−ａ］ピリジン抗不安薬
SE0400440D0 (sv) * 2004-02-25 2004-02-25 Active Biotech Ab Novel Cinnamic Amides
TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
RU2008150377A (ru) * 2006-05-19 2010-06-27 Нихон Меди-Физикс Ко., Лтд. (Jp) Новое соединение, обладающее сродством к амилоиду
TW200811175A (en) * 2006-06-21 2008-03-01 Nihon Mediphysics Co Ltd Novel compound with affinity with amyloid
KR20090025282A (ko) * 2006-06-21 2009-03-10 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
CN101636183B (zh) 2007-02-13 2014-03-19 日本医事物理股份有限公司 放射性诊断显像剂的制备方法
WO2009143156A2 (en) * 2008-05-19 2009-11-26 Sepracor Inc. IMIDAZO[1,2-a]PYRIDINE COMPOUNDS
DK2376490T3 (da) * 2008-12-04 2013-04-15 Proximagen Ltd Imidazopyridinforbindelser
JP2014012641A (ja) * 2010-10-29 2014-01-23 Dainippon Sumitomo Pharma Co Ltd 新規ピリジン誘導体
CA3107548A1 (en) 2018-08-06 2020-02-13 Moexa Pharmaceuticals Limited Smad3 inhibitors
JP2022530474A (ja) * 2019-04-26 2022-06-29 ジェネロス バイオファーマ リミテッド 複素環含有化合物、その使用及びそれを含む組成物
CA3262061A1 (en) * 2022-07-18 2024-01-25 Moexa Pharmaceuticals Limited Substituted Imidazo [1,2-A]Pyridine Compounds and Their Use in the Treatment and Prevention of Fibrosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique
FR2525601A1 (fr) * 1982-04-21 1983-10-28 Synthelabo Derives d'imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
JP2777159B2 (ja) * 1988-12-22 1998-07-16 エーザイ株式会社 環状アミン誘導体を含有する医薬
ES2204932T3 (es) * 1994-09-12 2004-05-01 Eli Lilly And Company Limited Moduladores serotonergicos.
AU2388697A (en) * 1996-04-19 1997-11-12 Neurosearch A/S 1-(4-piperidyl)-benzimidazoles having neurotrophic activity
US5869500A (en) * 1996-12-13 1999-02-09 Hoffmann-La Roche Inc. Pyridone compounds useful in treating Alzheimer's disease
HRP20000523A2 (en) * 1998-03-06 2001-02-28 Janssen Pharmaceutica Nv Glycine transport inhibitors

Also Published As

Publication number Publication date
JP2004506633A (ja) 2004-03-04
CA2417190A1 (en) 2003-01-24
WO2002014313A3 (de) 2002-05-23
CA2417190C (en) 2010-10-26
DE50104557D1 (de) 2004-12-23
EP1311508A2 (de) 2003-05-21
EP1311508B1 (de) 2004-11-17
ES2232669T3 (es) 2005-06-01
DE10040016A1 (de) 2002-02-28
JP5031171B2 (ja) 2012-09-19
WO2002014313A2 (de) 2002-02-21
AU2002210425A1 (en) 2002-02-25
ATE282615T1 (de) 2004-12-15

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Legal Events

Date Code Title Description
HC Change of company name or juridical status
FG Grant or registration