MXPA03000905A - Compuestos de poliamina ciclicos como tratamiento contra el cancer. - Google Patents
Compuestos de poliamina ciclicos como tratamiento contra el cancer.Info
- Publication number
- MXPA03000905A MXPA03000905A MXPA03000905A MXPA03000905A MXPA03000905A MX PA03000905 A MXPA03000905 A MX PA03000905A MX PA03000905 A MXPA03000905 A MX PA03000905A MX PA03000905 A MXPA03000905 A MX PA03000905A MX PA03000905 A MXPA03000905 A MX PA03000905A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer therapy
- polyamine compounds
- cyclic polyamine
- cyclic
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 125000004122 cyclic group Chemical group 0.000 title 1
- 238000011275 oncology therapy Methods 0.000 title 1
- 229920000768 polyamine Polymers 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
- C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22252200P | 2000-08-02 | 2000-08-02 | |
| PCT/US2001/024282 WO2002010142A1 (en) | 2000-08-02 | 2001-08-02 | Cyclic polyamine compounds for cancer therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03000905A true MXPA03000905A (es) | 2003-06-24 |
Family
ID=22832553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03000905A MXPA03000905A (es) | 2000-08-02 | 2001-08-02 | Compuestos de poliamina ciclicos como tratamiento contra el cancer. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1305299A1 (es) |
| JP (1) | JP2004505112A (es) |
| AU (2) | AU2001278143B2 (es) |
| CA (1) | CA2417064A1 (es) |
| IL (1) | IL153864A0 (es) |
| MX (1) | MXPA03000905A (es) |
| WO (1) | WO2002010142A1 (es) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1040993B (en) | 1999-04-30 | 2006-11-10 | Cellgate, Inc. | Polyamines and their use in therapy |
| EP1337504A4 (en) | 2000-11-08 | 2005-10-05 | Cellgate Inc | NOVEL AMINO ACID CONJUGATES AND POLYAMINE ANALOGUES USEFUL AS ANTICANCING AGENTS |
| JP2005533820A (ja) * | 2002-06-26 | 2005-11-10 | セルゲイト， インコーポレイテッド | 癌治療のためのポルフィリン−ポリアミン結合体 |
| BRPI0614805A2 (pt) | 2005-08-10 | 2011-04-12 | Univ Johns Hopkins | poliaminas úteis como produtos terapêuticos antiparasìticos e anticáncer e como inibidores de demetilase lisina-especìficos |
| US9241898B2 (en) | 2008-03-11 | 2016-01-26 | Yale University | Compositions and methods for controlled delivery of inhibitory ribonucleic acids |
| US9822364B2 (en) | 2008-03-11 | 2017-11-21 | Yale University | Compositions and methods for controlled delivery of inhibitory ribonucleic acids |
| US9895451B2 (en) | 2011-12-02 | 2018-02-20 | Yale University | Formulations for targeted release of agents to low pH tissue environments or cellular compartments and methods of use thereof |
| WO2013082529A1 (en) | 2011-12-02 | 2013-06-06 | Yale University | Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery |
| US10465042B2 (en) | 2011-12-02 | 2019-11-05 | Yale University | Poly(amine-co-ester) nanoparticles and methods of use thereof |
| IN2012DE00661A (es) | 2012-03-07 | 2015-08-21 | Univ Delhi | |
| DE112013002530T5 (de) * | 2012-05-15 | 2015-02-19 | Thermo Electron Scientific Instruments Llc | Ultrabreitbandige mehrschichtige dielektrische Strahlteilerbeschichtung |
| US11918695B2 (en) | 2014-05-09 | 2024-03-05 | Yale University | Topical formulation of hyperbranched polymer-coated particles |
| WO2015172149A1 (en) | 2014-05-09 | 2015-11-12 | Yale University | Hyperbranched polyglycerol-coated particles and methods of making and using thereof |
| US10815276B2 (en) | 2014-05-21 | 2020-10-27 | Entrada Therapeutics, Inc. | Cell penetrating peptides and methods of making and using thereof |
| HRP20191254T1 (hr) | 2014-05-21 | 2019-10-18 | Entrada Therapeutics, Inc. | Peptidi koji prodiru u stanice i postupci za njihovu proizvodnju i uporabu |
| EP3185880B1 (en) | 2014-08-27 | 2020-02-12 | Ohio State Innovation Foundation | Improved peptidyl calcineurin inhibitors |
| WO2016081621A1 (en) | 2014-11-18 | 2016-05-26 | Yale University | Formulations for targeted release of agents under low ph conditions and methods of use thereof |
| US10682422B2 (en) | 2014-11-18 | 2020-06-16 | Yale University | Formulations for targeted release of agents under low pH conditions and methods of use thereof |
| EP3416976A2 (en) | 2016-02-16 | 2018-12-26 | Yale University | Compositions for enhancing targeted gene editing and methods of use thereof |
| WO2017143061A1 (en) | 2016-02-16 | 2017-08-24 | Yale University | Compositions and methods for treatment of cystic fibrosis |
| WO2017197128A1 (en) | 2016-05-11 | 2017-11-16 | Yale University | Poly(amine-co-ester) nanoparticles and methods of use thereof |
| US20200113821A1 (en) | 2017-04-04 | 2020-04-16 | Yale University | Compositions and methods for in utero delivery |
| WO2019070962A1 (en) | 2017-10-04 | 2019-04-11 | Ohio State Innovation Foundation | BICYCLIC PEPTIDE INHIBITORS |
| US11793884B2 (en) | 2018-01-29 | 2023-10-24 | Ohio State Innovation Foundation | Cyclic peptidyl inhibitors of CAL-PDZ binding domain |
| WO2019148194A2 (en) | 2018-01-29 | 2019-08-01 | Ohio State Innovation Foundation | Peptidyl inhibitors of calcineurin-nfat interaction |
| WO2019165183A1 (en) | 2018-02-22 | 2019-08-29 | Entrada Therapeutics, Inc. | Compositions and methods for treating mitochondrial neurogastrointestinal encephalopathy |
| EP3790890A4 (en) | 2018-05-09 | 2022-03-02 | Ohio State Innovation Foundation | CYCLIC PEPTIDES OF CELL PENETRATION WITH ONE OR MORE HYDROPHOBIC RESIDUES |
| WO2020033951A1 (en) | 2018-08-10 | 2020-02-13 | Yale University | Compositions and methods for embryonic gene editing in vitro |
| US11814464B2 (en) | 2019-04-29 | 2023-11-14 | Yale University | Poly(amine-co-ester) polymers and polyplexes with modified end groups and methods of use thereof |
| WO2020257776A1 (en) | 2019-06-21 | 2020-12-24 | Yale University | Peptide nucleic acid compositions with modified hoogsteen binding segments and methods of use thereof |
| US20220372474A1 (en) | 2019-06-21 | 2022-11-24 | Yale University | Hydroxymethyl-modified gamma-pna compositions and methods of use thereof |
| WO2021022161A1 (en) | 2019-07-31 | 2021-02-04 | Yale University | Compositions and methods for treating sickle cell disease |
| US12428658B2 (en) | 2019-11-25 | 2025-09-30 | The General Hospital Corporation | Methods and compositions for enzymatic polymerization of N3′→P5′ phosphoramidate DNA |
| CA3183351A1 (en) | 2020-06-19 | 2021-12-23 | Yale University | Poly(amine-co-ester) polymers with modified end groups and enhanced pulmonary delivery |
| US20220031633A1 (en) | 2020-07-28 | 2022-02-03 | Yale University | Poly(amine-co-ester) polymeric particles for selective pulmonary delivery |
| CA3240179A1 (en) | 2021-12-08 | 2023-06-15 | Alexandra Piotrowski-Daspit | Surface conjugation to poly(amine-co-ester) nanoparticles for targeting to cells and tissues |
| WO2023159189A1 (en) | 2022-02-18 | 2023-08-24 | Yale University | Branched poly(amine-co-ester) polymers for more efficient nucleic expression |
| GB202307563D0 (en) | 2023-05-19 | 2023-07-05 | Univ King Abdullah Sci & Tech | Methods and compositions |
| US20250032644A1 (en) | 2023-07-25 | 2025-01-30 | Massachusetts Institute Of Technology | Compositions and methods for treating fan1 associated trinucleotide repeat expansion disorders |
| CN117088825A (zh) * | 2023-10-12 | 2023-11-21 | 成都威斯津生物医药科技有限公司 | 一种可离子化脂质、含该可离子化脂质的药物组合物及其用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4999349A (en) * | 1990-03-22 | 1991-03-12 | Bristol-Myers Squibb Co. | BU-4164E - A and B, prolyl endopeptidase inhibitors |
| DE69704731D1 (de) * | 1996-02-27 | 2001-06-13 | Lilly Co Eli | Cryptophycinderivate und ihre Verwendung als antimikrotubuli Mittel |
-
2001
- 2001-08-02 EP EP01956110A patent/EP1305299A1/en not_active Withdrawn
- 2001-08-02 IL IL15386401A patent/IL153864A0/xx unknown
- 2001-08-02 AU AU2001278143A patent/AU2001278143B2/en not_active Ceased
- 2001-08-02 AU AU7814301A patent/AU7814301A/xx active Pending
- 2001-08-02 MX MXPA03000905A patent/MXPA03000905A/es not_active Application Discontinuation
- 2001-08-02 JP JP2002516274A patent/JP2004505112A/ja not_active Withdrawn
- 2001-08-02 CA CA002417064A patent/CA2417064A1/en not_active Abandoned
- 2001-08-02 WO PCT/US2001/024282 patent/WO2002010142A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002010142A1 (en) | 2002-02-07 |
| CA2417064A1 (en) | 2002-02-07 |
| IL153864A0 (en) | 2003-07-31 |
| AU2001278143B2 (en) | 2007-08-09 |
| JP2004505112A (ja) | 2004-02-19 |
| AU7814301A (en) | 2002-02-13 |
| EP1305299A1 (en) | 2003-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |