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MXPA02012743A - Moleculas tipo il-17 y usos de las mismas. - Google Patents

Moleculas tipo il-17 y usos de las mismas.

Info

Publication number
MXPA02012743A
MXPA02012743A MXPA02012743A MXPA02012743A MXPA02012743A MX PA02012743 A MXPA02012743 A MX PA02012743A MX PA02012743 A MXPA02012743 A MX PA02012743A MX PA02012743 A MXPA02012743 A MX PA02012743A MX PA02012743 A MXPA02012743 A MX PA02012743A
Authority
MX
Mexico
Prior art keywords
polypeptides
methods
molecules
amelioration
agonists
Prior art date
Application number
MXPA02012743A
Other languages
English (en)
Inventor
Shuqian Jing
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MXPA02012743A publication Critical patent/MXPA02012743A/es

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    • CCHEMISTRY; METALLURGY
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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Abstract

Polipeptidos novedosos tipo IL-17 y moleculas de acido nucleico que los codifican. Asimismo, la invencion contempla vectores, celulas huesped, agentes aglutinantes selectivos y metodos para la produccion de polipeptidos tipo IL-17. Asimismo, se contemplan metodos para el tratamiento diagnostico, mejora o prevencion de enfermedades con polipeptidos tipo IL-17, agonistas o antagonistas de los mismos.
MXPA02012743A 2000-06-22 2001-06-21 Moleculas tipo il-17 y usos de las mismas. MXPA02012743A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21312500P 2000-06-22 2000-06-22
US26615901P 2001-02-02 2001-02-02
US81038401A 2001-03-16 2001-03-16
PCT/US2001/019861 WO2002008285A2 (en) 2000-06-22 2001-06-21 Il-17 molecules and uses thereof

Publications (1)

Publication Number Publication Date
MXPA02012743A true MXPA02012743A (es) 2003-04-25

Family

ID=27395826

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012743A MXPA02012743A (es) 2000-06-22 2001-06-21 Moleculas tipo il-17 y usos de las mismas.

Country Status (9)

Country Link
US (1) US20020037524A1 (es)
EP (1) EP1294765B1 (es)
JP (1) JP2004504064A (es)
AR (1) AR030236A1 (es)
AU (2) AU2001272968C1 (es)
CA (1) CA2412626C (es)
ES (1) ES2444710T3 (es)
MX (1) MXPA02012743A (es)
WO (1) WO2002008285A2 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6562578B1 (en) 1999-01-11 2003-05-13 Schering Corporation IL-17-like cytokine binding compounds and antibodies
US7771719B1 (en) 2000-01-11 2010-08-10 Genentech, Inc. Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E
IL138930A0 (en) 1998-05-15 2001-11-25 Genentech Inc Il-17 homologies polypeptides and therapeutic uses thereof
US7767203B2 (en) 1998-08-07 2010-08-03 Ganeden Biotech, Inc. Methods for the dietary management of irritable bowel syndrome and carbohydrate malabsorption
EP2290081A3 (en) * 1999-12-23 2012-08-01 Genentech, Inc. IL-17 homologous polypeptide and therapeutic uses thereof
US20040043397A1 (en) 2000-01-11 2004-03-04 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
US7718397B2 (en) 2000-03-21 2010-05-18 Genentech, Inc. Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof
US20030096969A1 (en) 2000-06-02 2003-05-22 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20060083713A1 (en) * 2000-10-13 2006-04-20 Eli Lilly And Company Methods of using a human il-17 related polypeptide to treat disease
AU2002242142A1 (en) * 2001-02-09 2002-08-28 Johns Hopkins University A cytokine related structurally to il-17
CA2452233A1 (en) * 2001-03-26 2002-10-03 Zymogenetics, Inc. Method of inducing proliferation of retinal stem cells
US8183350B2 (en) 2002-05-04 2012-05-22 Acorda Therapeutics, Inc. Compositions and methods for promoting neuronal outgrowth
WO2004024097A2 (en) * 2002-09-16 2004-03-25 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US7959914B2 (en) 2003-05-16 2011-06-14 Acorda Therapeutics, Inc. Methods of reducing extravasation of inflammatory cells
EP2460881B1 (en) 2003-05-16 2017-05-03 Acorda Therapeutics, Inc. Proteoglycan degrading mutants for treatment of CNS
US7854927B2 (en) 2004-05-11 2010-12-21 Ganeden Biotech, Inc. Methods and compositions for the dietary management of autoimmune disorders
EP1750757B1 (en) 2004-05-18 2013-03-13 Acorda Therapeutics, Inc. Methods of purifying chondroitinase and stable formulations thereof
WO2006094384A1 (en) * 2005-03-08 2006-09-14 Genesense Technologies Inc. Use of interleukin 17e for the treatment of cancer
US9345745B2 (en) * 2005-04-29 2016-05-24 Bo Wang Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
JP2009507023A (ja) 2005-09-01 2009-02-19 シェーリング コーポレイション 自己免疫性眼炎症性疾患を処置するためのil−23およびil−17のアンタゴニストの使用
US7485295B2 (en) 2005-09-26 2009-02-03 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase ABCI mutants
EP1772733A1 (en) * 2005-10-10 2007-04-11 Institut National De La Sante Et De La Recherche Medicale (Inserm) Method for the differential diagnosis and the monitoring of Alzheimer-type dementia
CA3009034C (en) 2006-10-10 2020-08-18 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase abci mutants
MX2010012090A (es) 2008-05-05 2011-04-11 Novimmune Sa Anticuerpos anti-il 17 a/il-17f de reactividad cruzada y metodos de uso de los mismos.
WO2010014608A1 (en) * 2008-07-28 2010-02-04 University Of Louisville Research Foundation, Inc. Methods and compositions for inhibition of neutrophil exocytosis
EP3246039A1 (en) 2009-04-29 2017-11-22 Ganeden Biotech, Inc. Bacterial cell membrane formulation
KR101811886B1 (ko) 2009-05-05 2017-12-22 노비뮨 에스 에이 항―il―17f 항체 및 이의 사용 방법
WO2010133662A1 (en) * 2009-05-20 2010-11-25 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of il-17 polypeptides for use in the prevention or treatment of atherosclerosis
US11235008B2 (en) 2011-03-31 2022-02-01 Ganeden Biotech, Inc. Probiotic sports nutrition compositions
EP2809660B1 (en) 2012-02-02 2016-01-20 Ensemble Therapeutics Corporation Macrocyclic compounds for modulating il-17
CN106456745A (zh) * 2014-02-11 2017-02-22 北京艾棣维欣生物技术有限公司 具有白细胞介素‑17作为佐剂的疫苗
WO2017007960A1 (en) * 2015-07-07 2017-01-12 Fred Hutchinson Cancer Research Center Compositions, kits, and methods using interleukin-17c to promote neural growth and/or neural survival
KR102617833B1 (ko) 2016-05-06 2023-12-27 엑시큐어 오퍼레이팅 컴퍼니 인터류킨 17 수용체 mRNA의 특이적 녹다운을 위한 안티센스 올리고뉴클레오티드 (ASO)를 제시하는 리포좀성 구형 핵산 (SNA) 구축물
US11696954B2 (en) 2017-04-28 2023-07-11 Exicure Operating Company Synthesis of spherical nucleic acids using lipophilic moieties

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
WO2000037640A2 (en) * 1998-12-22 2000-06-29 Genentech, Inc. Compositions and methods for the treatment of tumor
ES2333385T3 (es) * 1997-09-17 2010-02-19 Human Genome Sciences, Inc. Proteina del tipo de interleuquina-17.
US6482923B1 (en) * 1997-09-17 2002-11-19 Human Genome Sciences, Inc. Interleukin 17-like receptor protein
WO1999035263A2 (en) * 1998-01-09 1999-07-15 Immunex Corporation Il-17rh dna and polypeptides
WO2000042187A1 (en) * 1999-01-11 2000-07-20 Schering Corporation Interleukin-17 related mammalian cytokine (il-171). polynucleotides encoding them. uses
SI1141297T1 (sl) * 1999-01-11 2010-01-29 Schering Corp Interlevkinu-17 sorodni sesalski citokini, polinukleotidi, ki jih kodirajo uporabe
AU4201000A (en) * 1999-04-05 2000-10-23 Incyte Pharmaceuticals, Inc. Molecules of the immune system
AU2001236638A1 (en) * 2000-02-04 2001-08-14 The Board Of Trustees Of The University Of Arkansas Evi27 gene sequences and protein encoded thereby
WO2001059120A2 (en) * 2000-02-08 2001-08-16 Amgen, Inc. Il-17 like molecules and uses thereof
ES2317898T3 (es) * 2000-04-18 2009-05-01 Schering Corporation Usos medicinales de agonistas y antogonistas de il-174.

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