MXPA02008064A - Combinacion novedosa de antihistaminas no sedantes que contienen sustancias las cuales influyen en la accion de leucotrienos, para tratar rinitis/conjuntivitis. - Google Patents
Combinacion novedosa de antihistaminas no sedantes que contienen sustancias las cuales influyen en la accion de leucotrienos, para tratar rinitis/conjuntivitis.Info
- Publication number
- MXPA02008064A MXPA02008064A MXPA02008064A MXPA02008064A MXPA02008064A MX PA02008064 A MXPA02008064 A MX PA02008064A MX PA02008064 A MXPA02008064 A MX PA02008064A MX PA02008064 A MXPA02008064 A MX PA02008064A MX PA02008064 A MXPA02008064 A MX PA02008064A
- Authority
- MX
- Mexico
- Prior art keywords
- leukotriene
- influence
- action
- novel combination
- containing substances
- Prior art date
Links
- 230000001387 anti-histamine Effects 0.000 title abstract 2
- 239000000739 antihistaminic agent Substances 0.000 title abstract 2
- 239000000932 sedative agent Substances 0.000 title abstract 2
- 230000001624 sedative effect Effects 0.000 title abstract 2
- 206010010741 Conjunctivitis Diseases 0.000 title 1
- 229940125715 antihistaminic agent Drugs 0.000 title 1
- 150000002617 leukotrienes Chemical class 0.000 title 1
- 206010039083 rhinitis Diseases 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- 239000003199 leukotriene receptor blocking agent Substances 0.000 abstract 2
- 229940124125 5 Lipoxygenase inhibitor Drugs 0.000 abstract 1
- 206010010744 Conjunctivitis allergic Diseases 0.000 abstract 1
- 239000004606 Fillers/Extenders Substances 0.000 abstract 1
- 239000000867 Lipoxygenase Inhibitor Substances 0.000 abstract 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 208000002205 allergic conjunctivitis Diseases 0.000 abstract 1
- 230000000172 allergic effect Effects 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 208000024998 atopic conjunctivitis Diseases 0.000 abstract 1
- 208000010668 atopic eczema Diseases 0.000 abstract 1
- 239000012752 auxiliary agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical compound C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 abstract 1
- 229960003088 loratadine Drugs 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 208000001319 vasomotor rhinitis Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
La invencion se refiere a una combinacion farmaceutica administrable topica u oralmente de una antihistamina no sedante, con excepcion de compuestos del tipo loratadina, y un antagonista de leucotrieno, seleccionado de un antagonista de leucotrieno D4, o un inhibidor de 5- Iipoxigenasa, o un antagonista de FLAP y opcionalmente soportes, extensores y agentes auxiliares convencionales, fisiologicamente inofensivos, para la profilaxis y tratamiento de rinitis alergica y/o vasomotora o conjuntivitis alergica.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10007203A DE10007203A1 (de) | 2000-02-17 | 2000-02-17 | Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis |
| PCT/EP2001/001190 WO2001060407A2 (de) | 2000-02-17 | 2001-02-05 | Neue kombination nichtsedierender antihistaminika mit substanzen, die die leukotrienwirkung beeinflussen, zur behandlung der rhinitis/konjunktivitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02008064A true MXPA02008064A (es) | 2004-04-05 |
Family
ID=7631276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02008064A MXPA02008064A (es) | 2000-02-17 | 2001-02-05 | Combinacion novedosa de antihistaminas no sedantes que contienen sustancias las cuales influyen en la accion de leucotrienos, para tratar rinitis/conjuntivitis. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6436924B2 (es) |
| EP (1) | EP1265615B1 (es) |
| JP (1) | JP5529362B2 (es) |
| KR (1) | KR100764329B1 (es) |
| CN (1) | CN1241569C (es) |
| AR (1) | AR027528A1 (es) |
| AT (1) | ATE287266T1 (es) |
| AU (1) | AU781177B2 (es) |
| BR (1) | BR0108445A (es) |
| CZ (1) | CZ296395B6 (es) |
| DE (2) | DE10007203A1 (es) |
| DK (1) | DK1265615T3 (es) |
| ES (1) | ES2236189T3 (es) |
| HU (1) | HU228927B1 (es) |
| IL (2) | IL151106A0 (es) |
| MX (1) | MXPA02008064A (es) |
| NO (1) | NO328153B1 (es) |
| NZ (1) | NZ520470A (es) |
| PL (1) | PL198357B1 (es) |
| PT (1) | PT1265615E (es) |
| RU (1) | RU2292208C2 (es) |
| SK (1) | SK285990B6 (es) |
| TW (1) | TWI296525B (es) |
| UA (1) | UA72587C2 (es) |
| WO (1) | WO2001060407A2 (es) |
| ZA (1) | ZA200206575B (es) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2373186A (en) * | 2001-02-23 | 2002-09-18 | Astrazeneca Ab | Pharmaceutical combinations of a CCR3 antagonist and a compound which is usefulreatment of asthma, allergic disease or inflammation |
| FR2833493B1 (fr) * | 2001-12-18 | 2005-09-23 | Ioltechnologie Production | Forme galenique solide et soluble pour l'administration occulaire de principes actifs et procede de fabrication d'un insert ophtalmique solide et soluble |
| AU2003264859A1 (en) * | 2001-12-21 | 2003-12-19 | Sampad Bhattacharya | Intranasal pharmaceutical compositions comprising an antihistamine and a leukotriene inhibitor |
| GB2389530B (en) | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
| JP2006508180A (ja) * | 2002-10-17 | 2006-03-09 | デコード ジェネティクス イーエッチエフ. | 心筋梗塞に対する感受性遺伝子;治療の方法 |
| US20080293750A1 (en) * | 2002-10-17 | 2008-11-27 | Anna Helgadottir | Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment |
| US7851486B2 (en) | 2002-10-17 | 2010-12-14 | Decode Genetics Ehf. | Susceptibility gene for myocardial infarction, stroke, and PAOD; methods of treatment |
| US7507531B2 (en) | 2002-10-17 | 2009-03-24 | Decode Genetics Chf. | Use of 5-lipoxygenase activating protein (FLAP) gene to assess susceptibility for myocardial infarction |
| WO2005027886A2 (en) * | 2003-09-17 | 2005-03-31 | Decode Genetics Ehf. | Methods of preventing or treating recurrence of myocardial infarction |
| US20060019269A1 (en) * | 2002-10-17 | 2006-01-26 | Decode Genetics, Inc. | Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment |
| US20040198743A1 (en) * | 2003-01-31 | 2004-10-07 | Schering Corporation | Methods for treating allergic skin and allergic ocular conditions using combinations of histamine receptor antagonists |
| US20040235807A1 (en) * | 2003-05-21 | 2004-11-25 | Weinrich Karl P. | Formulations including a topical decongestant and a topical corticosteroid suitable for nasal administration and method for treating obstructive sleep apnea |
| US20060263350A1 (en) * | 2003-09-26 | 2006-11-23 | Fairfield Clinical Trials Llc | Combination antihistamine medication |
| WO2005030331A1 (en) * | 2003-09-26 | 2005-04-07 | Fairfield Clinical Trials, Llc | Combination antihistamine medication |
| US8158362B2 (en) | 2005-03-30 | 2012-04-17 | Decode Genetics Ehf. | Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype |
| US20100216863A1 (en) * | 2004-01-30 | 2010-08-26 | Decode Genetics Ehf. | Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment |
| SI1713473T1 (sl) * | 2004-02-06 | 2013-06-28 | Meda Pharma Gmbh & Co. Kg | Kombinacija antiholinergikov in glukokortikoidov za dolgotranjno zdravljenje astme in KOPB |
| PL1713471T3 (pl) * | 2004-02-06 | 2012-06-29 | Meda Pharma Gmbh & Co Kg | Kombinacja środków antycholinergicznych i inhibitorów fosfodiesterazy typu 4 do leczenia chorób oddechowych |
| PE20060484A1 (es) * | 2004-07-14 | 2006-07-06 | Ucb Farchim Sa | Preparaciones farmaceuticas liquidas que comprenden un compuesto de benzhidril piperizina |
| LT2522365T (lt) | 2004-11-24 | 2017-02-10 | Meda Pharmaceuticals Inc. | Kompozicijos, apimančios azelastiną, ir jų panaudojimo būdai |
| US8758816B2 (en) | 2004-11-24 | 2014-06-24 | Meda Pharmaceuticals Inc. | Compositions comprising azelastine and methods of use thereof |
| US20070020330A1 (en) | 2004-11-24 | 2007-01-25 | Medpointe Healthcare Inc. | Compositions comprising azelastine and methods of use thereof |
| CA2595791C (en) * | 2005-03-16 | 2013-10-08 | Meda Pharma Gmbh & Co. Kg | The combination of anticholinergics and leukotriene receptor antagonists for the treatment of respiratory diseases |
| US7405302B2 (en) * | 2005-10-11 | 2008-07-29 | Amira Pharmaceuticals, Inc. | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| PL2098248T3 (pl) | 2005-12-21 | 2012-11-30 | Meda Pharma Gmbh & Co Kg | Kombinacja antycholinergików, glukokortykoidów i beta2-agonistów do leczenia chorób zapalnych |
| WO2007126865A2 (en) * | 2006-03-30 | 2007-11-08 | Patrin Pharma | Leukotriene antagonists via nasal drug delivery |
| WO2008067566A1 (en) | 2006-11-30 | 2008-06-05 | Amira Pharmaceuticals, Inc. | Compositions and treatments comprising 5-lipoxygenase-activating protein inhibitors and nitric oxide modulators |
| EP2222299B1 (en) * | 2007-11-19 | 2011-11-23 | Bausch & Lomb Incorporated | Use of levocabastine for modulating generation of pro-inflammatory cytokines |
| JP2012520880A (ja) * | 2009-03-17 | 2012-09-10 | アーシエックス セラピューティックス, インコーポレイテッド | ケトチフェンの眼科用製剤および使用方法 |
| MX2011009802A (es) | 2009-03-17 | 2011-11-02 | Aciex Therapeutics Inc | Formulaciones oftalmicas de cetirizina y metodos de uso. |
| US8569273B2 (en) | 2009-03-17 | 2013-10-29 | Aciex Therapeutics, Inc. | Ophthalmic formulations of cetirizine and methods of use |
| SG175390A1 (en) | 2009-04-29 | 2011-12-29 | Amarin Corp Plc | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| KR101418404B1 (ko) * | 2012-01-06 | 2014-07-10 | 한미약품 주식회사 | 레보세티리진 또는 이의 약학적으로 허용가능한 염 및 몬테루카스트 또는 이의 약학적으로 허용가능한 염을 함유하는 안정한 경구투여용 약학 제제 |
| WO2014160440A1 (en) | 2013-03-13 | 2014-10-02 | Flatley Discovery Lab | Pyridazinone compounds and methods for the treatment of cystic fibrosis |
| ES2745041T3 (es) | 2013-03-13 | 2020-02-27 | Inflammatory Response Res Inc | Uso de levocetirizina y montelukast en el tratamiento de trastornos autoinmunitarios |
| KR101555908B1 (ko) * | 2013-12-19 | 2015-09-25 | 한미약품 주식회사 | 몬테루카스트 또는 이의 약제학적으로 허용 가능한 염을 포함하는 액상 제제 및 이의 제조방법 |
| DK3102209T3 (da) | 2014-02-04 | 2021-07-12 | Bioscience Pharma Partners Llc | Anvendelse af flap-hæmmere til at reducere neuroinflammationsmedieret læsion i centralnervesystemet |
| WO2016044095A1 (en) | 2014-09-15 | 2016-03-24 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
| CA3126021A1 (en) * | 2019-01-11 | 2020-07-16 | Naegis Pharmaceuticals Inc. | Leukotriene synthesis inhibitors |
| US12257172B2 (en) | 2019-02-28 | 2025-03-25 | Coloplast A/S | Sensor patch for attachment to a base plate |
| CN110721189A (zh) * | 2019-11-19 | 2020-01-24 | 贵州云峰药业有限公司 | 一种皮肤消毒剂 |
| CA3166799A1 (en) | 2020-02-03 | 2021-08-12 | Vered Rosenberger | Topical montelukast formulations |
| US12233055B2 (en) | 2020-02-03 | 2025-02-25 | Taro Pharmaceutical Industries Ltd. | Topical Montelukast formulations |
| CN116284470B (zh) * | 2023-02-15 | 2024-08-02 | 广西中医药大学 | 一种海蛇尾多糖硫酸酯衍生物的制备方法及应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3813384A (en) | 1972-01-17 | 1974-05-28 | Asta Werke Ag Chem Fab | Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof |
| ATE84968T1 (de) | 1987-11-13 | 1993-02-15 | Asta Medica Ag | Azelastin enthaltende arzneimittel zur anwendung in der nase und/oder am auge. |
| WO1989010143A1 (en) * | 1988-04-27 | 1989-11-02 | Schering Corporation | Certain paf antagonist antihistamine combinations and methods |
| US5276044A (en) * | 1991-08-14 | 1994-01-04 | Allergan, Inc. | Leukotriene receptor antagonist and antihistamine complex pharmaceutical compositions |
| PT815860E (pt) * | 1992-08-03 | 2006-08-31 | Sepracor Inc | Carboxilato de terfenadina e tratamento de desordens alergicas. |
| CA2245162A1 (en) * | 1996-02-08 | 1997-08-14 | Merck & Co., Inc. | Method of treatment and pharmaceutical composition |
| DE19610882A1 (de) * | 1996-03-20 | 1997-09-25 | Dresden Arzneimittel | Neue 1,3,5-trisubstituierte Indazol-Derivate mit antiasthmatischer, antiallergischer, entzündungshemmender und immunmodulierender Wirkung, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US5900421A (en) * | 1997-02-11 | 1999-05-04 | Sepracor Inc. | Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine |
| IL131492A0 (en) * | 1997-04-30 | 2001-01-28 | Warner Lambert Co | Topical nasal antiinflammatory compositions |
| US6242179B1 (en) | 1997-12-17 | 2001-06-05 | Incyte Pharmaceuticals, Inc. | Human phosphatases |
| SK286103B6 (sk) * | 1997-12-23 | 2008-03-05 | Schering Corporation | Farmaceutický prostriedok na liečenie respiračných a kožných ochorení s obsahom aspoň jedného antagonistu leukotriénu a aspoň jedného antihistaminikaa jeho použitie |
| US6194431B1 (en) * | 1998-04-14 | 2001-02-27 | Paul D. Rubin | Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors |
-
2000
- 2000-02-17 DE DE10007203A patent/DE10007203A1/de not_active Withdrawn
-
2001
- 2001-02-05 BR BR0108445-3A patent/BR0108445A/pt not_active Application Discontinuation
- 2001-02-05 KR KR1020027010599A patent/KR100764329B1/ko not_active Expired - Fee Related
- 2001-02-05 CN CNB018050476A patent/CN1241569C/zh not_active Expired - Fee Related
- 2001-02-05 DE DE50105126T patent/DE50105126D1/de not_active Expired - Lifetime
- 2001-02-05 SK SK1175-2002A patent/SK285990B6/sk not_active IP Right Cessation
- 2001-02-05 PL PL355818A patent/PL198357B1/pl unknown
- 2001-02-05 EP EP01911591A patent/EP1265615B1/de not_active Expired - Lifetime
- 2001-02-05 DK DK01911591T patent/DK1265615T3/da active
- 2001-02-05 WO PCT/EP2001/001190 patent/WO2001060407A2/de not_active Ceased
- 2001-02-05 AT AT01911591T patent/ATE287266T1/de active
- 2001-02-05 JP JP2001559503A patent/JP5529362B2/ja not_active Expired - Fee Related
- 2001-02-05 ES ES01911591T patent/ES2236189T3/es not_active Expired - Lifetime
- 2001-02-05 AU AU40584/01A patent/AU781177B2/en not_active Ceased
- 2001-02-05 PT PT01911591T patent/PT1265615E/pt unknown
- 2001-02-05 RU RU2002123345/15A patent/RU2292208C2/ru not_active IP Right Cessation
- 2001-02-05 HU HU0204079A patent/HU228927B1/hu not_active IP Right Cessation
- 2001-02-05 NZ NZ520470A patent/NZ520470A/en not_active IP Right Cessation
- 2001-02-05 MX MXPA02008064A patent/MXPA02008064A/es active IP Right Grant
- 2001-02-05 CZ CZ20022700A patent/CZ296395B6/cs not_active IP Right Cessation
- 2001-02-05 IL IL15110601A patent/IL151106A0/xx active IP Right Grant
- 2001-02-12 TW TW090103054A patent/TWI296525B/zh not_active IP Right Cessation
- 2001-02-15 US US09/784,640 patent/US6436924B2/en not_active Expired - Lifetime
- 2001-02-16 AR ARP010100731A patent/AR027528A1/es not_active Application Discontinuation
- 2001-05-02 UA UA2002097483A patent/UA72587C2/uk unknown
-
2002
- 2002-08-06 IL IL151106A patent/IL151106A/en not_active IP Right Cessation
- 2002-08-12 NO NO20023818A patent/NO328153B1/no not_active IP Right Cessation
- 2002-08-16 ZA ZA200206575A patent/ZA200206575B/xx unknown
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