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MX9408969A - Composisciones farmaceuticas que comprenden microparticulas biodegradables y biocompatibles para el tratamiento de transtornos psicoticos, su uso y procedimiento para prepararlas. - Google Patents

Composisciones farmaceuticas que comprenden microparticulas biodegradables y biocompatibles para el tratamiento de transtornos psicoticos, su uso y procedimiento para prepararlas.

Info

Publication number
MX9408969A
MX9408969A MX9408969A MX9408969A MX9408969A MX 9408969 A MX9408969 A MX 9408969A MX 9408969 A MX9408969 A MX 9408969A MX 9408969 A MX9408969 A MX 9408969A MX 9408969 A MX9408969 A MX 9408969A
Authority
MX
Mexico
Prior art keywords
hydrogen
alkyl
carbon atoms
independently selected
group
Prior art date
Application number
MX9408969A
Other languages
English (en)
Inventor
Jean Louis Mesens
Michael E Rickey
Thomas J Atkins
Original Assignee
Janssen Pharmaceutica Nv
Medisorb Technologies Internat
L P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22551225&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9408969(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv, Medisorb Technologies Internat, L P filed Critical Janssen Pharmaceutica Nv
Publication of MX9408969A publication Critical patent/MX9408969A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Una composicion farmacéutica que comprende micropartículas biodegradables y biocompatibles que contiene 1,2-benzazol de la formula (I); o una sal ácida de adicion farmacéuticamente aceptable del mismo, en donde, R es hidrogeno o alquilo de C1-6; R1 y R2 son independientemente hidrogeno, halogeno, hidroxi, alquiloxi de C1-6 y alquilo de C1-6; X es O o S; Alc es alcanodilo de C1-4; y R3 es hidrogenon donde R4 y R5 son independientemente hidrogeno o alquilo de C1-6; A es un radical bivalente -CH2-CH2-, -CH2-CH2-CH2- o -CR6=CR7-; en donde R6 y R7 son hidrogeno, halogeno, amino o alquilo de C1-6; y R8 es hidrogeno o hidroxilo; dentro de una matriz polimérica.
MX9408969A 1993-11-19 1994-11-18 Composisciones farmaceuticas que comprenden microparticulas biodegradables y biocompatibles para el tratamiento de transtornos psicoticos, su uso y procedimiento para prepararlas. MX9408969A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15440393A 1993-11-19 1993-11-19

Publications (1)

Publication Number Publication Date
MX9408969A true MX9408969A (es) 1997-03-29

Family

ID=22551225

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9408969A MX9408969A (es) 1993-11-19 1994-11-18 Composisciones farmaceuticas que comprenden microparticulas biodegradables y biocompatibles para el tratamiento de transtornos psicoticos, su uso y procedimiento para prepararlas.

Country Status (29)

Country Link
US (11) US5688801A (es)
EP (1) EP0729357B1 (es)
JP (1) JP3645906B2 (es)
KR (1) KR100354270B1 (es)
CN (1) CN1074923C (es)
AT (1) ATE288270T1 (es)
AU (1) AU694147B2 (es)
BG (1) BG63246B1 (es)
CL (1) CL2004001182A1 (es)
CZ (1) CZ293764B6 (es)
DE (1) DE69434258T2 (es)
DK (1) DK0729357T3 (es)
ES (1) ES2236700T3 (es)
FI (1) FI117122B (es)
HU (1) HU219487B (es)
IL (1) IL111647A (es)
MX (1) MX9408969A (es)
MY (1) MY113298A (es)
NO (1) NO309226B1 (es)
NZ (1) NZ276088A (es)
PL (1) PL314481A1 (es)
PT (1) PT729357E (es)
RO (1) RO119224B1 (es)
RU (1) RU2178695C2 (es)
SG (1) SG47445A1 (es)
SI (1) SI0729357T1 (es)
SK (1) SK282231B6 (es)
WO (1) WO1995013814A1 (es)
ZA (1) ZA949191B (es)

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FI117122B (fi) 2006-06-30
US20020098233A1 (en) 2002-07-25
BG63246B1 (bg) 2001-07-31
AU8142594A (en) 1995-06-06
NZ276088A (en) 1999-07-29
US5688801A (en) 1997-11-18
JPH09505286A (ja) 1997-05-27
ES2236700T3 (es) 2005-07-16
NO962040D0 (no) 1996-05-20
CZ137396A3 (en) 1996-08-14
RO119224B1 (ro) 2004-06-30
HU9501942D0 (en) 1995-09-28
SI0729357T1 (en) 2005-06-30
DK0729357T3 (da) 2005-06-06
US5965168A (en) 1999-10-12
SK282231B6 (sk) 2001-12-03
US20060182810A1 (en) 2006-08-17
NO962040L (no) 1996-07-15

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