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MX9403275A - METHYLENDIOXI [3, '4': 6,7] INDOLIZINO- [1,2-B] QUINOLINONAS SUBSTITUTED. - Google Patents

METHYLENDIOXI [3, '4': 6,7] INDOLIZINO- [1,2-B] QUINOLINONAS SUBSTITUTED.

Info

Publication number
MX9403275A
MX9403275A MX9403275A MX9403275A MX9403275A MX 9403275 A MX9403275 A MX 9403275A MX 9403275 A MX9403275 A MX 9403275A MX 9403275 A MX9403275 A MX 9403275A MX 9403275 A MX9403275 A MX 9403275A
Authority
MX
Mexico
Prior art keywords
substituted
quinolinonas
methylendioxi
indolizino
compounds
Prior art date
Application number
MX9403275A
Other languages
Spanish (es)
Inventor
William Dennis Kingsbury
Israil Pendrak
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of MX9403275A publication Critical patent/MX9403275A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Se describen en la presente composiciones demetilendioxiindolizino[1,2-b]quinolinonas, substituidas, antivirales, quecomprenden dichos compuestos, y un método para tratar infecciones viralesusando dichos compuestos.Described herein are antiviral, substituted demethylenedioxyindolizino [1,2-b] quinolinones compositions comprising said compounds, and a method of treating viral infections using said compounds.

MX9403275A 1993-05-03 1994-05-03 METHYLENDIOXI [3, '4': 6,7] INDOLIZINO- [1,2-B] QUINOLINONAS SUBSTITUTED. MX9403275A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5713393A 1993-05-03 1993-05-03
US21365794A 1994-03-15 1994-03-15

Publications (1)

Publication Number Publication Date
MX9403275A true MX9403275A (en) 1995-01-31

Family

ID=26736111

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9403275A MX9403275A (en) 1993-05-03 1994-05-03 METHYLENDIOXI [3, '4': 6,7] INDOLIZINO- [1,2-B] QUINOLINONAS SUBSTITUTED.

Country Status (7)

Country Link
EP (1) EP0699201A1 (en)
JP (1) JPH08509742A (en)
AU (1) AU684777B2 (en)
CA (1) CA2161980A1 (en)
MX (1) MX9403275A (en)
NZ (1) NZ266094A (en)
WO (1) WO1994025465A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883255A (en) * 1990-10-31 1999-03-16 Smithkline Beecham Corporation Substituted indolizino 1,2-b!quinolinones

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5829793B2 (en) * 1975-02-07 1983-06-24 日本ケミフア （株） Process for producing 7-alkoxycarbonyl-8-methylindolizino[1,2-b]quinolin-9(11H)-one
US4981968A (en) * 1987-03-31 1991-01-01 Research Triangle Institute Synthesis of camptothecin and analogs thereof
CA1332413C (en) * 1987-06-25 1994-10-11 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
US5225404A (en) * 1989-11-06 1993-07-06 New York University Methods of treating colon tumors with tumor-inhibiting camptothecin compounds
JPH06502642A (en) * 1990-10-31 1994-03-24 スミスクライン・ビーチャム・コーポレイション Substituted indolizino[1,2-b]quinolinone
ATE136898T1 (en) * 1991-10-29 1996-05-15 Glaxo Wellcome Inc WATER SOLUBLE CAMPTOTHECINE DERIVATIVES
JPH05191297A (en) * 1992-01-10 1993-07-30 Fujitsu Ltd Serial/parallel conversion circuit

Also Published As

Publication number Publication date
EP0699201A4 (en) 1996-01-22
WO1994025465A1 (en) 1994-11-10
AU684777B2 (en) 1998-01-08
NZ266094A (en) 1997-10-24
AU6670494A (en) 1994-11-21
EP0699201A1 (en) 1996-03-06
JPH08509742A (en) 1996-10-15
CA2161980A1 (en) 1994-11-10

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