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MX9306419A - Bifenilos trisustituidos, procedimiento para su obtencion y medicamentos que los contienen. - Google Patents

Bifenilos trisustituidos, procedimiento para su obtencion y medicamentos que los contienen.

Info

Publication number
MX9306419A
MX9306419A MX9306419A MX9306419A MX9306419A MX 9306419 A MX9306419 A MX 9306419A MX 9306419 A MX9306419 A MX 9306419A MX 9306419 A MX9306419 A MX 9306419A MX 9306419 A MX9306419 A MX 9306419A
Authority
MX
Mexico
Prior art keywords
biphenyls
trisustituted
procedure
obtaining
containing medicines
Prior art date
Application number
MX9306419A
Other languages
English (en)
Inventor
Ulrich E Muller
Matthias Muller-Gliemann
Martin Beuck Stanislav Kazda
Stefan Wohlfeil Andreas Knorr
Johannes-Peter Stasch
Siegfried Zaiss
Jurgen Dressel
Peter Fey Rudol Hanko
Walter Hubsch Thomas Kramer
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX9306419A publication Critical patent/MX9306419A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Los bifenilos trisustituidos se obtienen al transformar las piridonas correspondientes con compuestos halogenados de bifenilmetilo. Los bifenilos trisustituídos pueden usarse como sustancia activa en medicamentos.
MX9306419A 1992-10-23 1993-10-15 Bifenilos trisustituidos, procedimiento para su obtencion y medicamentos que los contienen. MX9306419A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4235933 1992-10-23
DE4319041A DE4319041A1 (de) 1992-10-23 1993-06-08 Trisubstituierte Biphenyle

Publications (1)

Publication Number Publication Date
MX9306419A true MX9306419A (es) 1994-05-31

Family

ID=25919778

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9306419A MX9306419A (es) 1992-10-23 1993-10-15 Bifenilos trisustituidos, procedimiento para su obtencion y medicamentos que los contienen.

Country Status (22)

Country Link
US (2) US5596006A (es)
EP (1) EP0594019B1 (es)
JP (1) JPH06199838A (es)
KR (1) KR100304225B1 (es)
CN (1) CN1040435C (es)
AT (1) ATE189893T1 (es)
AU (1) AU670315B2 (es)
CA (1) CA2108814A1 (es)
CZ (1) CZ283482B6 (es)
DE (2) DE4319041A1 (es)
DK (1) DK0594019T3 (es)
ES (1) ES2145021T3 (es)
FI (1) FI934646L (es)
GR (1) GR3033207T3 (es)
HU (1) HUT65819A (es)
IL (1) IL107333A (es)
MX (1) MX9306419A (es)
NO (1) NO304651B1 (es)
NZ (1) NZ250002A (es)
PT (1) PT594019E (es)
SK (1) SK279675B6 (es)
TW (1) TW248555B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4319040A1 (de) * 1992-10-23 1994-04-28 Bayer Ag Alkoxymethylsubstituierte Pyridonbiphenyle
AU2001277731A1 (en) 2000-08-09 2002-02-18 Welfide Corporation Fused bicyclic amide compounds and medicinal use thereof
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
AU2002351412B2 (en) * 2001-12-21 2010-05-20 Exelixis Patent Company Llc Modulators of LXR
ES2251292B1 (es) * 2004-04-20 2007-07-01 Inke, S.A. Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de sus intermedios de sintesis.
WO2006130901A1 (en) * 2005-06-07 2006-12-14 Bayer Healthcare Ag Control of metabolic abnormalities
DE102005030522A1 (de) * 2005-06-30 2007-01-04 Bayer Healthcare Ag Salz des Embusartans
TWI448284B (zh) 2007-04-24 2014-08-11 Theravance Inc 雙效抗高血壓劑
DE102007028320A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028406A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028407A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028319A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
EP2138178A1 (en) 2008-06-28 2009-12-30 Bayer Schering Pharma Aktiengesellschaft Oxazolidninones for the treatment fo chronic obstructive pulmonary disease (COPD) and/or asthma
SG10201609322QA (en) 2012-05-10 2017-01-27 Bayer Pharma AG Antibodies capable of binding to the coagulation factor xi and/or its activated form factor xia and uses thereof
KR102614588B1 (ko) 2018-08-20 2023-12-18 삼성디스플레이 주식회사 표시 장치의 제조 방법
WO2024159724A1 (zh) * 2023-02-03 2024-08-08 科莱博(江苏)科技股份有限公司 一种邻联苯基噁唑啉化合物及其合成方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
EP0403158A3 (en) * 1989-06-14 1991-12-18 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
SG52330A1 (en) * 1989-06-14 1998-09-28 Smithkline Beecham Corp Imidazolyl-alkenoic acids
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
EP0485410A1 (en) * 1989-07-06 1992-05-20 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern A detector for monitoring low molecular weight compounds
CA2027937A1 (en) * 1989-10-25 1991-04-26 Richard M. Keenan Substituted 5-¬ (tetrazolyl)alkenyl|imidazoles
WO1991009697A1 (fr) * 1989-12-25 1991-07-11 Nippon Steel Corporation Toles a base d'un compose intermetallique de titane-aluminium et procede de production d'une telle tole
EP0453210A3 (en) * 1990-04-19 1993-01-13 Imperial Chemical Industries Plc Pyridine derivatives
NZ238624A (en) * 1990-06-19 1994-08-26 Meiji Seika Co Pyridine derivatives, compositions, preparations and use thereof
US5250548A (en) * 1990-09-10 1993-10-05 Abbott Laboratories Angiotensin II receptor antagonists
IL100917A0 (en) * 1991-02-16 1992-11-15 Fisons Plc Pyridinone and pyrimidinone derivatives,their preparation and pharmaceutical compositions containing them
CN1068109A (zh) * 1991-02-16 1993-01-20 菲索斯有限公司 新的血管紧张肽ii拮抗剂及其制剂的制备和应用
DE4221583A1 (de) * 1991-11-12 1993-05-13 Bayer Ag Substituierte biphenylpyridone
US5310928A (en) * 1991-11-18 1994-05-10 E. I. Du Pont De Nemours And Company Process for preparing biphenyltetrazole compounds
DK0643704T3 (da) * 1991-11-18 2004-01-19 Merck & Co Inc Tetrazolylphenylboronsyremellemprodukter til syntese af All-receptor antagonister
US5130439A (en) * 1991-11-18 1992-07-14 Lo Young S Tetrazolylphenylboronic acid intermediates for the synthesis of AII receptor antagonists
US5206374A (en) * 1991-11-18 1993-04-27 E. I. Du Pont De Nemours And Company Process for preparing tetrazolylphenylboronic acid intermediates
DE4319040A1 (de) * 1992-10-23 1994-04-28 Bayer Ag Alkoxymethylsubstituierte Pyridonbiphenyle

Also Published As

Publication number Publication date
EP0594019A1 (de) 1994-04-27
EP0594019B1 (de) 2000-02-23
CA2108814A1 (en) 1994-04-24
HU9302997D0 (en) 1994-01-28
SK279675B6 (sk) 1999-02-11
FI934646A0 (fi) 1993-10-21
FI934646A7 (fi) 1994-04-24
SK116993A3 (en) 1994-11-09
CZ221793A3 (en) 1994-05-18
ES2145021T3 (es) 2000-07-01
CN1040435C (zh) 1998-10-28
NO933591L (no) 1994-04-25
GR3033207T3 (en) 2000-08-31
PT594019E (pt) 2000-08-31
IL107333A (en) 1998-01-04
FI934646L (fi) 1994-04-24
TW248555B (es) 1995-06-01
JPH06199838A (ja) 1994-07-19
US5863930A (en) 1999-01-26
DE59309956D1 (de) 2000-03-30
HUT65819A (en) 1994-07-28
ATE189893T1 (de) 2000-03-15
KR100304225B1 (ko) 2004-05-10
KR940009174A (ko) 1994-05-20
IL107333A0 (en) 1994-01-25
AU670315B2 (en) 1996-07-11
AU4754193A (en) 1994-05-05
US5596006A (en) 1997-01-21
NZ250002A (en) 1995-03-28
NO304651B1 (no) 1999-01-25
DE4319041A1 (de) 1994-04-28
CN1089260A (zh) 1994-07-13
DK0594019T3 (da) 2000-07-03
NO933591D0 (no) 1993-10-07
CZ283482B6 (cs) 1998-04-15

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees