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MX9100317A - Nuevos compuestos de beta-lactama,procedimiento para su preparacion y composiciones farmaceuticas que los contienen - Google Patents

Nuevos compuestos de beta-lactama,procedimiento para su preparacion y composiciones farmaceuticas que los contienen

Info

Publication number
MX9100317A
MX9100317A MX9100317A MX9100317A MX9100317A MX 9100317 A MX9100317 A MX 9100317A MX 9100317 A MX9100317 A MX 9100317A MX 9100317 A MX9100317 A MX 9100317A MX 9100317 A MX9100317 A MX 9100317A
Authority
MX
Mexico
Prior art keywords
lactama
compounds
procedure
preparation
pharmaceutical compositions
Prior art date
Application number
MX9100317A
Other languages
English (en)
Inventor
John Hargreaves Bateson
George Burton
Stephen Christopher Marti Fell
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909016189A external-priority patent/GB9016189D0/en
Priority claimed from GB919109540A external-priority patent/GB9109540D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of MX9100317A publication Critical patent/MX9100317A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MX9100317A 1990-07-24 1991-07-22 Nuevos compuestos de beta-lactama,procedimiento para su preparacion y composiciones farmaceuticas que los contienen MX9100317A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909016189A GB9016189D0 (en) 1990-07-24 1990-07-24 Novel compounds
GB919109540A GB9109540D0 (en) 1991-05-02 1991-05-02 Novel compounds

Publications (1)

Publication Number Publication Date
MX9100317A true MX9100317A (es) 1992-02-28

Family

ID=26297372

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9100317A MX9100317A (es) 1990-07-24 1991-07-22 Nuevos compuestos de beta-lactama,procedimiento para su preparacion y composiciones farmaceuticas que los contienen

Country Status (26)

Country Link
EP (2) EP0540606A1 (es)
JP (2) JP2851428B2 (es)
KR (1) KR100189075B1 (es)
CN (2) CN1061046C (es)
AP (1) AP832A (es)
AT (1) ATE185567T1 (es)
AU (1) AU648329B2 (es)
CA (2) CA2359744C (es)
CZ (1) CZ6493A3 (es)
DE (2) DE122006000065I2 (es)
DK (1) DK0540609T3 (es)
ES (1) ES2137162T3 (es)
FI (1) FI930270L (es)
GR (1) GR3031711T3 (es)
HU (1) HUT63628A (es)
IE (1) IE912569A1 (es)
IL (1) IL98909A0 (es)
LU (1) LU91290I2 (es)
MX (1) MX9100317A (es)
MY (1) MY106399A (es)
NL (1) NL300249I2 (es)
NO (1) NO930226L (es)
NZ (1) NZ239061A (es)
PT (1) PT98426A (es)
WO (2) WO1992001695A1 (es)
YU (1) YU129691A (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9125645D0 (en) * 1991-12-03 1992-01-29 Smithkline Beecham Plc Novel compounds
DE69331047T2 (de) * 1992-01-22 2002-03-21 Pfizer Inc., New York 2-isocephem und -oxacephemderivate,verfahren zu deren herstellung, deren zwischenprodukte und verwendung als antibakterielle mittel
GB9212609D0 (en) * 1992-06-13 1992-07-29 Smithkline Beecham Plc Novel compounds
GB9213567D0 (en) * 1992-06-26 1992-08-12 Smithkline Beecham Plc Novel compounds
GB9424847D0 (en) * 1994-12-09 1995-02-08 Smithkline Beecham Plc Novel process
GB2300856A (en) * 1995-05-16 1996-11-20 Pfizer Ltd Beta-lactam preparation
WO1998014421A1 (en) * 1996-10-02 1998-04-09 Daiichi Pharmaceutical Co., Ltd. Method for esterifying carboxylic compounds
FR2776292B1 (fr) * 1998-03-20 2004-09-10 Oncopharm Cephalotaxanes porteurs de chaine laterale et leur procede de synthese
GB0019124D0 (en) * 2000-08-03 2000-09-27 Pfizer Novel process
KR100526379B1 (ko) * 2000-12-04 2005-11-08 화이자 프로덕츠 인크. 세팔로스포린 제조에 유용한 커플링법 및 중간체
KR100526380B1 (ko) * 2000-12-04 2005-11-08 화이자 프로덕츠 인크. 세팔로스포린을 제조하는데 유용한 방법 및 에스테르유도체
US7378408B2 (en) 2001-11-30 2008-05-27 Pfizer Inc. Methods of treatment and formulations of cephalosporin
KR100710555B1 (ko) 2001-12-04 2007-04-24 에스케이 주식회사 광학적으로 순수한 (ｒ)-폼 또는 (ｓ)-폼의테트라히드로퓨라닐 케톤의 제조방법
PL2794627T3 (pl) 2011-12-22 2019-04-30 Alios Biopharma Inc Podstawione nukleozydy, nukleotydy i ich analogi
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
EA027929B1 (ru) 2012-05-25 2017-09-29 Янссен Сайенсиз Айрлэнд Юси Нуклеозиды на основе урацила и спирооксетана
EA201590943A1 (ru) 2012-12-21 2016-01-29 Алиос Биофарма, Инк. Замещенные нуклеозиды, нуклеотиды и их аналоги
CN105254648B (zh) * 2015-11-13 2018-04-03 广东温氏大华农生物科技有限公司 一种头孢维星及其钠盐的合成方法
GB2575261B (en) 2018-07-02 2022-03-09 Norbrook Lab Ltd Intermediates in the synthesis of C3-substituted cephalosporins
US11401339B2 (en) 2018-08-23 2022-08-02 Seagen Inc. Anti-TIGIT antibodies
PT4069691T (pt) 2019-12-06 2024-12-18 Vertex Pharma Tetrahidrofuranos substituídos como moduladores dos canais de sódio
TWI874791B (zh) 2020-02-18 2025-03-01 美商基利科學股份有限公司 抗病毒化合物
EP4644394A2 (en) 2020-02-18 2025-11-05 Gilead Sciences, Inc. Antiviral compounds
TWI794742B (zh) 2020-02-18 2023-03-01 美商基利科學股份有限公司 抗病毒化合物
CN111620893B (zh) * 2020-06-08 2021-12-14 重庆医药高等专科学校 C-3位四氢呋喃取代的头孢菌素-铁载体耦合物及其制备方法和应用
KR20230170745A (ko) 2021-04-16 2023-12-19 길리애드 사이언시즈, 인코포레이티드 아미드를 사용한 카르바뉴클레오시드를 제조하는 방법
GEAP202416430A (en) 2021-06-04 2024-03-25 Vertex Pharma N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamides as modulators of sodium channels
WO2023023527A1 (en) 2021-08-18 2023-02-23 Gilead Sciences, Inc. Phospholipid compounds and methods of making and using the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793448A (fr) * 1971-12-31 1973-06-28 Roussel Uclaf Procede de preparation de nouveaux derives des cephalosporines et produits obtenus
FR2197573A1 (en) * 1972-09-07 1974-03-29 Roussel Uclaf 7-substd-phenylacetamido-cephalosporin derivs - - antibiotics active against streptococci and staphylococci
BE791161A (fr) * 1972-01-03 1973-05-09 Beecham Group Ltd Procede pour la preparation d'analogues des cephalosporines
BE791160A (fr) * 1972-01-03 1973-05-09 Beecham Group Ltd Nouveaux cephemes substitues
NL7305936A (es) * 1972-05-05 1973-11-07
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
GB8821797D0 (en) * 1988-09-16 1988-10-19 Beecham Group Plc Novel compounds
DK0395219T3 (da) * 1989-03-30 1999-02-15 Pfizer Cephalosporiner og deres homologer, fremgangsmåde til deres fremstilling og farmaceutiske præparater

Also Published As

Publication number Publication date
WO1992001696A1 (en) 1992-02-06
CN1061046C (zh) 2001-01-24
JP2851428B2 (ja) 1999-01-27
HU9300177D0 (en) 1993-04-28
CN1060469A (zh) 1992-04-22
AP9100305A0 (en) 1991-07-31
CA2359744A1 (en) 1992-02-06
IE912569A1 (en) 1992-01-29
AU648329B2 (en) 1994-04-21
YU129691A (sh) 1994-01-20
LU91290I2 (fr) 2007-01-22
ES2137162T3 (es) 1999-12-16
IL98909A0 (en) 1992-07-15
KR930701456A (ko) 1993-06-11
PT98426A (pt) 1992-05-29
CA2359744C (en) 2007-02-13
NO930226L (no) 1993-03-23
ATE185567T1 (de) 1999-10-15
CN1223859A (zh) 1999-07-28
JPH05509305A (ja) 1993-12-22
FI930270A0 (fi) 1993-01-22
CA2087967A1 (en) 1992-01-25
CZ6493A3 (en) 1994-04-13
CA2087967C (en) 2002-09-10
DE122006000065I2 (de) 2007-09-13
AU8222491A (en) 1992-02-18
FI930270A7 (fi) 1993-03-22
GR3031711T3 (en) 2000-02-29
EP0540606A1 (en) 1993-05-12
NL300249I1 (nl) 2007-02-01
WO1992001695A1 (en) 1992-02-06
JPH05509089A (ja) 1993-12-16
KR100189075B1 (ko) 1999-06-01
EP0540609A1 (en) 1993-05-12
NZ239061A (en) 1993-11-25
CN1111410C (zh) 2003-06-18
HUT63628A (en) 1993-09-28
DE69131714T2 (de) 2000-02-24
EP0540609B1 (en) 1999-10-13
DK0540609T3 (da) 1999-12-27
AP832A (en) 2000-05-03
FI930270L (fi) 1993-03-22
NO930226D0 (no) 1993-01-22
DE69131714D1 (de) 1999-11-18
DE122006000065I1 (de) 2007-03-01
MY106399A (en) 1995-05-30
NL300249I2 (en) 2007-02-01

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