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MX380940B - Compuestos de pirazol y metodo para elaborar y usar los compuestos. - Google Patents

Compuestos de pirazol y metodo para elaborar y usar los compuestos.

Info

Publication number
MX380940B
MX380940B MX2017013413A MX2017013413A MX380940B MX 380940 B MX380940 B MX 380940B MX 2017013413 A MX2017013413 A MX 2017013413A MX 2017013413 A MX2017013413 A MX 2017013413A MX 380940 B MX380940 B MX 380940B
Authority
MX
Mexico
Prior art keywords
compounds
compositions
preparing
pyrazole
disclosed
Prior art date
Application number
MX2017013413A
Other languages
English (en)
Other versions
MX2017013413A (es
Inventor
Yan Chen
Darren Mcmurtrie
Kelley Ryan
Kin Tso
Hui Li
Jack Maung
Rajinder Singh
Thilo Heckrodt
Vanessa Taylor
Rose Yen
Original Assignee
Rigel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rigel Pharmaceuticals Inc filed Critical Rigel Pharmaceuticals Inc
Publication of MX2017013413A publication Critical patent/MX2017013413A/es
Publication of MX380940B publication Critical patent/MX380940B/es

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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Abstract

Las realizaciones divulgadas tratan de inhibidores de cinasas asociadas con receptores de interleucina (IRAK) y composiciones que comprenden estos inhibidores. También se divulgan métodos para elaborar y usar los compuestos y las composiciones. Los compuestos y/o las composiciones divulgados se pueden usar para tratar o prevenir una enfermedad o afección asociada con IRAK.
MX2017013413A 2015-04-22 2016-04-22 Compuestos de pirazol y metodo para elaborar y usar los compuestos. MX380940B (es)

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