MX384445B - Sistema para tratamiento con gas de un implante de células. - Google Patents
Sistema para tratamiento con gas de un implante de células.Info
- Publication number
- MX384445B MX384445B MX2016003615A MX2016003615A MX384445B MX 384445 B MX384445 B MX 384445B MX 2016003615 A MX2016003615 A MX 2016003615A MX 2016003615 A MX2016003615 A MX 2016003615A MX 384445 B MX384445 B MX 384445B
- Authority
- MX
- Mexico
- Prior art keywords
- gas
- subsystem
- gas generator
- cell containment
- implantable
- Prior art date
Links
- 239000007943 implant Substances 0.000 title abstract 5
- 239000007789 gas Substances 0.000 abstract 7
- 230000001413 cellular effect Effects 0.000 abstract 4
- 210000004153 islets of langerhan Anatomy 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000003915 cell function Effects 0.000 abstract 1
- 230000003833 cell viability Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000005868 electrolysis reaction Methods 0.000 abstract 1
- 230000006870 function Effects 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 210000000496 pancreas Anatomy 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 230000035899 viability Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M2005/006—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for gases, e.g. CO2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0208—Oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7536—General characteristics of the apparatus with filters allowing gas passage, but preventing liquid passage, e.g. liquophobic, hydrophobic, water-repellent membranes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
- Y02E60/30—Hydrogen technology
- Y02E60/36—Hydrogen production from non-carbon containing sources, e.g. by water electrolysis
Landscapes
- Health & Medical Sciences (AREA)
- Transplantation (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
- Prostheses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Bioinformatics & Cheminformatics (AREA)
Abstract
Sistema para el tratamiento con gas de implantes celulares. El sistema mejora la viabilidad y la función de los implantes celulares, particularmente aquellos con alta densidad celular, para uso en medicina humana o veterinaria. El sistema utiliza un subsistema generador de gas electroquímico miniaturizado que suministra continuamente oxígeno y/o hidrógeno a células dentro de un subsistema de contención de células implantable e inmuno-aislado para facilitar la viabilidad y la función celular en alta densidad celular mientras se reduce al mínimo el tamaño total del implante. El subsistema de contención de células está equipado con características para permitir el suministro de gas a través de un tubo poroso o compartimientos de gas internos permeables sólo a gases dentro del subsistema de contención de células implantable. Además, el subsistema generador de gas incluye componentes que permiten el acceso a agua para electrólisis mientras está implantado, promoviendo así la aplicabilidad a largo plazo del subsistema generador de gas. Una aplicación del sistema es un implante de islote pancreático (o análogos de islotes pancreáticos) para el tratamiento de diabetes tipo 1 (T1D) que sería considerado un páncreas bio-artificial.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361881654P | 2013-09-24 | 2013-09-24 | |
| PCT/US2014/057295 WO2015048184A1 (en) | 2013-09-24 | 2014-09-24 | System for gas treatment of a cell implant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016003615A MX2016003615A (es) | 2016-10-26 |
| MX384445B true MX384445B (es) | 2025-03-14 |
Family
ID=52744433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016003615A MX384445B (es) | 2013-09-24 | 2014-09-24 | Sistema para tratamiento con gas de un implante de células. |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US10231817B2 (es) |
| EP (1) | EP3049020B1 (es) |
| JP (1) | JP6749239B2 (es) |
| KR (1) | KR102323291B1 (es) |
| CN (2) | CN105792775B (es) |
| AU (1) | AU2014326794B2 (es) |
| BR (1) | BR112016006378A2 (es) |
| CA (2) | CA2924681C (es) |
| IL (1) | IL244714B (es) |
| MX (1) | MX384445B (es) |
| SA (1) | SA516370789B1 (es) |
| SG (1) | SG11201602232UA (es) |
| WO (1) | WO2015048184A1 (es) |
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| EP3534834A4 (en) * | 2016-11-03 | 2020-05-13 | Arizona Board of Regents on behalf of the University of Arizona | Encapsulation device systems with oxygen sensors with or without exogenous oxygen supply |
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| CN116919648A (zh) | 2016-11-03 | 2023-10-24 | 代表亚利桑那大学的亚利桑那董事会 | 有或无氧气输送的堆叠组织包封装置的系统 |
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-
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- 2014-09-24 WO PCT/US2014/057295 patent/WO2015048184A1/en not_active Ceased
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- 2014-09-24 BR BR112016006378A patent/BR112016006378A2/pt not_active Application Discontinuation
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| KR102323291B1 (ko) | 2021-11-05 |
| US20240189088A1 (en) | 2024-06-13 |
| US12070383B2 (en) | 2024-08-27 |
| MX2016003615A (es) | 2016-10-26 |
| IL244714A0 (en) | 2016-04-21 |
| US11701215B2 (en) | 2023-07-18 |
| SG11201602232UA (en) | 2016-04-28 |
| AU2014326794B2 (en) | 2019-03-21 |
| CN105792775B (zh) | 2019-02-19 |
| CN110101485A (zh) | 2019-08-09 |
| EP3049020A1 (en) | 2016-08-03 |
| CA2924681A1 (en) | 2015-04-02 |
| EP3049020A4 (en) | 2017-07-26 |
| EP3049020B1 (en) | 2022-06-15 |
| US20150112247A1 (en) | 2015-04-23 |
| JP2016530980A (ja) | 2016-10-06 |
| BR112016006378A2 (pt) | 2017-08-01 |
| US20190336267A1 (en) | 2019-11-07 |
| CA3059017C (en) | 2021-05-25 |
| CN105792775A (zh) | 2016-07-20 |
| WO2015048184A1 (en) | 2015-04-02 |
| CA3059017A1 (en) | 2015-04-02 |
| CA2924681C (en) | 2019-12-31 |
| CN110101485B (zh) | 2021-07-06 |
| JP6749239B2 (ja) | 2020-09-02 |
| AU2014326794A1 (en) | 2016-04-21 |
| KR20160060115A (ko) | 2016-05-27 |
| SA516370789B1 (ar) | 2020-03-04 |
| US10231817B2 (en) | 2019-03-19 |
| IL244714B (en) | 2020-06-30 |
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