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MX367666B - Composiciones y métodos para cuantificar una secuencia de ácido nucleico en una muestra. - Google Patents

Composiciones y métodos para cuantificar una secuencia de ácido nucleico en una muestra.

Info

Publication number
MX367666B
MX367666B MX2016004384A MX2016004384A MX367666B MX 367666 B MX367666 B MX 367666B MX 2016004384 A MX2016004384 A MX 2016004384A MX 2016004384 A MX2016004384 A MX 2016004384A MX 367666 B MX367666 B MX 367666B
Authority
MX
Mexico
Prior art keywords
methods
sample
quantifying
compositions
nucleic acid
Prior art date
Application number
MX2016004384A
Other languages
English (en)
Inventor
Shaffer Daniel
A Judice Stephen
Original Assignee
Envirologix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49328090&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX367666(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Envirologix Inc filed Critical Envirologix Inc
Publication of MX367666B publication Critical patent/MX367666B/es

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a composiciones y métodos para cuantificar la detección de un oligonucleótido objetivo en una muestra en tiempo real. Estos métodos son compatibles con los oligonucleótidos objetivo amplificados al utilizar una reacción NEAR.
MX2016004384A 2012-04-09 2013-04-09 Composiciones y métodos para cuantificar una secuencia de ácido nucleico en una muestra. MX367666B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261621975P 2012-04-09 2012-04-09
PCT/US2013/035750 WO2013155056A1 (en) 2012-04-09 2013-04-09 Compositions and methods for quantifying a nucleic acid sequence in a sample

Publications (1)

Publication Number Publication Date
MX367666B true MX367666B (es) 2019-08-30

Family

ID=49328090

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016004384A MX367666B (es) 2012-04-09 2013-04-09 Composiciones y métodos para cuantificar una secuencia de ácido nucleico en una muestra.
MX2014012214A MX338296B (es) 2012-04-09 2013-04-09 Composiciones y metodos para cuantificar una secuencia de acido nucleico en una muestra.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2014012214A MX338296B (es) 2012-04-09 2013-04-09 Composiciones y metodos para cuantificar una secuencia de acido nucleico en una muestra.

Country Status (18)

Country Link
US (8) US9096897B2 (es)
EP (3) EP3587587B1 (es)
JP (4) JP5801513B2 (es)
KR (4) KR101570951B1 (es)
CN (2) CN114134207A (es)
AU (3) AU2013246080C1 (es)
BR (1) BR112014025262A8 (es)
CA (1) CA2869971C (es)
DK (2) DK2836609T4 (es)
ES (2) ES3011408T3 (es)
FI (1) FI3587587T3 (es)
IN (1) IN2014DN08831A (es)
MX (2) MX367666B (es)
NZ (2) NZ723570A (es)
RU (2) RU2732589C2 (es)
UA (2) UA116205C2 (es)
WO (1) WO2013155056A1 (es)
ZA (3) ZA201408116B (es)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013004044A2 (pt) 2010-08-13 2016-07-05 Envirologix Inc composições e métodos para quantificação de uma sequência de ácido nucleico em uma amostra.
ES3011408T3 (en) 2012-04-09 2025-04-07 Envirologix Inc Compositions and methods for quantifying a nucleic acid sequence in a sample
WO2015164494A1 (en) * 2014-04-22 2015-10-29 Envirologix, Inc. Compositions and methods for enhancing and/or predicting dna amplification
US10100370B2 (en) 2014-04-30 2018-10-16 Envirologix Inc. Compositions and methods for detecting huanglongbing
WO2016059474A2 (en) * 2014-10-14 2016-04-21 Abbott Japan Co., Ltd Sequence conversion and signal amplifier dna having poly dna spacer sequences and detection methods using same
US10793922B2 (en) * 2014-10-20 2020-10-06 Envirologix Inc. Compositions and methods for detecting an RNA virus
EP3250709B1 (en) * 2015-01-30 2019-12-25 Envirologix Inc. Compositions and methods for rapid detection of salmonella
WO2016123029A1 (en) 2015-01-30 2016-08-04 Envirologix Inc. Substrate molecule
EP3314245A4 (en) * 2015-06-25 2019-02-27 Roswell Biotechnologies, Inc BIOMOLECULAR SENSORS AND METHOD
BR112018001222A2 (pt) * 2015-07-20 2018-09-25 Envirologix Inc. composições e métodos para a detecção rápida de salmonella serovar d1.
US20180320228A1 (en) * 2015-10-30 2018-11-08 Alere Inc. Determination of polymorphisms using isothermal nucleic acid amplification
US10329601B2 (en) 2015-12-28 2019-06-25 Ionian Technologies, Inc. Nicking and extension amplification reaction (NEAR) of Streptococcus species
JP7280590B2 (ja) 2016-01-28 2023-05-24 ロズウェル バイオテクノロジーズ，インコーポレイテッド 大スケールの分子電子工学センサアレイを使用する被分析物を測定するための方法および装置
EP4137808A1 (en) 2016-01-28 2023-02-22 Roswell Biotechnologies, Inc. Method of making a sequencing device
KR102734671B1 (ko) 2016-02-09 2024-11-25 로스웰 엠이 아이엔씨. 전자 비표지 dna 및 게놈 시퀀싱
US10597767B2 (en) 2016-02-22 2020-03-24 Roswell Biotechnologies, Inc. Nanoparticle fabrication
GB201611469D0 (en) 2016-06-30 2016-08-17 Lumiradx Tech Ltd Improvements in or relating to nucleic acid amplification processes
US9829456B1 (en) 2016-07-26 2017-11-28 Roswell Biotechnologies, Inc. Method of making a multi-electrode structure usable in molecular sensing devices
CA3052062A1 (en) 2017-01-10 2018-07-19 Roswell Biotechnologies, Inc. Methods and systems for dna data storage
WO2018136148A1 (en) 2017-01-19 2018-07-26 Roswell Biotechnologies, Inc. Solid state sequencing devices comprising two dimensional layer materials
EP3615685B1 (en) 2017-04-25 2025-02-19 Roswell Biotechnologies, Inc Enzymatic circuits for molecular sensors
US10508296B2 (en) 2017-04-25 2019-12-17 Roswell Biotechnologies, Inc. Enzymatic circuits for molecular sensors
CA3057155A1 (en) 2017-05-09 2018-11-15 Roswell Biotechnologies, Inc. Binding probe circuits for molecular sensors
US10538808B2 (en) 2017-05-26 2020-01-21 Vibrant Holdings, Llc Photoactive compounds and methods for biomolecule detection and sequencing
TWI754652B (zh) * 2017-07-10 2022-02-11 英商盧米瑞德克斯英國有限公司 核酸擴增方法中或相關之改良
US11371955B2 (en) 2017-08-30 2022-06-28 Roswell Biotechnologies, Inc. Processive enzyme molecular electronic sensors for DNA data storage
KR20200083444A (ko) 2017-08-31 2020-07-08 아이오니안 테크놀로지스, 엘엘씨 호흡기 세포융합 바이러스 종의 니킹 및 연장 증폭 반응(near)
CN111373051A (zh) 2017-10-10 2020-07-03 罗斯威尔生命技术公司 用于无扩增dna数据存储的方法、装置和系统
GB2569965A (en) 2018-01-04 2019-07-10 Lumiradx Uk Ltd Improvements in or relating to amplification of nucleic acids
CN108588252A (zh) * 2018-03-29 2018-09-28 杭州泰熙生物技术有限公司 一种寄生虫检测试剂盒及其检测方法
EP3790985A4 (en) 2018-05-09 2022-02-16 Vibrant Holdings, LLC METHOD OF SYNTHESIS OF A POLYNUCLEOTIDARRAY USING PHOTOACTIVATED AGENTS
JP2021528091A (ja) * 2018-06-26 2021-10-21 ザ・ブロード・インスティテュート・インコーポレイテッド Ｃｒｉｓｐｒダブルニッカーゼに基づく増幅の組成物、システム、及び方法
GB201812149D0 (en) 2018-07-25 2018-09-05 Sense Biodetection Ltd Nucleic acid detection method
KR102154628B1 (ko) 2019-01-03 2020-09-10 베트올 (주) 반정량 수평류 면역진단 기술을 이용한 랄스토니아 솔라나세아룸과 푸사리움 옥시스포룸의 동시 진단 방법
KR102199394B1 (ko) * 2019-07-01 2021-01-06 한국화학연구원 이중분자비콘과 산화그래핀을 포함하는 핵산 검출용 조성물 및 이를 이용한 핵산 검출의 비색신호 증폭 방법
KR102531590B1 (ko) * 2019-07-16 2023-05-11 고려대학교 산학협력단 절단효소 인식부위의 미러링 결합에 의한 표적핵산의 검출 방법 및 핵산 검출용 조성물
CN110408678A (zh) * 2019-07-26 2019-11-05 宁儿医院股份有限公司 单管型多重微生物检测体系及其即时检测方法
WO2021226205A1 (en) * 2020-05-07 2021-11-11 Bioskryb, Inc. Detection of low abundance nucleic acids
CA3206960A1 (en) * 2021-02-02 2022-08-11 Rhodx, Inc. Synthetic polynucleotides and methods for selectively amplifying alleles
CN118541495A (zh) * 2021-12-08 2024-08-23 麻省理工学院 多核苷酸的低温等温扩增
US20250382670A1 (en) * 2022-05-14 2025-12-18 Jiangsu Code Biomedical Technology Co., Ltd. Novel compositions and methods for cell-free dna detection
WO2024006552A1 (en) * 2022-07-01 2024-01-04 Sherlock Biosciences, Inc. Ambient temperature nucleic acid amplification and detection
WO2024030985A1 (en) 2022-08-04 2024-02-08 Abbott Laboratories Assays for detecting monkeypox virus
WO2025049450A1 (en) 2023-08-28 2025-03-06 Abbott Molecular, Inc. Assays for detecting bk virus (bkv)
WO2025049451A1 (en) 2023-08-28 2025-03-06 Abbott Molecular, Inc. Assays for detecting cytomegalovirus (cmv) or epstein-bar virus (ebv)

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455166A (en) † 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
WO1994003635A1 (en) 1992-08-04 1994-02-17 Institute Of Molecular Biology & Biotechnology Rapid amplification and detection of nucleic acids
US5648211A (en) 1994-04-18 1997-07-15 Becton, Dickinson And Company Strand displacement amplification using thermophilic enzymes
US5629179A (en) 1995-03-17 1997-05-13 Novagen, Inc. Method and kit for making CDNA library
AT402203B (de) 1995-06-13 1997-03-25 Himmler Gottfried Dipl Ing Dr Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren
EP0914462A4 (en) * 1996-03-18 2002-05-22 Molecular Biology Resources Amplification of target nucleic acid sequences
WO1998002582A2 (en) * 1996-07-16 1998-01-22 Gen-Probe Incorporated Methods for detecting and amplifying nucleic acid sequences using modified oligonucleotides having increased target specific t¿m?
GB9716231D0 (en) 1997-07-31 1997-10-08 Amersham Int Ltd Base analogues
AU1366299A (en) 1997-10-27 1999-05-17 Boston Probes, Inc. Methods, kits and compositions pertaining to pna molecular beacons
US5952202A (en) 1998-03-26 1999-09-14 The Perkin Elmer Corporation Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification
WO2000028084A1 (en) 1998-11-06 2000-05-18 Molecular Biology Resources, Inc. Isothermal nucleic acid amplification methods
US6436677B1 (en) 2000-03-02 2002-08-20 Promega Corporation Method of reverse transcription
AU2001274869A1 (en) 2000-05-20 2001-12-03 The Regents Of The University Of Michigan Method of producing a dna library using positional amplification
US6191267B1 (en) 2000-06-02 2001-02-20 New England Biolabs, Inc. Cloning and producing the N.BstNBI nicking endonuclease
ATE312942T1 (de) * 2000-10-25 2005-12-15 Hoffmann La Roche Amplifizierung unter verwendung von modifizierten primern
CA2433330A1 (en) * 2000-12-27 2002-07-25 Invitrogen Corporation Primers and methods for the detection and discrimination of nucleic acids
US20030138800A1 (en) 2001-07-15 2003-07-24 Keck Graduate Institute Exponential amplification of nucleic acids using nicking agents
AU2002313683A1 (en) * 2001-07-15 2003-03-03 Keck Graduate Institute Nucleic acid amplification using nicking agents
KR20040028991A (ko) * 2001-08-20 2004-04-03 다카라 바이오 가부시키가이샤 핵산 증폭 방법
US6617137B2 (en) 2001-10-15 2003-09-09 Molecular Staging Inc. Method of amplifying whole genomes without subjecting the genome to denaturing conditions
US6977148B2 (en) 2001-10-15 2005-12-20 Qiagen Gmbh Multiple displacement amplification
US7399590B2 (en) 2002-02-21 2008-07-15 Asm Scientific, Inc. Recombinase polymerase amplification
US20030211483A1 (en) 2002-05-09 2003-11-13 Schroeder Benjamin G. Methods for the enrichment of low-abundance polynucleotides
US7662594B2 (en) 2002-09-20 2010-02-16 New England Biolabs, Inc. Helicase-dependent amplification of RNA
CA2498764C (en) 2002-09-20 2015-11-10 New England Biolabs, Inc. Helicase dependent amplification of nucleic acids
WO2004067726A2 (en) 2003-01-29 2004-08-12 Keck Graduate Institute Isothermal reactions for the amplification of oligonucleotides
JP4380305B2 (ja) 2003-11-21 2009-12-09 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
US20090017452A1 (en) 2004-03-05 2009-01-15 University Of Chicago Methods and compositions relating to the pharmacogenetics of different gene variants
US20060115838A1 (en) 2004-10-19 2006-06-01 Trevigen Inc. Real-time detection of amplicons using nucleic acid repair enzymes
EP2319940A1 (en) * 2005-01-04 2011-05-11 Hitachi Chemical Company, Ltd. Primer generation rolling circle amplification
JP4555136B2 (ja) * 2005-03-31 2010-09-29 本田技研工業株式会社 燃料電池の電気システム、燃料電池車両及び電力供給方法
ES2420831T3 (es) 2005-07-25 2013-08-27 Alere San Diego, Inc. Procedimientos para multiplexar la ampliación de la recombinasa polimerasa
WO2007018601A1 (en) 2005-08-02 2007-02-15 Rubicon Genomics, Inc. Compositions and methods for processing and amplification of dna, including using multiple enzymes in a single reaction
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
US7947286B2 (en) 2005-10-07 2011-05-24 Panthera Biopharma Llc Drosophila cell lines producing recombinant secretable filovirus surface glycoproteins lacking the membrane spanning domain
US20090092967A1 (en) 2006-06-26 2009-04-09 Epoch Biosciences, Inc. Method for generating target nucleic acid sequences
US20080096257A1 (en) 2006-08-15 2008-04-24 Zuxu Yao Methods for Rapid, Single-Step Strand Displacement Amplification of Nucleic Acids
DE102006039396A1 (de) 2006-08-22 2008-03-13 Robert Bosch Gmbh Laserlichtquelle
US8399188B2 (en) 2006-09-28 2013-03-19 Illumina, Inc. Compositions and methods for nucleotide sequencing
JP2010505396A (ja) 2006-10-06 2010-02-25 ディーエヌエー ジェノテック インク リボ核酸を抽出するための安定化組成物および方法
JP2008136451A (ja) 2006-12-05 2008-06-19 Hitachi Ltd 核酸増幅法
US8202972B2 (en) 2007-01-10 2012-06-19 General Electric Company Isothermal DNA amplification
CL2008000083A1 (es) † 2007-01-12 2008-07-18 Monsanto Technology Llc Soc Or Polipeptido cristalizado de dicamba monooxigenasa (dmo); molecula que comprende una superficie de union para dicamba; celula vegetal que comprende dmo.
US20080254458A1 (en) 2007-04-10 2008-10-16 Asiagen Corporation Method of pre-treating in pleural effusion for detection of Mycobacterium tuberculosis
US20080274458A1 (en) 2007-05-01 2008-11-06 Latham Gary J Nucleic acid quantitation methods
US9689031B2 (en) * 2007-07-14 2017-06-27 Ionian Technologies, Inc. Nicking and extension amplification reaction for the exponential amplification of nucleic acids
WO2009020609A2 (en) 2007-08-06 2009-02-12 Nanogen, Inc. Isolation of nucleic acids molecules using modified solid supports
US20090197254A1 (en) 2007-12-14 2009-08-06 Ming-Chou Lee Variant scorpion primers for nucleic acid amplification and detection
WO2009135093A2 (en) 2008-04-30 2009-11-05 Integrated Dna Technologies, Inc. Rnase-h-based assays utilizing modified rna monomers
US10760074B2 (en) 2008-09-03 2020-09-01 Takara Bio Inc. Composition for detection of RNA
WO2010083561A1 (en) 2009-01-21 2010-07-29 Human Genetic Signatures Pty Ltd Improved isothermal strand displacement amplification
CN102428191A (zh) 2009-03-18 2012-04-25 塞昆纳姆股份有限公司 热稳定性内切核酸酶在产生报道分子中的应用
WO2010126913A1 (en) 2009-04-27 2010-11-04 Gen-Probe Incorporated Methods and kits for use in the selective amplification of target sequences
BR112013004044A2 (pt) * 2010-08-13 2016-07-05 Envirologix Inc composições e métodos para quantificação de uma sequência de ácido nucleico em uma amostra.
EP2420579A1 (en) 2010-08-17 2012-02-22 QIAGEN GmbH Helicase dependent isothermal amplification using nicking enzymes
CA2849023C (en) 2011-09-15 2022-07-19 David A. Shafer Probe:antiprobe compositions for high specificity dna or rna detection
EP2798089B1 (en) 2011-12-30 2018-05-23 Bio-rad Laboratories, Inc. Methods and compositions for performing nucleic acid amplification reactions
ES3011408T3 (en) 2012-04-09 2025-04-07 Envirologix Inc Compositions and methods for quantifying a nucleic acid sequence in a sample
CA2877368C (en) 2012-06-29 2021-07-13 General Electric Company Kit for isothermal dna amplification starting from an rna template
JP2014082936A (ja) 2012-10-19 2014-05-12 Kyoto Univ 変異型逆転写酵素
WO2015164494A1 (en) 2014-04-22 2015-10-29 Envirologix, Inc. Compositions and methods for enhancing and/or predicting dna amplification
US10100370B2 (en) 2014-04-30 2018-10-16 Envirologix Inc. Compositions and methods for detecting huanglongbing
US10793922B2 (en) 2014-10-20 2020-10-06 Envirologix Inc. Compositions and methods for detecting an RNA virus
CA2965657A1 (en) 2014-10-28 2016-05-06 Envirologix Inc. Sample preparation vessels, microfluidic circuits, and systems and methods for sample preparation, extraction, and analysis
EP3250709B1 (en) 2015-01-30 2019-12-25 Envirologix Inc. Compositions and methods for rapid detection of salmonella

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