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MX359949B - Anticuerpos para troponina i y metodos de uso de los mismos. - Google Patents

Anticuerpos para troponina i y metodos de uso de los mismos.

Info

Publication number
MX359949B
MX359949B MX2015001161A MX2015001161A MX359949B MX 359949 B MX359949 B MX 359949B MX 2015001161 A MX2015001161 A MX 2015001161A MX 2015001161 A MX2015001161 A MX 2015001161A MX 359949 B MX359949 B MX 359949B
Authority
MX
Mexico
Prior art keywords
antibodies
troponin
methods
diagnosis
patient
Prior art date
Application number
MX2015001161A
Other languages
English (en)
Inventor
N Ziemann Robert
E Brophy Susan
Tu Bailin
Huang Dagang
D Tyner Joan
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX359949B publication Critical patent/MX359949B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4716—Muscle proteins, e.g. myosin, actin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a una molécula de ácido nucleico aislada que comprende una secuencia de ácido nucleico que codifica para un anticuerpo o fragmento de unión a antígeno del mismo producida mediante una línea celular de ovario de hámster chino (CHO), referido como Tnl 19C7 AM1 hG1 CHO 204, designado mediante el número de depósito PTA-9816 del Colección de Cultivos Americano Tipo (ATCC).
MX2015001161A 2009-02-24 2010-02-23 Anticuerpos para troponina i y metodos de uso de los mismos. MX359949B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/391,937 US8030026B2 (en) 2009-02-24 2009-02-24 Antibodies to troponin I and methods of use thereof
PCT/US2010/024979 WO2010099079A1 (en) 2009-02-24 2010-02-23 Antibodies to troponin i and methods of use thereof

Publications (1)

Publication Number Publication Date
MX359949B true MX359949B (es) 2018-10-17

Family

ID=42102721

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2011008938A MX2011008938A (es) 2009-02-24 2010-02-23 Anticuerpos a troponina i y metodos de uso de los mismos.
MX2015001161A MX359949B (es) 2009-02-24 2010-02-23 Anticuerpos para troponina i y metodos de uso de los mismos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2011008938A MX2011008938A (es) 2009-02-24 2010-02-23 Anticuerpos a troponina i y metodos de uso de los mismos.

Country Status (9)

Country Link
US (4) US8030026B2 (es)
EP (2) EP2853540A1 (es)
JP (3) JP6055593B2 (es)
CN (1) CN102421795B (es)
BR (1) BRPI1007867B8 (es)
CA (1) CA2753541C (es)
ES (1) ES2525799T3 (es)
MX (2) MX2011008938A (es)
WO (1) WO2010099079A1 (es)

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US20120195900A1 (en) * 2010-12-22 2012-08-02 Abbott Laboratories Tri-variable domain binding proteins and uses thereof
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US8603759B2 (en) 2011-12-06 2013-12-10 Panasonic Corporation Recombinant protein capable of binding specifically and quickly to troponin I derived from human myocardium
US8663933B2 (en) * 2011-12-16 2014-03-04 Panasonic Corporation Recombinant protein capable of binding specifically and quickly to troponin I derived from human myocardium
US8603760B2 (en) * 2011-12-20 2013-12-10 Panasonic Corporation Recombinant protein capable of binding specifically and quickly to troponin I derived from human myocardium
JP5550797B2 (ja) * 2012-05-24 2014-07-16 パナソニック株式会社 ヒト心筋由来トロポニンｉに特異的にかつ速やかに結合できる変異体タンパク質
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WO2014192202A1 (ja) * 2013-05-29 2014-12-04 パナソニックヘルスケア株式会社 ヒト心筋由来トロポニンｉに特異的にかつ速やかに結合できる組み換えタンパク質
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US11147498B2 (en) 2016-03-31 2021-10-19 Abbott Laboratories Decision tree based systems and methods for estimating the risk of acute coronary syndrome
WO2017180876A1 (en) 2016-04-13 2017-10-19 Abbott Laboratories Cardiac troponin i detection during pregnancy for cardiovascular disease identification and risk assessment
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US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
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CN111018976B (zh) * 2018-10-10 2022-04-01 东莞市朋志生物科技有限公司 一种抗人心肌肌钙蛋白i的重组抗体
CN111018974B (zh) * 2018-10-10 2022-04-01 东莞市朋志生物科技有限公司 一种抗人心肌肌钙蛋白i的重组抗体
CN111018980B (zh) * 2018-10-10 2021-12-03 东莞市朋志生物科技有限公司 一种抗人心肌肌钙蛋白i的抗体及其应用
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CA2753541C (en) 2018-07-17
MX2011008938A (es) 2012-04-02
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EP2401292A1 (en) 2012-01-04
US20100216720A1 (en) 2010-08-26
US20120076803A1 (en) 2012-03-29
EP2401292B1 (en) 2014-10-29
CN102421795B (zh) 2015-11-25
ES2525799T3 (es) 2014-12-30
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WO2010099079A1 (en) 2010-09-02
USRE45763E1 (en) 2015-10-20
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