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MX2024011247A - Nucleasas quiméricas y modificadas geneticamente - Google Patents

Nucleasas quiméricas y modificadas geneticamente

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Publication number
MX2024011247A
MX2024011247A MX2024011247A MX2024011247A MX2024011247A MX 2024011247 A MX2024011247 A MX 2024011247A MX 2024011247 A MX2024011247 A MX 2024011247A MX 2024011247 A MX2024011247 A MX 2024011247A MX 2024011247 A MX2024011247 A MX 2024011247A
Authority
MX
Mexico
Prior art keywords
engineered
chimeric nucleases
nucleases
chimeric
num
Prior art date
Application number
MX2024011247A
Other languages
English (en)
Inventor
Brian C Thomas
Alan Brooks
Christopher Brown
Cristina Noel Butterfield
Daniela S A Goltsman
Jyun-Liang Lin
Isabel Nocedal
Morayma M Temoche-Diaz
Original Assignee
Metagenomi Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metagenomi Inc filed Critical Metagenomi Inc
Publication of MX2024011247A publication Critical patent/MX2024011247A/es

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    • C12N9/14—Hydrolases (3)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

En la presente descripción se describen nucleasas modificadas genéticamente y sistemas de nucleasas, que incluyen nucleasas quiméricas y sistemas de nucleasas quiméricas. Las nucleasas quiméricas y modificadas genéticamente descritas en la presente descripción incluyen nucleasa guiada por ácido nucleico. Adicionalmente, en la presente descripción se describen métodos para generar nucleasas modificadas genéticamente y métodos para usarlas.
MX2024011247A 2022-03-14 2024-09-12 Nucleasas quiméricas y modificadas geneticamente MX2024011247A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263319725P 2022-03-14 2022-03-14
US202263335542P 2022-04-27 2022-04-27
US202263392814P 2022-07-27 2022-07-27
US202363482294P 2023-01-30 2023-01-30
PCT/US2023/064351 WO2023178115A2 (en) 2022-03-14 2023-03-14 Engineered and chimeric nucleases

Publications (1)

Publication Number Publication Date
MX2024011247A true MX2024011247A (es) 2025-01-09

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ID=88024579

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Application Number Title Priority Date Filing Date
MX2024011247A MX2024011247A (es) 2022-03-14 2024-09-12 Nucleasas quiméricas y modificadas geneticamente

Country Status (9)

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US (1) US20250002886A1 (es)
EP (1) EP4493682A2 (es)
JP (1) JP2025510622A (es)
KR (1) KR20240158989A (es)
CN (1) CN119095954A (es)
AU (1) AU2023235279A1 (es)
CA (1) CA3254301A1 (es)
MX (1) MX2024011247A (es)
WO (1) WO2023178115A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022335499A1 (en) * 2021-08-27 2024-02-22 Metagenomi, Inc. Enzymes with ruvc domains

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WO2023178115A2 (en) 2023-09-21
KR20240158989A (ko) 2024-11-05
AU2023235279A1 (en) 2024-10-03
EP4493682A2 (en) 2025-01-22
JP2025510622A (ja) 2025-04-15
US20250002886A1 (en) 2025-01-02
CN119095954A (zh) 2024-12-06
CA3254301A1 (en) 2023-09-21

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