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MX2023013912A - Metodos para inhibir ras. - Google Patents

Metodos para inhibir ras.

Info

Publication number
MX2023013912A
MX2023013912A MX2023013912A MX2023013912A MX2023013912A MX 2023013912 A MX2023013912 A MX 2023013912A MX 2023013912 A MX2023013912 A MX 2023013912A MX 2023013912 A MX2023013912 A MX 2023013912A MX 2023013912 A MX2023013912 A MX 2023013912A
Authority
MX
Mexico
Prior art keywords
methods
inhibiting ras
inhibiting
ras
disclosure
Prior art date
Application number
MX2023013912A
Other languages
English (en)
Inventor
Kyle Seamon
Original Assignee
Revolution Medicines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Revolution Medicines Inc filed Critical Revolution Medicines Inc
Publication of MX2023013912A publication Critical patent/MX2023013912A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La divulgación presenta métodos para inhibir las proteínas RAS. La divulgación también contiene métodos para el tratamiento del cáncer.
MX2023013912A 2021-05-25 2022-05-25 Metodos para inhibir ras. MX2023013912A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163192837P 2021-05-25 2021-05-25
PCT/US2022/030823 WO2022251292A1 (en) 2021-05-25 2022-05-25 Methods for inhibiting ras

Publications (1)

Publication Number Publication Date
MX2023013912A true MX2023013912A (es) 2024-02-12

Family

ID=82115695

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023013912A MX2023013912A (es) 2021-05-25 2022-05-25 Metodos para inhibir ras.

Country Status (11)

Country Link
US (1) US20240277796A1 (es)
EP (1) EP4346898A1 (es)
JP (1) JP2024521774A (es)
KR (1) KR20240026526A (es)
CN (2) CN117715658A (es)
AU (1) AU2022281343A1 (es)
CA (1) CA3219533A1 (es)
IL (1) IL308771A (es)
MX (1) MX2023013912A (es)
TW (1) TW202313631A (es)
WO (1) WO2022251292A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11566007B2 (en) 2019-11-04 2023-01-31 Revolution Medicines, Inc. Ras inhibitors
CR20230165A (es) 2020-09-15 2023-06-02 Revolution Medicines Inc Derivados indólicos como inhibidores de ras en el tratamiento del cáncer
CR20230558A (es) 2021-05-05 2024-01-24 Revolution Medicines Inc Inhibidores de ras para el tratamiento del cáncer
AR127308A1 (es) 2021-10-08 2024-01-10 Revolution Medicines Inc Inhibidores ras
TW202330553A (zh) * 2022-01-10 2023-08-01 美商銳新醫藥公司 Ras抑制劑
EP4532503A1 (en) * 2022-06-01 2025-04-09 F. Hoffmann-La Roche AG Haloindole macrocyclic compounds for the treatment of cancer
KR20250085767A (ko) 2022-09-29 2025-06-12 광조우 조요 파마테크 컴퍼니 리미티드 거대고리 유도체 및 이의 적용
CN120813588A (zh) 2023-02-14 2025-10-17 豪夫迈·罗氏有限公司 用于治疗癌症的三环化合物
AU2024241633A1 (en) * 2023-03-30 2025-11-06 Revolution Medicines, Inc. Compositions for inducing ras gtp hydrolysis and uses thereof
TW202446387A (zh) * 2023-04-06 2024-12-01 瑞士商赫孚孟拉羅股份公司 用於治療癌症之三環化合物
WO2024229406A1 (en) 2023-05-04 2024-11-07 Revolution Medicines, Inc. Combination therapy for a ras related disease or disorder
WO2025019318A2 (en) * 2023-07-14 2025-01-23 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2025162395A1 (zh) * 2024-02-01 2025-08-07 山东先声生物制药有限公司 吲哚衍生物作为ras抑制剂及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200197391A1 (en) 2018-12-21 2020-06-25 Revolution Medicines, Inc. Compounds that participate in cooperative binding and uses thereof
DE102019122206B4 (de) 2019-08-19 2021-07-08 Webasto SE Dachmodul zur Bildung eines Fahrzeugdachs mit Umfeldsensor
US11608346B2 (en) 2019-11-04 2023-03-21 Revolution Medicines, Inc. Ras inhibitors
US11566007B2 (en) 2019-11-04 2023-01-31 Revolution Medicines, Inc. Ras inhibitors
EP4054720A1 (en) 2019-11-04 2022-09-14 Revolution Medicines, Inc. Ras inhibitors
CR20230165A (es) 2020-09-15 2023-06-02 Revolution Medicines Inc Derivados indólicos como inhibidores de ras en el tratamiento del cáncer

Also Published As

Publication number Publication date
CN117715658A (zh) 2024-03-15
EP4346898A1 (en) 2024-04-10
TW202313631A (zh) 2023-04-01
KR20240026526A (ko) 2024-02-28
US20240277796A1 (en) 2024-08-22
AU2022281343A1 (en) 2023-11-30
WO2022251292A1 (en) 2022-12-01
JP2024521774A (ja) 2024-06-04
CA3219533A1 (en) 2022-12-01
IL308771A (en) 2024-01-01
CN118557730A (zh) 2024-08-30

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