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MX2023012554A - Vacuna universal contra la gripe. - Google Patents

Vacuna universal contra la gripe.

Info

Publication number
MX2023012554A
MX2023012554A MX2023012554A MX2023012554A MX2023012554A MX 2023012554 A MX2023012554 A MX 2023012554A MX 2023012554 A MX2023012554 A MX 2023012554A MX 2023012554 A MX2023012554 A MX 2023012554A MX 2023012554 A MX2023012554 A MX 2023012554A
Authority
MX
Mexico
Prior art keywords
influenza
neuraminidase
infection
inducing
eliciting anti
Prior art date
Application number
MX2023012554A
Other languages
English (en)
Inventor
Ben Hause
Original Assignee
Cambridge Tech Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Tech Llc filed Critical Cambridge Tech Llc
Publication of MX2023012554A publication Critical patent/MX2023012554A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5156—Animal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14023—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14041—Use of virus, viral particle or viral elements as a vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14042—Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Composiciones inmunogénicas para inducir una respuesta inmunitaria universal contra la gripe y, en particular, contra la gripe A, mediante la generación de anticuerpos anti-neuraminidasa que proporcionan protección contra la infección por gripe heteróloga. Composiciones que comprenden vectores de expresión de baculovirus recombinantes que expresan neuraminidasa en células de insecto cultivadas dispersas en un vehículo farmacéuticamente aceptable que comprende medios de cultivo de células de insecto y adyuvante opcional. Procedimientos de inducción de respuestas inmunitarias contra la gripe y, en particular, contra la gripe A, mediante la generación de anticuerpos anti-neuraminidasa en un animal huésped susceptible a la infección.
MX2023012554A 2018-12-12 2019-12-11 Vacuna universal contra la gripe. MX2023012554A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862778409P 2018-12-12 2018-12-12

Publications (1)

Publication Number Publication Date
MX2023012554A true MX2023012554A (es) 2023-11-08

Family

ID=68887227

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019014943A MX2019014943A (es) 2018-12-12 2019-12-11 Vacuna universal contra la gripe.
MX2023012554A MX2023012554A (es) 2018-12-12 2019-12-11 Vacuna universal contra la gripe.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2019014943A MX2019014943A (es) 2018-12-12 2019-12-11 Vacuna universal contra la gripe.

Country Status (6)

Country Link
US (3) US11351241B2 (es)
EP (1) EP3666286A1 (es)
JP (2) JP7107910B2 (es)
CA (1) CA3064760A1 (es)
MX (2) MX2019014943A (es)
WO (1) WO2020123757A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2019014943A (es) * 2018-12-12 2020-08-06 Cambridge Tech Llc Vacuna universal contra la gripe.

Family Cites Families (25)

* Cited by examiner, † Cited by third party
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CA2180965C (en) 1994-01-11 2010-05-11 Tom Maria Deroo Influenza vaccine
US7731972B1 (en) 2000-02-04 2010-06-08 Vlaams Interuniversitair Instituut Voor Biotechnologie Immunoprotective influenza antigen and its use in vaccination
US6103526A (en) 1998-10-08 2000-08-15 Protein Sciences Corporation Spodoptera frugiperda single cell suspension cell line in serum-free media, methods of producing and using
MXPA02012254A (es) 2000-06-23 2003-04-25 American Cyanamid Co Montaje de particulas quimericas semejantes al virus de influenza y del tipo silvestre.
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AU2007215080A1 (en) 2006-02-13 2007-08-23 Fraunhofer Usa, Inc. Influenza antigens, vaccine compositions, and related methods
US7910112B2 (en) 2006-11-06 2011-03-22 Merial Limited Feline vaccines against avian influenza
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
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FR2949344A1 (fr) 2009-04-27 2011-03-04 Novartis Ag Vaccins de protection contre la grippe
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TWI411681B (zh) 2009-08-18 2013-10-11 Nat Univ Tsing Hua 桿狀病毒表現載體與其應用
EP2498823B1 (en) 2009-11-13 2018-08-29 INSERM - Institut National de la Santé et de la Recherche Médicale Direct protein delivery with engineered microvesicles
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EP2566521A4 (en) * 2010-05-07 2013-11-27 Camas Inc IMMUNOGEN HINGE AND METHOD FOR THEIR MANUFACTURE AND USE
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US10029005B2 (en) * 2015-02-26 2018-07-24 Boehringer Ingelheim Vetmedica Gmbh Bivalent swine influenza virus vaccine
CN105457023B (zh) 2016-01-21 2019-10-08 重庆理工大学 一种预防用h9n2型流感病毒样颗粒疫苗及其制备方法
US11702464B2 (en) 2018-03-02 2023-07-18 The University Of Chicago Methods and composition for neutralization of influenza
JP7329530B2 (ja) 2018-03-28 2023-08-18 サノフィ パスツール インコーポレイテッド ノイラミニダーゼを含む広範に防御的なワクチン組成物を生成する方法
MX2019014943A (es) * 2018-12-12 2020-08-06 Cambridge Tech Llc Vacuna universal contra la gripe.

Also Published As

Publication number Publication date
JP7107910B2 (ja) 2022-07-27
US20200188505A1 (en) 2020-06-18
JP7491600B2 (ja) 2024-05-28
WO2020123757A1 (en) 2020-06-18
US20220296698A1 (en) 2022-09-22
EP3666286A1 (en) 2020-06-17
JP2022137177A (ja) 2022-09-21
US11351241B2 (en) 2022-06-07
MX2019014943A (es) 2020-08-06
US20240091336A1 (en) 2024-03-21
US12102674B2 (en) 2024-10-01
US11771756B2 (en) 2023-10-03
JP2020094054A (ja) 2020-06-18
CA3064760A1 (en) 2020-06-12

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