MX2023002337A - Composición y métodos para el tratamiento o profilaxis de coronavirus y cánceres. - Google Patents
Composición y métodos para el tratamiento o profilaxis de coronavirus y cánceres.Info
- Publication number
- MX2023002337A MX2023002337A MX2023002337A MX2023002337A MX2023002337A MX 2023002337 A MX2023002337 A MX 2023002337A MX 2023002337 A MX2023002337 A MX 2023002337A MX 2023002337 A MX2023002337 A MX 2023002337A MX 2023002337 A MX2023002337 A MX 2023002337A
- Authority
- MX
- Mexico
- Prior art keywords
- composition
- methods
- prophylaxis
- cancers
- coronavirus
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000011321 prophylaxis Methods 0.000 title abstract 2
- 241000711573 Coronaviridae Species 0.000 title 1
- 238000011282 treatment Methods 0.000 title 1
- 241001678559 COVID-19 virus Species 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 208000009956 adenocarcinoma Diseases 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000002435 cytoreductive effect Effects 0.000 abstract 1
- 206010073095 invasive ductal breast carcinoma Diseases 0.000 abstract 1
- 201000010985 invasive ductal carcinoma Diseases 0.000 abstract 1
- 230000001394 metastastic effect Effects 0.000 abstract 1
- 206010061289 metastatic neoplasm Diseases 0.000 abstract 1
- 201000011519 neuroendocrine tumor Diseases 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
- 230000004614 tumor growth Effects 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/063—Glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/21—Endodeoxyribonucleases producing 5'-phosphomonoesters (3.1.21)
- C12Y301/21001—Deoxyribonuclease I (3.1.21.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/27—Endoribonucleases producing 3'-phosphomonoesters (3.1.27)
- C12Y301/27005—Pancreatic ribonuclease (3.1.27.5)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Genetics & Genomics (AREA)
- Reproductive Health (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
En la presente se describe una composición y métodos para tratar, reducir los síntomas o profilaxis de infecciones virales, y particularmente SARS-CoV-2. La composición mejora el suministro de oxígeno a los tejidos. También se describe en la presente una composición y métodos para tratar cánceres, particularmente adenocarcinomas, adenocarcinoma ductal infiltrante, adenocarcinoma ductal metastásico y tumores neuroendocrinos. La composición inhibe el crecimiento de células tumorales y promueve la citorreducción de tumores.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063071128P | 2020-08-27 | 2020-08-27 | |
| US202063104621P | 2020-10-23 | 2020-10-23 | |
| US202063110458P | 2020-11-06 | 2020-11-06 | |
| US202063110485P | 2020-11-06 | 2020-11-06 | |
| PCT/US2021/047643 WO2022046960A1 (en) | 2020-08-27 | 2021-08-26 | Composition and methods for treatment or prophylaxis of coronavirus and cancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023002337A true MX2023002337A (es) | 2023-05-12 |
Family
ID=80353938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023002337A MX2023002337A (es) | 2020-08-27 | 2021-08-26 | Composición y métodos para el tratamiento o profilaxis de coronavirus y cánceres. |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US12343322B2 (es) |
| EP (1) | EP4204550A4 (es) |
| MX (1) | MX2023002337A (es) |
| WO (1) | WO2022046960A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025147696A1 (en) * | 2024-01-05 | 2025-07-10 | Resolve Therapeutics, Llc | Treatment of symptoms associated with sars-cov viral infection or a prior sars-cov viral infection with nuclease agents |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6172053B1 (en) | 1999-02-24 | 2001-01-09 | Ruben G. Fabunan | Injection viral treatment |
| WO2006044263A2 (en) * | 2004-10-12 | 2006-04-27 | Advanced Biotherapy, Inc. | Treatment of herpes |
| US20070128722A1 (en) * | 2005-12-05 | 2007-06-07 | Industrial Technology Research Institute | Human mesenchymal stem cells and culturing methods thereof |
| WO2014026052A1 (en) * | 2012-08-08 | 2014-02-13 | Vanderbilt University | Composition with biofilm dispersal agents |
| CA2942706C (en) | 2014-03-28 | 2020-01-14 | Tamir Biotechnology, Inc. | Rnase for use in treating or preventing viral infections |
| US20200016231A1 (en) * | 2016-12-22 | 2020-01-16 | Whiteley Corporation Pty Ltd | Biofilm disrupting composition |
| US11426405B2 (en) | 2017-12-04 | 2022-08-30 | The Brigham And Women's Hospital, Inc. | Inhibition of JAK-STAT signaling inhibits formation of neutrophil extracellular traps (NETs) |
| WO2020106709A1 (en) * | 2018-11-19 | 2020-05-28 | Gro Biosciences Inc. | Human dnase for lung disease |
-
2021
- 2021-08-26 MX MX2023002337A patent/MX2023002337A/es unknown
- 2021-08-26 US US17/412,523 patent/US12343322B2/en active Active
- 2021-08-26 EP EP21862692.7A patent/EP4204550A4/en active Pending
- 2021-08-26 WO PCT/US2021/047643 patent/WO2022046960A1/en not_active Ceased
-
2023
- 2023-04-25 US US18/306,483 patent/US12336975B2/en active Active
-
2025
- 2025-05-22 US US19/216,534 patent/US20250332136A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022046960A1 (en) | 2022-03-03 |
| US20220062219A1 (en) | 2022-03-03 |
| US12343322B2 (en) | 2025-07-01 |
| US12336975B2 (en) | 2025-06-24 |
| EP4204550A1 (en) | 2023-07-05 |
| US20250332136A1 (en) | 2025-10-30 |
| EP4204550A4 (en) | 2024-09-25 |
| US20230248685A1 (en) | 2023-08-10 |
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