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MX2023002041A - Composiciones y métodos para tratar cánceres positivos para mesotelina. - Google Patents

Composiciones y métodos para tratar cánceres positivos para mesotelina.

Info

Publication number
MX2023002041A
MX2023002041A MX2023002041A MX2023002041A MX2023002041A MX 2023002041 A MX2023002041 A MX 2023002041A MX 2023002041 A MX2023002041 A MX 2023002041A MX 2023002041 A MX2023002041 A MX 2023002041A MX 2023002041 A MX2023002041 A MX 2023002041A
Authority
MX
Mexico
Prior art keywords
methods
compositions
positive cancers
mesothelin positive
treating mesothelin
Prior art date
Application number
MX2023002041A
Other languages
English (en)
Inventor
Agnes Hamburger
Carl Alexander Kamb
Dora Toledo Warshaviak
Talar Tokatlian
Original Assignee
A2 Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A2 Biotherapeutics Inc filed Critical A2 Biotherapeutics Inc
Publication of MX2023002041A publication Critical patent/MX2023002041A/es

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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/0636—T lymphocytes
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/32—T-cell receptors [TCR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4254—Adhesion molecules, e.g. NRCAM, EpCAM or cadherins
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Abstract

La divulgación proporciona células inmunitarias que comprenden un primer receptor activador específico para mesotelina y un segundo receptor inhibidor específico para un ligando que se ha perdido en una célula cancerosa positiva para mesotelina, y métodos de fabricación y uso de las mismas para el tratamiento del cáncer.
MX2023002041A 2020-08-20 2021-08-19 Composiciones y métodos para tratar cánceres positivos para mesotelina. MX2023002041A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063068245P 2020-08-20 2020-08-20
US202063085971P 2020-09-30 2020-09-30
PCT/US2021/046751 WO2022040454A1 (en) 2020-08-20 2021-08-19 Compositions and methods for treating mesothelin positive cancers

Publications (1)

Publication Number Publication Date
MX2023002041A true MX2023002041A (es) 2023-04-27

Family

ID=80323179

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Application Number Title Priority Date Filing Date
MX2023002041A MX2023002041A (es) 2020-08-20 2021-08-19 Composiciones y métodos para tratar cánceres positivos para mesotelina.

Country Status (9)

Country Link
US (2) US11602543B2 (es)
EP (1) EP4100028A4 (es)
JP (2) JP7634653B2 (es)
KR (2) KR20250140123A (es)
AU (1) AU2021329371A1 (es)
CA (1) CA3188862A1 (es)
IL (1) IL300500A (es)
MX (1) MX2023002041A (es)
WO (1) WO2022040454A1 (es)

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JP2025503967A (ja) * 2022-01-28 2025-02-06 エー２ バイオセラピューティクス， インコーポレイテッド メソテリン陽性がんを処置するための組成物及び方法
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