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MX2022010027A - Vacuna 2019-ncov (sars-cov-2). - Google Patents

Vacuna 2019-ncov (sars-cov-2).

Info

Publication number
MX2022010027A
MX2022010027A MX2022010027A MX2022010027A MX2022010027A MX 2022010027 A MX2022010027 A MX 2022010027A MX 2022010027 A MX2022010027 A MX 2022010027A MX 2022010027 A MX2022010027 A MX 2022010027A MX 2022010027 A MX2022010027 A MX 2022010027A
Authority
MX
Mexico
Prior art keywords
ncov
spike protein
polynucleotide
optimised
cov
Prior art date
Application number
MX2022010027A
Other languages
English (en)
Inventor
Gaurav Gupta
Reinhard Glueck
Original Assignee
Vaxbio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaxbio Ltd filed Critical Vaxbio Ltd
Publication of MX2022010027A publication Critical patent/MX2022010027A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract

La presente invención se refiere a la proteína de la espícula de Coronavirus 2019-nCoV, polinucleótidos que codifican dicha proteína de la espícula, anticuerpos y vacunas para el tratamiento o prevención de la infección por 2019-nCoV. Una modalidad se refiere al polinucleótido aislado que codifica una proteína espícula de 2091-nCoV que tiene al menos el 90% de identidad con la SEQ ID No:1, o un fragmento del mismo que tiene una reactividad antigénica cruzada, común a dicha proteína espícula, en donde dicho polinucleótido esta optimizado para expresión recombinante. En una modalidad particular el polinucleótido esta optimizado par expresión en una célula huésped seleccionada de: (a) Escherichia coli; (b) levadura, preferiblemente Komagataella o Saccharomyces; y/o (c) células de mamífero, preferiblemente células humanas.
MX2022010027A 2020-02-17 2021-02-17 Vacuna 2019-ncov (sars-cov-2). MX2022010027A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2002166.3A GB2594683A (en) 2020-02-17 2020-02-17 Vaccine
PCT/GB2021/050383 WO2021165667A1 (en) 2020-02-17 2021-02-17 2019-ncov (sars-cov-2) vaccine

Publications (1)

Publication Number Publication Date
MX2022010027A true MX2022010027A (es) 2023-01-24

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MX2022010027A MX2022010027A (es) 2020-02-17 2021-02-17 Vacuna 2019-ncov (sars-cov-2).

Country Status (15)

Country Link
US (1) US20240108715A1 (es)
EP (1) EP4106808A1 (es)
JP (1) JP2023514348A (es)
KR (1) KR20230015310A (es)
CN (1) CN116056764A (es)
AR (1) AR121361A1 (es)
AU (1) AU2021223894A1 (es)
BR (1) BR112022016346A2 (es)
CA (1) CA3168153A1 (es)
CO (1) CO2022013121A2 (es)
GB (1) GB2594683A (es)
IL (1) IL295708A (es)
MX (1) MX2022010027A (es)
TW (1) TW202140519A (es)
WO (1) WO2021165667A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250114450A (ko) 2020-02-21 2025-07-29 콤바인드 테라퓨틱스, 인코포레이션 암호화 리보핵산의 기관 보호적 발현 및 조절을 위한 조성물 및 방법
US20240269261A1 (en) * 2020-03-04 2024-08-15 Premas Biotech Pvt. Ltd Expression of sars-cov proteins, nucleic acid constructs, virus like proteins (vlps) and methods relevant thereto
EP4118211A4 (en) 2020-03-13 2024-05-29 The Johns Hopkins University Selectable marker proteins, expression vectors, for the production of virus-like particles for therapeutic and prophylactic applications
CA3174215A1 (en) 2020-04-22 2021-10-28 Ugur Sahin Coronavirus vaccine
JP2023525936A (ja) * 2020-05-18 2023-06-19 康希諾（上海）生物科技有限公司 ｍＲＮＡ又はｍＲＮＡ組成物、その調製方法及び使用
CN115315442B (zh) * 2020-05-27 2024-02-13 上海济煜医药科技有限公司 Sars-cov-2抗体及其应用
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