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MX2022009778A - Polimorfos de elafibranor. - Google Patents

Polimorfos de elafibranor.

Info

Publication number
MX2022009778A
MX2022009778A MX2022009778A MX2022009778A MX2022009778A MX 2022009778 A MX2022009778 A MX 2022009778A MX 2022009778 A MX2022009778 A MX 2022009778A MX 2022009778 A MX2022009778 A MX 2022009778A MX 2022009778 A MX2022009778 A MX 2022009778A
Authority
MX
Mexico
Prior art keywords
elafibranor
polymorphs
relates
present
crystalline forms
Prior art date
Application number
MX2022009778A
Other languages
English (en)
Inventor
Karine Bertrand
Jean- François DELHOMEL
Alice Roudot
Original Assignee
Genfit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genfit filed Critical Genfit
Publication of MX2022009778A publication Critical patent/MX2022009778A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a formas cristalinas novedosas de elafibranor.
MX2022009778A 2020-02-10 2021-02-04 Polimorfos de elafibranor. MX2022009778A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2020053359 2020-02-10
PCT/EP2021/052713 WO2021160520A1 (en) 2020-02-10 2021-02-04 Polymorphs of elafibranor

Publications (1)

Publication Number Publication Date
MX2022009778A true MX2022009778A (es) 2022-09-09

Family

ID=69591622

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022009778A MX2022009778A (es) 2020-02-10 2021-02-04 Polimorfos de elafibranor.

Country Status (11)

Country Link
US (1) US20230094109A1 (es)
EP (1) EP4103546A1 (es)
JP (2) JP2023513712A (es)
KR (1) KR20220140760A (es)
CN (1) CN115003653A (es)
AU (1) AU2021219286A1 (es)
BR (1) BR112022015807A2 (es)
CA (1) CA3163583A1 (es)
IL (1) IL294503A (es)
MX (1) MX2022009778A (es)
WO (1) WO2021160520A1 (es)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2841900B1 (fr) * 2002-07-08 2007-03-02 Genfit S A Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations
FR2841784B1 (fr) 2002-07-08 2007-03-02 Composition a base de derives de 1,3-diphenylprop-2en-1-one substitues, preparation et utilisations
AU2010323066B2 (en) 2009-11-26 2014-12-11 Genfit Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
PT2571843T (pt) * 2010-05-17 2018-01-29 Genfit Preparação melhorada de derivados de calcona
CA2897258C (en) 2013-01-18 2021-02-02 Genfit Methods of treatment of fibrosis and cancers
WO2017167935A1 (en) * 2016-03-31 2017-10-05 Genfit Methods of treatment of cholestatic diseases
CA3051146A1 (en) * 2017-01-22 2018-07-26 Crystal Pharmaceutical (Suzhou) Co., Ltd. Crystal form of gft-505 and preparation method and use thereof
WO2019099761A1 (en) * 2017-11-16 2019-05-23 Teva Pharmaceuticals International Gmbh Solid state forms of elafibranor
WO2019186410A1 (en) * 2018-03-27 2019-10-03 Lupin Limited Solid forms of elafibranor and processes thereof
WO2020039297A1 (en) * 2018-08-24 2020-02-27 Mankind Pharma Ltd. Novel compounds and their use in preparation of elafibranor and pharmaceutical acceptable salts thereof

Also Published As

Publication number Publication date
WO2021160520A1 (en) 2021-08-19
JP2025146849A (ja) 2025-10-03
IL294503A (en) 2022-09-01
AU2021219286A1 (en) 2022-09-22
JP2023513712A (ja) 2023-04-03
KR20220140760A (ko) 2022-10-18
CN115003653A (zh) 2022-09-02
EP4103546A1 (en) 2022-12-21
US20230094109A1 (en) 2023-03-30
BR112022015807A2 (pt) 2023-03-14
CA3163583A1 (en) 2021-08-19

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