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MX2022004767A - (+)-cis tetrahidrocannabinol ((+)-cis-thc) para uso como medicamento. - Google Patents

(+)-cis tetrahidrocannabinol ((+)-cis-thc) para uso como medicamento.

Info

Publication number
MX2022004767A
MX2022004767A MX2022004767A MX2022004767A MX2022004767A MX 2022004767 A MX2022004767 A MX 2022004767A MX 2022004767 A MX2022004767 A MX 2022004767A MX 2022004767 A MX2022004767 A MX 2022004767A MX 2022004767 A MX2022004767 A MX 2022004767A
Authority
MX
Mexico
Prior art keywords
thc
cannabinoid
cis
tetrahydrocannabinol
medicament
Prior art date
Application number
MX2022004767A
Other languages
English (en)
Inventor
Geoffrey Guy
Benjamin Whalley
Volker Knappertz
Marie Woolley-Roberts
Original Assignee
Gw Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gw Res Ltd filed Critical Gw Res Ltd
Publication of MX2022004767A publication Critical patent/MX2022004767A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/348—Cannabaceae
    • A61K36/3482—Cannabis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La presente invención se refiere a un compuesto cannabinoide de tipo tetrahidrocannabinol (THC) para uso como medicamento. El cannabinoide de tipo THC es un enantiómero del (-)-trans-tetrahidrocannabinol, que es un cannabinoide natural que se puede encontrar en las cepas de plantas de cannabis que han sido criadas para producir THC como cannabinoide dominante. Se ha descubierto que el enantiómero particular (+)-cis tetrahidrocannabinol tiene propiedades que son diferentes del (-)-trans-THC que ocurre de forma natural. Se ha descubierto que el cannabinoide (+)-cis-THC se encuentra en bajas concentraciones en determinadas cepas de plantas de cannabis que se han criado para producir cannabidiol (CBD) como cannabinoide dominante. Además, el cannabinoide se puede producir por medios sintéticos.
MX2022004767A 2019-10-25 2020-10-23 (+)-cis tetrahidrocannabinol ((+)-cis-thc) para uso como medicamento. MX2022004767A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1915514.2A GB2588456B (en) 2019-10-25 2019-10-25 Cannabinoid compound
PCT/GB2020/052679 WO2021079136A1 (en) 2019-10-25 2020-10-23 (+)-cis tetrahydrocannabinol ((+)-cis-thc) for use as a medicament

Publications (1)

Publication Number Publication Date
MX2022004767A true MX2022004767A (es) 2022-05-16

Family

ID=68769052

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022004767A MX2022004767A (es) 2019-10-25 2020-10-23 (+)-cis tetrahidrocannabinol ((+)-cis-thc) para uso como medicamento.

Country Status (11)

Country Link
US (1) US20220387377A1 (es)
EP (1) EP4048254A1 (es)
JP (1) JP7671748B2 (es)
KR (1) KR20220097425A (es)
CN (1) CN114828843A (es)
AU (1) AU2020371267A1 (es)
CA (1) CA3155390A1 (es)
GB (1) GB2588456B (es)
MX (1) MX2022004767A (es)
TW (1) TW202128146A (es)
WO (1) WO2021079136A1 (es)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10051427C1 (de) * 2000-10-17 2002-06-13 Adam Mueller Verfahren zur Herstellung eines Tetrahydrocannabinol- und Cannabidiol-haltigen Extraktes aus Cannabis-Pflanzenmaterial sowie Cannabis-Extrakte
TWI369203B (en) * 2004-11-22 2012-08-01 Euro Celtique Sa Methods for purifying trans-(-)-△9-tetrahydrocannabinol and trans-(+)-△9-tetrahydrocannabinol
TWI366460B (en) * 2005-06-16 2012-06-21 Euro Celtique Sa Cannabinoid active pharmaceutical ingredient for improved dosage forms
ES2547354T3 (es) * 2013-09-03 2015-10-05 Symrise Ag Mezclas de compuestos cannabinoides, su preparación y uso
GB2531282A (en) * 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabinoids in the treatment of epilepsy
CN109476625A (zh) * 2016-06-16 2019-03-15 蒂温诺特技术有限公司 用于制备大麻素前药的方法、药物制剂及其用途
WO2018057596A1 (en) * 2016-09-21 2018-03-29 JC Pharma, Inc. Method and composition for acute treatment of seizures
US10640482B2 (en) * 2017-07-21 2020-05-05 University Of South Florida Synthesis of cannabinoids
US10307392B2 (en) * 2017-10-21 2019-06-04 Alexander Kariman Compound and method for treatment of diseases and disorders
US10751380B2 (en) * 2018-03-08 2020-08-25 Alexander Kariman Compound and method for treating spasms, inflammation and pain
WO2019180706A1 (en) * 2018-03-19 2019-09-26 Bol Pharma Ltd. Methods and compositions for treating epilepsy and associated disorders
GB201806953D0 (en) * 2018-04-27 2018-06-13 Gw Res Ltd Cannabidiol Preparations

Also Published As

Publication number Publication date
EP4048254A1 (en) 2022-08-31
GB2588456B (en) 2023-02-01
WO2021079136A1 (en) 2021-04-29
TW202128146A (zh) 2021-08-01
KR20220097425A (ko) 2022-07-07
AU2020371267A1 (en) 2022-05-19
CA3155390A1 (en) 2021-04-29
US20220387377A1 (en) 2022-12-08
GB2588456A (en) 2021-04-28
GB201915514D0 (en) 2019-12-11
JP7671748B2 (ja) 2025-05-02
JP2022553556A (ja) 2022-12-23
CN114828843A (zh) 2022-07-29

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