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MX2022001767A - Construcciones de vesículas-oligonucleótidos antisentido (aso) extracelulares que se dirigen a transductor de señal y activador de la transcripción 6 (stat6). - Google Patents

Construcciones de vesículas-oligonucleótidos antisentido (aso) extracelulares que se dirigen a transductor de señal y activador de la transcripción 6 (stat6).

Info

Publication number
MX2022001767A
MX2022001767A MX2022001767A MX2022001767A MX2022001767A MX 2022001767 A MX2022001767 A MX 2022001767A MX 2022001767 A MX2022001767 A MX 2022001767A MX 2022001767 A MX2022001767 A MX 2022001767A MX 2022001767 A MX2022001767 A MX 2022001767A
Authority
MX
Mexico
Prior art keywords
aso
stat6
extracellular vesicle
constructs targeting
exosomes
Prior art date
Application number
MX2022001767A
Other languages
English (en)
Inventor
Sriram Sathyanarayanan
Ajay Verma
Dalia Burzyn
Sushrut Kamerkar
Adam T Boutin
Wendy Broom
Original Assignee
Codiak Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codiak Biosciences Inc filed Critical Codiak Biosciences Inc
Publication of MX2022001767A publication Critical patent/MX2022001767A/es

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Abstract

La presente descripción se refiere a vesículas extracelulares, por ejemplo, exosomas, que comprenden un oligonucleótido antisentido (ASO), en donde el ASO comprende una secuencia de nucleótidos contiguos de 10 a 30 nucleótidos de longitud que es complementaria a una secuencia de ácidos nucleicos dentro de una transcripción de STAT6. En la presente también se proporcionan métodos para producir los exosomas y métodos para usar los exosomas para tratar y/o prevenir enfermedades o trastornos.
MX2022001767A 2019-08-14 2020-08-14 Construcciones de vesículas-oligonucleótidos antisentido (aso) extracelulares que se dirigen a transductor de señal y activador de la transcripción 6 (stat6). MX2022001767A (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962886944P 2019-08-14 2019-08-14
US201962900138P 2019-09-13 2019-09-13
US201962903518P 2019-09-20 2019-09-20
US201962936216P 2019-11-15 2019-11-15
US202062989477P 2020-03-13 2020-03-13
US202063035392P 2020-06-05 2020-06-05
PCT/US2020/046559 WO2021030776A1 (en) 2019-08-14 2020-08-14 Extracellular vesicle-aso constructs targeting stat6

Publications (1)

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MX2022001767A true MX2022001767A (es) 2022-06-09

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US (2) US20250115904A1 (es)
EP (2) EP4470619A3 (es)
JP (1) JP2022544289A (es)
KR (1) KR20220070433A (es)
CN (1) CN114729356A (es)
AU (1) AU2020328611A1 (es)
BR (1) BR112022002691A2 (es)
CA (1) CA3147680A1 (es)
IL (1) IL290499A (es)
MX (1) MX2022001767A (es)
WO (1) WO2021030776A1 (es)

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