[go: up one dir, main page]

MX2019008288A - Composicion farmaceutica de disgregacion rapida. - Google Patents

Composicion farmaceutica de disgregacion rapida.

Info

Publication number
MX2019008288A
MX2019008288A MX2019008288A MX2019008288A MX2019008288A MX 2019008288 A MX2019008288 A MX 2019008288A MX 2019008288 A MX2019008288 A MX 2019008288A MX 2019008288 A MX2019008288 A MX 2019008288A MX 2019008288 A MX2019008288 A MX 2019008288A
Authority
MX
Mexico
Prior art keywords
pharmaceutical composition
disgregation
rapid
matrix network
open matrix
Prior art date
Application number
MX2019008288A
Other languages
English (en)
Other versions
MX383146B (es
Inventor
Ahuja Varinder
Plaksin Daniel
Sonavane Ganeshchandra
Lokhande Parag
Kantilal Jain Devendra
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Publication of MX2019008288A publication Critical patent/MX2019008288A/es
Publication of MX383146B publication Critical patent/MX383146B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se dirige a una composición farmacéutica, que comprende una red de matriz abierta que incorpora uno o más ingredientes farmacéuticamente activos, en la que la red de matriz abierta comprende maltodextrina y ácido hialurónico o una sal farmacéuticamente aceptable de la misma.
MX2019008288A 2017-01-11 2018-01-11 Composición farmacéutica de disgregación rápida. MX383146B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201711001145 2017-01-11
PCT/EP2018/050635 WO2018130603A1 (en) 2017-01-11 2018-01-11 A fast disintegrating pharmaceutical composition

Publications (2)

Publication Number Publication Date
MX2019008288A true MX2019008288A (es) 2019-09-16
MX383146B MX383146B (es) 2025-03-13

Family

ID=61054345

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019008288A MX383146B (es) 2017-01-11 2018-01-11 Composición farmacéutica de disgregación rápida.

Country Status (14)

Country Link
US (1) US10952959B2 (es)
EP (1) EP3568124A1 (es)
JP (1) JP7042275B2 (es)
KR (1) KR20190104322A (es)
CN (1) CN110049757A (es)
AU (1) AU2018208531A1 (es)
BR (1) BR112019010949A2 (es)
CA (1) CA3046725A1 (es)
MX (1) MX383146B (es)
MY (1) MY195591A (es)
PH (1) PH12019501260A1 (es)
RU (1) RU2751193C2 (es)
WO (1) WO2018130603A1 (es)
ZA (1) ZA201904087B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230346695A1 (en) 2020-09-29 2023-11-02 Millicent Pharma Limited Orodispersible formulations

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4780414A (en) 1985-01-18 1988-10-25 Bio-Technology General Corp. Method of producing high molecular weight sodium hyallronate by fermentation of streptococcus
GB9908014D0 (en) 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions
US20080138399A1 (en) 1999-07-16 2008-06-12 Aradigm Corporation Dual release nicotine formulations, and systems and methods for their use
US6761904B2 (en) 2000-03-31 2004-07-13 Nycomed Austria Gmbh Pharmaceutical kit comprising midodrine as active drug substance
WO2002002081A1 (en) 2000-07-05 2002-01-10 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and methods of using same
CA2417736A1 (en) 2000-07-19 2002-01-24 Lavipharm Laboratories, Inc. Sildenafil citrate solid dispersions having high water solubility
US6509040B1 (en) 2001-06-22 2003-01-21 R.P. Scherer Corporation Fast dispersing dosage forms essentially free of mammalian gelatin
US20030118653A1 (en) 2001-07-06 2003-06-26 Lavipharm Laboratories Inc. Quick dissolving oral mucosal drug delivery device with moisture barrier coating
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
CA2484724C (en) 2002-05-07 2007-01-16 Ferring B.V. Pharmaceutical formulations
US9561182B2 (en) 2003-08-22 2017-02-07 Cure Pharmaceutical Corporation Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals
WO2004056343A1 (en) 2002-12-19 2004-07-08 Polymorfix, Inc. Ingestible formulations for transient, noninvasive reduction of gastric volume
US8012505B2 (en) * 2003-02-28 2011-09-06 Alk-Abello A/S Dosage form having a saccharide matrix
US20050074489A1 (en) 2003-10-01 2005-04-07 Pediamed Pharmaceuticals, Inc. Effervescent and effervescent-dispersion compositions for medicaments and methods of use thereof
EP2322198A2 (en) * 2003-11-10 2011-05-18 Reprise Biopharmaceutics, LLC Pharmaceutical compositions including low dosages of desmopressin
US20050136112A1 (en) 2003-12-19 2005-06-23 Pediamed Pharmaceuticals, Inc. Oral medicament delivery system
CA2552221A1 (en) 2003-12-31 2005-07-21 Actavis Group Hf Donepezil formulations
US20050191349A1 (en) 2003-12-31 2005-09-01 Garth Boehm Galantamine formulations
CN100366294C (zh) 2004-04-30 2008-02-06 量子高科（北京）研究院有限公司 一种口腔速溶制剂及其生产方法
US20060292099A1 (en) 2005-05-25 2006-12-28 Michael Milburn Treatment of eye disorders with sirtuin modulators
EP1891937A1 (en) 2006-08-25 2008-02-27 Novartis AG Galenic formulations of aliskiren
EP2489338B1 (en) * 2006-08-28 2014-05-14 Rexaderm, INC. Dry wound dressing and drug delivery system
WO2008065144A2 (en) 2006-11-29 2008-06-05 Novartis Ag Galenic formulations of organic compounds
US8900629B2 (en) 2007-04-05 2014-12-02 University Of Kansas Rapidly dissolving pharmaceutical compositions comprising pullulan
KR100937625B1 (ko) 2007-08-10 2010-01-20 주식회사 제닉 가용성 웹 공극필름 및 이의 제조방법
US20090047330A1 (en) 2007-08-17 2009-02-19 Ramesh Bangalore Oral fast dissolving films for erectile dysfunction bioactive agents
US20090047350A1 (en) 2007-08-17 2009-02-19 Ramesh Bangalore Perforated water soluble polymer based edible films
US20090060993A1 (en) 2007-09-04 2009-03-05 Joseph Schwarz Solid pharmaceutical composition for enhanced delivery of coenzyme q-10 and ubiquinones
EP2209814B1 (en) 2007-11-13 2017-01-25 Bio-Technology General (Israel) Ltd. Dilute filtration sterilization process for viscoelastic biopolymers
PE20091084A1 (es) 2007-12-07 2009-07-23 Schering Plough Healthcare Formulaciones farmaceuticas de fenilefrina y composiciones para absorcion transmucosal
US20120076858A1 (en) 2009-06-04 2012-03-29 Basf Se Orally Disintegrating Dosage Forms Containing Taste-Masked Active Ingredients
US8431122B2 (en) 2009-07-02 2013-04-30 Oxthera Intellectual Property Ab Purification and isolation of recombinant oxalate degrading enzymes and spray-dried particles containing oxalate degrading enzymes
KR101138258B1 (ko) * 2009-12-09 2012-04-24 (주)바이오제닉스 올리고머 복합체의 형성을 통한 난/불용성 활성물질의 가용화 방법
US10548839B2 (en) 2010-03-16 2020-02-04 Wei Tian Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form
JO3112B1 (ar) 2010-03-29 2017-09-20 Ferring Bv تركيبة دوائية سريعة التحلل
CA2793485A1 (en) * 2010-03-29 2011-10-06 Ferring B.V. A fast dissolving pharmaceutical composition
ES2527679T5 (es) 2010-06-24 2022-04-19 Procter & Gamble Artículos solubles de dosis unitaria que comprenden un polímero catiónico
US20130039981A1 (en) 2011-07-28 2013-02-14 Subraman Rao Cherurkuri Quick Dissolving, Long Acting Zinc Therapeutic Formulations
US9731018B2 (en) 2011-09-16 2017-08-15 Ferring B.V. Fast dissolving pharmaceutical composition
US20130101636A1 (en) 2011-10-12 2013-04-25 Kevin W. Lang Dietary supplements with rapid buccal dissolution
CA2853823C (en) 2011-10-28 2016-12-20 Integritybio Inc. Protein formulations containing amino acids
WO2013136346A2 (en) 2012-03-15 2013-09-19 Katakam Venkatesh Taste masking pharmaceutical orally dissolving strips of lornoxicam
US20140005304A1 (en) * 2012-07-02 2014-01-02 Baker Hughes Incorporated Nanocomposite and method of making the same
EP2895147B1 (en) 2012-09-11 2019-06-26 University Of The Witwatersrand, Johannesburg Rapidly dissolving pharmaceutical composition
US8840425B2 (en) * 2012-09-19 2014-09-23 Yfc-Boneagle Electric Co., Ltd. Connector apparatus and adapter apparatus with indication function
EP2906208B1 (en) 2012-10-09 2019-01-30 Sears, Douglas Therapeutic treatment
TW201422254A (zh) * 2012-11-21 2014-06-16 Ferring Bv 用於速釋及延釋的組成物
WO2014093850A1 (en) 2012-12-13 2014-06-19 Robert Davidson Mouthguard for the delivery of active ingredients
MX2013001278A (es) 2013-01-31 2014-07-30 Miguel Ángel García Pérez Composicion farmaceutica con un sistema bifasico de liberacion inmediata para el control de eventos convulsivos y del dolor.
US20140271923A1 (en) 2013-03-14 2014-09-18 Christopher Brian Reid Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions
CN103211801B (zh) 2013-04-02 2016-02-03 苏州人本药业有限公司 一种在口腔中快速溶解的膜剂及其制备方法
WO2014166994A1 (en) 2013-04-09 2014-10-16 Danmarks Tekniske Universitet Nano-microdelivery systems for oral delivery of an active ingredient
HK1225624A1 (zh) 2013-07-31 2017-09-15 Bluepharma - Industria Farmaceutica, S.A. 口腔可分散膜
WO2015155307A1 (en) 2014-04-11 2015-10-15 Sanovel Ilac Sanayi Ve Ticaret A.S. Pharmaceutical combinations of rivaroxaban and proton pump inhibitors
CN104000800A (zh) 2014-04-28 2014-08-27 万特制药(海南)有限公司 马来酸阿塞那平口腔速溶膜剂及其制备方法
WO2015169957A1 (en) 2014-05-09 2015-11-12 Sanovel Ilac Sanayi Ve Ticaret A.S. Pharmaceutical combinations of rivaroxaban and h2-receptor antagonists
KR101664106B1 (ko) 2014-09-11 2016-10-10 한국화학연구원 폴리믹신 b 화합물을 포함하는 심혈관 질환의 예방 및 치료용 약학적 조성물
CN104523657A (zh) 2014-12-26 2015-04-22 万特制药(海南)有限公司 苯磺酸氨氯地平口腔速溶膜及其制备方法
CN104958279A (zh) 2015-06-27 2015-10-07 万特制药(海南)有限公司 氯雷他定口腔速溶膜及其制备方法
CN105663096B (zh) * 2016-01-25 2019-06-14 南京济群医药科技股份有限公司 一种沃诺拉赞口腔速溶膜剂及其制备方法

Also Published As

Publication number Publication date
RU2019121790A (ru) 2021-02-12
BR112019010949A2 (pt) 2019-10-01
RU2751193C2 (ru) 2021-07-12
AU2018208531A1 (en) 2019-06-13
KR20190104322A (ko) 2019-09-09
JP2020503305A (ja) 2020-01-30
RU2019121790A3 (es) 2021-02-15
JP7042275B2 (ja) 2022-03-25
PH12019501260A1 (en) 2020-01-20
ZA201904087B (en) 2022-01-26
US20190358156A1 (en) 2019-11-28
CA3046725A1 (en) 2018-07-19
MY195591A (en) 2023-02-02
US10952959B2 (en) 2021-03-23
EP3568124A1 (en) 2019-11-20
CN110049757A (zh) 2019-07-23
MX383146B (es) 2025-03-13
WO2018130603A1 (en) 2018-07-19

Similar Documents

Publication Publication Date Title
PH12019502058A1 (en) Farnesoid x receptor agonists and uses thereof
PH12018500586B1 (en) Farnesoid x receptor agonists and uses thereof
MX2024000362A (es) Composiciones y metodos para fabricar microparticulas de proteina.
MX389178B (es) Formulacion de proporcion fija de insulina glargina/lixisenatida.
MX2017003561A (es) Composiciones y metodos para revestimientos cannabinoides para su uso en la administracion de farmacos.
IL253619B (en) Encapsulation of high potency active agents
MX382580B (es) Formulaciones de liberación inmediata disuasivas de abuso que comprenden polisacáridos no celulósicos.
MX2017014994A (es) Formulacion solida oral que contiene irinotecano y metodo de preparacion de la misma.
MX387731B (es) Composiciones farmacéuticas orales de mesalazina.
MX381792B (es) Agente terapéutico para la fibrosis.
MX385447B (es) Agente antihipertensivo
GEP20237486B (en) Formulations of copanlisib
EA202090913A1 (ru) Композиция таблеток с модифицированным высвобождением, содержащая мирабегрон
PH12018501758A1 (en) Oritavancin formulations
MX2019008288A (es) Composicion farmaceutica de disgregacion rapida.
BR112021021841A2 (pt) Formulação de pó para administração intranasal, e método de fabricação da mesma
ITUA20164387A1 (it) Composizione farmaceutica comprendente Cetraria islandica Ach., sodio ialuronato e una soluzione salina per il trattamento di affezioni dell'apparato respiratorio.
UY36273A (es) Composicion para el tratamiento de neuropatías y del dolor neuropático
MX2019015869A (es) Nuevas formulaciones orales de belinostat.
EA201992844A1 (ru) Новые пероральные составы на основе белиностата
MX2019009909A (es) Composiciones farmaceuticas para terapia de combinacion.
EA201891848A1 (ru) Фармацевтическая композиция для применения в лечении фиброза
MX393608B (es) Profilactico o agente terapeutico para queratitis fungica.
BR112017014295A2 (pt) composição farmacêutica.
EA202091403A1 (ru) Производные 2-оксо-1-пирролидинилимидазотиадиазола