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MX2019008158A - Terapia de combinacion para el tratamiento del cancer. - Google Patents

Terapia de combinacion para el tratamiento del cancer.

Info

Publication number
MX2019008158A
MX2019008158A MX2019008158A MX2019008158A MX2019008158A MX 2019008158 A MX2019008158 A MX 2019008158A MX 2019008158 A MX2019008158 A MX 2019008158A MX 2019008158 A MX2019008158 A MX 2019008158A MX 2019008158 A MX2019008158 A MX 2019008158A
Authority
MX
Mexico
Prior art keywords
cancer
treatment
combination therapy
formula
cdk4
Prior art date
Application number
MX2019008158A
Other languages
English (en)
Inventor
C Strum Jay
Xiong Rui
R Thatcher Gregory
zhao Jiong
A Tonetti Debra
Original Assignee
G1 Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by G1 Therapeutics Inc filed Critical G1 Therapeutics Inc
Publication of MX2019008158A publication Critical patent/MX2019008158A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Las composiciones, combinaciones y métodos que comprenden la administración de un inhibidor de CDK4/6 de Formula D con un regulador descendente selectivo de receptor de estrógenos de Formula A, B o C que son ventajosos para el tratamiento de la proliferación celular anormal, que incluye un cáncer o un tumor.
MX2019008158A 2017-01-06 2018-01-05 Terapia de combinacion para el tratamiento del cancer. MX2019008158A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762443588P 2017-01-06 2017-01-06
PCT/US2018/012675 WO2018129387A1 (en) 2017-01-06 2018-01-05 Combination therapy for the treatment of cancer

Publications (1)

Publication Number Publication Date
MX2019008158A true MX2019008158A (es) 2019-12-09

Family

ID=62791140

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019008158A MX2019008158A (es) 2017-01-06 2018-01-05 Terapia de combinacion para el tratamiento del cancer.

Country Status (15)

Country Link
US (1) US11364222B2 (es)
EP (1) EP3565558B1 (es)
JP (1) JP7229162B2 (es)
KR (1) KR102576011B1 (es)
CN (1) CN110177554B (es)
AR (1) AR110728A1 (es)
AU (2) AU2018205262A1 (es)
CA (1) CA3048057A1 (es)
EA (1) EA201991622A1 (es)
IL (1) IL267795B2 (es)
MX (1) MX2019008158A (es)
NZ (1) NZ754865A (es)
TW (1) TWI823845B (es)
WO (1) WO2018129387A1 (es)
ZA (1) ZA201904188B (es)

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US10695333B2 (en) 2017-12-01 2020-06-30 Novartis Ag Pharmaceutical combination comprising LSZ102 and alpelisib
RS63876B1 (sr) * 2018-07-12 2023-02-28 Lilly Co Eli Selektivni degradatori estrogenskih receptora
EP3837548A2 (en) 2018-08-17 2021-06-23 F. Hoffmann-La Roche AG Diagnostic and therapeutic methods for the treatment of breast cancer
WO2020097625A1 (en) * 2018-11-09 2020-05-14 G1 Therapeutics, Inc. Therapeutic regimens for treatment of cancer using eribulin and selective cdk4/6 inhibitor combinations
US20220293213A1 (en) * 2019-09-02 2022-09-15 Phil Rivers Technology, Ltd. Method for acquiring intracellular deterministic events and electronic apparatus
EP4096686A4 (en) * 2020-01-27 2024-01-10 Isola Therapeutics, Inc. TISSUE DOSAGE FOR LOCAL INTRALUMINAL DRUG ADMINISTRATION
ES3048084T3 (en) 2020-05-19 2025-12-09 Pharmacosmos Holding As Cyclin-dependent kinase inhibiting compounds for the treatment of medical disorders
US10988479B1 (en) 2020-06-15 2021-04-27 G1 Therapeutics, Inc. Morphic forms of trilaciclib and methods of manufacture thereof
WO2022199656A1 (zh) * 2021-03-24 2022-09-29 贝达药业股份有限公司 药物组合、包含其的试剂盒及其用途

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