MX2019006767A - Solucion de conservacion de acido nucleico y metodos de elaboracion y uso. - Google Patents
Solucion de conservacion de acido nucleico y metodos de elaboracion y uso.Info
- Publication number
- MX2019006767A MX2019006767A MX2019006767A MX2019006767A MX2019006767A MX 2019006767 A MX2019006767 A MX 2019006767A MX 2019006767 A MX2019006767 A MX 2019006767A MX 2019006767 A MX2019006767 A MX 2019006767A MX 2019006767 A MX2019006767 A MX 2019006767A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- nucleic acid
- biological sample
- compositions
- manufacture
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 239000003761 preservation solution Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 6
- 239000012472 biological sample Substances 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 abstract 1
- YUJLIIRMIAGMCQ-CIUDSAMLSA-N Ser-Leu-Ser Chemical compound [H]N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(O)=O YUJLIIRMIAGMCQ-CIUDSAMLSA-N 0.000 abstract 1
- 239000007983 Tris buffer Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- JIWBIWFOSCKQMA-LTKCOYKYSA-N all-cis-octadeca-6,9,12,15-tetraenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/CCCCC(O)=O JIWBIWFOSCKQMA-LTKCOYKYSA-N 0.000 abstract 1
- 239000006172 buffering agent Substances 0.000 abstract 1
- 230000003196 chaotropic effect Effects 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003172 expectorant agent Substances 0.000 abstract 1
- ZJYYHGLJYGJLLN-UHFFFAOYSA-N guanidinium thiocyanate Chemical compound SC#N.NC(N)=N ZJYYHGLJYGJLLN-UHFFFAOYSA-N 0.000 abstract 1
- 229940066491 mucolytics Drugs 0.000 abstract 1
- 238000004321 preservation Methods 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 229940098465 tincture Drugs 0.000 abstract 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 abstract 1
- 230000000007 visual effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
Abstract
Se describen composiciones de conservación de ácido nucleico y métodos de elaboración y usos de estas. Las composiciones incluyen un portador, un agente caotrópico, un agente amortiguador, un agente quelante, un tensioactivo, un alcohol, un ácido, y un agente mucolítico. Las composiciones como soluciones acuosas pueden incluir agua como un portador. Las formas de realización preferidas incluyen agua, tiocianato de guanidina, Tris, EDTA, SLS, SDA 3C, HCI y N-acetil-L-cisteína. Algunas formas de realización incluyen una tintura coloreada como un indicador visual. Los métodos de elaboración incluyen combinar los componentes en una mezcla, tal como una solución acuosa. Los métodos de uso incluyen proporcionar una muestra biológica que incluya ácido nucleico y poner en contacto la muestra biológica con la composición. Los kits incluyen la composición dispuesta en una parte de un aparato de recolección de muestras biológicas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762446818P | 2017-01-16 | 2017-01-16 | |
| PCT/US2018/013862 WO2018132827A1 (en) | 2017-01-16 | 2018-01-16 | Nucleic acid preservation solution and methods of manufacture and use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019006767A true MX2019006767A (es) | 2019-08-22 |
| MX374141B MX374141B (es) | 2025-03-05 |
Family
ID=62839045
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019006767A MX374141B (es) | 2017-01-16 | 2018-01-16 | Solucion de conservacion de acido nucleico y metodos de elaboracion y uso. |
| MX2020003996A MX2020003996A (es) | 2017-01-16 | 2019-06-10 | Solucion de conservacion de acido nucleico y metodos de elaboracion y uso. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020003996A MX2020003996A (es) | 2017-01-16 | 2019-06-10 | Solucion de conservacion de acido nucleico y metodos de elaboracion y uso. |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US10174362B2 (es) |
| EP (3) | EP4372099A3 (es) |
| JP (4) | JP6652692B2 (es) |
| CN (2) | CN110072999B (es) |
| CA (1) | CA3042088A1 (es) |
| CY (1) | CY1126046T1 (es) |
| DK (1) | DK3568475T3 (es) |
| ES (1) | ES2942577T3 (es) |
| FI (1) | FI3568475T3 (es) |
| HR (1) | HRP20230345T1 (es) |
| HU (1) | HUE062204T2 (es) |
| LT (1) | LT3568475T (es) |
| MX (2) | MX374141B (es) |
| PL (1) | PL3568475T3 (es) |
| PT (1) | PT3568475T (es) |
| SI (1) | SI3568475T1 (es) |
| WO (1) | WO2018132827A1 (es) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3568475T1 (sl) * | 2017-01-16 | 2023-05-31 | Spectrum Solutions L. L. C. | Raztopina za ohranjanje nukleinske kisline in načini uporabe |
| CN113272314A (zh) * | 2018-11-14 | 2021-08-17 | 光谱解决方案有限责任公司 | Rna保存溶液及制造方法和使用方法 |
| MX2021005918A (es) | 2018-11-20 | 2021-08-24 | Spectrum Solutions Llc | Sistema de recoleccion de muestras que incluye una tapa de sellado y valvula. |
| US11701094B2 (en) | 2019-06-20 | 2023-07-18 | Spectrum Solutions L.L.C. | Sample collection system including valve and plug assemblies |
| US20220333156A1 (en) * | 2019-09-18 | 2022-10-20 | Technosuruga Laboratory Co., Ltd. | Sample preservation solution, and analysis device and analysis method using the same |
| CN110747193B (zh) * | 2019-09-25 | 2021-08-31 | 广州市达瑞生物技术股份有限公司 | 一种基于二代测序平台的肺癌多基因联合检测试剂盒质控品 |
| CN110643679A (zh) * | 2019-09-26 | 2020-01-03 | 李润成 | 一种水环境dna采集保存卡及其制作方法 |
| CN113133996B (zh) * | 2020-01-20 | 2023-07-04 | 山东威高宏瑞医学科技有限公司 | 乙酰半胱氨酸或其化学上可接受的盐/酯在制备结缔组织的分离制剂中的应用 |
| CN111172239A (zh) * | 2020-02-28 | 2020-05-19 | 上海思路迪医学检验所有限公司 | 一种病毒样本保存液、核酸提取试剂及病毒核酸提取方法 |
| WO2021205470A1 (en) * | 2020-04-06 | 2021-10-14 | 30M Genomics Private Limited | Buffer composition for one step nucleic acid sample preparation and storage from biological samples |
| JP2023521803A (ja) * | 2020-04-14 | 2023-05-25 | スペクトラム・ソリューションズ・エルエルシー | ウイルス核酸の検出用製品及びその検出方法 |
| CN111218444B (zh) * | 2020-04-24 | 2020-09-01 | 广州安必平医药科技股份有限公司 | 一种痰液保存液 |
| CN111690640B (zh) * | 2020-06-22 | 2023-10-03 | 广州东盛生物科技有限公司 | 一种高度兼容磁珠法病毒核酸提取试剂盒的病毒保存液 |
| CN112280775A (zh) * | 2020-08-10 | 2021-01-29 | 广州捷倍斯生物科技有限公司 | 一种生物样品核酸保护液及应用 |
| US20230332132A1 (en) * | 2020-08-28 | 2023-10-19 | Kao Corporation | Rna storage method |
| CN112029824A (zh) * | 2020-09-15 | 2020-12-04 | 北京康美天鸿生物科技有限公司 | 一种通用于多种样本的核酸保存液 |
| JP2023549013A (ja) * | 2020-09-18 | 2023-11-22 | プロコムキュア バイオテック ゲーエムベーハー | 唾液サンプル採取用キット |
| AT18096U1 (de) * | 2020-09-18 | 2024-01-15 | Procomcure Biotech Gmbh | Kit zur Entnahme von Speichelproben |
| CN112176025B (zh) * | 2020-10-12 | 2022-05-24 | 广东南芯医疗科技有限公司 | 一种核酸保存液及其制备方法和应用 |
| CN114369646A (zh) * | 2020-10-15 | 2022-04-19 | 中国疾病预防控制中心 | 一种痰液液化方法及其专用液化试剂 |
| CN112760318B (zh) * | 2020-12-30 | 2023-11-17 | 苏州白垩纪生物科技有限公司 | 一种用于稳定核酸分子的试剂组合物及其应用 |
| WO2022155246A1 (en) | 2021-01-12 | 2022-07-21 | Definitive Biotechnologies Llc | Device and method for detecting nucleic acids in biological samples |
| CN114847272A (zh) * | 2021-02-03 | 2022-08-05 | 上海究本生物科技有限公司 | 一种稳定化生物学样本遗传信息物质的组合物 |
| CN113373031B (zh) * | 2021-08-13 | 2021-11-16 | 北京健为医学检验实验室有限公司 | 一种喷雾型的游离dna样本保存管及应用 |
| CN113736755B (zh) * | 2021-08-18 | 2024-01-19 | 江苏默乐生物科技股份有限公司 | 一种可常温保存的灭活型病毒保存液及其制备方法 |
| CN114235986A (zh) * | 2021-11-25 | 2022-03-25 | 浙江艾兰得生物科技有限公司 | 维生素b1、b2、b6、烟酸、烟酰胺含量的高效液相色谱检测方法 |
| CN115369149A (zh) * | 2022-06-30 | 2022-11-22 | 河北鑫乐医疗器械科技股份有限公司 | 一种尿液游离dna保存剂以及一种尿液保存管 |
| CN116555248B (zh) * | 2023-07-10 | 2023-10-20 | 北京凡知医学科技有限公司 | 一种细菌中高分子量dna提取试剂盒及提取方法 |
| CN117165580B (zh) * | 2023-11-03 | 2024-01-26 | 青岛金域医学检验实验室有限公司 | 一种用于稳定样本中核酸的组合物、制备方法及其应用 |
| CN119061004B (zh) * | 2024-11-07 | 2025-02-14 | 北京市疾病预防控制中心 | 一种痰液样本微生物菌群核酸dna保存液 |
Family Cites Families (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4308264A (en) * | 1981-01-28 | 1981-12-29 | Abbott Laboratories | Stabilized, dilute aqueous preparation of 1α,25-dihydroxycholecalciferol for neonatal administration |
| US5346999A (en) * | 1985-01-18 | 1994-09-13 | Applied Biosystems, Inc. | Method of nucleic acid extraction |
| DE3689398T2 (de) | 1985-01-18 | 1994-07-14 | Applied Biosystems | Verfahren zum Extrahieren von Nukleinsäuren aus Zellen. |
| US4925796A (en) * | 1986-03-07 | 1990-05-15 | Massachusetts Institute Of Technology | Method for enhancing glycoprotein stability |
| CA1317860C (en) | 1987-04-01 | 1993-05-18 | Daniel Louis Kacian | Techniques for preparing specimens for bacterial assays |
| US4808328A (en) * | 1987-05-08 | 1989-02-28 | Joseph N. Cooper | Iodine-based antiseptic cleanser composition |
| US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
| WO1989006704A1 (en) | 1988-01-11 | 1989-07-27 | Microprobe Corporation | Oligonucleotide probes for detection of periodontal pathogens |
| US5128247A (en) | 1989-08-14 | 1992-07-07 | Board Of Regents, The University Of Texas System | Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources |
| US5747339A (en) * | 1990-06-25 | 1998-05-05 | Research Foundation For Microbial Diseases Of Osaka | Non-A, non-B hepatitis virus genomic CDNA and antigen polypeptide |
| US5422241A (en) | 1991-07-03 | 1995-06-06 | Ambion, Inc. | Methods for the recovery of nucleic acids from reaction mixtures |
| BR9206341A (pt) * | 1991-08-06 | 1994-11-08 | World Health Org | Processo de isolamento de DNA |
| US5648215A (en) * | 1992-05-13 | 1997-07-15 | Board Of Regents, The University Of Texas System | Telomerase diagnostic methods |
| GB9403423D0 (en) * | 1994-02-23 | 1994-04-13 | Unilever Plc | Novel exo-(1-4)- beta-D galactanase |
| US5658749A (en) * | 1994-04-05 | 1997-08-19 | Corning Clinical Laboratories, Inc. | Method for processing mycobacteria |
| CA2147593C (en) | 1994-04-22 | 2008-07-29 | Hyman C. Birnboim | Dual purpose tissue fixative |
| US5643767A (en) | 1994-05-02 | 1997-07-01 | The Rockefeller University | Process for isolating cellular components |
| US5945515A (en) * | 1995-07-31 | 1999-08-31 | Chomczynski; Piotr | Product and process for isolating DNA, RNA and proteins |
| WO1998044158A1 (en) | 1997-03-28 | 1998-10-08 | Epitope, Inc. | Simultaneous collection of dna and non-nucleic analytes from oral fluids |
| US20080064108A1 (en) | 1997-12-10 | 2008-03-13 | Tony Baker | Urine Preservation System |
| EP1038028A2 (en) | 1997-12-10 | 2000-09-27 | Sierra Diagnostics, Inc. | Methods and reagents for preservation of dna in bodily fluids |
| US7569342B2 (en) | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| US6204375B1 (en) | 1998-07-31 | 2001-03-20 | Ambion, Inc. | Methods and reagents for preserving RNA in cell and tissue samples |
| DE19836559A1 (de) | 1998-08-12 | 2000-03-23 | Antigen Gmbh | Gefäß zur Entnahme von Blut |
| AU5620600A (en) | 1999-06-16 | 2001-01-02 | University Of Cincinnati, The | Agent and process for isolation of extra-chromosomal nucleic acids |
| US6242188B1 (en) | 1999-07-30 | 2001-06-05 | Applied Gene Technologies, Inc. | Sample processing to release nucleic acids for direct detection |
| EP1244811A1 (en) | 1999-11-10 | 2002-10-02 | Ligochem Inc. | Method for isolating dna from a proteinaceous medium and kit for performing method |
| DE10006662A1 (de) | 2000-02-15 | 2001-08-23 | Antigen Produktions Gmbh | Gefäß zur Nukleinsäureanalytik |
| DE10031236A1 (de) | 2000-06-27 | 2002-01-10 | Qiagen Gmbh | Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien |
| US6602718B1 (en) | 2000-11-08 | 2003-08-05 | Becton, Dickinson And Company | Method and device for collecting and stabilizing a biological sample |
| US7029840B2 (en) | 2000-11-15 | 2006-04-18 | Becton, Dickinson And Company | Method for preservation of cells and nucleic acid targets |
| US6503716B1 (en) | 2000-11-28 | 2003-01-07 | Pe Corporation (Ny) | Compositions and methods for extracting a nucleic acid |
| US6911308B2 (en) | 2001-01-05 | 2005-06-28 | Exact Sciences Corporation | Methods for detecting, grading or monitoring an H. pylori infection |
| US20100120078A1 (en) | 2001-08-16 | 2010-05-13 | Tony Baker | Urine Stabilization System |
| US7148343B2 (en) * | 2001-10-12 | 2006-12-12 | Gentra Systems, Inc. | Compositions and methods for using a solid support to purify RNA |
| JP2003235555A (ja) * | 2002-02-08 | 2003-08-26 | Jsr Corp | 一本鎖核酸および／または二本鎖核酸の単離方法 |
| JP2005524850A (ja) * | 2002-05-07 | 2005-08-18 | ベクトン・ディキンソン・アンド・カンパニー | 採集装置 |
| US7482116B2 (en) | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
| US20040101859A1 (en) | 2002-11-25 | 2004-05-27 | Cepheid | Compositions, methods and kits for polynucleotide amplification reactions and microfluidic devices |
| DE602004032125D1 (de) * | 2003-05-07 | 2011-05-19 | Coris Bioconcept Sprl | Einstufige oligochromatographische vorrichtung und verfahren zu ihrer verwendung |
| US7465562B2 (en) | 2003-05-19 | 2008-12-16 | Brandeis University | Nucleic acid processing methods, kits and devices |
| EP1641944B1 (en) * | 2003-07-09 | 2011-06-29 | Genvault Corporation | Room temperature elution of nucleic acids |
| US20050059024A1 (en) | 2003-07-25 | 2005-03-17 | Ambion, Inc. | Methods and compositions for isolating small RNA molecules |
| WO2005054466A2 (en) | 2003-07-25 | 2005-06-16 | Ambion, Inc. | Methods and compositions for preparing rna from a fixed sample |
| CA2533910A1 (en) * | 2003-07-29 | 2005-02-24 | Sigma-Aldrich Co. | Methods and compositions for amplification of dna |
| US7638309B2 (en) | 2003-12-03 | 2009-12-29 | Council Of Science And Industrial Research | Method for detecting pathogenic mycobacteria in clinical specimens |
| EP1584923A3 (en) | 2004-04-07 | 2006-01-04 | Roche Diagnostics GmbH | Stabilization of biomolecules in samples |
| US20070244314A1 (en) | 2004-05-18 | 2007-10-18 | Fujifilm Corporation | Method For Extracting Nucleic Acid And Nucleic Acid-Extracting Apparatus |
| JP2008509226A (ja) * | 2004-05-24 | 2008-03-27 | ジェンボールト コーポレイション | 回収可能な形式での安定なタンパク質保管および安定な核酸保管 |
| JP2006087394A (ja) * | 2004-09-27 | 2006-04-06 | Wako Pure Chem Ind Ltd | 核酸抽出方法および核酸抽出キット |
| US20060078894A1 (en) * | 2004-10-12 | 2006-04-13 | Winkler Matthew M | Methods and compositions for analyzing nucleic acids |
| TWI294460B (en) | 2004-12-23 | 2008-03-11 | Ind Tech Res Inst | Method for stabilizing nucleic acids |
| CN101175853A (zh) | 2005-03-16 | 2008-05-07 | Dna吉诺特克股份有限公司 | 用于保存来自体液的核酸的组合物和方法 |
| WO2007049326A1 (ja) | 2005-10-24 | 2007-05-03 | Wako Pure Chemical Industries, Ltd. | 核酸抽出方法および核酸抽出キット |
| US20070202511A1 (en) | 2006-02-28 | 2007-08-30 | Sigma-Aldrich Co. | Methods and compositions for the rapid isolation of small RNA molecules |
| JP5479895B2 (ja) * | 2006-07-25 | 2014-04-23 | アジレント・テクノロジーズ・インク | Ｄｎａポリメラーゼの保存及び使用のための両性イオン洗剤 |
| AU2007296460B2 (en) | 2006-09-12 | 2014-05-22 | Sierra Molecular Corporation | Removal of molecular assay interferences for nucleic acids employing buffered solutions of chaotropes |
| US8097419B2 (en) | 2006-09-12 | 2012-01-17 | Longhorn Vaccines & Diagnostics Llc | Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009 |
| US8652782B2 (en) * | 2006-09-12 | 2014-02-18 | Longhorn Vaccines & Diagnostics, Llc | Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids |
| US8080645B2 (en) | 2007-10-01 | 2011-12-20 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection/transport compositions and methods |
| GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
| US9683256B2 (en) * | 2007-10-01 | 2017-06-20 | Longhorn Vaccines And Diagnostics, Llc | Biological specimen collection and transport system |
| US20140038174A1 (en) * | 2011-04-26 | 2014-02-06 | Longhorn Vaccines And Diagnostics, Llc | Compositions and Methods for Detecting and Identifying Nucleic Acid Sequences in Biological Samples |
| ES2552858T3 (es) | 2007-10-01 | 2015-12-02 | Longhorn Vaccines And Diagnostics, Llc | Recogida de muestras biológicas y sistema de transporte y métodos de uso |
| US20100209927A1 (en) * | 2007-11-06 | 2010-08-19 | Menon Vinod P | Processing device tablet |
| US20100003748A1 (en) | 2008-07-03 | 2010-01-07 | Tony Baker | Compositions, systems, and methods for stabilization of a cell and/or macromolecule |
| JPWO2010064628A1 (ja) * | 2008-12-05 | 2012-05-10 | オリンパス株式会社 | 核酸含有試料の調製方法、試料調製用溶液、及び核酸の解析方法 |
| JP2012511317A (ja) * | 2008-12-12 | 2012-05-24 | ウロジャンテック、ソシエテ、アノニム | 核酸増幅反応の特異性、感度および収量を改善するためのシクロデキストリンの使用 |
| US20110256292A1 (en) | 2010-04-16 | 2011-10-20 | Purgatorio James C | Device and method for making food items |
| EP2598661B1 (en) | 2010-07-26 | 2017-09-27 | Biomatrica, INC. | Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
| WO2012018638A2 (en) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures |
| CA2779850C (en) | 2011-06-17 | 2016-08-09 | Norgen Biotek Corporation | Methods, reagents and kits for preservation of nucleic acids in biological samples |
| JP2014526255A (ja) * | 2011-09-13 | 2014-10-06 | キアゲン ゲーエムベーハー | 獣医学的全血試料から核酸を単離するための方法 |
| WO2013117967A1 (en) * | 2012-02-10 | 2013-08-15 | Reametrix Inc. | Compositions and methods for sputum samples preparation, and kit |
| WO2013117968A1 (en) * | 2012-02-10 | 2013-08-15 | Reametrix Inc. | Methods for lysing bacteria from sample and isolating cellular components therefrom, and kits therefor |
| CA2868805C (en) * | 2012-03-28 | 2018-09-04 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for the collection and isolation of nucleic acids from biological specimens |
| US9540635B2 (en) * | 2012-05-09 | 2017-01-10 | Bio-Rad Laboratories, Inc. | Buffer for one-step DNA extraction |
| WO2013176730A1 (en) * | 2012-05-22 | 2013-11-28 | Life Technologies As | Recombinant antibody compositions and methods of use thereof |
| US8861976B2 (en) * | 2012-06-29 | 2014-10-14 | Intel Corporation | Transmit and receive MIMO protocols for light array communications |
| JP2014039481A (ja) * | 2012-08-21 | 2014-03-06 | Seiko Epson Corp | Ｒｎａの抽出方法 |
| CA2886389A1 (en) | 2012-09-28 | 2014-04-03 | Cepheid | Methods for dna and rna extraction from fixed paraffin-embedded tissue samples |
| US9840731B2 (en) | 2013-03-14 | 2017-12-12 | Gentegra, Llc | Preservation of biological materials in non-aqueous fluid media |
| JP2017510452A (ja) * | 2014-03-07 | 2017-04-13 | エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ | 生物学的生成物の分画のための装置及び方法 |
| CA2956303A1 (en) * | 2014-08-15 | 2016-02-18 | Counsyl, Inc. | High-throughput sample processing systems and methods of use |
| JP2016067275A (ja) * | 2014-09-30 | 2016-05-09 | セイコーエプソン株式会社 | 核酸精製デバイス |
| US20170362586A1 (en) * | 2014-12-09 | 2017-12-21 | Corning Incorporated | Methods and kits for purifying plasmid dna |
| CA2985652C (en) | 2015-05-14 | 2020-03-10 | Gerald W. FISHER | Rapid methods for the extraction of nucleic acids from biological samples |
| US20160348153A1 (en) * | 2015-05-29 | 2016-12-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv | Extraction and preservation of nucleic acid molecules from pathogens |
| EP3319930A4 (en) * | 2015-07-07 | 2019-04-10 | NanoBio Corporation | METHOD AND COMPOSITIONS FOR STABILIZING PROTEINS |
| SI3568475T1 (sl) * | 2017-01-16 | 2023-05-31 | Spectrum Solutions L. L. C. | Raztopina za ohranjanje nukleinske kisline in načini uporabe |
| JP2023521803A (ja) * | 2020-04-14 | 2023-05-25 | スペクトラム・ソリューションズ・エルエルシー | ウイルス核酸の検出用製品及びその検出方法 |
-
2018
- 2018-01-16 SI SI201830891T patent/SI3568475T1/sl unknown
- 2018-01-16 ES ES18739053T patent/ES2942577T3/es active Active
- 2018-01-16 HR HRP20230345TT patent/HRP20230345T1/hr unknown
- 2018-01-16 FI FIEP18739053.9T patent/FI3568475T3/fi active
- 2018-01-16 US US15/872,791 patent/US10174362B2/en active Active
- 2018-01-16 EP EP23217733.7A patent/EP4372099A3/en not_active Withdrawn
- 2018-01-16 EP EP18739053.9A patent/EP3568475B1/en active Active
- 2018-01-16 WO PCT/US2018/013862 patent/WO2018132827A1/en not_active Ceased
- 2018-01-16 EP EP22215941.0A patent/EP4177342B1/en active Active
- 2018-01-16 CA CA3042088A patent/CA3042088A1/en active Pending
- 2018-01-16 PT PT187390539T patent/PT3568475T/pt unknown
- 2018-01-16 HU HUE18739053A patent/HUE062204T2/hu unknown
- 2018-01-16 DK DK18739053.9T patent/DK3568475T3/da active
- 2018-01-16 LT LTEPPCT/US2018/013862T patent/LT3568475T/lt unknown
- 2018-01-16 MX MX2019006767A patent/MX374141B/es active IP Right Grant
- 2018-01-16 CN CN201880005081.0A patent/CN110072999B/zh active Active
- 2018-01-16 CN CN202110968028.4A patent/CN113801876A/zh active Pending
- 2018-01-16 JP JP2019559004A patent/JP6652692B2/ja active Active
- 2018-01-16 PL PL18739053.9T patent/PL3568475T3/pl unknown
- 2018-10-31 US US16/176,210 patent/US10774368B2/en active Active
-
2019
- 2019-06-10 MX MX2020003996A patent/MX2020003996A/es unknown
-
2020
- 2020-01-23 JP JP2020009118A patent/JP2020058396A/ja active Pending
- 2020-09-14 US US17/020,516 patent/US11655495B2/en active Active
-
2022
- 2022-02-10 JP JP2022019552A patent/JP2022069447A/ja active Pending
-
2023
- 2023-04-17 US US18/135,720 patent/US20230304071A1/en active Pending
- 2023-06-07 CY CY20231100269T patent/CY1126046T1/el unknown
-
2024
- 2024-09-03 JP JP2024151398A patent/JP2024163225A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2019006767A (es) | Solucion de conservacion de acido nucleico y metodos de elaboracion y uso. | |
| CL2022002379A1 (es) | Molécula de ácido nucleico interferente corto (sina); composición que la comprende; y su uso. | |
| MX2022003477A (es) | Medio de cultivo celular complementado con taurina y metodos de uso. | |
| CL2019000586A1 (es) | Composiciones de toxinas clostridiales no proteicas. | |
| AR111834A1 (es) | Composiciones líquidas estables de inoculantes que comprenden dodecano | |
| AR103174A1 (es) | Composiciones adyuvantes acuosas que contienen electrolito, composiciones que contienen ingrediente activo y su uso | |
| UY37919A (es) | Composiciones de hierbas con mejor biodisponibilidad | |
| AR096127A1 (es) | Composición, uso y sistema de fertirrigación | |
| BR112017013277A2 (pt) | composição aquosa, método de amplificação isotérmica de ácido nucleico e kit | |
| BR112018075185A2 (pt) | formulações análogas de hidróxi metionina adequadas para aplicações de produtos químicos especializados | |
| BR112018071519A2 (pt) | técnicas para avaliação comparativa de estratégias de pareamento em um sistema de centro de contato | |
| CL2017001903A1 (es) | Composición novedosa para uso en el incremento de eficacia de injerto de células madre hematopoyéticas después del trasplante | |
| MX2021005762A (es) | Solución de preservación de rna y métodos de fabricación y uso. | |
| BR112017024191A2 (pt) | composição aquosa, método de amplificação de ácido nucleico e kit | |
| BR112017006533A2 (pt) | usos de trealose em suspensões celulares | |
| MXPA05012319A (es) | Suministro de compuestos con celulas sanguineas rehidratadas. | |
| CU20170108A7 (es) | Composición ácida a base de leonardita y aminoácidos | |
| BR112018006375A2 (pt) | sanitizante de pele à base de álcool que tem propriedades microbicidas | |
| EA201990163A1 (ru) | Консервация микроорганизмов | |
| BR112016006644A2 (pt) | método para introduzir uma substância em uma planta, recipiente para uso em um método, e, combinação de uma planta e um recipiente | |
| AR116582A1 (es) | Composiciones de pongamia, sus métodos de preparación y análisis y sus usos | |
| MX2017011934A (es) | Formas solidas de menaquinoles. | |
| AR112044A1 (es) | Solución de limpieza de membrana y método de limpieza de membrana acelerado mediante el uso de la misma | |
| UY35228A (es) | Composiciones acuosas de cloquintocet-mexilo de temperatura estable | |
| CY1123363T1 (el) | Απομονωση νουκλεϊνικων οξεων |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |