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MX2019005567A - Metodo para el muestreo de correintes de fluido para controlar contaminantes en un flujo continuo. - Google Patents

Metodo para el muestreo de correintes de fluido para controlar contaminantes en un flujo continuo.

Info

Publication number
MX2019005567A
MX2019005567A MX2019005567A MX2019005567A MX2019005567A MX 2019005567 A MX2019005567 A MX 2019005567A MX 2019005567 A MX2019005567 A MX 2019005567A MX 2019005567 A MX2019005567 A MX 2019005567A MX 2019005567 A MX2019005567 A MX 2019005567A
Authority
MX
Mexico
Prior art keywords
fluid stream
continuous flow
fluid streams
sampling fluid
monitoring contaminants
Prior art date
Application number
MX2019005567A
Other languages
English (en)
Inventor
Lobedann Martin
Schwan Peter
KISTLER Viktorija
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP16198334.1A external-priority patent/EP3141594A3/en
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX2019005567A publication Critical patent/MX2019005567A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12Purification
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14Ultrafiltration; Microfiltration
    • B01D61/147Microfiltration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14Ultrafiltration; Microfiltration
    • B01D61/20Accessories; Auxiliary operations
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/58Multistep processes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04Filters; Permeable or porous membranes or plates, e.g. dialysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02Filters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06Investigating concentration of particle suspensions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2311/00Details relating to membrane separation process operations and control
    • B01D2311/26Further operations combined with membrane separation processes
    • B01D2311/2626Absorption or adsorption
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D36/00Filter circuits or combinations of filters with other separating devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/06Preparation
    • G01N30/14Preparation by elimination of some components

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Water Supply & Treatment (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)
  • Public Health (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Epidemiology (AREA)

Abstract

Se revela en la presente un método para controlar la concentración de al menos un tipo de contaminante en una corriente de fluido, que comprende las etapas de suministro de al menos dos unidades operativas, suministro de una corriente de fluido, que pasa por dichas al menos dos unidades operativas en una vía de flujo, muestreo de la corriente de fluido en una manera válida predeterminada, determinación de la concentración del contaminante en la muestra a fin de controlar la concentración del contaminante en la corriente de fluido, en donde el método se lleva a cabo en condiciones continuas, cerradas y reducidas en agentes patógenos.
MX2019005567A 2016-11-11 2017-11-03 Metodo para el muestreo de correintes de fluido para controlar contaminantes en un flujo continuo. MX2019005567A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16198334.1A EP3141594A3 (en) 2016-11-11 2016-11-11 Method for sampling fluid streams for monitoring contaminants in a continuous flow
EP17191961 2017-09-19
PCT/EP2017/078143 WO2018086997A1 (en) 2016-11-11 2017-11-03 Method for sampling fluid streams for monitoring contaminants in a continuous flow

Publications (1)

Publication Number Publication Date
MX2019005567A true MX2019005567A (es) 2019-08-12

Family

ID=60327296

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019005567A MX2019005567A (es) 2016-11-11 2017-11-03 Metodo para el muestreo de correintes de fluido para controlar contaminantes en un flujo continuo.

Country Status (13)

Country Link
US (1) US20190359930A1 (es)
EP (1) EP3538636A1 (es)
JP (1) JP2019535260A (es)
KR (1) KR20190079662A (es)
CN (1) CN109963935A (es)
AU (1) AU2017358509A1 (es)
CA (1) CA3043294A1 (es)
IL (1) IL266423A (es)
MX (1) MX2019005567A (es)
RU (1) RU2755065C2 (es)
SG (2) SG11201903531UA (es)
TW (1) TW201831889A (es)
WO (1) WO2018086997A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201816871D0 (en) 2018-10-17 2018-11-28 Ge Healthcare Bio Sciences Ab A bioprocessing fluid sensor arrangement
CN110935274A (zh) * 2019-09-18 2020-03-31 赵兰坤 一种降低氨基酸发酵染菌的空气过滤装置
US20210387146A1 (en) * 2020-06-11 2021-12-16 Duke University Collection of cells from biological fluid
WO2025036696A1 (en) * 2023-08-17 2025-02-20 Cytiva Sweden Ab Downstream bioprocessing process using batch tracking

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000319294A (ja) * 1999-05-11 2000-11-21 Asahi Chem Ind Co Ltd 生物由来高分子溶液精製方法
KR101238798B1 (ko) * 2004-09-30 2013-03-04 바이엘 헬스케어, 엘엘씨 생물학적 분자의 통합된 연속 제조를 위한 장치 및 방법
US7981679B2 (en) * 2007-02-16 2011-07-19 Nalco Company Method of monitoring bulk (total) microbiological activity in process streams
US8991270B2 (en) * 2008-11-24 2015-03-31 Koninklijke Philips N.V. Method and apparatus for rapid filter analysis of fluid samples
JP2013544524A (ja) * 2010-12-06 2013-12-19 ターポン バイオシステムズ,インコーポレイテッド 生物学的生成物の連続プロセス法
CN202047067U (zh) * 2010-12-13 2011-11-23 南宁庞博生物工程有限公司 生物酶液体和饮料的多级超滤纯化分离浓缩装置
CA3204402A1 (en) * 2012-03-26 2013-10-03 Sanofi Stable anti-cxcr5 igg4 antibody formulations
EP2682168A1 (en) * 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
SI2914612T1 (sl) * 2012-10-30 2019-03-29 F. Hoffmann-La Roche Ag Čiščenje polipeptidov z uporabo dvostopenjske tangencialne ultrafiltracije
WO2015084996A1 (en) * 2013-12-03 2015-06-11 Millennium Pharmaceuticals, Inc. Compounds and compositions for imaging gcc-expressing cells
JP2017510452A (ja) * 2014-03-07 2017-04-13 エイジェンシー・フォー・サイエンス,テクノロジー・アンド・リサーチ 生物学的生成物の分画のための装置及び方法
US9908064B2 (en) * 2015-02-06 2018-03-06 Leidos, Inc. Portable fluidic platform for rapid cell-free production of protein biologics
EP3015542A1 (de) * 2015-05-07 2016-05-04 Bayer Technology Services GmbH Modulare anlage und verfahren zur kontinuierlichen, keimreduzierten produktion und/oder aufbereitung eines produktes

Also Published As

Publication number Publication date
TW201831889A (zh) 2018-09-01
SG10202104821SA (en) 2021-06-29
AU2017358509A1 (en) 2019-05-09
RU2019117905A (ru) 2020-12-11
RU2019117905A3 (es) 2021-03-10
US20190359930A1 (en) 2019-11-28
KR20190079662A (ko) 2019-07-05
EP3538636A1 (en) 2019-09-18
RU2755065C2 (ru) 2021-09-13
JP2019535260A (ja) 2019-12-12
CA3043294A1 (en) 2018-05-17
IL266423A (en) 2019-06-30
SG11201903531UA (en) 2019-05-30
CN109963935A (zh) 2019-07-02
WO2018086997A1 (en) 2018-05-17

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