MX2019003427A - Composiciones para cultivo celular y metodos para la produccion de polipeptidos. - Google Patents
Composiciones para cultivo celular y metodos para la produccion de polipeptidos.Info
- Publication number
- MX2019003427A MX2019003427A MX2019003427A MX2019003427A MX2019003427A MX 2019003427 A MX2019003427 A MX 2019003427A MX 2019003427 A MX2019003427 A MX 2019003427A MX 2019003427 A MX2019003427 A MX 2019003427A MX 2019003427 A MX2019003427 A MX 2019003427A
- Authority
- MX
- Mexico
- Prior art keywords
- cell culture
- methods
- polypeptide production
- culture compositions
- compositions
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 238000004113 cell culture Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000006143 cell culture medium Substances 0.000 abstract 2
- 230000010261 cell growth Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Se proporcionan medios de cultivo celular, tales como los medios de cultivo celular químicamente definidos, como son los métodos para utilizar los medios para el crecimiento celular (i.e. cultivo celular) y la producción de polipéptidos (e.g. anticuerpos). También se proporcionan las composiciones que comprenden los polipéptidos producidos por los métodos.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261637778P | 2012-04-24 | 2012-04-24 | |
| US201261637780P | 2012-04-24 | 2012-04-24 | |
| US13/841,864 US20130281355A1 (en) | 2012-04-24 | 2013-03-15 | Cell culture compositions and methods for polypeptide production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019003427A true MX2019003427A (es) | 2020-11-12 |
Family
ID=49380652
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014012838A MX363493B (es) | 2012-04-24 | 2013-04-24 | Composiciones para cultivo celular y metodos para la produccion de polipetidos. |
| MX2019003427A MX2019003427A (es) | 2012-04-24 | 2014-10-23 | Composiciones para cultivo celular y metodos para la produccion de polipeptidos. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014012838A MX363493B (es) | 2012-04-24 | 2013-04-24 | Composiciones para cultivo celular y metodos para la produccion de polipetidos. |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US20130281355A1 (es) |
| EP (2) | EP2841561B1 (es) |
| JP (4) | JP6367792B2 (es) |
| KR (2) | KR102115052B1 (es) |
| CN (3) | CN104428409A (es) |
| AR (1) | AR090822A1 (es) |
| AU (2) | AU2013251647B2 (es) |
| BR (1) | BR112014026308A8 (es) |
| CA (1) | CA2871006C (es) |
| ES (1) | ES2716301T3 (es) |
| HK (1) | HK1208496A1 (es) |
| HR (1) | HRP20190484T1 (es) |
| IL (1) | IL235235A0 (es) |
| MX (2) | MX363493B (es) |
| MY (1) | MY181513A (es) |
| NZ (1) | NZ701791A (es) |
| PL (1) | PL2841561T3 (es) |
| RU (2) | RU2678142C2 (es) |
| SG (2) | SG11201406903SA (es) |
| SI (1) | SI2841561T1 (es) |
| WO (1) | WO2013163294A1 (es) |
| ZA (2) | ZA201408092B (es) |
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| JPH0720293B2 (ja) | 1986-11-20 | 1995-03-06 | 三洋電機株式会社 | リモ−トコントロ−ル受信回路 |
| US9150645B2 (en) | 2012-04-20 | 2015-10-06 | Abbvie, Inc. | Cell culture methods to reduce acidic species |
| WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
| AR095348A1 (es) * | 2013-03-15 | 2015-10-07 | Genentech Inc | Medios de cultivo celular y métodos de producción de anticuerpos |
| KR20210037745A (ko) | 2013-03-15 | 2021-04-06 | 제넨테크, 인크. | 항산화제를 함유하는 세포 배양 조성물 및 폴리펩티드 생산 방법 |
| EP3052640A2 (en) * | 2013-10-04 | 2016-08-10 | AbbVie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| GB201708655D0 (en) | 2017-05-31 | 2017-07-12 | Ucb Biopharma Sprl | Cell culture methods |
| WO2018229802A1 (en) * | 2017-06-16 | 2018-12-20 | Ge Healthcare Bio-Sciences Ab | Method for predicting outcome of and modelling of a process in a bioreactor |
| EP3492582A1 (en) | 2017-12-01 | 2019-06-05 | UCB Biopharma SPRL | Cell culture methods |
| CN111500662A (zh) * | 2018-06-25 | 2020-08-07 | 深圳市菲鹏生物制药股份有限公司 | 调节cho-k1表达系统所分泌抗体的酸性峰含量的方法 |
| WO2021087232A1 (en) * | 2019-10-31 | 2021-05-06 | William Marsh Rice University | Engineered cells for controlled production |
| US11186625B2 (en) | 2019-12-06 | 2021-11-30 | Regeneran Pharmaceuticals, Inc. | Anti-VEGF protein compositions and methods for producing the same |
| WO2021153723A1 (ja) | 2020-01-31 | 2021-08-05 | 中外製薬株式会社 | 着色を抑制したポリペプチドを含む組成物の製造方法 |
| AU2021268026A1 (en) | 2020-05-08 | 2023-01-19 | Regeneron Pharmaceuticals, Inc. | VEGF traps and mini-traps and methods for treating ocular disorders and cancer |
| GB202012991D0 (en) | 2020-08-20 | 2020-10-07 | Ucb Biopharma Sprl | Cell culture processes |
| JP2023554489A (ja) * | 2020-12-22 | 2023-12-27 | ノバルティス アーゲー | 細胞培養中の分泌された組換え発現タンパク質中のシステイン残基の酸化レベルを低減するための方法 |
| WO2022204120A1 (en) * | 2021-03-23 | 2022-09-29 | Biogen Ma Inc. | Reducing host cell impurities during recombinant protein production |
| GB202105424D0 (en) | 2021-04-16 | 2021-06-02 | UCB Biopharma SRL | Cell culture processes |
| WO2023031409A1 (en) | 2021-09-02 | 2023-03-09 | Boehringer Ingelheim International Gmbh | Method of determining a future color value or corresponding property and arrangement therefor |
| KR102682066B1 (ko) * | 2021-10-12 | 2024-07-05 | 프레스티지바이오로직스 주식회사 | 항체 집단의 제조 방법 |
| CN115807135A (zh) * | 2022-12-13 | 2023-03-17 | 上海臻格生物技术有限公司 | 一种生物反应器泡沫控制方法 |
| GB202318647D0 (en) | 2023-12-06 | 2024-01-17 | Ucb Biopharma Sprl | Cell culture processes |
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| JP5349474B2 (ja) * | 2007-07-20 | 2013-11-20 | ドングク・ユニヴァーシティー・インダストリー−アカデミック・コーオペレーション・ファンデーション | 間葉系幹細胞を利用して毛乳頭組職を製造する方法 |
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| JO3672B1 (ar) * | 2008-12-15 | 2020-08-27 | Regeneron Pharma | أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9). |
| US9540426B2 (en) * | 2009-10-06 | 2017-01-10 | Bristol-Myers Squibb Company | Mammalian cell culture processes for protein production |
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-
2013
- 2013-03-15 US US13/841,864 patent/US20130281355A1/en not_active Abandoned
- 2013-04-24 RU RU2014147018A patent/RU2678142C2/ru active
- 2013-04-24 CN CN201380032959.7A patent/CN104428409A/zh active Pending
- 2013-04-24 CN CN202010250367.4A patent/CN111440758B/zh active Active
- 2013-04-24 SG SG11201406903SA patent/SG11201406903SA/en unknown
- 2013-04-24 RU RU2018146497A patent/RU2018146497A/ru unknown
- 2013-04-24 SG SG10201810830UA patent/SG10201810830UA/en unknown
- 2013-04-24 AU AU2013251647A patent/AU2013251647B2/en active Active
- 2013-04-24 HK HK15109118.1A patent/HK1208496A1/xx unknown
- 2013-04-24 KR KR1020147032389A patent/KR102115052B1/ko active Active
- 2013-04-24 SI SI201331376T patent/SI2841561T1/sl unknown
- 2013-04-24 WO PCT/US2013/037992 patent/WO2013163294A1/en not_active Ceased
- 2013-04-24 ES ES13720203T patent/ES2716301T3/es active Active
- 2013-04-24 EP EP13720203.2A patent/EP2841561B1/en not_active Revoked
- 2013-04-24 AR ARP130101367 patent/AR090822A1/es unknown
- 2013-04-24 BR BR112014026308A patent/BR112014026308A8/pt not_active Application Discontinuation
- 2013-04-24 EP EP18213796.8A patent/EP3533864A1/en active Pending
- 2013-04-24 PL PL13720203T patent/PL2841561T3/pl unknown
- 2013-04-24 JP JP2015509107A patent/JP6367792B2/ja active Active
- 2013-04-24 MY MYPI2014003007A patent/MY181513A/en unknown
- 2013-04-24 CN CN202411848274.6A patent/CN119979437A/zh active Pending
- 2013-04-24 NZ NZ701791A patent/NZ701791A/en unknown
- 2013-04-24 MX MX2014012838A patent/MX363493B/es unknown
- 2013-04-24 CA CA2871006A patent/CA2871006C/en active Active
- 2013-04-24 KR KR1020207014171A patent/KR102339106B1/ko active Active
- 2013-04-24 HR HRP20190484TT patent/HRP20190484T1/hr unknown
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2014
- 2014-10-21 IL IL235235A patent/IL235235A0/en unknown
- 2014-10-23 MX MX2019003427A patent/MX2019003427A/es unknown
- 2014-11-05 ZA ZA2014/08092A patent/ZA201408092B/en unknown
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2017
- 2017-11-03 ZA ZA2017/07452A patent/ZA201707452B/en unknown
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2018
- 2018-07-05 JP JP2018128429A patent/JP7323272B2/ja active Active
-
2019
- 2019-04-02 AU AU2019202259A patent/AU2019202259B2/en active Active
-
2021
- 2021-03-16 JP JP2021042702A patent/JP2021104023A/ja not_active Withdrawn
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2023
- 2023-07-28 JP JP2023123219A patent/JP2023156371A/ja active Pending
- 2023-10-30 US US18/497,162 patent/US20240093143A1/en not_active Abandoned
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