[go: up one dir, main page]

MX2019003206A - Gel de acido hialuronico con un cation de zinc divalente. - Google Patents

Gel de acido hialuronico con un cation de zinc divalente.

Info

Publication number
MX2019003206A
MX2019003206A MX2019003206A MX2019003206A MX2019003206A MX 2019003206 A MX2019003206 A MX 2019003206A MX 2019003206 A MX2019003206 A MX 2019003206A MX 2019003206 A MX2019003206 A MX 2019003206A MX 2019003206 A MX2019003206 A MX 2019003206A
Authority
MX
Mexico
Prior art keywords
zinc cation
hyaluronic acid
divalent zinc
acid gel
hydrogel composition
Prior art date
Application number
MX2019003206A
Other languages
English (en)
Inventor
Steven Harris Craig
Säwén Elin
Jing Jing Laura
Karlsson Anders
Original Assignee
Nestle Skin Health Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestle Skin Health Sa filed Critical Nestle Skin Health Sa
Publication of MX2019003206A publication Critical patent/MX2019003206A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/025—Other specific inorganic materials not covered by A61L27/04 - A61L27/12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

La presente invencion se refiere a un metodo de preparacion de una composicion de hidrogel inyectable esterilizada, que comprende los pasos de: a) entrelazar covalentemente un glucosaminoglucano usando un agente de entrelazamiento bi- o poli-funcional para formar un glucosaminoglucano entrelazado covalentemente, b) hinchar el glucosaminoglucano entrelazado covalentemente en una solucion que comprende un cation de zinc divalente para formar una composicion de hidrogel, y c) esterilizar la composicion de hidrogel mediante tratamiento en autoclave para formar una composicion de hidrogel inyectable esterilizada, y a composiciones de hidrogel inyectables esterilizadas obtenibles mediante dicho metodo.
MX2019003206A 2016-09-21 2017-09-20 Gel de acido hialuronico con un cation de zinc divalente. MX2019003206A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16189972 2016-09-21
PCT/EP2017/073823 WO2018055002A1 (en) 2016-09-21 2017-09-20 Hyaluronic acid gel with a divalent zinc cation

Publications (1)

Publication Number Publication Date
MX2019003206A true MX2019003206A (es) 2019-09-18

Family

ID=56979489

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019003206A MX2019003206A (es) 2016-09-21 2017-09-20 Gel de acido hialuronico con un cation de zinc divalente.

Country Status (11)

Country Link
US (1) US10898613B2 (es)
EP (1) EP3515511A1 (es)
JP (1) JP2019532708A (es)
KR (1) KR20190070327A (es)
CN (1) CN109952117A (es)
AU (1) AU2017329872A1 (es)
BR (1) BR112019005391A2 (es)
CA (1) CA3037651A1 (es)
MX (1) MX2019003206A (es)
RU (1) RU2019111102A (es)
WO (1) WO2018055002A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201900017387A1 (it) * 2019-09-27 2021-03-27 Bmg Pharma S P A Idrogelo a base di zinco gluconato ed esteri dell’acido ialuronico
US11679076B2 (en) * 2020-08-06 2023-06-20 T-ACE Medical Co., Ltd. Composition for submucosal injection and preparation method thereof
KR102581434B1 (ko) * 2021-02-09 2023-09-22 (주)제테마 히알루론산 필러 조성물의 제조에 사용되는 용액 및 이를 이용한 히알루론산 필러 조성물
FR3122082B1 (fr) 2021-04-26 2024-10-18 Noxelis Produit biocompatible a matrice comprenant un polysaccharide et du chitosane co-reticules
CN119286070A (zh) * 2024-10-30 2025-01-10 陕西科技大学 一种基于铜离子交联改性的透明质酸水凝胶及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU203372B (en) 1989-02-24 1991-07-29 Richter Gedeon Vegyeszet Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient
US5827937A (en) 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
IT1303735B1 (it) * 1998-11-11 2001-02-23 Falorni Italia Farmaceutici S Acidi ialuronici reticolati e loro usi medici.
JP3779200B2 (ja) * 2001-11-28 2006-05-24 電気化学工業株式会社 ヒアルロン酸及び／又はその塩の水溶液の安定化組成物
FR2945293B1 (fr) * 2009-05-11 2011-06-17 Teoxane Procede de preparation d'un gel reticule.
FR2979539B1 (fr) * 2011-09-05 2013-09-27 Teoxane Composition sterile dermo-injectable
CN103181902B (zh) * 2011-12-30 2016-06-08 张文芳 一种凝胶微球及其质控方法
FR2994846B1 (fr) 2012-08-29 2014-12-26 Vivacy Lab Composition, sterilisee, comprenant au moins un acide hyaluronique et de l'ascorbyl phosphate de magnesium
FR3032617B1 (fr) 2015-02-16 2018-03-16 Kylane Laboratoires Sa Procede de preparation d un hydrogel injectable; hydrogel obtenu; utilisation de l hydrogel obtenu
CN105670008B (zh) * 2016-02-02 2019-01-08 华熙福瑞达生物医药有限公司 一种水溶性交联透明质酸干粉及应用
CN105536046B (zh) * 2016-02-26 2018-08-07 闫策 一种含双硫键的可注射骨水泥及制备方法

Also Published As

Publication number Publication date
US10898613B2 (en) 2021-01-26
RU2019111102A (ru) 2020-10-22
AU2017329872A1 (en) 2019-04-11
US20190351105A1 (en) 2019-11-21
EP3515511A1 (en) 2019-07-31
JP2019532708A (ja) 2019-11-14
KR20190070327A (ko) 2019-06-20
WO2018055002A1 (en) 2018-03-29
CA3037651A1 (en) 2018-03-29
BR112019005391A2 (pt) 2019-06-04
CN109952117A (zh) 2019-06-28

Similar Documents

Publication Publication Date Title
MX2019003206A (es) Gel de acido hialuronico con un cation de zinc divalente.
MX2018011053A (es) Acido hialuronico modificado, metodo para preparar el mismo y usos del mismo.
PH12017550075B1 (en) Microstructure using cross-linked hyaluronic acid hydrogel, and method for producing same
WO2012008722A3 (ko) 조직 증강용 충전 조성물
PH12014500767A1 (en) Compositions for the treatment of dry eye
MX370853B (es) Formulaciones que contienen dapagliflozina amorfa.
BR112017005997A2 (pt) método
MX2015017273A (es) Composiciones que comprenden acido hialuronico reticulado y ciclodextrina.
AU2018268713A1 (en) Biopolymer compositions, scaffolds and devices
MX2017001379A (es) Producto antiseptico, proceso para prepararlo y su uso.
BR112019004332A2 (pt) géis injetáveis que compreendem ácido hialurônico reticulado e hidroxiapatita, composição e processo de fabricação dos mesmos
PH12017501473A1 (en) Novel proteins specific for pyoverdine and pyochelin
MX2016007534A (es) Composicion de gel de acido hialuronico que tiene durabilidad.
BR112016009482A8 (pt) composição de revestimento, uso de uma composição de revestimento, processo para preparação de adutos e método para cura de uma composição de revestimento
TN2015000520A1 (en) Pharmaceutical compositions comprising collagen and sodium hyaluronate
EP4378535A3 (en) Antibiotic formulations for lower back pain
BR112017015387A2 (pt) composição em gel tópica, método de tratamento de uma infecção da pele, composição em gel oftálmica, e, método de tratamento de uma afecção infecciosa do olho ou pálpebra
WO2015084883A3 (en) Compositions and methods for treating osteoarthritis
WO2020049552A9 (en) Tissue repair by activated cells
HK1221639A1 (zh) 交联的壳聚糖-丙交酯水凝胶
ZA202206990B (en) High molecular weight esthetic compositions
WO2018118862A8 (en) Injectable hydrogels and applications thereof
EP4410370A3 (en) Compositions for promoting the healing of wounds
MX373912B (es) Terapias antibioticas peptidicas derivadas del bufalo de agua
WO2016007424A3 (en) Zwitterionic hydrogels for delivery of biomolecules