MX2018016091A - Composiciones de fosfolipidos. - Google Patents
Composiciones de fosfolipidos.Info
- Publication number
- MX2018016091A MX2018016091A MX2018016091A MX2018016091A MX2018016091A MX 2018016091 A MX2018016091 A MX 2018016091A MX 2018016091 A MX2018016091 A MX 2018016091A MX 2018016091 A MX2018016091 A MX 2018016091A MX 2018016091 A MX2018016091 A MX 2018016091A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- extract
- modified
- egg yolk
- phospholipid compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 150000003904 phospholipids Chemical class 0.000 title 1
- 102000002322 Egg Proteins Human genes 0.000 abstract 2
- 108010000912 Egg Proteins Proteins 0.000 abstract 2
- 235000013345 egg yolk Nutrition 0.000 abstract 2
- 210000002969 egg yolk Anatomy 0.000 abstract 2
- LRYZPFWEZHSTHD-HEFFAWAOSA-O 2-[[(e,2s,3r)-2-formamido-3-hydroxyoctadec-4-enoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium Chemical class CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](NC=O)COP(O)(=O)OCC[N+](C)(C)C LRYZPFWEZHSTHD-HEFFAWAOSA-O 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 230000005907 cancer growth Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000008105 phosphatidylcholines Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/688—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols both hydroxy compounds having nitrogen atoms, e.g. sphingomyelins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Se describen composiciones que implican un extracto de yema de huevo modificada para uso como un agente anti-cáncer efectivo. El extracto de yema de huevo modificada implica fracciones 5 específicas de fosfatidilcolinas y esfingomielinas modificadas y producidas de una síntesis química aplicada al extracto que produce un efecto benéfico en la inhibición del crecimiento de células cancerosas. También se describen métodos para administrar estas composiciones.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662356189P | 2016-06-29 | 2016-06-29 | |
| US201662356197P | 2016-06-29 | 2016-06-29 | |
| PCT/US2017/039894 WO2018005735A1 (en) | 2016-06-29 | 2017-06-29 | Phosopholipid compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018016091A true MX2018016091A (es) | 2019-09-16 |
Family
ID=60785317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018016091A MX2018016091A (es) | 2016-06-29 | 2017-06-29 | Composiciones de fosfolipidos. |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US10493086B2 (es) |
| EP (1) | EP3478296A4 (es) |
| JP (1) | JP2019520384A (es) |
| KR (1) | KR20190022796A (es) |
| CN (1) | CN109414446A (es) |
| AU (1) | AU2017290724A1 (es) |
| BR (1) | BR112018077350A2 (es) |
| CA (1) | CA3029419A1 (es) |
| IL (1) | IL263838A (es) |
| MX (1) | MX2018016091A (es) |
| RU (1) | RU2019102212A (es) |
| SG (1) | SG11201811776WA (es) |
| WO (1) | WO2018005735A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109946276B (zh) * | 2019-03-25 | 2021-04-30 | 遵义师范学院 | 一种双光子荧光探针的用途 |
| CN111454289A (zh) * | 2019-11-08 | 2020-07-28 | 苏州东南药业股份有限公司 | 一种二油酰磷脂酰胆碱的制备方法 |
| CN115364111B (zh) * | 2021-05-17 | 2024-04-02 | 中国医学科学院基础医学研究所 | 甘油磷脂类化合物在治疗肿瘤中的用途 |
| US20250152611A1 (en) * | 2022-01-19 | 2025-05-15 | President And Fellows Of Harvard College | Immunomodulatory lipids and uses thereof |
| CN114894910B (zh) * | 2022-03-18 | 2023-10-20 | 重庆医科大学附属第一医院 | 1-棕榈酰-2-花生四烯酰-sn-甘油-3-磷酸胆碱检测试剂的新用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US66354A (en) * | 1867-07-02 | Know all men by these presents | ||
| DE3777640D1 (es) | 1986-11-28 | 1992-04-23 | The Liposome Co.,Inc., Princeton, N.J., Us | |
| CZ280686B6 (cs) | 1992-04-07 | 1996-04-17 | Tomáš Vojkovský | N-acylované fosfolipidy typu 1-0-alkyl-sn-glycero -3-fosfoethanolaminů a způsob jejich semisyntetické přípravy a použití |
| US6602861B1 (en) | 1992-04-16 | 2003-08-05 | Research Corporation Technologies, Inc. | Acylated phospholipid drugs |
| CZ282139B6 (cs) | 1995-04-03 | 1997-05-14 | Jindřich Rndr. Drsc. Kára | Způsob výroby přípravku s dieteticko-preventivním a léčebným účinkem na bázi vaječných l-O-alkyl-2-acyl-fosfatidylethanolaminů |
| CN1516592A (zh) | 2001-06-18 | 2004-07-28 | �����Ǽ���&������Դ����˾ | 用于预防和/或治疗心血管疾病、关节炎、皮肤癌、糖尿病、经前综合症和透皮转运的磷虾和/或海产提取物 |
| EP1426053A1 (en) * | 2002-12-03 | 2004-06-09 | Fresenius Kabi Deutschland GmbH | Use of amphiphilic lipids for reducing tumor metastasis |
| CA2534241C (en) | 2003-07-31 | 2012-05-29 | The Board Of Regents Of The University Of Texas System | Compositions and methods for treating, preventing and/or ameliorating cancers, the onset of cancers or the symptoms of cancers |
| PL1871399T3 (pl) | 2005-04-18 | 2011-09-30 | Sc Dicophar | Zastosowanie lecytyny jako leku w leczeniu łuszczycy |
| WO2012088414A1 (en) * | 2010-12-23 | 2012-06-28 | Ludwig Institute For Cancer Research Ltd. | Liposomal formulation of nonglycosidic ceramides and uses thereof |
| PL217384B1 (pl) * | 2012-02-06 | 2014-07-31 | Univ Przyrodniczy We Wrocławiu | Nowa diacylo-sn-glicero-3-fosfocholina oraz sposób jej otrzymywania |
| WO2015104284A1 (en) * | 2014-01-08 | 2015-07-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for preventing or reducing metastatic dissemination |
-
2017
- 2017-06-29 KR KR1020197002656A patent/KR20190022796A/ko not_active Withdrawn
- 2017-06-29 EP EP17821214.8A patent/EP3478296A4/en not_active Withdrawn
- 2017-06-29 AU AU2017290724A patent/AU2017290724A1/en not_active Abandoned
- 2017-06-29 US US15/637,126 patent/US10493086B2/en active Active - Reinstated
- 2017-06-29 MX MX2018016091A patent/MX2018016091A/es unknown
- 2017-06-29 CN CN201780041147.7A patent/CN109414446A/zh active Pending
- 2017-06-29 CA CA3029419A patent/CA3029419A1/en not_active Abandoned
- 2017-06-29 SG SG11201811776WA patent/SG11201811776WA/en unknown
- 2017-06-29 WO PCT/US2017/039894 patent/WO2018005735A1/en not_active Ceased
- 2017-06-29 RU RU2019102212A patent/RU2019102212A/ru not_active Application Discontinuation
- 2017-06-29 JP JP2018569135A patent/JP2019520384A/ja active Pending
- 2017-06-29 BR BR112018077350-6A patent/BR112018077350A2/pt not_active Application Discontinuation
- 2017-10-06 US US15/727,075 patent/US20180028545A1/en not_active Abandoned
-
2018
- 2018-12-19 IL IL263838A patent/IL263838A/en unknown
-
2019
- 2019-10-15 US US16/653,591 patent/US11433085B2/en active Active
-
2022
- 2022-08-22 US US17/892,782 patent/US12263181B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2019102212A (ru) | 2020-07-29 |
| IL263838A (en) | 2019-01-31 |
| BR112018077350A2 (pt) | 2019-04-09 |
| US12263181B2 (en) | 2025-04-01 |
| WO2018005735A1 (en) | 2018-01-04 |
| AU2017290724A1 (en) | 2019-01-17 |
| US20220409641A1 (en) | 2022-12-29 |
| JP2019520384A (ja) | 2019-07-18 |
| WO2018005735A9 (en) | 2018-02-01 |
| EP3478296A1 (en) | 2019-05-08 |
| CA3029419A1 (en) | 2018-01-04 |
| US20180028545A1 (en) | 2018-02-01 |
| US20200046744A1 (en) | 2020-02-13 |
| CN109414446A (zh) | 2019-03-01 |
| KR20190022796A (ko) | 2019-03-06 |
| US10493086B2 (en) | 2019-12-03 |
| EP3478296A4 (en) | 2020-03-25 |
| US20180000850A1 (en) | 2018-01-04 |
| SG11201811776WA (en) | 2019-01-30 |
| US11433085B2 (en) | 2022-09-06 |
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