MX2018012739A - Acetil-leucina o una sal farmaceuticamente aceptable de la misma para mejorar la movilidad y funcion cognitiva. - Google Patents
Acetil-leucina o una sal farmaceuticamente aceptable de la misma para mejorar la movilidad y funcion cognitiva.Info
- Publication number
- MX2018012739A MX2018012739A MX2018012739A MX2018012739A MX2018012739A MX 2018012739 A MX2018012739 A MX 2018012739A MX 2018012739 A MX2018012739 A MX 2018012739A MX 2018012739 A MX2018012739 A MX 2018012739A MX 2018012739 A MX2018012739 A MX 2018012739A
- Authority
- MX
- Mexico
- Prior art keywords
- cognitive function
- leucine
- acetyl
- pharmaceutically acceptable
- acceptable salt
- Prior art date
Links
- 230000003920 cognitive function Effects 0.000 title abstract 3
- WXNXCEHXYPACJF-ZETCQYMHSA-N N-acetyl-L-leucine Chemical compound CC(C)C[C@@H](C(O)=O)NC(C)=O WXNXCEHXYPACJF-ZETCQYMHSA-N 0.000 title abstract 2
- 229960000669 acetylleucine Drugs 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 230000037230 mobility Effects 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente descripción está dirigida a acetilleucina o una sal farmacéuticamente aceptable de la misma para usarse en la mejora de la función cognitiva, movilidad o función cognitiva y movilidad en un sujeto, por ejemplo, en un sujeto anciano.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201606834 | 2016-04-19 | ||
| PCT/GB2017/051090 WO2017182802A1 (en) | 2016-04-19 | 2017-04-19 | Acetyl-leucine or a pharmaceutically acceptable salt thereof for improved mobility and cognitive function |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2018012739A true MX2018012739A (es) | 2019-06-17 |
| MX388461B MX388461B (es) | 2025-03-20 |
Family
ID=58633040
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018012739A MX388461B (es) | 2016-04-19 | 2017-04-19 | Acetil-leucina o una sal farmacéuticamente aceptable de la misma para mejorar la movilidad y función cognitiva. |
| MX2021014844A MX2021014844A (es) | 2016-04-19 | 2018-10-18 | Acetil-leucina o una sal farmaceuticamente aceptable de la misma para mejorar la movilidad y funcion cognitiva. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021014844A MX2021014844A (es) | 2016-04-19 | 2018-10-18 | Acetil-leucina o una sal farmaceuticamente aceptable de la misma para mejorar la movilidad y funcion cognitiva. |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US10905670B2 (es) |
| EP (2) | EP4501406A3 (es) |
| JP (3) | JP7387264B2 (es) |
| KR (4) | KR102632670B1 (es) |
| CN (2) | CN118593463A (es) |
| AU (2) | AU2017252507B2 (es) |
| BR (1) | BR112018071547A2 (es) |
| CA (1) | CA3021155A1 (es) |
| DK (1) | DK3445351T3 (es) |
| ES (1) | ES2994242T3 (es) |
| FI (1) | FI3445351T3 (es) |
| HR (1) | HRP20241552T1 (es) |
| HU (1) | HUE069219T2 (es) |
| IL (3) | IL262379B (es) |
| LT (1) | LT3445351T (es) |
| MD (1) | MD3445351T2 (es) |
| MX (2) | MX388461B (es) |
| NZ (1) | NZ747307A (es) |
| PL (1) | PL3445351T3 (es) |
| PT (1) | PT3445351T (es) |
| RS (1) | RS66142B1 (es) |
| RU (1) | RU2745912C2 (es) |
| SG (2) | SG10202106190RA (es) |
| SI (1) | SI3445351T1 (es) |
| SM (1) | SMT202400459T1 (es) |
| WO (1) | WO2017182802A1 (es) |
| ZA (1) | ZA201806849B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4501406A3 (en) * | 2016-04-19 | 2025-03-26 | IntraBio Ltd | Acetyl-leucine or a pharmaceutically acceptable salt thereof for improved mobility and cognitive function |
| LT3416631T (lt) | 2016-08-11 | 2019-08-26 | Intrabio Ltd | Terapiniai agentai, skirti neurodegeneracinių ligų gydymui |
| GB201709459D0 (en) | 2017-06-14 | 2017-07-26 | Intrabio Ltd | Treatment for migraine |
| CN113348018B (zh) | 2018-12-06 | 2025-04-01 | 内在生物技术有限公司 | 乙酰基-亮氨酸的氘代类似物 |
| IL321899A (en) * | 2019-03-02 | 2025-09-01 | Intrabio Ltd | Leucine, acetyl leucine and related analogs for the treatment of disease |
| WO2025019570A1 (en) * | 2023-07-18 | 2025-01-23 | Sytheon Ltd. | Novel amino acid based salts, compositions and methods for treating skin and rejuvenating skin and extending longevity |
| US12403111B2 (en) | 2024-02-02 | 2025-09-02 | SynGAP Research Fund | Compositions and methods for treating neurodevelopmental disorders |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060063827A1 (en) * | 2004-09-23 | 2006-03-23 | Yu Ruey J | Systemic administration of therapeutic amino acids and N-acetylamino acids |
| US20070190070A1 (en) * | 2004-09-03 | 2007-08-16 | Zeldis Jerome B | Methods of using and compositions comprising selective cytokine inhibitory drugs for the treatment and management of disorders of the central nervous system |
| FR2883180B1 (fr) * | 2005-03-18 | 2007-05-25 | Pierre Fabre Medicament Sa | Utilisation de l'acetyl-leucine pour la preparation d'un medicament destine au traitement de troubles de l'equilibre |
| FR2905600B1 (fr) * | 2006-09-13 | 2010-01-15 | Pf Medicament | Traitement des vertiges par l'acetyl-l-leucine. |
| US20080097606A1 (en) * | 2006-10-19 | 2008-04-24 | Cragg Andrew H | Knee joint prosthesis and hyaluronate compositions for treatment of osteoarthritis |
| CA2687107A1 (en) * | 2007-05-08 | 2008-11-13 | Northern Innovations And Formulations Corp. | Branched-chain amino acid composition for improving skeletal muscle protein metabolism |
| US20120196257A1 (en) * | 2009-08-27 | 2012-08-02 | Joe Verghese | Cognitive function training to improve motor ability |
| TN2010000251A1 (fr) * | 2010-06-03 | 2011-11-11 | Rekik Raouf | N-acetyl-dl-leucine medicament neuro et retino protecteur |
| WO2012060844A1 (en) * | 2010-11-05 | 2012-05-10 | Biotie Therapies, Inc | A2a antagonists as cognition and motor function enhancers |
| TN2010000566A1 (en) * | 2010-12-03 | 2012-05-24 | Rekik Raouf | Folic acid - ramipril combination : cell protective neuroprotective and retinoprotective ophtalmologic drugs |
| EP4501406A3 (en) * | 2016-04-19 | 2025-03-26 | IntraBio Ltd | Acetyl-leucine or a pharmaceutically acceptable salt thereof for improved mobility and cognitive function |
| US12458614B2 (en) * | 2017-10-18 | 2025-11-04 | Intrabio Ltd | Therapeutic agents for improved mobility and cognitive function and for treating neurodegenerative diseases and lysosomal storage disorders |
-
2017
- 2017-04-19 EP EP24205813.9A patent/EP4501406A3/en active Pending
- 2017-04-19 SG SG10202106190RA patent/SG10202106190RA/en unknown
- 2017-04-19 SI SI201731566T patent/SI3445351T1/sl unknown
- 2017-04-19 KR KR1020227021015A patent/KR102632670B1/ko active Active
- 2017-04-19 HR HRP20241552TT patent/HRP20241552T1/hr unknown
- 2017-04-19 KR KR1020187032983A patent/KR20180134398A/ko not_active Ceased
- 2017-04-19 KR KR1020227008412A patent/KR102413754B1/ko active Active
- 2017-04-19 IL IL262379A patent/IL262379B/en unknown
- 2017-04-19 HU HUE17719692A patent/HUE069219T2/hu unknown
- 2017-04-19 LT LTEPPCT/GB2017/051090T patent/LT3445351T/lt unknown
- 2017-04-19 WO PCT/GB2017/051090 patent/WO2017182802A1/en not_active Ceased
- 2017-04-19 JP JP2018555644A patent/JP7387264B2/ja active Active
- 2017-04-19 IL IL293266A patent/IL293266B2/en unknown
- 2017-04-19 MD MDE20190248T patent/MD3445351T2/ro unknown
- 2017-04-19 CA CA3021155A patent/CA3021155A1/en active Pending
- 2017-04-19 RS RS20241222A patent/RS66142B1/sr unknown
- 2017-04-19 MX MX2018012739A patent/MX388461B/es unknown
- 2017-04-19 US US16/093,780 patent/US10905670B2/en active Active
- 2017-04-19 KR KR1020247003393A patent/KR102791288B1/ko active Active
- 2017-04-19 RU RU2018140131A patent/RU2745912C2/ru active
- 2017-04-19 NZ NZ747307A patent/NZ747307A/en unknown
- 2017-04-19 PL PL17719692.0T patent/PL3445351T3/pl unknown
- 2017-04-19 ES ES17719692T patent/ES2994242T3/es active Active
- 2017-04-19 BR BR112018071547-6A patent/BR112018071547A2/pt not_active Application Discontinuation
- 2017-04-19 DK DK17719692.0T patent/DK3445351T3/da active
- 2017-04-19 EP EP17719692.0A patent/EP3445351B1/en active Active
- 2017-04-19 IL IL310508A patent/IL310508A/en unknown
- 2017-04-19 SM SM20240459T patent/SMT202400459T1/it unknown
- 2017-04-19 CN CN202410876111.2A patent/CN118593463A/zh active Pending
- 2017-04-19 AU AU2017252507A patent/AU2017252507B2/en active Active
- 2017-04-19 SG SG11201809031XA patent/SG11201809031XA/en unknown
- 2017-04-19 PT PT177196920T patent/PT3445351T/pt unknown
- 2017-04-19 FI FIEP17719692.0T patent/FI3445351T3/fi active
- 2017-04-19 CN CN201780029480.6A patent/CN109069463B/zh active Active
-
2018
- 2018-10-15 ZA ZA2018/06849A patent/ZA201806849B/en unknown
- 2018-10-18 MX MX2021014844A patent/MX2021014844A/es unknown
-
2020
- 2020-12-22 US US17/247,757 patent/US11998518B2/en active Active
-
2021
- 2021-11-12 JP JP2021185130A patent/JP7506046B2/ja active Active
-
2022
- 2022-10-17 AU AU2022256077A patent/AU2022256077A1/en not_active Abandoned
-
2023
- 2023-07-10 US US18/349,221 patent/US12329733B2/en active Active
-
2024
- 2024-06-13 JP JP2024096260A patent/JP2024123087A/ja active Pending
-
2025
- 2025-05-13 US US19/206,473 patent/US20250332133A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2018012739A (es) | Acetil-leucina o una sal farmaceuticamente aceptable de la misma para mejorar la movilidad y funcion cognitiva. | |
| IL269642A (en) | Methods and compositions for enhancing health | |
| CL2017003033A1 (es) | Dispositivo de monitorización para la aplicación de un fármaco con una pluma de fármaco, con registro, comunicación y alarmas. | |
| MX2018011216A (es) | Moléculas pequeñas contra cereblon para mejorar la función efectora de los linfocitos t. | |
| TWD172100S (zh) | 化粧瓶 | |
| TWD178500S (zh) | 護膚器 | |
| TWD169675S (zh) | 掛鉤 | |
| IL280809B (en) | Novel compositions, their use, and methods for their formation | |
| EP3414224A4 (en) | INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) | |
| TWD187490S (zh) | 病患連接裝置 | |
| CL2016001918A1 (es) | Heteroaril amidas como inhibidores de agregación de proteína | |
| TWD166031S (zh) | 口含物 | |
| MX2018012285A (es) | Metodos de tratamiento para enfermedades colestasicas y fibroticas. | |
| MX385447B (es) | Agente antihipertensivo | |
| IL268092B (en) | Tebipenem pivoxil crystalline forms, compositions including the same, methods of manufacture, and methods of use | |
| HUE055298T2 (hu) | Készítmények speciális tenzidekkel és nagy mennyiségekben glicerinnel | |
| TWD180565S (zh) | 塗抹器 | |
| EA201501130A1 (ru) | Офтальмологическая фармацевтическая композиция | |
| CL2018002930A1 (es) | (+)-azasetron para uso en el tratamiento de desórdenes de oído. | |
| TWD195659S (zh) | Washstand | |
| TWD176882S (zh) | 按摩裝置 | |
| TWD196366S (zh) | 包裝用容器 | |
| TWD170668S (zh) | 記事板 | |
| TWD184785S (zh) | 化妝品施用器 | |
| TWD179590S (zh) | 化妝品容器 |