MX2018011300A - Composiciones y metodos para el tratamiento de la presbicia. - Google Patents
Composiciones y metodos para el tratamiento de la presbicia.Info
- Publication number
- MX2018011300A MX2018011300A MX2018011300A MX2018011300A MX2018011300A MX 2018011300 A MX2018011300 A MX 2018011300A MX 2018011300 A MX2018011300 A MX 2018011300A MX 2018011300 A MX2018011300 A MX 2018011300A MX 2018011300 A MX2018011300 A MX 2018011300A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- presbyopia
- treatment
- methods
- preservative
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 201000010041 presbyopia Diseases 0.000 title abstract 2
- 229960003216 aceclidine Drugs 0.000 abstract 1
- WRJPSSPFHGNBMG-UHFFFAOYSA-N acetic acid 1-azabicyclo[2.2.2]octan-3-yl ester Chemical compound C1CC2C(OC(=O)C)CN1CC2 WRJPSSPFHGNBMG-UHFFFAOYSA-N 0.000 abstract 1
- 229940124570 cycloplegic agent Drugs 0.000 abstract 1
- 239000000634 cycloplegic agent Substances 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 239000003607 modifier Substances 0.000 abstract 1
- 229920005862 polyol Polymers 0.000 abstract 1
- 150000003077 polyols Chemical class 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
La invencion proporciona composiciones y metodos para el tratamiento de la presbicia y otros defectos de la vision; las composiciones comprenden preferiblemente aceclidina y un poliol y/o un agente cicloplejico; las composiciones contienen opcionalmente un agente tensoactivo, un potenciador de la viscosidad, un modificador de la osmolaridad y un conservador.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/073,089 US9844537B2 (en) | 2013-08-28 | 2016-03-17 | Compositions and methods for the treatment of presbyopia |
| US15/073,139 US9833441B2 (en) | 2013-08-28 | 2016-03-17 | Compositions and methods for the treatment of presbyopia |
| US15/235,431 US10052313B2 (en) | 2013-08-28 | 2016-08-12 | Compositions and methods for the treatment of presbyopia |
| PCT/US2017/021244 WO2017160548A1 (en) | 2016-03-17 | 2017-03-08 | Compositions and methods for the treatment of presbyopia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018011300A true MX2018011300A (es) | 2019-02-18 |
Family
ID=59852351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018011300A MX2018011300A (es) | 2016-03-17 | 2017-03-08 | Composiciones y metodos para el tratamiento de la presbicia. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP3429584A4 (es) |
| JP (1) | JP2019508472A (es) |
| CN (1) | CN108883102A (es) |
| CA (1) | CA3017755A1 (es) |
| MX (1) | MX2018011300A (es) |
| WO (1) | WO2017160548A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11026884B2 (en) * | 2018-01-24 | 2021-06-08 | Eye Therapies Llc | Methods for improving vision |
| WO2019204401A1 (en) * | 2018-04-19 | 2019-10-24 | Presbyopia Therapies Llc | Compositions and methods for the treatment of presbyopia |
| US11077053B2 (en) | 2018-08-21 | 2021-08-03 | Allergan, Inc. | Alpha-2-adrenergic receptor agonists for treatment of presbyopia, visual glare, visual starbursts, visual halos and night myopia |
| BR112021006618B1 (pt) * | 2018-10-10 | 2022-09-27 | Presbyopia Therapies, Inc | Composições e métodos para o tratamento da presbiopia |
| US20210251970A1 (en) | 2018-10-10 | 2021-08-19 | Presbyopia Therapies Inc | Compositions and methods for storage stable ophthalmic drugs |
| WO2021021644A1 (en) * | 2019-07-26 | 2021-02-04 | Allergan Sales, Llc | Compositions and methods for treatment of presbyopia |
| CA3195784A1 (en) * | 2020-11-02 | 2022-05-05 | Rhett Mead SCHIFFMAN | Degradant compound in a medicament |
| CN116583277A (zh) * | 2020-11-02 | 2023-08-11 | 视觉治疗股份有限公司 | 药物中的降解化合物 |
| CN118541148A (zh) | 2021-11-10 | 2024-08-23 | 视觉治疗股份有限公司 | 增强抗老花眼作用的碳酰胆碱制剂 |
| EP4433053A4 (en) | 2021-11-17 | 2025-09-17 | Lenz Therapeutics Operations Inc | ACECLIDINE DERIVATIVES, THEIR COMPOSITIONS AND METHODS OF USE |
| CN114588156B (zh) * | 2022-04-22 | 2024-06-11 | 温州医科大学附属眼视光医院 | 一种眼用制剂及其在治疗老花眼中的应用 |
| US12414942B1 (en) * | 2024-03-15 | 2025-09-16 | Lenz Therapeutics Operations, Inc. | Compositions, methods, and systems for treating presbyopia |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6120758A (en) * | 1998-07-16 | 2000-09-19 | Shaklee Corporation | Preservative system for topically applied products |
| US10064818B2 (en) * | 2013-08-28 | 2018-09-04 | Presbyopia Therapies, LLC | Compositions and methods for the treatment of presbyopia |
| US9314427B2 (en) * | 2013-08-28 | 2016-04-19 | Presbyopia Therapies Llc | Compositions and methods for the improvement of distance vision and the treatment of refractive errors of the eye |
| US10052313B2 (en) * | 2013-08-28 | 2018-08-21 | Presbyopia Therapies, LLC | Compositions and methods for the treatment of presbyopia |
| CA2934453A1 (en) * | 2013-12-18 | 2015-06-25 | Gnt, Llc | Compositions and methods for treatment of glaucoma |
-
2017
- 2017-03-08 WO PCT/US2017/021244 patent/WO2017160548A1/en not_active Ceased
- 2017-03-08 MX MX2018011300A patent/MX2018011300A/es unknown
- 2017-03-08 JP JP2018548865A patent/JP2019508472A/ja active Pending
- 2017-03-08 EP EP17767172.4A patent/EP3429584A4/en not_active Withdrawn
- 2017-03-08 CA CA3017755A patent/CA3017755A1/en not_active Abandoned
- 2017-03-08 CN CN201780017733.8A patent/CN108883102A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3017755A1 (en) | 2017-09-21 |
| WO2017160548A1 (en) | 2017-09-21 |
| CN108883102A (zh) | 2018-11-23 |
| EP3429584A4 (en) | 2019-11-13 |
| EP3429584A1 (en) | 2019-01-23 |
| JP2019508472A (ja) | 2019-03-28 |
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