[go: up one dir, main page]

MX2018010800A - Sistemas y metodos para la deteccion de alergenos. - Google Patents

Sistemas y metodos para la deteccion de alergenos.

Info

Publication number
MX2018010800A
MX2018010800A MX2018010800A MX2018010800A MX2018010800A MX 2018010800 A MX2018010800 A MX 2018010800A MX 2018010800 A MX2018010800 A MX 2018010800A MX 2018010800 A MX2018010800 A MX 2018010800A MX 2018010800 A MX2018010800 A MX 2018010800A
Authority
MX
Mexico
Prior art keywords
detection
sample
spns
allergens
methods
Prior art date
Application number
MX2018010800A
Other languages
English (en)
Inventor
Gilboa-Geffen Adi
Babu BROWN Renuka
Murphy Patrick
STIDHAM Sarah
Villareal Valerie
Glenn ANTHONY Joshua
H Kepler John
Jacobs Adam
J Young Adam
Original Assignee
Dots Tech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dots Tech Corp filed Critical Dots Tech Corp
Publication of MX2018010800A publication Critical patent/MX2018010800A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/02—Food
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C12M1/3446—Photometry, spectroscopy, laser technology
    • C12M1/3476—Fluorescence spectroscopy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14—Suction devices, e.g. pumps; Ejector devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G01N33/5304—Reaction vessels, e.g. agglutination plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/10—Applications; Uses in screening processes
    • C12N2320/11—Applications; Uses in screening processes for the determination of target sites, i.e. of active nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14—Suction devices, e.g. pumps; Ejector devices
    • G01N2001/1418—Depression, aspiration
    • G01N2001/1427—Positive displacement, piston, peristaltic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2866—Grinding or homogeneising

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Hydrology & Water Resources (AREA)
  • Optics & Photonics (AREA)
  • Sustainable Development (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

La presente invención proporciona sistemas, dispositivos, polinucleótidos de señalización (SPN, por sus siglas en inglés), agentes de detección y métodos para determinar la presencia o ausencia de uno o más alergenos en una muestra, particularmente una muestra de alimentos. El sistema de detección incluye un muestreador por separado, al menos un recipiente de detección desechable para la recepción y procesamiento de una muestra, así como dispositivo de detección para medir una señal de fluorescencia. Se proporcionan como agentes de detección, SPN derivados de aptámeros que se unen a los alergenos. Los SPN tienen una estructura única abierta y están marcados con un fluoróforo. Se miden los cambios en la polarización de fluorescencia de los SPN cuando se unen a los alergenos, con el fin de calcular el contenido de alergenos en una muestra.
MX2018010800A 2016-03-15 2017-03-10 Sistemas y metodos para la deteccion de alergenos. MX2018010800A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662308377P 2016-03-15 2016-03-15
US201662308376P 2016-03-15 2016-03-15
PCT/US2017/021737 WO2017160616A1 (en) 2016-03-15 2017-03-10 Systems and methods for allergen detection

Publications (1)

Publication Number Publication Date
MX2018010800A true MX2018010800A (es) 2018-11-09

Family

ID=59851843

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018010800A MX2018010800A (es) 2016-03-15 2017-03-10 Sistemas y metodos para la deteccion de alergenos.

Country Status (9)

Country Link
US (2) US10908139B2 (es)
EP (1) EP3429741A4 (es)
JP (1) JP2019511715A (es)
CN (1) CN108780027A (es)
AU (1) AU2017234548B2 (es)
CA (1) CA3013386A1 (es)
MX (1) MX2018010800A (es)
SG (1) SG11201806647VA (es)
WO (1) WO2017160616A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11591557B2 (en) 2017-02-21 2023-02-28 Dots Technology Corp. Systems for allergen detection
WO2019094968A1 (en) * 2017-11-13 2019-05-16 Base Pair Biotechnologies, Inc. Detection of tenofovir
TW201942574A (zh) 2018-02-21 2019-11-01 美商Ｄｏｔｓ科技公司 用於過敏原偵測的系統及方法
CA3107953A1 (en) * 2018-08-03 2020-02-06 Dots Technology Corp. Methods for aptamer selection
FR3098917B1 (fr) * 2019-07-17 2024-04-26 Commissariat Energie Atomique Procédé et système de détection d'un analyte présent dans un échantillon liquide
US12360022B2 (en) 2019-09-11 2025-07-15 Global Biyomedikal Saglik Hizmetleri Sanayi Ve Ticaret Limited Sirketi Tissue disaggregation, homogenization, photoactivation device
CA3152627A1 (en) * 2019-09-27 2021-04-01 Amandeep SANDHU Analyte detection method and device
US10927404B1 (en) * 2020-06-26 2021-02-23 4233999 Canada Inc. Pathogen detection using aptamer molecular beacons using a mobile device
US11053556B1 (en) * 2020-06-26 2021-07-06 4233999 Canada Inc. Pathogen detection using aptamer molecular photonic beacons using a mobile device
WO2021258210A1 (en) 2020-06-26 2021-12-30 4233999 Canada Inc. Pathogen detection using aptamer molecular photonic beacons
CN112414984B (zh) * 2020-11-06 2023-04-25 中国计量大学 便携式奶粉蛋白质含量检测盒
EP4247257A4 (en) * 2020-11-17 2025-01-08 Savr Pak Corporation Testing device, system, and methods for detecting contaminants
FR3128021B1 (fr) * 2021-10-12 2024-05-17 Univ Grenoble Alpes Procédé de détection d’un analyte cible dans un échantillon à l’aide de Bleu du Nil, composition pour la détection d’un analyte cible et son utilisation.
CN114075565B (zh) * 2022-01-19 2022-04-19 中国农业大学 一种用于检测β-乳球蛋白的双功能G-四链体变构生物传感器
JPWO2023190098A1 (es) * 2022-03-31 2023-10-05
CN114923974B (zh) * 2022-07-14 2022-10-04 深圳中食匠心食品有限公司 一种便携式面包重金属检测装置及其检测方法
US11782040B1 (en) * 2023-05-12 2023-10-10 Michele Glinn Cannabis potency testing method
CN116698680B (zh) * 2023-08-04 2023-09-29 天津创盾智能科技有限公司 一种生物气溶胶自动监测方法及系统
CN118068029B (zh) * 2024-04-22 2024-08-09 北京万泰生物药业股份有限公司 一种生物体样本快速检测装置

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5953251U (ja) * 1982-10-01 1984-04-07 日本甜菜製糖株式会社 試料採取管
US5166052A (en) * 1986-05-27 1992-11-24 Boris Cercek Method for measuring polarization of bathochromically shifted fluorescence
WO1998005962A1 (en) 1996-08-02 1998-02-12 Panvera Corporation A method for quantitating competitive binding of molecules to proteins utilizing fluorescence polarization
US6398402B1 (en) 1998-02-11 2002-06-04 Chris Thomas Disposable disruptor agitator tool having a bladed rotor disposed in a stator
US6032368A (en) * 1998-08-27 2000-03-07 The Pampered Chef, Ltd. Apple corer
FR2802640B1 (fr) * 1999-12-17 2003-01-03 Pasteur Sanofi Diagnostics Dispositif et procede de prelevement d'echantillon biologique
WO2001063260A1 (en) * 2000-02-25 2001-08-30 Cambridge Research & Instrumentation Inc. Instantaneous dual band fluorescence detection systems
WO2001083933A1 (en) * 2000-05-03 2001-11-08 Cybersonics, Inc. Smart-ultrasonic/sonic driller/corer
FI20031294A0 (fi) * 2003-09-10 2003-09-10 Thermo Labsystems Oy Fluorometrin kalibrointi
JP2005189341A (ja) * 2003-12-24 2005-07-14 Nisca Corp 画像読取装置
JP4427541B2 (ja) 2004-03-05 2010-03-10 プリマハム株式会社 乳アレルゲンの検出方法
WO2006010206A1 (en) * 2004-07-29 2006-02-02 Mnt Innovations Pty Ltd Biological saw sensor
ITTO20040743A1 (it) 2004-10-27 2005-01-27 Gianmarco Roggero Dispositivo omogeneizzatore monouso, e suo impiego per la preparazione di campioni omogeneizzati
JP4795765B2 (ja) * 2005-09-29 2011-10-19 シスメックス株式会社 試料処理装置
JP2007120976A (ja) * 2005-10-25 2007-05-17 Matsushita Electric Ind Co Ltd イムノアッセイ、およびそのキットとそのデバイス、それに使用する読取装置
AU2006335290A1 (en) * 2006-01-11 2007-07-19 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
BRPI0715823A2 (pt) * 2006-08-24 2013-07-16 Agency Science Tech & Res sistema de detecÇço àtica compacto
US20100285490A1 (en) 2006-12-29 2010-11-11 Invitrogen Corporation Detection apparatus
CA2702561A1 (en) * 2007-10-07 2009-04-16 Jordan Scott Portable device for detecting food allergens
JP4803561B2 (ja) * 2009-12-24 2011-10-26 独立行政法人土木研究所 簡易雪密度測定器
DE102010015964A1 (de) * 2010-03-15 2011-09-15 Leica Microsystems Cms Gmbh Vorrichtung und Verfahren zur multimodialen Bildgebung in der nichtlinearen Raman-Mikroskopie
WO2012078455A1 (en) * 2010-12-06 2012-06-14 Exploramed Iii, Inc. Allergen test kit
WO2012142623A2 (en) * 2011-04-15 2012-10-18 Aliment Health, Inc. Antigen detection system and methods of use
DE202012013668U1 (de) * 2011-06-02 2019-04-18 Raindance Technologies, Inc. Enzymquantifizierung
US8211715B1 (en) 2011-11-15 2012-07-03 Harrogate Holdings, Ltd. Co. Consumer food testing device providing remote monitoring
JP5970293B2 (ja) * 2012-08-21 2016-08-17 シスメックス株式会社 破砕処理装置
CA2888316C (en) * 2012-10-17 2021-05-04 Integrated Nano-Technologies, Llc Method and system for sample preparation
WO2014160861A1 (en) 2013-03-29 2014-10-02 6SensorLabs, Inc. A portable device for detection of harmful substances
CA3120508A1 (en) * 2013-10-28 2015-05-07 Dots Technology Corp. Allergen detection
CN105828947B (zh) 2013-12-20 2017-09-29 3M创新有限公司 用于样品浓缩和检测的系统和方法
JP6414907B2 (ja) * 2014-03-31 2018-10-31 Ｎｅｃソリューションイノベータ株式会社 そばアレルゲンに結合する核酸分子およびその用途
WO2016149253A1 (en) * 2015-03-16 2016-09-22 Dots Technology Corp. Portable allergen detection system

Also Published As

Publication number Publication date
CN108780027A (zh) 2018-11-09
US20190079063A1 (en) 2019-03-14
WO2017160616A1 (en) 2017-09-21
CA3013386A1 (en) 2017-09-21
US10908139B2 (en) 2021-02-02
JP2019511715A (ja) 2019-04-25
SG11201806647VA (en) 2018-09-27
EP3429741A1 (en) 2019-01-23
EP3429741A4 (en) 2019-11-27
AU2017234548A1 (en) 2018-08-30
AU2017234548B2 (en) 2021-03-25
US20210109076A1 (en) 2021-04-15

Similar Documents

Publication Publication Date Title
MX2018010800A (es) Sistemas y metodos para la deteccion de alergenos.
EP4365602A3 (en) Stomach cancer biomarker and detection method
EP4438743A3 (en) Pancreatic cancer detection kit or device, and detection method
NZ629703A (en) Methods and compositions for detecting multiple analytes with a single signal
HK1257991A1 (zh) 多重横向流动测量系统及其使用方法
EP4464797A3 (en) Kit, device, and method for detecting lung cancer
IN2014CN01970A (es)
EA201490999A1 (ru) Способ проведения количественных анализов
BR112016028944A2 (pt) kit ou dispositivo para a detecção de câncer do trato biliar e método de detecção
MX2021006791A (es) Metodos y composiciones para detectar proteinas mal plegadas.
BR112015019614A8 (pt) análise de imagens e medições de amostras biológicas
EP3816302A3 (en) Esophageal cancer detection kit or device, and detection method
IN2014KN02647A (es)
MX362703B (es) Clasificación de alto rendimiento de objetos pequeños a través del contenido de aceite y/o humedad usando resonancia magnética nuclear de campo bajo.
MX2015001961A (es) Metodos y sistemas para ensayos.
EP4498086A3 (en) Kit or device and method for detecting dementia
WO2016187159A3 (en) Methods and compositions for target detection in a nanopore using a labelled polymer scaffold
EP4570924A3 (en) Chromophore-based characterization and detection methods
EP4513499A3 (en) Method and device for analyzing target analyte in sample
MX371379B (es) Deteccion de la actividad de corte de una enzima.
GB201206977D0 (en) An enzyme detection device
EP3714276C0 (en) TEST SENSORS, SYSTEMS AND ANALYTICAL TECHNIQUES FOR MEASURING GLYCATED HEMOGLOBIN IN UNDILUTED BLOOD SAMPLES
HK1245060A1 (zh) 从生物样品的氧化还原电位测定生育力潜力
WO2015077382A3 (en) Combined cytology and molecular testing for early detection of esophageal adenocarcinoma
MX2017002795A (es) Metodo y dispositivo de prueba.