MX2018009990A - Metodos para mejorar la eficacia de una vacuna mediante la administracion de un antagonista il-4r. - Google Patents
Metodos para mejorar la eficacia de una vacuna mediante la administracion de un antagonista il-4r.Info
- Publication number
- MX2018009990A MX2018009990A MX2018009990A MX2018009990A MX2018009990A MX 2018009990 A MX2018009990 A MX 2018009990A MX 2018009990 A MX2018009990 A MX 2018009990A MX 2018009990 A MX2018009990 A MX 2018009990A MX 2018009990 A MX2018009990 A MX 2018009990A
- Authority
- MX
- Mexico
- Prior art keywords
- vaccine
- methods
- antagonist
- administering
- present
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 239000005557 antagonist Substances 0.000 title abstract 2
- 230000002708 enhancing effect Effects 0.000 title abstract 2
- 102000010787 Interleukin-4 Receptors Human genes 0.000 abstract 2
- 108010038486 Interleukin-4 Receptors Proteins 0.000 abstract 2
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 201000005702 Pertussis Diseases 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
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Abstract
La presente invención proporciona métodos para mejorar la eficacia y/o la seguridad de una vacuna. En algunas modalidades, la invención proporciona métodos para aumentar o potenciar la respuesta inmune a una vacuna en un paciente que lo necesita. Los métodos de la presente invención comprenden administrar a un paciente que lo necesita, un antagonista del receptor de interleucina-4 (IL-4R), tal como un anticuerpo anti-IL-$R en combinación con tal vacuna. En algunas modalidades, los métodos de la presente invención se usan para proporcionar protección mejorada a una enfermedad infecciosa, tal como la tos ferina.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662297257P | 2016-02-19 | 2016-02-19 | |
| US201662409936P | 2016-10-19 | 2016-10-19 | |
| PCT/US2017/018487 WO2017143270A1 (en) | 2016-02-19 | 2017-02-17 | Methods for enhancing efficacy of a vaccine by administering an il-4r antagonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018009990A true MX2018009990A (es) | 2018-12-17 |
Family
ID=58192407
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018009990A MX2018009990A (es) | 2016-02-19 | 2017-02-17 | Metodos para mejorar la eficacia de una vacuna mediante la administracion de un antagonista il-4r. |
| MX2024010676A MX2024010676A (es) | 2016-02-19 | 2018-08-17 | Metodos para mejorar la eficacia de una vacuna mediante el uso de un antagonista il-4r. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2024010676A MX2024010676A (es) | 2016-02-19 | 2018-08-17 | Metodos para mejorar la eficacia de una vacuna mediante el uso de un antagonista il-4r. |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US10314904B2 (es) |
| EP (2) | EP4420733A3 (es) |
| JP (3) | JP7597500B2 (es) |
| KR (1) | KR102868264B1 (es) |
| CN (1) | CN109069625A (es) |
| AU (2) | AU2017220184B2 (es) |
| CA (1) | CA3014202A1 (es) |
| ES (1) | ES2983475T3 (es) |
| HU (1) | HUE067673T2 (es) |
| IL (1) | IL261025A (es) |
| MA (1) | MA44238B1 (es) |
| MX (2) | MX2018009990A (es) |
| PL (1) | PL3416685T3 (es) |
| PT (1) | PT3416685T (es) |
| RU (1) | RU2753869C2 (es) |
| WO (1) | WO2017143270A1 (es) |
| ZA (1) | ZA201805295B (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| PT4011915T (pt) | 2012-08-21 | 2024-01-02 | Regeneron Pharma | Métodos para o tratamento ou prevenção da asma através da administração de um antagonista de il-4r |
| TWI697334B (zh) | 2013-06-04 | 2020-07-01 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| TWI682781B (zh) | 2013-07-11 | 2020-01-21 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法 |
| EP4353254A3 (en) | 2014-02-28 | 2024-07-03 | Regeneron Pharmaceuticals, Inc. | Methods for treating skin infection by administering an il-4r antagonist |
| WO2016077675A1 (en) | 2014-11-14 | 2016-05-19 | Sanofi Biotechnology | Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist |
| AU2017261687B2 (en) * | 2016-05-10 | 2023-10-19 | Hennepin Healthcare Research Institute | Cytokine signaling immunomodulators and methods |
| ES2994774T3 (en) * | 2016-09-01 | 2025-01-31 | Regeneron Pharma | Methods for preventing or treating allergy by administering an il-4r antagonist |
| US11053309B2 (en) | 2017-08-04 | 2021-07-06 | Regeneron Pharmaceuticals, Inc. | Methods for treating active eosinophilic esophagitis |
| MA46269B1 (fr) | 2017-08-18 | 2024-05-31 | Regeneron Pharma | Méthodes de traitement d'une dermatite atopique sévère par administration d'un inhibiteur des il-4r |
| PL3703818T3 (pl) | 2017-10-30 | 2024-03-25 | Sanofi Biotechnology | Antagonista IL-4R do zastosowania w sposobie leczenia lub zapobiegania astmie |
| KR20210010518A (ko) | 2018-05-13 | 2021-01-27 | 리제너론 파아마슈티컬스, 인크. | Il-4r 억제제를 투여하여 아토피성 피부염을 치료하는 방법 |
| WO2020092015A1 (en) | 2018-11-02 | 2020-05-07 | University Of Rochester | Therapeutic mitigation of epithelial infection |
| JP7548924B2 (ja) * | 2019-03-06 | 2024-09-10 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | がんの処置における増強された有効性のためのil-4/il-13経路阻害剤 |
| SG11202109002XA (en) | 2019-03-21 | 2021-09-29 | Regeneron Pharma | Combination of il-4/il-13 pathway inhibitors and plasma cell ablation for treating allergy |
| AU2020315369A1 (en) | 2019-07-16 | 2022-03-03 | Regeneron Pharmaceuticals, Inc. | Methods for treating or preventing asthma by administering an IL-4R antagonist |
| BR112022000377A2 (pt) | 2019-08-05 | 2022-05-10 | Regeneron Pharma | Métodos para o tratamento de dermatite atópica por administração de antagonista de il-4r |
| BR112022000581A2 (pt) | 2019-08-05 | 2022-03-03 | Regeneron Pharma | Métodos para tratamento de alergia e intensificação de imunoterapia específica dos alergénos através da administração de um antagonista de il-4r |
| EP4073810A1 (en) | 2019-12-09 | 2022-10-19 | Sanofi Biotechnology | Methods for treating digitally-identified il-4/il-13 related disorders |
| EP3992974A1 (en) | 2020-11-02 | 2022-05-04 | Sanofi Biotechnology | Methods for treating digitally-identified il-4/il-13 related disorders |
| JP2023520676A (ja) * | 2020-03-27 | 2023-05-18 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Il-4rアンタゴニストを投与することによりアトピー性皮膚炎を処置するための方法 |
| WO2023004420A1 (en) * | 2021-07-22 | 2023-01-26 | Icahn School Of Medicine At Mount Sinai | Dual-blockade of il-4 signaling and immune checkpoint proteins for treating cancer |
| WO2023028468A1 (en) * | 2021-08-23 | 2023-03-02 | Regeneron Pharmaceuticals, Inc. | Methods for treating atopic dermatitis by administering an il-4r antagonist |
| CN118717989A (zh) * | 2024-05-27 | 2024-10-01 | 中国人民解放军军事科学院军事医学研究院 | Il-4r拮抗剂在制备预防和/或治疗流感病毒感染的药物中的应用 |
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| EP2292665B1 (en) | 2000-05-26 | 2015-07-08 | Immunex Corporation | Use of interleukin-4 antibodies and compositions thereof |
| CA2462203A1 (en) * | 2001-10-12 | 2003-11-20 | University Of Iowa Research Foundation | Methods and products for enhancing immune responses using imidazoquinoline compounds |
| GB0217920D0 (en) * | 2002-04-23 | 2002-09-11 | Aventis Pharm Prod Inc | Interleukin-4 Gene Expression inhibitors |
| NZ547588A (en) | 2003-11-07 | 2009-05-31 | Immunex Corp | Antibodies that bind interleukin-4 receptor |
| WO2008054606A2 (en) | 2006-10-02 | 2008-05-08 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human il-4 receptor |
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| US8092804B2 (en) | 2007-12-21 | 2012-01-10 | Medimmune Limited | Binding members for interleukin-4 receptor alpha (IL-4Rα)-173 |
| CA2708871C (en) | 2007-12-21 | 2017-11-21 | Medimmune Limited | Binding members for interleukin-4 receptor alpha (il-4r.alpha.) - 173 |
| WO2010120524A2 (en) | 2009-03-31 | 2010-10-21 | Altair Therapeutics, Inc. | Methods of modulating an immune response to a viral infection |
| BR112013008366B1 (pt) | 2010-10-06 | 2022-02-08 | Regeneron Pharmaceuticals, Inc | Formulações farmacêuticas líquidas estáveis contendo anticorpos anti-receptor de interleucina-4 humana alfa, e recipiente contendo as referidas formulações |
| IN2014DN10408A (es) | 2012-06-05 | 2015-08-14 | Univ Australian | |
| EP3889181B1 (en) * | 2012-09-07 | 2024-04-24 | Regeneron Pharmaceuticals, Inc. | An il-4r antagonist antibody for use in treating atopic dermatitis by administering |
| TWI697334B (zh) | 2013-06-04 | 2020-07-01 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| CN105517570B (zh) | 2013-06-21 | 2020-04-07 | 赛诺菲生物技术公司 | 通过施用il-4r拮抗剂治疗鼻息肉症的方法 |
| US20210361700A1 (en) * | 2020-05-22 | 2021-11-25 | Trustees Of Tufts College | Nutritional supplement to combat covid-19 and aid vaccination |
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| RU2018133011A3 (es) | 2020-05-26 |
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| HUE067673T2 (hu) | 2024-11-28 |
| PT3416685T (pt) | 2024-07-25 |
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