MX2018008868A - Composiciones farmaceuticas que contienen glucomanano con liberacion extendida y propiedades disuasivas de abuso. - Google Patents
Composiciones farmaceuticas que contienen glucomanano con liberacion extendida y propiedades disuasivas de abuso.Info
- Publication number
- MX2018008868A MX2018008868A MX2018008868A MX2018008868A MX2018008868A MX 2018008868 A MX2018008868 A MX 2018008868A MX 2018008868 A MX2018008868 A MX 2018008868A MX 2018008868 A MX2018008868 A MX 2018008868A MX 2018008868 A MX2018008868 A MX 2018008868A
- Authority
- MX
- Mexico
- Prior art keywords
- extended release
- abuse deterrent
- pharmaceutical compositions
- containing pharmaceutical
- glucomannan
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- LUEWUZLMQUOBSB-FSKGGBMCSA-N (2s,3s,4s,5s,6r)-2-[(2r,3s,4r,5r,6s)-6-[(2r,3s,4r,5s,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5s,6r)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](OC3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-FSKGGBMCSA-N 0.000 title abstract 2
- 229920002581 Glucomannan Polymers 0.000 title abstract 2
- 238000013265 extended release Methods 0.000 title abstract 2
- 229940046240 glucomannan Drugs 0.000 title abstract 2
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 3
- 229920000233 poly(alkylene oxides) Polymers 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
Abstract
Una composición farmacéutica que comprende al menos un ingrediente farmacéuticamente activo (API, por sus siglas en inglés) o una sal farmacéuticamente aceptable de este, un glucomanano, un primer óxido de polialquileno que tiene un peso molecular promedio de no más de 300.000, y un segundo óxido de polialquileno que tiene un peso molecular promedio de al menos 1.000.000 y métodos para elaborarla. La composición farmacéutica proporciona liberación prolongada del API y tiene características disuasivas de abuso.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662292463P | 2016-02-08 | 2016-02-08 | |
| PCT/US2017/015235 WO2017139106A1 (en) | 2016-02-08 | 2017-01-27 | Glucomannan containing pharmaceutical compositions with extended release and abuse deterrent properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018008868A true MX2018008868A (es) | 2018-09-21 |
Family
ID=59497317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018008868A MX2018008868A (es) | 2016-02-08 | 2017-01-27 | Composiciones farmaceuticas que contienen glucomanano con liberacion extendida y propiedades disuasivas de abuso. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11065246B2 (es) |
| EP (1) | EP3413893A4 (es) |
| JP (1) | JP2019504072A (es) |
| AU (1) | AU2017216904B2 (es) |
| CA (1) | CA3013321A1 (es) |
| MX (1) | MX2018008868A (es) |
| WO (1) | WO2017139106A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017216904B2 (en) | 2016-02-08 | 2021-11-18 | SpecGx LLC | Glucomannan containing pharmaceutical compositions with extended release and abuse deterrent properties |
| IL273627B2 (en) | 2017-12-20 | 2025-03-01 | Purdue Pharma Lp | Morphine sulfate dosage forms for abuse deterrence |
| EP3911303A1 (en) * | 2019-01-18 | 2021-11-24 | Merck Patent GmbH | Method for manufacturing a solid administration form and solid administration form |
| CA3155766A1 (en) * | 2019-10-29 | 2021-05-06 | C. Chang I. Lee | Porous glucomannan scaffolds and methods for producing the scaffolds |
| CN112315924A (zh) * | 2020-11-10 | 2021-02-05 | 迪沙药业集团有限公司 | 一种阿奇霉素组合物及其制备方法 |
| JP7180941B1 (ja) | 2021-08-02 | 2022-11-30 | 株式会社創研 | 皮脂分泌抑制剤 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2065055A1 (en) | 1996-06-26 | 2009-06-03 | Board of Regents, The University of Texas System | Holt-melt extrudable pharmaceutical formulation |
| US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| AUPR839001A0 (en) | 2001-10-19 | 2001-11-15 | Eli Lilly And Company | Dosage form, device and methods of treatment |
| US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| WO2007112286A2 (en) | 2006-03-24 | 2007-10-04 | Auxilium Pharmaceuticals, Inc. | Stabilized compositions containing alkaline labile drugs |
| SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| ES2607209T3 (es) * | 2009-02-06 | 2017-03-29 | Egalet Ltd. | Composiciones farmacéuticas resistentes al abuso |
| CA2853764C (en) | 2011-11-22 | 2017-05-16 | Watson Pharmaceuticals, Inc. | Immediate release abuse deterrent tablet |
| ES2644935T3 (es) * | 2012-04-18 | 2017-12-01 | Mallinckrodt Llc | Composiciones farmacéuticas de liberación inmediata con propiedades disuasorias del abuso |
| WO2013158814A1 (en) | 2012-04-18 | 2013-10-24 | Mallinckrodt Llc | Immediate release, abuse deterrent pharmaceutical compositions |
| US9549899B2 (en) * | 2012-07-06 | 2017-01-24 | Egalet Ltd. | Abuse deterrent pharmaceutical compositions for controlled release |
| ES2698611T3 (es) | 2012-07-12 | 2019-02-05 | SpecGx LLC | Composiciones farmacéuticas disuasorias del abuso y de liberación prolongada |
| CA2791206A1 (en) | 2012-09-28 | 2014-03-28 | Pharmascience Inc. | Abuse deterrent pharmaceutical formulation |
| BR112015021002B8 (pt) | 2013-03-15 | 2023-03-28 | Mallinckrodt Llc | Forma de dosagem sólida farmacêutica compreendendo um ingrediente farmacêutico ativo |
| CA2817728A1 (en) * | 2013-05-31 | 2014-11-30 | Pharmascience Inc. | Abuse deterrent immediate release formulation |
| DK3164117T3 (da) * | 2014-07-03 | 2023-12-04 | SpecGx LLC | Misbrugssikre formuleringer med øjeblikkelig frigivelse omfattende ikke-cellulose-polysaccharider |
| AU2017216904B2 (en) | 2016-02-08 | 2021-11-18 | SpecGx LLC | Glucomannan containing pharmaceutical compositions with extended release and abuse deterrent properties |
-
2017
- 2017-01-27 AU AU2017216904A patent/AU2017216904B2/en active Active
- 2017-01-27 WO PCT/US2017/015235 patent/WO2017139106A1/en not_active Ceased
- 2017-01-27 EP EP17750563.3A patent/EP3413893A4/en not_active Withdrawn
- 2017-01-27 US US15/417,541 patent/US11065246B2/en active Active
- 2017-01-27 JP JP2018536818A patent/JP2019504072A/ja active Pending
- 2017-01-27 CA CA3013321A patent/CA3013321A1/en active Pending
- 2017-01-27 MX MX2018008868A patent/MX2018008868A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017216904B2 (en) | 2021-11-18 |
| CA3013321A1 (en) | 2017-08-17 |
| US20170224826A1 (en) | 2017-08-10 |
| US11065246B2 (en) | 2021-07-20 |
| EP3413893A1 (en) | 2018-12-19 |
| WO2017139106A1 (en) | 2017-08-17 |
| BR112018014839A2 (pt) | 2018-12-18 |
| EP3413893A4 (en) | 2019-08-28 |
| JP2019504072A (ja) | 2019-02-14 |
| AU2017216904A1 (en) | 2018-07-26 |
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