MX2018008469A - Metodos y dispositivos para tratar trastornos oculares posteriores con aflibercept y otros productos biologicos. - Google Patents
Metodos y dispositivos para tratar trastornos oculares posteriores con aflibercept y otros productos biologicos.Info
- Publication number
- MX2018008469A MX2018008469A MX2018008469A MX2018008469A MX2018008469A MX 2018008469 A MX2018008469 A MX 2018008469A MX 2018008469 A MX2018008469 A MX 2018008469A MX 2018008469 A MX2018008469 A MX 2018008469A MX 2018008469 A MX2018008469 A MX 2018008469A
- Authority
- MX
- Mexico
- Prior art keywords
- devices
- end portion
- methods
- medicament container
- disorderswith
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229960002833 aflibercept Drugs 0.000 title 1
- 108010081667 aflibercept Proteins 0.000 title 1
- 229960000074 biopharmaceutical Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 5
- 208000000208 Wet Macular Degeneration Diseases 0.000 abstract 3
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a métodos y dispositivos para tratar la AMD húmeda, CNV, AMD húmeda asociada con CNV y/o AMD húmeda asociada con RVO en un sujeto humano que lo necesite. En ciertos aspectos, los dispositivos que sé proporcionan en la presente incluyen un recipiente de medicamento que define un lumen configurado para contener un medicamento, una porción del extremo distante del recipiente de medicamento que incluye una porción de acoplamiento configurada para acoplarse de manera desmontable a un conjunto de aguja, una porción del extremo próximo del recipiente de medicamento que incluye una pestaña y un hombro longitudinal; un conjunto de pistón que incluye una porción del extremo distante dispuesta de manera móvil dentro del lumen del recipiente de medicamento; y un asa acoplada a una porción del extremo próximo del conjunto de pistón.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662276543P | 2016-01-08 | 2016-01-08 | |
| US201662324708P | 2016-04-19 | 2016-04-19 | |
| PCT/US2017/012757 WO2017120601A1 (en) | 2016-01-08 | 2017-01-09 | Methods and devices for treating posterior ocular disorderswith aflibercept and other biologics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018008469A true MX2018008469A (es) | 2018-11-09 |
Family
ID=59274052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018008469A MX2018008469A (es) | 2016-01-08 | 2017-01-09 | Metodos y dispositivos para tratar trastornos oculares posteriores con aflibercept y otros productos biologicos. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP3400014A1 (es) |
| JP (1) | JP2019501200A (es) |
| KR (1) | KR20180101488A (es) |
| CN (1) | CN108778330A (es) |
| AU (1) | AU2017206114A1 (es) |
| BR (1) | BR112018013805A2 (es) |
| CA (1) | CA3010862A1 (es) |
| MX (1) | MX2018008469A (es) |
| WO (1) | WO2017120601A1 (es) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
| CN106214321B (zh) | 2010-10-15 | 2018-08-28 | 科尼尔赛德生物医学公司 | 用于进入眼睛的装置 |
| EA034963B1 (ru) | 2012-11-08 | 2020-04-13 | Клиасайд Байомедикал, Инк. | Способ лечения расстройства заднего сегмента глаза |
| CN105246529B (zh) | 2013-05-03 | 2019-06-14 | 科尼尔赛德生物医学公司 | 用于眼部注射的设备和方法 |
| WO2014197317A1 (en) | 2013-06-03 | 2014-12-11 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
| US10273298B2 (en) | 2013-07-23 | 2019-04-30 | Novaliq Gmbh | Stabilized antibody compositions |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| CN110403923B (zh) | 2015-09-30 | 2021-09-21 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
| AU2016381964B2 (en) | 2015-12-30 | 2024-02-15 | Kodiak Sciences Inc. | Antibodies and conjugates thereof |
| IL262207B1 (en) | 2016-04-15 | 2025-09-01 | Univ Pennsylvania | Compositions for treatment of wet age-related macular degeneration |
| JP2019514581A (ja) | 2016-05-02 | 2019-06-06 | クリアサイド バイオメディカル,インコーポレイテッド | 眼の薬物送達のためのシステムおよび方法 |
| CN110177527B (zh) | 2016-08-12 | 2022-02-01 | 科尼尔赛德生物医学公司 | 用于调节药剂递送用针的插入深度的装置和方法 |
| US12090294B2 (en) | 2017-05-02 | 2024-09-17 | Georgia Tech Research Corporation | Targeted drug delivery methods using a microneedle |
| WO2019067540A1 (en) * | 2017-09-27 | 2019-04-04 | Regenxbio Inc. | TREATMENT OF OCULAR DISEASES WITH A TOTALLY HUMAN POST-TRANSLATIONAL MODIFICATION ANTI-VEGF FAB |
| AU2018388439B2 (en) * | 2017-12-20 | 2021-05-20 | Angex Pharmaceutical, Inc. | Carbamate and urea compounds as multikinase inhibitors |
| CN108030783A (zh) * | 2017-12-27 | 2018-05-15 | 广东众生药业股份有限公司 | 乐伐替尼在制备防治黄斑变性的药物中的用途 |
| CN112203679A (zh) | 2018-03-02 | 2021-01-08 | 科达制药股份有限公司 | Il-6抗体及其融合构建体和缀合物 |
| BR112020022610A2 (pt) * | 2018-05-10 | 2021-02-09 | Regeneron Pharmaceuticals, Inc. | proteína de fusão de receptor de vegf de alta concentração que contém formulações |
| CN110693886B (zh) * | 2018-07-09 | 2022-12-06 | 天津医科大学 | 防治脑海绵状血管畸形病变的药物 |
| FI3897595T3 (en) * | 2018-12-20 | 2023-03-31 | Thea Lab | NUTRITIONAL OPHTHALMIC COMPOSITION FOR THE TREATMENT OF RETINA DISEASES WITH A NEOVASCULAR COMPONENT |
| US12397039B2 (en) | 2019-02-13 | 2025-08-26 | Novaliq Gmbh | Compositions and methods for the treatment of ocular neovascularization |
| KR20200101160A (ko) * | 2019-02-19 | 2020-08-27 | 전남대학교산학협력단 | 리보세라닙을 포함하는 안구 신생혈관 억제용 약학 조성물 및 이를 이용한 안구 신생혈관 억제 방법 |
| CN113966236A (zh) * | 2019-04-03 | 2022-01-21 | 再生生物股份有限公司 | 眼睛病状的基因疗法 |
| CN110522909B (zh) * | 2019-09-30 | 2024-02-20 | 安徽省立医院 | 一种协同增强抗her2阳性肿瘤效果的药物组合 |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| AU2020383580A1 (en) * | 2019-11-11 | 2022-05-12 | Cstone Pharmaceuticals | Pharmaceutical combination and use thereof |
| IL293469B2 (en) * | 2019-12-19 | 2024-04-01 | Active Biotech Ab | Compounds for treatment of eye diseases associated with excessive vascularisation |
| CN119745879A (zh) * | 2020-02-19 | 2025-04-04 | 科尼尔赛德生物医学公司 | 包含阿西替尼的组合物和治疗眼部疾病的方法 |
| WO2021257193A1 (en) * | 2020-06-15 | 2021-12-23 | Opko Pharmaceuticals, Llc | Triamcinolone acetonide-loaded liposomes topical ophthalmic formulations as primary therapy for macular edema secondary to branch retinal vein occlusion |
| WO2022245739A1 (en) * | 2021-05-17 | 2022-11-24 | Regeneron Pharmaceuticals, Inc. | Extended, high dose vegf antagonist regimens for treatment of angiogenic eye disorders |
| CN113546176B (zh) * | 2021-06-30 | 2024-03-15 | 南通大学 | 一种特异性用于抑制眼内血管新生药物合成方法 |
| CN116087525B (zh) * | 2022-11-16 | 2025-10-28 | 东南大学 | 一种即时检测Tau蛋白的微腔结构高灵敏SERS芯片的制备方法 |
| CN118356501A (zh) * | 2023-01-19 | 2024-07-19 | 百奥泰生物制药股份有限公司 | 一种复方制剂及其应用 |
| WO2024167694A2 (en) * | 2023-02-06 | 2024-08-15 | Celularity Inc. | Placental extracellular matrices for ocular delivery of ophthalmic therapeutic agents |
| TW202515597A (zh) * | 2023-06-23 | 2025-04-16 | 美商再生元醫藥公司 | 用於血管新生眼睛病症之治療之延長高劑量vegf拮抗劑方案 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG194471A1 (en) * | 2011-05-27 | 2013-12-30 | Novartis Ag | Method of treating vision disorders |
| EP2817031A4 (en) * | 2012-02-22 | 2015-08-05 | Tufts College | COMPOSITIONS AND METHOD FOR THE ORGANIC ADMINISTRATION OF A THERAPEUTIC ACTIVE SUBSTANCE |
| EA034963B1 (ru) * | 2012-11-08 | 2020-04-13 | Клиасайд Байомедикал, Инк. | Способ лечения расстройства заднего сегмента глаза |
| WO2015095772A2 (en) * | 2013-12-20 | 2015-06-25 | Emory University | Formulations and methods for targeted ocular delivery of therapeutic agents |
| KR102511477B1 (ko) * | 2014-06-17 | 2023-03-16 | 클리어사이드 바이오메디컬, 인코포레이드 | 안구 후부 질환을 치료하기 위한 방법 및 디바이스 |
-
2017
- 2017-01-09 JP JP2018535400A patent/JP2019501200A/ja active Pending
- 2017-01-09 CA CA3010862A patent/CA3010862A1/en not_active Abandoned
- 2017-01-09 EP EP17736528.5A patent/EP3400014A1/en not_active Withdrawn
- 2017-01-09 BR BR112018013805-3A patent/BR112018013805A2/pt not_active Application Discontinuation
- 2017-01-09 AU AU2017206114A patent/AU2017206114A1/en not_active Abandoned
- 2017-01-09 WO PCT/US2017/012757 patent/WO2017120601A1/en not_active Ceased
- 2017-01-09 KR KR1020187022893A patent/KR20180101488A/ko not_active Withdrawn
- 2017-01-09 CN CN201780015406.9A patent/CN108778330A/zh active Pending
- 2017-01-09 MX MX2018008469A patent/MX2018008469A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20180101488A (ko) | 2018-09-12 |
| EP3400014A1 (en) | 2018-11-14 |
| WO2017120601A1 (en) | 2017-07-13 |
| BR112018013805A2 (pt) | 2018-12-11 |
| JP2019501200A (ja) | 2019-01-17 |
| AU2017206114A1 (en) | 2018-08-02 |
| CN108778330A (zh) | 2018-11-09 |
| CA3010862A1 (en) | 2017-07-13 |
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