MX2018006828A - Usos de poblaciones expandidas de celulas madre/progenitoras hematopoyeticas. - Google Patents
Usos de poblaciones expandidas de celulas madre/progenitoras hematopoyeticas.Info
- Publication number
- MX2018006828A MX2018006828A MX2018006828A MX2018006828A MX2018006828A MX 2018006828 A MX2018006828 A MX 2018006828A MX 2018006828 A MX2018006828 A MX 2018006828A MX 2018006828 A MX2018006828 A MX 2018006828A MX 2018006828 A MX2018006828 A MX 2018006828A
- Authority
- MX
- Mexico
- Prior art keywords
- progenitor cells
- hematopoietic stem
- reduce
- expanded populations
- following
- Prior art date
Links
- 210000003958 hematopoietic stem cell Anatomy 0.000 title abstract 2
- 210000000130 stem cell Anatomy 0.000 title abstract 2
- 208000009329 Graft vs Host Disease Diseases 0.000 abstract 2
- 208000024908 graft versus host disease Diseases 0.000 abstract 2
- 235000021476 total parenteral nutrition Nutrition 0.000 abstract 2
- 206010028116 Mucosal inflammation Diseases 0.000 abstract 1
- 201000010927 Mucositis Diseases 0.000 abstract 1
- 206010052779 Transplant rejections Diseases 0.000 abstract 1
- 230000000735 allogeneic effect Effects 0.000 abstract 1
- 210000004700 fetal blood Anatomy 0.000 abstract 1
- 230000006058 immune tolerance Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/12—Animals modified by administration of exogenous cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0381—Animal model for diseases of the hematopoietic system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se describen los usos de células madre/progenitoras hematopoyéticas (HSPC) de sangre de cordón expandidas. Ejemplos incluyen reducir el rechazo de trasplante, inducir inmunotolerancia, reducir la alimentación de nutrición parenteral total (TPN), el uso de opioides, la mucositis y la hospitalización después de un procedimiento médico y reducir la enfermedad de injerto versus huésped (GVHD) después de un trasplante alogénico.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562263573P | 2015-12-04 | 2015-12-04 | |
| US201562263470P | 2015-12-04 | 2015-12-04 | |
| PCT/US2016/064908 WO2017096347A1 (en) | 2015-12-04 | 2016-12-05 | Uses of expanded populations of hematopoietic stem/progenitor cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018006828A true MX2018006828A (es) | 2018-08-09 |
Family
ID=58797992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018006828A MX2018006828A (es) | 2015-12-04 | 2016-12-05 | Usos de poblaciones expandidas de celulas madre/progenitoras hematopoyeticas. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10813949B2 (es) |
| EP (1) | EP3384006A4 (es) |
| JP (2) | JP2018537472A (es) |
| KR (1) | KR20180085018A (es) |
| CN (1) | CN108473949A (es) |
| AU (1) | AU2016364934A1 (es) |
| BR (1) | BR112018011327A2 (es) |
| CA (1) | CA3005767A1 (es) |
| MX (1) | MX2018006828A (es) |
| RU (1) | RU2747728C2 (es) |
| WO (1) | WO2017096347A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110621321B (zh) | 2017-03-15 | 2024-06-21 | 浩康生物系统公司 | 用于造血干细胞移植的组合物和方法 |
| IL270678B2 (en) | 2017-05-16 | 2024-09-01 | Gamida Cell Ltd | Selection and use of umbilical cord cell fractions suitable for transplantation |
| CA3064055A1 (en) | 2017-05-16 | 2018-11-22 | Gamida-Cell Ltd. | Selection and use of umbilical cord cell fractions suitable for transplantation |
| US11697799B2 (en) | 2019-04-15 | 2023-07-11 | Ossium Health, Inc. | System and method for extraction and cryopreservation of bone marrow |
| CA3137570A1 (en) | 2019-05-15 | 2020-11-19 | Stemcyte Inc. | High concentration cell packaging and shipping |
| CN110564687B (zh) * | 2019-11-05 | 2020-04-03 | 诺未科技(北京)有限公司 | 用于扩增造血干细胞的组合物、培养基、方法和试剂盒 |
| EP4181675A4 (en) | 2020-07-18 | 2024-04-24 | Ossium Health, Inc. | PERMEATION OF WHOLE VERTEBRATE BODIES WITH A CRYOPRETECTIVE AGENT USING VACUUM-ASSISTED DIFFUSION |
| CN116583594B (zh) | 2020-10-14 | 2025-05-23 | 奥瑟姆健康公司 | 用于骨髓的提取和低温保藏的系统和方法 |
| WO2022133282A1 (en) | 2020-12-18 | 2022-06-23 | Ossium Health, Inc. | Methods of cell therapies |
| US20220323547A1 (en) * | 2021-04-13 | 2022-10-13 | Therapeutic Solutions International, Inc. | Amelioration and Treatment of Opioid Addiction |
| WO2023283404A1 (en) * | 2021-07-09 | 2023-01-12 | Temple University - Of The Commonwealth System Of Higher Education | Myocardial wound healing post ischemic injury |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5004681B1 (en) | 1987-11-12 | 2000-04-11 | Biocyte Corp | Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood |
| IE20030749A1 (en) | 1991-05-03 | 2003-11-12 | Indiana University Foundation | Human notch and delta binding domains in torporythmic proteins, and methods based thereon |
| IL101728A (en) | 1991-05-03 | 2007-08-19 | Univ Yale | Human Abandonment and Delta, Restrictive Areas of Effect in Tophoric Proteins, and Methods Based on Them |
| US5856441A (en) | 1991-05-03 | 1999-01-05 | Yale University | Serrate fragments and derivatives |
| US5869282A (en) | 1991-12-11 | 1999-02-09 | Imperial Cancer Research Technology, Ltd. | Nucleotide and protein sequences of the serrate gene and methods based thereon |
| WO1993012141A1 (en) | 1991-12-11 | 1993-06-24 | Yale University | Nucleotide and protein sequences of the serrate gene and methods based thereon |
| AU7404494A (en) | 1993-07-21 | 1995-02-20 | Cellpro, Incorporated | Methods and compositions for preventing immune rejection of solid organ grafts |
| AU4236296A (en) * | 1994-11-10 | 1996-06-06 | Fred Hutchinson Cancer Research Center | Intrathymic stem cell implantation |
| US5780300A (en) | 1995-09-29 | 1998-07-14 | Yale University | Manipulation of non-terminally differentiated cells using the notch pathway |
| US6544506B2 (en) * | 2000-01-05 | 2003-04-08 | Yeda Research & Development Co. Ltd. | Veto cells effective in preventing graft rejection and devoid of graft versus host potential |
| WO2002059285A1 (en) | 2000-10-27 | 2002-08-01 | Fred Hutchinson Cancer Research Center | Methods for immortalizing cells |
| US20020132343A1 (en) * | 2001-03-19 | 2002-09-19 | Clark Lum | System and method for delivering umbilical cord-derived tissue-matched stem cells for transplantation |
| US7147626B2 (en) | 2004-09-23 | 2006-12-12 | Celgene Corporation | Cord blood and placenta collection kit |
| CA2585343C (en) | 2004-10-25 | 2016-06-21 | Cellerant Therapeutics, Inc. | Methods of expanding myeloid cell populations and uses thereof |
| CN101421393B (zh) | 2006-02-14 | 2013-08-14 | 塞勒兰特治疗公司 | 提高造血干细胞植入的方法和组合物 |
| US20120269774A1 (en) | 2006-09-21 | 2012-10-25 | Medistem Laboratories, Inc | Allogeneic stem cell transplants in non-conditioned recipients |
| PT2120977E (pt) * | 2007-02-12 | 2013-09-16 | Anthrogenesis Corp | Tratamento de doenças inflamatórias utilizando células estaminais da placenta |
| CA3090548C (en) * | 2010-04-09 | 2025-09-02 | Fred Hutchinson Cancer Research Center | COMPOSITIONS AND METHODS FOR PROVIDING HEMATOPOIETIC FUNCTION |
| EP2555782A1 (en) * | 2010-04-09 | 2013-02-13 | Fred Hutchinson Cancer Research Center | Compositions and methods for providing hematopoietic function without hla matching |
| HK1203081A1 (en) * | 2011-12-08 | 2015-10-16 | Fred Hutchinson Cancer Research Center | Compositions and methods for enhanced generation of hematopoietic stem/progenitor cells |
| ES2811529T3 (es) * | 2011-12-22 | 2021-03-12 | Yeda Res & Dev | Una terapia de combinación para un injerto estable y a largo plazo usando protocolos específicos para el agotamiento de los linfocitos T/B |
| GB2502589B (en) | 2012-05-31 | 2019-09-11 | Denso Corp | Method for an in-vehicle apparatus, an in-vehicle apparatus and a vehicle |
| JP6361004B2 (ja) * | 2012-11-05 | 2018-07-25 | 株式会社レグイミューン | 免疫寛容誘導剤 |
-
2016
- 2016-12-05 AU AU2016364934A patent/AU2016364934A1/en not_active Abandoned
- 2016-12-05 MX MX2018006828A patent/MX2018006828A/es unknown
- 2016-12-05 US US15/781,447 patent/US10813949B2/en active Active
- 2016-12-05 JP JP2018528696A patent/JP2018537472A/ja active Pending
- 2016-12-05 RU RU2018124303A patent/RU2747728C2/ru active
- 2016-12-05 CA CA3005767A patent/CA3005767A1/en active Pending
- 2016-12-05 WO PCT/US2016/064908 patent/WO2017096347A1/en not_active Ceased
- 2016-12-05 CN CN201680078228.XA patent/CN108473949A/zh active Pending
- 2016-12-05 BR BR112018011327A patent/BR112018011327A2/pt not_active Application Discontinuation
- 2016-12-05 EP EP16871697.5A patent/EP3384006A4/en not_active Withdrawn
- 2016-12-05 KR KR1020187018203A patent/KR20180085018A/ko not_active Withdrawn
-
2022
- 2022-03-30 JP JP2022055176A patent/JP2022088551A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| RU2018124303A (ru) | 2020-01-13 |
| AU2016364934A1 (en) | 2018-06-07 |
| WO2017096347A1 (en) | 2017-06-08 |
| EP3384006A1 (en) | 2018-10-10 |
| BR112018011327A2 (pt) | 2018-12-04 |
| KR20180085018A (ko) | 2018-07-25 |
| US10813949B2 (en) | 2020-10-27 |
| JP2018537472A (ja) | 2018-12-20 |
| JP2022088551A (ja) | 2022-06-14 |
| EP3384006A4 (en) | 2019-06-12 |
| CA3005767A1 (en) | 2017-06-08 |
| RU2018124303A3 (es) | 2020-08-06 |
| RU2747728C2 (ru) | 2021-05-13 |
| US20180353541A1 (en) | 2018-12-13 |
| CN108473949A (zh) | 2018-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2018006828A (es) | Usos de poblaciones expandidas de celulas madre/progenitoras hematopoyeticas. | |
| MX2021014956A (es) | Formulaciones subcutaneas de anticuerpos anti-cd38 y sus usos. | |
| MX382102B (es) | Métodos mejorados para la elaboración de terapias celulares adoptivas. | |
| PH12014502767A1 (en) | Interleukin-2 fusion proteins and uses thereof | |
| IL275037A (en) | CRISPR-CAS9-modified CD34+ human hematopoietic stem and progenitor cells and uses thereof | |
| MX2015013590A (es) | Sistemas y metodos para la produccion dirigids de una proteina terapeutica dentro de una celula objetivo. | |
| PH12012502328A1 (en) | Methods for administering tube feed formulations | |
| MX2018002543A (es) | Composiciones que comprenden compuestos de urolitina. | |
| WO2015140648A3 (en) | Glycotargeting therapeutics | |
| BR112016024911A2 (pt) | composições de proteínas solúveis e métodos de sua produçâo | |
| MX2018008359A (es) | Sistemas y métodos para preparación de plaquetas. | |
| PH12016501705A1 (en) | Immunostimulatory plasmids | |
| SI3635096T1 (sl) | Metoda za izolacijo subpopulacij srčnih matičnih celic in povezane uporabe na medicinskem področju | |
| MY197524A (en) | System of multiple bags and method for the preparation of hemocomponents | |
| PH12016501689A1 (en) | Tatk-cdkl5 fusion proteins, compositions, formulations, and use thereof | |
| WO2015123493A3 (en) | Compositions and methods for modulatuion of immune response | |
| WO2014133728A3 (en) | Hhla2 as a novel inhibitor of human immune system and uses thereof | |
| IN2014DN08964A (es) | ||
| PH12017500018A1 (en) | Myo-inositol and probiotics, and their use | |
| PH12020550651A1 (en) | Gender specific synthetic nutritional compositions comprising lycopene and nutritional systems comprising them | |
| PH12018500164A1 (en) | Gender specific synthetic nutritional compositions and nutritional systems comprising them | |
| Bernardi et al. | Post-remission intensive treatment after induction chemotherapy is feasible in selected elderly patients with acute myeloid leukemia and age≥ 75 years: a retrospective analysis of the Rete Ematologica Lombarda | |
| PH12018500165A1 (en) | Gender specific synthetic nutritional compositions and nutritional systems comprising them | |
| EP3324735A4 (en) | Article of manufacture and methods for increasing survival of red blood cells | |
| HK1261108A1 (en) | Uses of expanded populations of hematopoietic stem/progenitor cells |