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MX2018004779A - Uso terapeutico de una solucion oftalmica acuosa esteril. - Google Patents

Uso terapeutico de una solucion oftalmica acuosa esteril.

Info

Publication number
MX2018004779A
MX2018004779A MX2018004779A MX2018004779A MX2018004779A MX 2018004779 A MX2018004779 A MX 2018004779A MX 2018004779 A MX2018004779 A MX 2018004779A MX 2018004779 A MX2018004779 A MX 2018004779A MX 2018004779 A MX2018004779 A MX 2018004779A
Authority
MX
Mexico
Prior art keywords
ophthalmic solution
therapeutic use
sterile
aquatic
acetylcysteinyl
Prior art date
Application number
MX2018004779A
Other languages
English (en)
Other versions
MX380088B (es
Inventor
Prinz Martin
Original Assignee
Croma Pharma Ges M B H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Croma Pharma Ges M B H filed Critical Croma Pharma Ges M B H
Publication of MX2018004779A publication Critical patent/MX2018004779A/es
Publication of MX380088B publication Critical patent/MX380088B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a una solución oftálmica acuosa estéril que comprende N-(N-acetilcisteinil)quitosano o una sal farmacéuticamente aceptable del mismo en una solución portadora, en donde el N-(N-acetilcisteinil)-quitosano tiene un contenido de grupos tiol libres en una cantidad de 80 µmol/ g de polímero a 280 µmol/g de polímero, para usar en el tratamiento de heridas de córnea.
MX2018004779A 2015-10-30 2016-10-27 Uso terapéutico de una solución oftálmica acuosa estéril. MX380088B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15192362 2015-10-30
PCT/EP2016/075939 WO2017072236A1 (en) 2015-10-30 2016-10-27 Therapeutic use of a sterile aqueous ophthalmic solution

Publications (2)

Publication Number Publication Date
MX2018004779A true MX2018004779A (es) 2018-06-19
MX380088B MX380088B (es) 2025-03-11

Family

ID=54476731

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018004779A MX380088B (es) 2015-10-30 2016-10-27 Uso terapéutico de una solución oftálmica acuosa estéril.

Country Status (15)

Country Link
US (1) US10583152B2 (es)
EP (1) EP3368007B1 (es)
JP (1) JP6817300B2 (es)
KR (1) KR20180066104A (es)
CN (1) CN108348455B (es)
AR (1) AR106494A1 (es)
BR (1) BR112018007686A2 (es)
CA (1) CA3001634C (es)
ES (1) ES2796361T3 (es)
IL (1) IL258785B (es)
MX (1) MX380088B (es)
PL (1) PL3368007T3 (es)
PT (1) PT3368007T (es)
RU (1) RU2741912C2 (es)
WO (1) WO2017072236A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3618803A1 (en) 2017-05-03 2020-03-11 Croma-Pharma GmbH Sterile aqueous ophthalmic solution containing n-(n-acetylcysteinyl)-chitosan for treating non-infectious corneal disorders
CN113318075B (zh) * 2021-06-24 2022-09-13 四川普锐特药业有限公司 一种乙酰半胱氨酸溶液及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1258781B (it) 1992-01-16 1996-02-29 Zambon Spa Composizione farmaceutica oftalmica contenente n-acetilcisteina e polivinilalcol
FR2692582B1 (fr) 1992-06-18 1998-09-18 Flamel Tech Sa Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux.
AT406054B (de) * 1998-11-04 2000-02-25 Andreas Bernkop-Schnuerch Verfahren zur verbesserung der mucoadhäsion von polymeren sowie deren herstellung und verwendung
GB2386900B (en) 2002-03-25 2006-11-01 Johnson & Johnson Medical Ltd Use in wound dressings of chemically modified polysaccharides
SI2107913T1 (sl) 2006-12-22 2012-05-31 Croma Pharma Ges M B H Uporaba tioliranih polisaharidov za tkivno avgmentacijo
KR20090108723A (ko) 2007-01-31 2009-10-16 알러간, 인코포레이티드 안 약물 송달을 위한 신규한 생체적합물질 및 이의 제조방법 및 용도
US9452592B2 (en) 2007-08-28 2016-09-27 Cryovac, Inc. Multilayer film having an active oxygen barrier layer with radiation enhanced active barrier properties
JP5297460B2 (ja) 2007-08-31 2013-09-25 デンツプライ インターナショナル インコーポレーテッド 三次元印刷方法および歯科用製品を製造するための材料
CN102065849B (zh) 2008-04-24 2015-04-29 麦德托尼克公司 基于壳聚糖和氧化多糖的保护性凝胶
CA2721938C (en) 2008-04-24 2016-08-09 Medtronic, Inc. Chitosan-containing protective composition
WO2009132226A1 (en) 2008-04-24 2009-10-29 Medtronic, Inc. Thiolated chitosan gel
EP2389939A1 (en) * 2010-05-28 2011-11-30 Novagali Pharma S.A. Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions
EP2555760B1 (en) * 2010-04-06 2019-10-16 Synedgen, Inc. Chitosan derivatives for the treatment of mucositis or ulceration
ITMI20120847A1 (it) * 2012-05-16 2013-11-17 Labomar S R L Formulazione per sostanze a bassa biodisponibilità.
ES2747808T3 (es) 2014-05-07 2020-03-11 Croma Pharma Ges M B H Solución oftálmica acuosa y método para tratar el síndrome del ojo seco

Also Published As

Publication number Publication date
CA3001634C (en) 2023-05-23
US20180303865A1 (en) 2018-10-25
PT3368007T (pt) 2020-06-17
CA3001634A1 (en) 2017-05-04
IL258785A (en) 2018-06-28
JP2018535962A (ja) 2018-12-06
WO2017072236A1 (en) 2017-05-04
RU2741912C2 (ru) 2021-01-29
MX380088B (es) 2025-03-11
EP3368007B1 (en) 2020-03-18
CN108348455B (zh) 2021-04-09
CN108348455A (zh) 2018-07-31
PL3368007T3 (pl) 2020-11-02
ES2796361T3 (es) 2020-11-26
RU2018119126A3 (es) 2020-02-14
RU2018119126A (ru) 2019-12-03
IL258785B (en) 2022-08-01
AR106494A1 (es) 2018-01-17
KR20180066104A (ko) 2018-06-18
BR112018007686A2 (pt) 2018-11-06
EP3368007A1 (en) 2018-09-05
JP6817300B2 (ja) 2021-01-20
US10583152B2 (en) 2020-03-10

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