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MX2018004515A - Agentes de anticuerpo especificos para cd19 humano y usos de los mismos. - Google Patents

Agentes de anticuerpo especificos para cd19 humano y usos de los mismos.

Info

Publication number
MX2018004515A
MX2018004515A MX2018004515A MX2018004515A MX2018004515A MX 2018004515 A MX2018004515 A MX 2018004515A MX 2018004515 A MX2018004515 A MX 2018004515A MX 2018004515 A MX2018004515 A MX 2018004515A MX 2018004515 A MX2018004515 A MX 2018004515A
Authority
MX
Mexico
Prior art keywords
human
antibody agents
agents specific
leukemia
prevention
Prior art date
Application number
MX2018004515A
Other languages
English (en)
Inventor
Liu Hong
Long Li
Cheng Neal
Lu Jingwei
Yang Zhiyuan
Original Assignee
Eureka Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eureka Therapeutics Inc filed Critical Eureka Therapeutics Inc
Publication of MX2018004515A publication Critical patent/MX2018004515A/es

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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39566—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against immunoglobulins, e.g. anti-idiotypic antibodies
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/70521—CD28, CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C12N5/0634—Cells from the blood or the immune system
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/522—CH1 domain
    • C—CHEMISTRY; METALLURGY
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    • C07K2319/00—Fusion polypeptide
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract

Se describen en el presente documento agentes de anticuerpo humano y agentes de unión multiespecíficos que se unen de manera específica al CD19 humano, en particular, al CD19 nativo humano. También se proporcionan en el presente documento métodos para utilizar los mismos o composiciones de los mismos para la detección, prevención y/o tratamiento terapéutico de enfermedades caracterizadas por la expresión de CD19, en particular, linfoma de las células B y leucemias.
MX2018004515A 2015-10-13 2016-10-11 Agentes de anticuerpo especificos para cd19 humano y usos de los mismos. MX2018004515A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562240624P 2015-10-13 2015-10-13
PCT/US2016/056325 WO2017066136A2 (en) 2015-10-13 2016-10-11 Antibody agents specific for human cd19 and uses thereof

Publications (1)

Publication Number Publication Date
MX2018004515A true MX2018004515A (es) 2019-04-15

Family

ID=58517819

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018004515A MX2018004515A (es) 2015-10-13 2016-10-11 Agentes de anticuerpo especificos para cd19 humano y usos de los mismos.

Country Status (14)

Country Link
US (2) US10301388B2 (es)
EP (1) EP3362479A4 (es)
JP (2) JP7017015B2 (es)
KR (1) KR102864524B1 (es)
CN (3) CN114470193B (es)
AU (2) AU2016339832B2 (es)
CA (1) CA3001910A1 (es)
IL (2) IL299203A (es)
MX (1) MX2018004515A (es)
MY (1) MY196631A (es)
PH (1) PH12018500810A1 (es)
SG (2) SG10201913902RA (es)
TW (1) TWI797065B (es)
WO (1) WO2017066136A2 (es)

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