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MX2018002705A - Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas. - Google Patents

Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas.

Info

Publication number
MX2018002705A
MX2018002705A MX2018002705A MX2018002705A MX2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A
Authority
MX
Mexico
Prior art keywords
yeast strains
secretion
expression
high temperatures
heterologous proteins
Prior art date
Application number
MX2018002705A
Other languages
English (en)
Inventor
Argyros Aaron
F Rice Charles
Skinner Ryan
Barrett Trisha
Original Assignee
Lallemand Hungary Liquidity Man Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lallemand Hungary Liquidity Man Llc filed Critical Lallemand Hungary Liquidity Man Llc
Publication of MX2018002705A publication Critical patent/MX2018002705A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C12N9/242—Fungal source
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001—Alpha-amylase (3.2.1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente descripción se refiere a cepas de levadura recombinante capaces de mantener su resistencia a temperatura elevada así como proteínas recombinantes expresadas a partir de esta. La presente descripción también proporciona métodos para utilizar la cepa de levadura recombinante para elaborar un producto de fermentación. La presente descripción procesa además un proceso para elaborar cepas de levadura recombinante capaces de mantener su resistencia a temperatura elevada.
MX2018002705A 2015-09-04 2016-08-29 Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas. MX2018002705A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562214412P 2015-09-04 2015-09-04
US201662299897P 2016-02-25 2016-02-25
PCT/IB2016/055162 WO2017037614A1 (en) 2015-09-04 2016-08-29 Yeast strains for the expression and secretion of heterologous proteins at high temperatures

Publications (1)

Publication Number Publication Date
MX2018002705A true MX2018002705A (es) 2018-12-19

Family

ID=56896745

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018002705A MX2018002705A (es) 2015-09-04 2016-08-29 Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas.

Country Status (7)

Country Link
US (1) US11332728B2 (es)
EP (1) EP3344762A1 (es)
CN (1) CN108291213A (es)
BR (1) BR112018004377A2 (es)
CA (1) CA2997380A1 (es)
MX (1) MX2018002705A (es)
WO (1) WO2017037614A1 (es)

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WO2018115513A1 (en) 2016-12-22 2018-06-28 Lallemand Hungary Liquidity Management Llc Sulfite tolerance in recombinant yeast host cells
EP3596208A1 (en) * 2017-03-13 2020-01-22 Lallemand Hungary Liquidity Management LLC Recombinant yeast host cells expressing cell-associated heterologous proteins
BR122022015725B1 (pt) 2017-05-23 2023-03-14 Lallemand Hungary Liquidity Management Llc Processo para a produção de um produto de fermentação
US20230091532A1 (en) * 2018-03-13 2023-03-23 Lallemand Hungary Liquidity Management Llc Inactivated yeast and yeast product for improving fermentation yield
EP3827088A1 (en) 2018-07-25 2021-06-02 Novozymes A/S Enzyme-expressing yeast for ethanol production
BR112021006692A2 (pt) 2018-10-08 2021-08-10 Novozymes A/S levedura expressando enzimas para produção de etanol
WO2020089847A1 (en) 2018-11-02 2020-05-07 Lallemand Hungary Liquidity Management Llc Process for preventing or limiting microbial contamination during continuous culture
WO2020100062A1 (en) 2018-11-13 2020-05-22 Lallemand Hungary Liquidity Management Llc Combined expression of trehalose producing and trehalose degrading enzymes
US20220228176A1 (en) 2018-11-13 2022-07-21 Lallemand Hungary Liquidity Management Llc Synergistic bacterial and yeast combinations
WO2020100069A1 (en) 2018-11-13 2020-05-22 Lallemand Hungary Liquidity Management Llc Modulation of formate oxidation by recombinant yeast host cell during fermentation
MX2021006660A (es) 2018-12-07 2021-07-07 Lallemand Hungary Liquidity Man Llc Modulacion de la generacion de nadph por medio de la celula hospedera de levadura recombinante durante la fermentacion.
CA3143527A1 (en) 2019-08-06 2021-02-11 Novozymes A/S Fusion proteins for improved enzyme expression
BR112022010434A2 (pt) 2019-11-29 2022-10-11 Lallemand Hungary Liquidity Man Llc Levedura que expressa glucoamilase heteróloga
WO2021104673A1 (en) * 2019-11-29 2021-06-03 Lallemand Hungary Liquidity Management Llc Process for displacing an exogenous enzyme
AU2020402990A1 (en) 2019-12-10 2022-06-09 Novozymes A/S Microorganism for improved pentose fermentation
MX2022009515A (es) 2020-02-10 2022-09-02 Novozymes As Variantes de alfa-amilasa y polinucleotidos que las codifican.
US20230235367A1 (en) 2020-02-10 2023-07-27 Novozymes A/S Process for producing ethanol from raw starch using alpha-amylase variants
US11999987B2 (en) 2020-03-19 2024-06-04 Lallemand Hungary Liquidity Management Llc Bacterial cocultures expressing a bacteriocin system
CA3112754A1 (en) 2020-03-19 2021-09-19 Lallemand Hungary Liquidity Management Llc Yeast expressing glucoamylase with enhanced starch hydrolysis
BR112022022797A2 (pt) 2020-05-11 2022-12-13 Lallemand Hungary Liquidity Man Llc Célula hospedeira de levedura recombinante que expressa uma hidrolase
US12448631B2 (en) 2020-07-10 2025-10-21 Danstar Ferment Ag Bacterial-derived nitrogen source for ethanol fermentation
CN112831485B (zh) * 2021-01-13 2023-08-15 云南师范大学 一种低温活性改良的外切菊粉酶突变体MutDR121EH9
CN116888142A (zh) 2021-01-26 2023-10-13 丹斯塔发酵股份公司 具有提高的生长速率的重组酵母宿主细胞
CN112662575B (zh) * 2021-01-28 2022-10-21 武汉轻工大学 高蛋白酶活性及高出酒率的扣囊复膜酵母菌、其组合物及应用
EP4352241A1 (en) 2021-06-07 2024-04-17 Novozymes A/S Engineered microorganism for improved ethanol fermentation
BR102022012055A2 (pt) 2021-06-17 2023-01-10 Lallemand Hungary Liquidity Management Llc Cepas de levedura exibindo persistência prolongada durante uma pluralidade de ciclos de fermentação
US20240409964A1 (en) 2021-10-11 2024-12-12 Danstar Ferment Ag Recombinant yeast cell having increased pyruvate decarboxylase activity
WO2024137704A2 (en) 2022-12-19 2024-06-27 Novozymes A/S Processes for producing fermentation products using fiber-degrading enzymes with engineered yeast
WO2024258820A2 (en) 2023-06-13 2024-12-19 Novozymes A/S Processes for producing fermentation products using engineered yeast expressing a beta-xylosidase
WO2025133860A1 (en) 2023-12-21 2025-06-26 Danstar Ferment Ag Increased production of acetyl-phosphate and products derived therefrom in yeasts
CN118703501B (zh) * 2024-08-27 2025-03-21 安琪酵母（滨州）有限公司 启动子及其在构建产麦角甾醇的酵母菌株中的应用

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BRPI0908308B1 (pt) * 2008-03-24 2021-01-12 Archer Daniels Midland Company. cepa h. polymorpha, e processo para a fabricação de etanol
CA2779163A1 (en) * 2009-12-30 2011-07-07 Iogen Energy Corporation Modified yeast strains exhibiting enhanced fermentation of lignocellulosic hydrolysates
EP2576762A4 (en) * 2010-06-03 2013-12-04 Mascoma Corp YEAST FOR THE EXPRESSION OF SACCHAROLYTIC ENZYMES FOR CONSOLIDATED BIOVERIC PROCESSING USING STARCH AND CELLULOSE
CN103649321B (zh) 2011-04-05 2019-07-16 拉勒曼德匈牙利流动性管理有限责任公司 用于通过添加交替电子受体改善微生物中的产品收率和产量的方法
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JP5878396B2 (ja) * 2012-03-02 2016-03-08 トヨタ自動車株式会社 新規プロモーター及びその利用
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Also Published As

Publication number Publication date
BR112018004377A2 (pt) 2019-04-09
WO2017037614A1 (en) 2017-03-09
US11332728B2 (en) 2022-05-17
CN108291213A (zh) 2018-07-17
US20180265853A1 (en) 2018-09-20
CA2997380A1 (en) 2017-03-09
EP3344762A1 (en) 2018-07-11

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