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MX2017015229A - Metodos para la cuantificacion espectrometrica de masas de analitos extraidos de un dispositivo de micromuestreo. - Google Patents

Metodos para la cuantificacion espectrometrica de masas de analitos extraidos de un dispositivo de micromuestreo.

Info

Publication number
MX2017015229A
MX2017015229A MX2017015229A MX2017015229A MX2017015229A MX 2017015229 A MX2017015229 A MX 2017015229A MX 2017015229 A MX2017015229 A MX 2017015229A MX 2017015229 A MX2017015229 A MX 2017015229A MX 2017015229 A MX2017015229 A MX 2017015229A
Authority
MX
Mexico
Prior art keywords
analyte
methods
amount
mass spectrometric
microsampling device
Prior art date
Application number
MX2017015229A
Other languages
English (en)
Inventor
Tran Diana
Goldman Scott
Goldman Mildred
EDINBORO Leslie
ADDISS Julia
WEBER Darren
MISTRY Porus
Clarke Nigel
Original Assignee
Quest Diagnostics Invest Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quest Diagnostics Invest Llc filed Critical Quest Diagnostics Invest Llc
Publication of MX2017015229A publication Critical patent/MX2017015229A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4055—Concentrating samples by solubility techniques
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8822—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Ecology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

Se describen métodos espectrométricos de masas para determinar la cantidad de un analito en una muestra recolectada por un dispositivo de micromuestreo. En el presente documento se proporcionan métodos dirigidos a la cuantificación de la cantidad de un analito en una muestra al extraer un analito de una muestra recolectada por un dispositivo de micromuestreo, purificar la muestra por cromatografía líquida, ionizar el analito para generar uno o más iones detectables por espectrometría de masas, y determinar la cantidad del o los iones por espectrometría de masas. La cantidad del analito en la muestra se relaciona con la cantidad del analito en el paciente.
MX2017015229A 2015-05-27 2016-05-27 Metodos para la cuantificacion espectrometrica de masas de analitos extraidos de un dispositivo de micromuestreo. MX2017015229A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562167164P 2015-05-27 2015-05-27
PCT/US2016/034815 WO2016191738A1 (en) 2015-05-27 2016-05-27 Methods for mass spectrometric quantitation of analytes extracted from a microsampling device

Publications (1)

Publication Number Publication Date
MX2017015229A true MX2017015229A (es) 2018-02-19

Family

ID=57393339

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017015229A MX2017015229A (es) 2015-05-27 2016-05-27 Metodos para la cuantificacion espectrometrica de masas de analitos extraidos de un dispositivo de micromuestreo.

Country Status (8)

Country Link
US (1) US20160349221A1 (es)
EP (1) EP3304064A4 (es)
JP (2) JP2018515796A (es)
CN (1) CN107850568A (es)
BR (1) BR112017025097B1 (es)
CA (1) CA2987323A1 (es)
MX (1) MX2017015229A (es)
WO (1) WO2016191738A1 (es)

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CN111879883A (zh) * 2019-11-15 2020-11-03 厦门市健康医疗大数据中心(厦门市医药研究所) 一种衍生化反应辅助富集家蚕或其制品中活性成分的检测方法
CN112964809A (zh) * 2019-12-13 2021-06-15 中国科学院大连化学物理研究所 一种检测生物体液多种类固醇激素试剂盒及其使用方法
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CN111537628B (zh) * 2020-04-15 2022-04-26 无锡微色谱生物科技有限公司 一种尿液中2-氯地西泮和4-氯地西泮的dpx-gc-ms检测方法
CN113281422B (zh) * 2020-12-11 2023-02-28 贵州省产品质量检验检测院 一种保健食品中14种镇静安神类非法添加物的测定方法
CN114646711B (zh) * 2020-12-21 2023-06-23 四川科瑞德制药股份有限公司 一种羟甲基苯妥英相关杂质的检测方法
WO2022133738A1 (zh) * 2020-12-22 2022-06-30 中山大学附属第一医院 一种术前鉴别甲状腺良恶性结节的生物标志物、试剂盒及其应用
CN112798710A (zh) * 2021-01-04 2021-05-14 浙江大学 一种检测人血浆左乙拉西坦浓度的hplc-uv方法
CN113267580B (zh) * 2021-05-18 2022-09-20 中南民族大学 一种监测地西泮血药浓度的方法
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Also Published As

Publication number Publication date
CA2987323A1 (en) 2016-12-01
US20160349221A1 (en) 2016-12-01
JP2021119346A (ja) 2021-08-12
CN107850568A (zh) 2018-03-27
EP3304064A4 (en) 2019-03-13
JP2018515796A (ja) 2018-06-14
EP3304064A1 (en) 2018-04-11
BR112017025097A2 (pt) 2019-04-24
WO2016191738A1 (en) 2016-12-01
BR112017025097B1 (pt) 2021-05-11

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