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MX2017009112A - Metodos y dispositivos de dispersion de polvo. - Google Patents

Metodos y dispositivos de dispersion de polvo.

Info

Publication number
MX2017009112A
MX2017009112A MX2017009112A MX2017009112A MX2017009112A MX 2017009112 A MX2017009112 A MX 2017009112A MX 2017009112 A MX2017009112 A MX 2017009112A MX 2017009112 A MX2017009112 A MX 2017009112A MX 2017009112 A MX2017009112 A MX 2017009112A
Authority
MX
Mexico
Prior art keywords
airflow
dispersion chamber
powdered medicament
diameter
inhaler includes
Prior art date
Application number
MX2017009112A
Other languages
English (en)
Inventor
Xu Zhen
m curtis Robert
Deaton Dan
Hannon James
Smyth Hugh
Donovan Martin
GIBBONS Aileen
Original Assignee
Respira Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Respira Therapeutics Inc filed Critical Respira Therapeutics Inc
Publication of MX2017009112A publication Critical patent/MX2017009112A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)

Abstract

Un inhalador de polvo seco incluye un elemento de almacenamiento de polvo configurado para contener un medicamento en polvo y un canal de entrada recibe el medicamento en polvo desde el elemento de almacenamiento de polvo que es arrastrado en un flujo de aire. El canal de entrada tiene un primer diámetro y define una abertura. El inhalador incluye una cámara de dispersión que recibe el flujo de aire y el medicamento en polvo desde la abertura. La cámara de dispersión tiene un segundo diámetro. El inhalador incluye un accionador alojado dentro de la cámara de dispersión. El accionador oscila dentro de la cámara de dispersión cuando se expone al flujo de aire para desagregar el medicamento en polvo arrastrado por el flujo de aire que pasa a través de la cámara de dispersión. Una relación entre el primer diámetro y el segundo diámetro está entre aproximadamente 0.40 y 0.60 tal que se produce un sonido audible a medida que oscila el accionador. El inhalador incluye un canal de salida a través del cual el flujo de aire y el medicamento en polvo salen del inhalador.
MX2017009112A 2015-01-14 2016-01-14 Metodos y dispositivos de dispersion de polvo. MX2017009112A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562103485P 2015-01-14 2015-01-14
PCT/US2016/013456 WO2016115379A1 (en) 2015-01-14 2016-01-14 Powder dispersion methods and devices

Publications (1)

Publication Number Publication Date
MX2017009112A true MX2017009112A (es) 2018-06-15

Family

ID=56366777

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017009112A MX2017009112A (es) 2015-01-14 2016-01-14 Metodos y dispositivos de dispersion de polvo.
MX2023006024A MX2023006024A (es) 2015-01-14 2017-07-11 Metodos y dispositivos de dispersion de polvo.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2023006024A MX2023006024A (es) 2015-01-14 2017-07-11 Metodos y dispositivos de dispersion de polvo.

Country Status (7)

Country Link
US (2) US10525216B2 (es)
EP (2) EP3244952A4 (es)
JP (1) JP2018501903A (es)
CN (1) CN107427650A (es)
CA (2) CA2972826C (es)
MX (2) MX2017009112A (es)
WO (1) WO2016115379A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10682476B2 (en) * 2012-02-21 2020-06-16 Respira Therapeutics, Inc. Powder inhaler, system and methods
EP3244952A4 (en) * 2015-01-14 2018-11-14 Respira Therapeutics, Inc. Powder dispersion methods and devices
US10118696B1 (en) 2016-03-31 2018-11-06 Steven M. Hoffberg Steerable rotating projectile
CN107753147A (zh) * 2016-08-18 2018-03-06 中国人民解放军军事医学科学院微生物流行病研究所 手持式干粉气溶胶肺递送装置
CA3039485A1 (en) * 2016-10-14 2018-04-19 Pulmatrix Operating Company, Inc. Antifungal dry powders
EP3612259B1 (en) * 2017-04-17 2022-11-09 Respira Therapeutics, Inc. Unit dose dry powder inhaler
CN114642275A (zh) * 2017-10-25 2022-06-21 菲利普莫里斯生产公司 用于吸入器制品和系统的刺穿附件
CN109821117B (zh) * 2017-11-23 2024-06-28 正大天晴药业集团股份有限公司 粉末释放装置及方法
WO2019101135A1 (zh) 2017-11-23 2019-05-31 正大天晴药业集团股份有限公司 新型干粉吸入装置
US11712637B1 (en) 2018-03-23 2023-08-01 Steven M. Hoffberg Steerable disk or ball
CN108671367A (zh) * 2018-05-22 2018-10-19 苏州市智水环境科研技术有限公司 一种水处理用探管式给药器
EP3979990A1 (en) 2019-06-10 2022-04-13 Respira Therapeutics, Inc. Carrier-based formulations and related methods
US10828432B1 (en) * 2019-06-24 2020-11-10 De Motu Cordis Pty Ltd Respiratory delivery device and method
US11793951B2 (en) 2019-06-24 2023-10-24 De Motu Cordis Pty Ltd Automatic dispenser for respiratory delivery device and method
US11717621B2 (en) 2019-06-24 2023-08-08 De Motu Cordis Pty Ltd Automatic dispenser for respiratory delivery device
WO2022049103A2 (en) * 2020-09-01 2022-03-10 Janssen Pharmaceutica Nv Drug delivery devices with reusable components and disposable components
CN120078994B (zh) * 2025-05-08 2025-07-08 四川省医学科学院·四川省人民医院 一种具有内置口含器分散单元的干粉药剂吸入器

Family Cites Families (262)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2603216A (en) 1952-07-15 Powder inhaler
US419942A (en) 1890-01-21 Insufflator
US16066A (en) 1856-11-11 Medical kespibatok
US361748A (en) 1887-04-26 John w
US376819A (en) 1888-01-24 Medicinal vapors
US263451A (en) 1882-08-29 adams
US598286A (en) 1898-02-01 Inhaler
US631621A (en) 1898-11-16 1899-08-22 James J Curran Inhaler.
US658436A (en) 1900-05-28 1900-09-25 Hans Hennerich Groth Insufflator.
US844097A (en) 1906-08-07 1907-02-12 Yancey Q Caldwell Inhaler.
US1599959A (en) 1923-03-23 1926-09-14 Fujimoto Buheiji Atomizer
US1752956A (en) 1927-04-21 1930-04-01 Karl Zeyen Apparatus for spraying pulverulent material
US2214032A (en) 1939-06-23 1940-09-10 Walter B Stewart Apparatus for administering powdered aluminum
US2513145A (en) 1946-11-27 1950-06-27 Charles C Chapple Inhaler
US2693805A (en) 1947-03-08 1954-11-09 George V Taplin Apparatus for administering therapeutic agents
US2470296A (en) 1948-04-30 1949-05-17 Abbott Lab Inhalator
US2642063A (en) 1948-07-31 1953-06-16 Frederick M Turnbull Inhaler
US2534636A (en) 1949-02-12 1950-12-19 American Cyanamid Co Powder dispenser
US2603215A (en) 1949-02-12 1952-07-15 American Cyanamid Co Drug inhalator
US2569720A (en) 1949-03-22 1951-10-02 Package Devices Inc Medicinal inhaler
US2641255A (en) 1949-03-31 1953-06-09 Abbott Lab Inhaler
US2517482A (en) 1949-04-09 1950-08-01 Sharp & Dohme Inc Inhaler
GB671582A (en) 1949-04-16 1952-05-07 Donald Herbert Brooks Improvements in dispensers for medicinal and other powders
US2549303A (en) 1949-04-20 1951-04-17 Bristol Lab Inc Inhaler for crystalline pencilllin or the like
US2587215A (en) 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US2579280A (en) * 1949-06-25 1951-12-18 Macgregor Instr Company Inhaler
US2573918A (en) 1949-11-05 1951-11-06 Vick Chemical Company Device for dispensing medicaments
US2581182A (en) 1950-03-14 1952-01-01 Abbott Lab Inhaler
GB705404A (en) 1950-05-19 1954-03-10 A M Bickford & Sons Ltd An inhaler for medicinal substances
US2992645A (en) 1958-05-06 1961-07-18 Benger Lab Ltd Disperser for powders
US3105488A (en) 1959-09-17 1963-10-01 Albert M Richards Respiratory devices
GB1182779A (en) 1966-09-17 1970-03-04 Fisons Pharmaceuticals Ltd Inhalation Device
GB1268051A (en) 1968-06-07 1972-03-22 Fisons Pharmaceuticals Ltd Inhalation device
IT941426B (it) 1971-07-17 1973-03-01 Isf Spa Inalatore a camera di turbinio per sostanze medicamentose polveriformi
US3888253A (en) * 1972-08-04 1975-06-10 Beecham Group Ltd Device for administration of medicines
GB1392945A (en) 1972-08-23 1975-05-07 Fisons Ltd Inhalation device
GB1459426A (en) 1973-02-26 1976-12-22 Allen & Hanburys Ltd Inhalation devices
FR2224175B1 (es) 1973-04-04 1978-04-14 Isf Spa
GB1387954A (en) 1973-05-08 1975-03-19 Miles Lab Insufflator
US3980074A (en) 1973-07-18 1976-09-14 Beecham Group Limited Device for the administration of powders
GB1479283A (en) 1973-07-23 1977-07-13 Bespak Industries Ltd Inhaler for powdered medicament
US3888252A (en) 1974-01-23 1975-06-10 Anthony J Side Powder inhaler
US3888262A (en) 1974-02-11 1975-06-10 Amf Inc Method and apparatus for finishing the ends of cigars
IT1016489B (it) * 1974-03-18 1977-05-30 Isf Spa Inalatore
US3971377A (en) * 1974-06-10 1976-07-27 Alza Corporation Medicament dispensing process for inhalation therapy
DE2525683A1 (de) 1974-06-12 1976-01-02 Ciba Geigy Ag Sulfogruppenhaltige heterocyclen
IT1017153B (it) 1974-07-15 1977-07-20 Isf Spa Apparecchio per inalazioni
US3964483A (en) 1975-01-13 1976-06-22 Syntex Puerto Rico, Inc. Inhalation device
US3948264A (en) 1975-05-21 1976-04-06 Mead Johnson & Company Inhalation device
GB1518998A (en) 1975-08-28 1978-07-26 Gillette Co Packaging flowable materials
US4147166A (en) 1977-05-02 1979-04-03 American Cyanamid Company Oral inhalator powder dispenser
US4216768A (en) 1978-03-23 1980-08-12 Whitfield Jack Device for inhaling powdered substance
IT1116047B (it) 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
BR8007911A (pt) 1979-12-06 1981-06-16 Glaxo Group Ltd Inalador aperfeicoado
ES506585A0 (es) 1980-10-30 1982-09-01 Riker Laboratories Inc Un dispositivo para facilitar la inhalacion oral de medica- mentos en forma de polvo
DE3274065D1 (de) 1981-07-08 1986-12-11 Draco Ab Powder inhalator
US4570630A (en) 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
GB2178965B (en) 1985-07-30 1988-08-03 Glaxo Group Ltd Devices for administering medicaments to patients
AT384552B (de) * 1985-08-01 1987-12-10 Hurka Wilhelm Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft
JPS62204756A (ja) 1986-03-04 1987-09-09 大研医工株式会社 薬剤揮散方法および装置
SE453566B (sv) 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
US4706663A (en) * 1986-04-25 1987-11-17 Makiej Paul A Particle catcher for inhalation devices
US5051917A (en) 1987-02-24 1991-09-24 International Business Machines Corporation Method of combining gate array and standard cell circuits on a common semiconductor chip
IT1228459B (it) * 1989-02-23 1991-06-19 Phidea S R L Inalatore con svuotamento regolare e completo della capsula.
DE69027319T2 (de) 1989-04-28 1996-11-21 Riker Laboratories Inc., Northridge, Calif. Inhalationsvorrichtung für trockenpulver
GB8909891D0 (en) 1989-04-28 1989-06-14 Riker Laboratories Inc Device
US5176132A (en) 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
US5239991A (en) 1989-06-21 1993-08-31 Fisons Plc Disposable powder medicament inhalation device with peel-off cover
IT1237118B (it) 1989-10-27 1993-05-18 Miat Spa Inalatore multidose per farmaci in polvere.
US5376386A (en) 1990-01-24 1994-12-27 British Technology Group Limited Aerosol carriers
US5201308A (en) 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
GB9004781D0 (en) 1990-03-02 1990-04-25 Glaxo Group Ltd Device
HU213221B (en) 1990-03-02 1997-03-28 Glaxo Group Ltd Inhalation device and medicine packet for device
US5615670A (en) 1990-03-07 1997-04-01 Fisons Plc Powder inhaler with centrifugal force used to meter powder
IL111254A (en) * 1990-06-14 1998-10-30 Rhone Poulenc Rorer Ltd Powder inhalers
GB9015522D0 (en) 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
DE4027390C2 (de) 1990-08-30 1994-11-03 Boehringer Ingelheim Kg Treibgasfreies Inhalationsgerät
US5429122A (en) 1990-09-26 1995-07-04 Zanen; Pieter Inhaler devices provided with a reservoir for several doses of medium for inhaling, transporting device, whirl chamber
GB9021433D0 (en) 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
US5042472A (en) 1990-10-15 1991-08-27 Merck & Co., Inc. Powder inhaler device
GB9024760D0 (en) 1990-11-14 1991-01-02 Riker Laboratories Inc Inhalation device and medicament carrier
GB9026025D0 (en) 1990-11-29 1991-01-16 Boehringer Ingelheim Kg Inhalation device
GB9027234D0 (en) 1990-12-15 1991-02-06 Harris Pharma Ltd An inhalation device
US5186164A (en) 1991-03-15 1993-02-16 Puthalath Raghuprasad Mist inhaler
US5225991A (en) 1991-04-11 1993-07-06 International Business Machines Corporation Optimized automated macro embedding for standard cell blocks
US5327883A (en) 1991-05-20 1994-07-12 Dura Pharmaceuticals, Inc. Apparatus for aerosolizing powdered medicine and process and using
FR2676929B1 (fr) 1991-05-30 1994-02-11 Aerosols Bouchage Ste Fse Inhalateur de poudres.
ES2284226T3 (es) 1991-07-02 2007-11-01 Nektar Therapeutics Dispositivo para proporcionar medicamentos en aerosol.
US5161524A (en) 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
DE69211450T2 (de) 1991-08-16 1996-12-05 Sandoz Ag Inhalator zur Verabreichung von pulverförmigen Substanzen
US5469843A (en) 1991-11-12 1995-11-28 Minnesota Mining And Manufacturing Company Inhalation device
US5349659A (en) 1992-01-23 1994-09-20 Cadence Design Systems, Inc. Hierarchical ordering of logical elements in the canonical mapping of net lists
US5476093A (en) 1992-02-14 1995-12-19 Huhtamaki Oy Device for more effective pulverization of a powdered inhalation medicament
EP0632734B1 (en) 1992-03-25 1998-06-10 Tebro S.A. Powder jet dispenser for medicament inhalation therapies
DE9307115U1 (de) 1992-05-29 1993-09-02 GGU Gesellschaft für Gesundheits- und Umweltforschung mbH & Co. Vertriebs KG, 65933 Frankfurt Vorrichtung zur Erzeugung inhalierbarer Wirkstoffe
US5394868A (en) 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
US5239993A (en) 1992-08-26 1993-08-31 Glaxo Inc. Dosage inhalator providing optimized compound inhalation trajectory
DK0659095T3 (da) 1992-09-11 1999-02-22 Glaxo Group Ltd Inhalator
PL173090B1 (pl) 1992-12-18 1998-01-30 Schering Corp Inhalator do sproszkowanych lekarstw
US5743250A (en) 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
IL108780A (en) 1993-02-27 1999-06-20 Fisons Plc Inhalation device
US5596742A (en) 1993-04-02 1997-01-21 Massachusetts Institute Of Technology Virtual interconnections for reconfigurable logic systems
US5437271A (en) 1993-04-06 1995-08-01 Minnesota Mining And Manufacturing Company Deagglomerators for dry powder inhalers
US5372128A (en) 1993-04-14 1994-12-13 Habley Medical Technology Corporation Fluidizing powder inhaler
US5533502A (en) 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
GB9312984D0 (en) 1993-06-23 1993-08-04 Bespak Plc Atomising dispenser
GB9314614D0 (en) 1993-07-14 1993-08-25 Minnesota Mining & Mfg Dry powder inhalers
US5349947A (en) 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
SE9302550D0 (sv) 1993-07-30 1993-07-30 Ernst Hoerlin Powder inhaler
US5388572A (en) 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
DE4340768A1 (de) 1993-11-30 1995-06-01 Bayer Ag Vorrichtung zum Inhalieren
US5415162A (en) 1994-01-18 1995-05-16 Glaxo Inc. Multi-dose dry powder inhalation device
PT101450B (pt) 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos Novo dispositivo para inalacao
US5526276A (en) 1994-04-21 1996-06-11 Quicklogic Corporation Select set-based technology mapping method and apparatus
GB9417399D0 (en) 1994-08-30 1994-10-19 Scherer Corp R P Ocular treatment device
KR970706032A (ko) 1994-09-16 1997-11-03 그라함 브레레턴 흡입 장치(Inhalation Device)
FR2725626A1 (fr) 1994-10-18 1996-04-19 Sofab Dispositif pour l'inhalation de produits en poudre
GB9422821D0 (en) 1994-11-11 1995-01-04 Aid Medic Ltd Atomizer
US5649165A (en) 1995-01-31 1997-07-15 Fujitsu Limited Topology-based computer-aided design system for digital circuits and method thereof
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
US5513630A (en) 1995-03-08 1996-05-07 Century; Theodore J. Powder dispenser
US5921237A (en) 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5622166A (en) 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5953519A (en) 1995-06-12 1999-09-14 Fura; David A. Method and system for generating electronic hardware simulation models
SE504458C2 (sv) 1995-06-21 1997-02-17 Lars Gunnar Nilsson Inhalator för elektrisk dosering av substanser
DE69617431T2 (de) 1995-06-21 2002-08-01 Asta Medica Ag Arzneipulverkartusche mit integrierter dosiereinrichtung, sowie pulverinhalator
GB9513218D0 (en) 1995-06-29 1995-09-06 Fisons Plc Inhalation device and method
DE19523516C1 (de) 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
US5642727A (en) 1995-07-25 1997-07-01 David Sarnoff Research Center, Inc. Inhaler apparatus using a tribo-electric charging technique
US6209538B1 (en) 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5692496A (en) 1995-08-02 1997-12-02 Innovative Devices, Llc Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5805462A (en) 1995-08-18 1998-09-08 Vlsi Technology, Inc. Automatic synthesis of integrated circuits employing boolean decomposition
US5617844A (en) 1995-09-21 1997-04-08 King; Russell W. Aerosol medication delivery system
US5712806A (en) 1995-10-30 1998-01-27 International Business Machines Corporation Optimized multiplexer structure for emulation systems
AU718682B2 (en) 1995-12-07 2000-04-20 Jagotec Ag Inhaler for multiple dosed administration of a pharmacological dry powder
US5669378A (en) 1995-12-21 1997-09-23 Pera; Ivo Inhaling device
PL327616A1 (en) 1996-01-03 1998-12-21 Glaxo Group Ltd Inhaler
US5694920A (en) 1996-01-25 1997-12-09 Abrams; Andrew L. Inhalation device
US6026809A (en) 1996-01-25 2000-02-22 Microdose Technologies, Inc. Inhalation device
US6470884B2 (en) * 1996-01-29 2002-10-29 Aventis Pharma Limited Capsule opening arrangement for use in a powder inhaler
US5699789A (en) 1996-03-11 1997-12-23 Hendricks; Mark R. Dry powder inhaler
JPH09253208A (ja) 1996-03-21 1997-09-30 Unisia Jecs Corp 鼻腔用投薬器
JP3328132B2 (ja) 1996-03-21 2002-09-24 株式会社ユニシアジェックス 吸入式投薬器
US5875776A (en) 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
US6123070A (en) 1996-06-07 2000-09-26 Valois S.A. Device for enhancing the emptying of an inhaler metering chamber
US5857456A (en) 1996-06-10 1999-01-12 Sarnoff Corporation Inhaler apparatus with an electronic means for enhanced release of dry powders
US5813401A (en) 1996-10-15 1998-09-29 Radcliff; Janet H. Nebulizer automatic control valve
US5987086A (en) 1996-11-01 1999-11-16 Motorola Inc. Automatic layout standard cell routing
SE9700421D0 (sv) 1997-02-07 1997-02-07 Astra Ab Single dose inhaler I
SE9700424D0 (sv) 1997-02-07 1997-02-07 Astra Ab Powder inhaler
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
ATE274956T1 (de) * 1997-05-27 2004-09-15 Direct Haler As Inhalator für pulverförmige medikamente
US6185719B1 (en) 1997-06-06 2001-02-06 Kawasaki Steel Corporation Pass-transistor logic circuit and a method of designing thereof
US6237590B1 (en) 1997-09-18 2001-05-29 Delsys Pharmaceutical Corporation Dry powder delivery system apparatus
US6237591B1 (en) 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
TR200002005T2 (tr) 1998-01-30 2000-11-21 Ig Spr�Htechnik Gmbh. Toz halindeki tıbbi uygulamada kullanılan ilaçların inhalasyonu için cihaz.
GB2334686B (en) 1998-02-26 2002-06-19 Medic Aid Ltd Nebuliser
GB9810126D0 (es) 1998-05-13 1998-07-08 Glaxo Group Ltd
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
US6152130A (en) 1998-06-12 2000-11-28 Microdose Technologies, Inc. Inhalation device with acoustic control
US6234169B1 (en) 1998-08-14 2001-05-22 Arthur Slutsky Inhaler
US6275973B1 (en) 1998-10-30 2001-08-14 Lsi Logic Corporation Integrated circuit design with delayed cell selection
DK1131059T3 (da) 1998-11-13 2003-06-30 Jago Res Ag Tørpulver til inhalation
US6282695B1 (en) 1998-12-16 2001-08-28 International Business Machines Corporation System and method for restructuring of logic circuitry
GB9905538D0 (en) 1999-03-10 1999-05-05 Glaxo Group Ltd A device
US6328033B1 (en) 1999-06-04 2001-12-11 Zohar Avrahami Powder inhaler
ITMI991582A1 (it) 1999-07-16 2001-01-16 Chiesi Farma Spa Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
JP3845530B2 (ja) * 1999-09-02 2006-11-15 株式会社日立製作所 吸入式投薬器
US6810872B1 (en) 1999-12-10 2004-11-02 Unisia Jecs Corporation Inhalant medicator
US6427688B1 (en) 2000-02-01 2002-08-06 Dura Pharmaceuticals, Icn. Dry powder inhaler
US7069929B2 (en) 2000-02-01 2006-07-04 Quadrant Technologies Limited Dry powder inhaler
US6971383B2 (en) 2001-01-24 2005-12-06 University Of North Carolina At Chapel Hill Dry powder inhaler devices, multi-dose dry powder drug packages, control systems, and associated methods
US6467074B1 (en) 2000-03-21 2002-10-15 Ammocore Technology, Inc. Integrated circuit architecture with standard blocks
FI20000810A0 (fi) 2000-04-06 2000-04-06 Orion Yhtymae Oyj Jauheinhalaattori
US6668827B2 (en) * 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
PE20020066A1 (es) 2000-06-23 2002-02-23 Norton Healthcare Ltd Deposito de dosis medidas previamente para inhalador de polvo seco accionado por la respiracion
US7225423B2 (en) 2000-06-30 2007-05-29 Zenasis Technologies, Inc. Method for automated design of integrated circuits with targeted quality objectives using dynamically generated building blocks
AU2001283546A1 (en) 2000-08-14 2002-02-25 Advanced Inhalation Research, Inc. Inhalation device and method
US20020087939A1 (en) 2000-09-06 2002-07-04 Greidinger Yaacov I. Method for designing large standard-cell based integrated circuits
SE517227C2 (sv) 2000-09-25 2002-05-14 Microdrug Ag Inhalator för torrt pulver med folieskärare
FI20002363A0 (fi) * 2000-10-27 2000-10-27 Orion Yhtymae Oyj Jauheinhalaattori
GB0026647D0 (en) 2000-10-31 2000-12-13 Glaxo Group Ltd Medicament dispenser
US6626173B2 (en) 2001-01-08 2003-09-30 Iep Pharmaceutical Devices Inc. Dry powder inhaler
FI20010538A0 (fi) * 2001-03-16 2001-03-16 Orion Corp Jauheinhalaattori
AUPR387701A0 (en) 2001-03-21 2001-04-12 Infamed Limited Improved spacer device
US6766799B2 (en) 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
KR20040023597A (ko) * 2001-05-10 2004-03-18 벡투라 딜리버리 디바이시스 리미티드 흡입기들
GB2375308A (en) 2001-05-10 2002-11-13 Cambridge Consultants Inhalers
SE0101825D0 (sv) 2001-05-22 2001-05-22 Astrazeneca Ab An Inhalation device
AU2002344835A1 (en) 2001-06-15 2003-01-02 Science And Technology Corporation @ Unm Digital circuits with selection operators
EG24184A (en) 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
DE10129703A1 (de) * 2001-06-22 2003-01-02 Sofotec Gmbh & Co Kg Zerstäubungssystem für eine Pulvermischung und Verfahren für Trockenpulverinhalatoren
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
US20040244794A1 (en) 2001-08-09 2004-12-09 Richards David Hugh Inhalation device with a pharmaceutical composition
GB0120018D0 (en) 2001-08-16 2001-10-10 Meridica Ltd Pack containing medicament and dispensing device
US20030042864A1 (en) 2001-08-31 2003-03-06 Delphi Technologies, Inc. Switched-reluctance motor control
US6779520B2 (en) 2001-10-30 2004-08-24 Iep Pharmaceutical Devices Inc. Breath actuated dry powder inhaler
ITMI20020078A1 (it) * 2002-01-16 2003-07-16 Fabrizio Niccolai Dispositivo utilizzabile nel tratamento di affezzioni delle vie respiratorie
GR1004350B (el) 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
US20030235538A1 (en) 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
SE524957C2 (sv) 2002-04-12 2004-11-02 Microdrug Ag Förfarande för uppdelning och fördelning i luft av torrt pulvermedikament
US7118010B2 (en) 2002-05-10 2006-10-10 Oriel Therapeutics, Inc. Apparatus, systems and related methods for dispensing and /or evaluating dry powders
US6889690B2 (en) 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
US6769436B2 (en) 2002-06-28 2004-08-03 Richard C. Horian Volatile inhaler and method
GB0217198D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
PT1386630E (pt) 2002-07-31 2006-09-29 Chiesi Farma Spa Inalador em po
CN1490061A (zh) * 2002-10-17 2004-04-21 北京万全阳光医药科技有限公司 一种新型的干粉药物吸入器
JP2004195191A (ja) 2002-10-22 2004-07-15 Akihiko Miyamoto 呼子付喘息治療薬吸入器
US7284553B2 (en) 2002-12-12 2007-10-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder inhaler comprising a chamber for a capsule for taking up a non-returnable capsule being filled with an active ingredient
US6941947B2 (en) * 2002-12-18 2005-09-13 Quadrant Technologies Limited Unit dose dry powder inhaler
US20040173211A1 (en) 2003-01-14 2004-09-09 Boehringer Ingelheim International Gmbh Powder inhaler
US20060254583A1 (en) 2003-03-20 2006-11-16 Arthur Deboeck Dry powder inhaler system
EP1488819A1 (en) 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Dry powder inhaler and method for pulmonary inhalation of dry powder
GB2405798A (en) 2003-09-15 2005-03-16 Vectura Ltd Dry powder inhaler with primary and secondary piercing elements and a medicament pack for use with an inhalation device.
DE10352277A1 (de) 2003-11-08 2005-06-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
JP2007522840A (ja) 2004-02-06 2007-08-16 マイクロドース・テクノロジーズ・インコーポレーテッド 吸入装置とともに用いられるブリスターパック
WO2005081977A2 (en) 2004-02-24 2005-09-09 Microdose Technologies, Inc. Directional flow sensor inhaler
US7556035B2 (en) 2004-05-28 2009-07-07 Quadrant Technologies Limited Unit dose dry powder inhaler
US8365725B2 (en) 2004-09-13 2013-02-05 Oriel Therapeutics, Inc. Dry powder inhalers that inhibit agglomeration, related devices and methods
CN101785892B (zh) * 2004-10-06 2014-12-10 贝林格尔·英格海姆国际有限公司 分配装置、存放装置以及分配粉末的方法
GB0427028D0 (en) 2004-12-09 2005-01-12 Cambridge Consultants Dry powder inhalers
GB0503738D0 (en) 2005-02-23 2005-03-30 Optinose As Powder delivery devices
GB0507711D0 (en) * 2005-04-15 2005-05-25 Vectura Group Plc Improved blister piercing
IL175664A0 (en) 2006-05-16 2006-09-05 Aespira Ltd Dry-powder inhaler
EP1795221A1 (en) 2005-12-02 2007-06-13 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
FR2895644B1 (fr) 2006-01-03 2008-05-16 Didier Gerard Martzel Substitut de cigarette
EP1986722B1 (en) 2006-01-31 2018-10-24 Oriel Therapeutics, Inc. Dry powder inhalers having spiral travel paths for microcartridges with dry powder
US8127763B2 (en) 2006-03-03 2012-03-06 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
EP1993645A4 (en) 2006-03-03 2011-05-18 Stc Unm DRY POWDER INHALER WITH AEROELASTIC SPREADING MECHANISM
US8037880B2 (en) 2006-04-07 2011-10-18 The University Of Western Ontario Dry powder inhaler
PT103481B (pt) 2006-05-16 2008-08-01 Hovione Farmaciencia S A Inalador de uso simples e método de inalação
JP2009543658A (ja) 2006-07-14 2009-12-10 アストラゼネカ・アクチエボラーグ 乾燥粉末状の薬を投与するための吸入装置及び配送装置
US20080035143A1 (en) 2006-08-14 2008-02-14 Sievers Robert E Human-powered dry powder inhaler and dry powder inhaler compositions
DE102006044756A1 (de) * 2006-09-20 2008-04-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DE102006044755A1 (de) 2006-09-20 2008-04-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
GB2456096B (en) * 2006-10-17 2011-08-17 Cipla Ltd Crystalline form of benzothiophene compound and process for preparation thereof
US8028695B2 (en) * 2006-11-30 2011-10-04 The General Electric Company Apparatus and system for reducing mechanical ventilator noise
US20090084379A1 (en) * 2007-10-02 2009-04-02 Baxter International Inc. Dry powder inhaler
EP2082764A1 (en) 2008-01-24 2009-07-29 Boehringer Ingelheim International GmbH Inhaler
GB0802028D0 (en) 2008-02-05 2008-03-12 Dunne Stephen T Powder inhaler flow regulator
DE102008014025A1 (de) 2008-03-13 2009-09-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator und Sieb für einen Inhalator
US20090235929A1 (en) 2008-03-19 2009-09-24 Marc Egen Powder inhalers
IL191190A0 (en) 2008-05-01 2009-08-03 Dan Adler Dry powder inhaler
CA3153292A1 (en) 2008-06-13 2009-12-17 Mannkind Corporation A dry powder inhaler and system for drug delivery
WO2010014827A2 (en) 2008-07-30 2010-02-04 Stc.Unm Formulations containing large-size carrier particles for dry powder inhalation aerosols
GB0818476D0 (en) * 2008-10-09 2008-11-12 Vectura Delivery Device Ltd Inhaler
CA2779488A1 (en) 2009-11-12 2011-05-19 Stc.Unm Dry powder inhaler with flutter dispersion member
US9056173B2 (en) 2010-01-27 2015-06-16 Aespira Ltd. Dry powder inhaler
JP5638826B2 (ja) * 2010-03-31 2014-12-10 株式会社吉野工業所 粉体吸入デバイス
CN101856531A (zh) * 2010-06-22 2010-10-13 于清 用于药物输送的高效干粉吸入器及其药物输送方法
EP2648788B1 (en) * 2010-12-07 2017-08-09 Respira Therapeutics, Inc. Dry powder inhaler
CN102553039B (zh) * 2010-12-17 2014-10-29 陈庆堂 药粉吸嘴及应用
CN102553040B (zh) * 2010-12-17 2014-07-02 陈庆堂 滤出药粉吸入器
US11103659B2 (en) * 2011-07-06 2021-08-31 Manta Devices, Llc Delivery device and related methods
WO2013016784A1 (en) * 2011-08-04 2013-02-07 Victor Esteve Dry powder inhaler
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
US10682476B2 (en) * 2012-02-21 2020-06-16 Respira Therapeutics, Inc. Powder inhaler, system and methods
FR3007992B1 (fr) 2013-07-05 2018-01-26 Aptar France Sas Dispositif de distribution de produit fluide ou pulverulent.
EP3244952A4 (en) 2015-01-14 2018-11-14 Respira Therapeutics, Inc. Powder dispersion methods and devices
EP3612259B1 (en) * 2017-04-17 2022-11-09 Respira Therapeutics, Inc. Unit dose dry powder inhaler

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EP3244952A1 (en) 2017-11-22
CA3206868A1 (en) 2016-07-21
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