[go: up one dir, main page]

MX2017008561A - Novedoso bacteriófago clo-pep-1 de clostridium perfringens y su uso para inhibir la proliferación de clostridium perfringens. - Google Patents

Novedoso bacteriófago clo-pep-1 de clostridium perfringens y su uso para inhibir la proliferación de clostridium perfringens.

Info

Publication number
MX2017008561A
MX2017008561A MX2017008561A MX2017008561A MX2017008561A MX 2017008561 A MX2017008561 A MX 2017008561A MX 2017008561 A MX2017008561 A MX 2017008561A MX 2017008561 A MX2017008561 A MX 2017008561A MX 2017008561 A MX2017008561 A MX 2017008561A
Authority
MX
Mexico
Prior art keywords
clostridium perfringens
pep
inhibiting proliferation
novel
bacteriophage
Prior art date
Application number
MX2017008561A
Other languages
English (en)
Other versions
MX383531B (es
Inventor
Soo Son Jee
Hwang PARK Suk
Youn Jun Soo
Hyeon KANG Sang
Jun Yoon Seong
Rok PAIK Hyoun
Original Assignee
Intron Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intron Biotechnology Inc filed Critical Intron Biotechnology Inc
Publication of MX2017008561A publication Critical patent/MX2017008561A/es
Publication of MX383531B publication Critical patent/MX383531B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/38—Other non-alcoholic beverages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F3/00—Biological treatment of water, waste water, or sewage
    • C02F3/34—Biological treatment of water, waste water, or sewage characterised by the microorganisms used
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10131—Uses of virus other than therapeutic or vaccine, e.g. disinfectant
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10171—Demonstrated in vivo effect

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Animal Husbandry (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Hydrology & Water Resources (AREA)
  • Environmental & Geological Engineering (AREA)
  • Water Supply & Treatment (AREA)

Abstract

La presente invención se refiere a un bacteriófago Myoviridae Clo-PEP-1 que se aísla de la naturaleza y puede destruir células de Clostridium perfringens específicamente, el cual tiene el genoma representado por la secuencia de nucleótidos de la sec. con núm. de ident.: 1 (número de registro en el KCTC 12664BP), y un método para prevenir y tratar las infecciones de células de Clostridium perfringens mediante el uso de la composición que comprende dicho bacteriófago como un ingrediente activo.
MX2017008561A 2014-12-29 2015-12-28 Novedoso bacteriófago clo-pep-1 de clostridium perfringens y su uso para inhibir la proliferación de clostridium perfringens MX383531B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020140191675A KR101649849B1 (ko) 2014-12-29 2014-12-29 신규한 클로스트리디움 퍼프린젠스 박테리오파지 Ｃｌｏ-ＰＥＰ-1 및 이의 클로스트리디움 퍼프린젠스 증식 억제 용도
PCT/KR2015/014326 WO2016108536A1 (ko) 2014-12-29 2015-12-28 신규한 클로스트리디움 퍼프린젠스 박테리오파지 Ｃｌｏ-ＰＥＰ-1 및 이의 클로스트리디움 퍼프린젠스 증식 억제 용도

Publications (2)

Publication Number Publication Date
MX2017008561A true MX2017008561A (es) 2017-10-26
MX383531B MX383531B (es) 2025-03-14

Family

ID=56284608

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017008561A MX383531B (es) 2014-12-29 2015-12-28 Novedoso bacteriófago clo-pep-1 de clostridium perfringens y su uso para inhibir la proliferación de clostridium perfringens

Country Status (8)

Country Link
US (1) US10028984B2 (es)
KR (1) KR101649849B1 (es)
CN (1) CN107109372B (es)
BR (1) BR112017013233A2 (es)
CO (1) CO2017006494A2 (es)
MX (1) MX383531B (es)
RU (1) RU2662986C1 (es)
WO (1) WO2016108536A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101761573B1 (ko) * 2014-12-29 2017-07-26 주식회사 인트론바이오테크놀로지 신규한 장출혈성 대장균 박테리오파지 Ｅｓｃ-ＣＨＰ-1 및 이의 장출혈성 대장균 증식 억제 용도
KR101649851B1 (ko) * 2014-12-30 2016-08-30 주식회사 인트론바이오테크놀로지 신규한 시가독소생산 F18형 대장균 박테리오파지 Ｅｓｃ-ＣＯＰ-1 및 이의 시가독소생산 F18형 대장균 증식 억제 용도
KR101761578B1 (ko) * 2014-12-30 2017-07-26 주식회사 인트론바이오테크놀로지 신규한 장병원성 대장균 박테리오파지 Ｅｓｃ-ＣＨＰ-2 및 이의 장병원성 대장균 증식 억제 용도
KR101761581B1 (ko) * 2014-12-30 2017-07-26 주식회사 인트론바이오테크놀로지 신규한 장침입성 대장균 박테리오파지 Ｅｓｃ-ＣＯＰ-4 및 이의 장침입성 대장균 증식 억제 용도
US11058131B2 (en) 2015-04-16 2021-07-13 Kennesaw State University Research And Service Foundation, Inc. Escherichia coli O157:H7 bacteriophage Φ241
KR102016920B1 (ko) * 2016-12-23 2019-09-02 주식회사 옵티팜 신규한 클로스트리디움 퍼프린젠스 특이 박테리오파지 cp5 및 이를 포함하는 항균 조성물
KR101993121B1 (ko) * 2016-12-23 2019-06-26 주식회사 옵티팜 신규한 클로스트리디움 퍼프린젠스 특이 박테리오파지 cp3 및 이를 포함하는 항균 조성물
KR101823860B1 (ko) 2017-02-24 2018-01-31 주식회사 인트론바이오테크놀로지 신규한 클로스트리디움 퍼프린젠스 박테리오파지 Clo-PEP-2 및 이의 클로스트리디움 퍼프린젠스 균 증식 억제 용도
KR102073088B1 (ko) * 2018-06-04 2020-02-04 (주)인트론바이오테크놀로지 신규한 스트렙토코커스 수이스 박테리오파지 Str-SUP-2 및 이의 스트렙토코커스 수이스 균 증식 억제 용도
KR102073086B1 (ko) * 2018-06-04 2020-02-04 (주)인트론바이오테크놀로지 신규한 스트렙토코커스 수이스 박테리오파지 Str-SUP-1 및 이의 스트렙토코커스 수이스 균 증식 억제 용도
KR102073094B1 (ko) * 2018-06-04 2020-02-04 (주)인트론바이오테크놀로지 신규한 스트렙토코커스 수이스 박테리오파지 Str-SUP-3 및 이의 스트렙토코커스 수이스 균 증식 억제 용도
CN110129279B (zh) * 2019-04-24 2022-02-18 昆明理工大学 一种粪肠球菌噬菌体及其分离、纯化、富集和应用
CN110628727B (zh) * 2019-10-12 2022-09-13 山东省农业科学院畜牧兽医研究所 一种新型产气荚膜梭菌噬菌体组合物及其应用
KR102305636B1 (ko) * 2019-10-28 2021-09-28 주식회사 인트론바이오테크놀로지 클로스트리디움 퍼프린젠스에 대하여 용균력을 가지는 신규한 항균단백질 cpel-1
CN111662880B (zh) * 2020-05-25 2022-06-17 江苏省农业科学院 一株产气荚膜梭菌噬菌体、包括噬菌体的抑菌剂及制备方法和应用
KR102586837B1 (ko) * 2021-02-23 2023-10-10 씨제이제일제당 주식회사 클로스트리디움 퍼프린젠스에 대한 특이적인 사멸능을 가지는 신규한 박테리오파지 및 이를 포함하는 항균 조성물
KR102586836B1 (ko) * 2021-02-23 2023-10-10 씨제이제일제당 주식회사 클로스트리디움 퍼프린젠스에 대한 특이적인 사멸능을 가지는 신규한 박테리오파지 및 이를 포함하는 항균 조성물
KR102586839B1 (ko) * 2021-02-25 2023-10-10 씨제이제일제당 주식회사 클로스트리디움 퍼프린젠스에 대한 특이적인 사멸능을 가지는 신규한 박테리오파지 및 이를 포함하는 항균 조성물
KR102586838B1 (ko) * 2021-02-25 2023-10-10 씨제이제일제당 주식회사 클로스트리디움 퍼프린젠스에 대한 특이적인 사멸능을 가지는 신규한 박테리오파지 및 이를 포함하는 항균 조성물
CN114621932B (zh) * 2021-05-20 2023-11-24 青岛诺安百特生物技术有限公司 一株新型魏氏梭菌噬菌体、包含该噬菌体的噬菌体组合物及其在兔魏氏梭菌病中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0202556D0 (en) * 2002-02-04 2002-03-20 Danisco Novel Protein
US7625739B2 (en) 2007-08-14 2009-12-01 Intralytix, Inc. Clostridium perfringens bacteriophage and uses thereof
KR20120076710A (ko) * 2010-12-30 2012-07-10 주식회사 인트론바이오테크놀로지 클로스트리디움 퍼프린젠스 특이 박테리오파지 ｃｐｐ-3
KR101381798B1 (ko) * 2013-02-27 2014-04-07 씨제이제일제당 (주) 신규 박테리오파지 및 이를 포함하는 항균 조성물
KR101381797B1 (ko) 2013-02-27 2014-04-07 씨제이제일제당 (주) 신규 박테리오파지 및 이를 포함하는 항균 조성물

Also Published As

Publication number Publication date
KR20160080175A (ko) 2016-07-07
CN107109372A (zh) 2017-08-29
CN107109372B (zh) 2020-09-11
WO2016108536A1 (ko) 2016-07-07
US10028984B2 (en) 2018-07-24
KR101649849B1 (ko) 2016-08-22
US20170340685A1 (en) 2017-11-30
MX383531B (es) 2025-03-14
BR112017013233A2 (pt) 2018-08-07
RU2662986C1 (ru) 2018-07-31
CO2017006494A2 (es) 2017-09-20

Similar Documents

Publication Publication Date Title
MX2017008561A (es) Novedoso bacteriófago clo-pep-1 de clostridium perfringens y su uso para inhibir la proliferación de clostridium perfringens.
CO2018006947A2 (es) Novedoso bacteriófago pas-mup-1 de pasteurella multocida y su uso para inhibir la proliferación de pasteurella multocida
MX2017008563A (es) Novedoso bacteriófago esc-cop-1 de e. coli tipo f18 productora de toxina shiga y su uso para inhibir la proliferación de e. coli tipo f18 productora de toxina shiga.
MX2022009148A (es) Composiciones y metodos para el tratamiento de hemoglobinopatias.
MX2017008562A (es) Novedoso bacteriófago de e. coli enteroinvasiva esc-cop-4 y su uso para inhibir la proliferación de e. coli enteroinvasiva.
MX2023003461A (es) Tratamiento de infeccion por clostridium difficile.
UY37360A (es) Nucleósidos sustituidos, nucleótidos y análogos de estos
MX2019009361A (es) Composiciones y metodos para el tratamiento de hemoglobinopatias.
MX2015007925A (es) Nucleosidos sustituidos, nucleotidos y analogos de los mismos.
CL2015002529A1 (es) Compuestos de tetrahidropirrolotiazina
BR112017013028A2 (pt) nucleosídeos, nucleotídeos e análogos dos mesmos substituídos
BR112016023851A2 (pt) ?composição de revestimento de duas partes e método para revestir uma superfície?
CL2016003277A1 (es) Métodos para preparar análogos de nucleótido sustituidos
BR112017000246A2 (pt) composto, sal farmaceuticamente aceitável de um composto, composição farmacêutica, e, uso de um composto ou de um sal
MX2018016037A (es) Variantes de lipasa y composiciones que comprenden tensioactivo y variante de lipasa.
CL2018001085A1 (es) Derivados de indolin-2-ona
MX2019009964A (es) Nuevo bacteriofago de clostridium perfringens clo-pep-2 y uso para inhibir la proliferacion de clostridium perfringens.
BR112016024096A2 (pt) novo bacteriófago e composição compreendendo o mesmo
PH12016502001A1 (en) Novel bacteriophage and composition comprising same
PE20170185A1 (es) Composiciones farmaceuticas para tratar enfermedades infecciosas
BR112017009289A2 (pt) métodos de administrar composições de amantadina
BR112019005886A2 (pt) tratamento com água de material lipídico
UY36217A (es) Compuestos piridona sustituídos, composiciones farmacéuticas y métodos de uso.
MX2017007380A (es) Compuestos organicos.
MX381255B (es) Vacunas contra el reovirus aviar.