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MX2016001023A - Formulaciones que contienen dapagliflozina amorfa. - Google Patents

Formulaciones que contienen dapagliflozina amorfa.

Info

Publication number
MX2016001023A
MX2016001023A MX2016001023A MX2016001023A MX2016001023A MX 2016001023 A MX2016001023 A MX 2016001023A MX 2016001023 A MX2016001023 A MX 2016001023A MX 2016001023 A MX2016001023 A MX 2016001023A MX 2016001023 A MX2016001023 A MX 2016001023A
Authority
MX
Mexico
Prior art keywords
pharmaceutical composition
solid dispersion
formulations containing
dapagliflozin
adsorbate
Prior art date
Application number
MX2016001023A
Other languages
English (en)
Other versions
MX370853B (es
Inventor
Rok Staric
Sandra Berglez
Jernej Grmas
Tinaja Stanic Ljubin
Rok Grahek
Luka Peternel
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of MX2016001023A publication Critical patent/MX2016001023A/es
Publication of MX370853B publication Critical patent/MX370853B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Mechanical Engineering (AREA)
  • Composite Materials (AREA)

Abstract

La presente invención pertenece al campo de la industria farmacéutica y se refiere a una dispersión sólida amorfa que comprende cuando menos un polímero y dapagliflozina, a una composición farmacéutica que comprende la dispersión sólida, a un proceso para la preparación de la misma, y a la dispersión sólida y la composición farmacéutica, respectivamente, que se pueden obtener mediante dicho proceso. Además, la presente invención se refiere a un adsorbato que comprende dapagliflozina y a una composición farmacéutica que comprende dicho adsorbato, así como a un proceso para la preparación de la misma. Finalmente, la presente invención se refiere a la dispersión sólida, el adsorbato o la composición farmacéutica, para utilizarse en el tratamiento de enfermedades relacionadas con hipoglucemia.
MX2016001023A 2013-07-22 2014-07-22 Formulaciones que contienen dapagliflozina amorfa. MX370853B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13177508 2013-07-22
PCT/EP2014/065661 WO2015011113A1 (en) 2013-07-22 2014-07-22 Formulations containing amorphous dapagliflozin

Publications (2)

Publication Number Publication Date
MX2016001023A true MX2016001023A (es) 2016-04-19
MX370853B MX370853B (es) 2020-01-08

Family

ID=48874149

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016001023A MX370853B (es) 2013-07-22 2014-07-22 Formulaciones que contienen dapagliflozina amorfa.

Country Status (12)

Country Link
US (2) US20160256433A1 (es)
EP (1) EP3024442B1 (es)
JP (2) JP6574417B2 (es)
KR (1) KR20160034348A (es)
CN (2) CN105555258A (es)
AU (2) AU2014295137B2 (es)
CA (1) CA2918570A1 (es)
ES (1) ES2721059T3 (es)
MX (1) MX370853B (es)
PT (1) PT3024442T (es)
TR (1) TR201905586T4 (es)
WO (1) WO2015011113A1 (es)

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WO2017042683A1 (en) * 2015-09-07 2017-03-16 Dr. Reddy's Laboratories Limited Isolated intermediate of dapagliflozin, process for the preparation of isolated intermediate of dapagliflozin, process for the preparation of dapagliflozin
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WO2017203229A1 (en) 2016-05-27 2017-11-30 Cipla Limited Dapagliflozin premixes
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KR102234154B1 (ko) * 2019-06-18 2021-03-31 삼천당제약주식회사 다파글리플로진비용매화물 함유 정제 제조방법 및 그에 의해 제조된 다파글리플로진비용매화물 함유 정제
US20220304936A1 (en) * 2019-08-28 2022-09-29 Lubrizol Advanced Materials, Inc. Drug-polymer amorphous solid dispersions using linear poly(acrylic acid) polymers
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EP4114365A1 (en) 2020-03-05 2023-01-11 KRKA, d.d., Novo mesto Pharmaceutical composition comprising sglt2 inhibitor
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Also Published As

Publication number Publication date
WO2015011113A1 (en) 2015-01-29
AU2014295137A1 (en) 2016-03-10
EP3024442B1 (en) 2019-01-16
US20190175543A1 (en) 2019-06-13
EP3024442A1 (en) 2016-06-01
MX370853B (es) 2020-01-08
CN108938583B (zh) 2021-05-04
CN108938583A (zh) 2018-12-07
CA2918570A1 (en) 2015-01-29
TR201905586T4 (tr) 2019-05-21
AU2014295137B2 (en) 2019-01-17
ES2721059T3 (es) 2019-07-26
CN105555258A (zh) 2016-05-04
AU2019200016A1 (en) 2019-01-24
JP2018184410A (ja) 2018-11-22
PT3024442T (pt) 2019-05-16
KR20160034348A (ko) 2016-03-29
JP2016525527A (ja) 2016-08-25
JP6574417B2 (ja) 2019-09-11
US20160256433A1 (en) 2016-09-08

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