MX2016000315A - Proceso para preparar fluoxastrobina. - Google Patents
Proceso para preparar fluoxastrobina.Info
- Publication number
- MX2016000315A MX2016000315A MX2016000315A MX2016000315A MX2016000315A MX 2016000315 A MX2016000315 A MX 2016000315A MX 2016000315 A MX2016000315 A MX 2016000315A MX 2016000315 A MX2016000315 A MX 2016000315A MX 2016000315 A MX2016000315 A MX 2016000315A
- Authority
- MX
- Mexico
- Prior art keywords
- methyl
- benzofuran
- reacting
- dioxazin
- dione
- Prior art date
Links
- 239000005784 Fluoxastrobin Substances 0.000 title abstract 3
- UFEODZBUAFNAEU-NLRVBDNBSA-N fluoxastrobin Chemical compound C=1C=CC=C(OC=2C(=C(OC=3C(=CC=CC=3)Cl)N=CN=2)F)C=1C(=N/OC)\C1=NOCCO1 UFEODZBUAFNAEU-NLRVBDNBSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- -1 alkyl nitrite Chemical compound 0.000 abstract 3
- NDYMQOUYJJXCKJ-UHFFFAOYSA-N (4-fluorophenyl)-morpholin-4-ylmethanone Chemical compound C1=CC(F)=CC=C1C(=O)N1CCOCC1 NDYMQOUYJJXCKJ-UHFFFAOYSA-N 0.000 abstract 2
- CKJNUZNMWOVDFN-UHFFFAOYSA-N methanone Chemical compound O=[CH-] CKJNUZNMWOVDFN-UHFFFAOYSA-N 0.000 abstract 2
- RKNNOQIDQDTNSB-UHFFFAOYSA-N n-methoxy-1-benzofuran-3-imine Chemical compound C1=CC=C2C(=NOC)COC2=C1 RKNNOQIDQDTNSB-UHFFFAOYSA-N 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- ISPYQTSUDJAMAB-UHFFFAOYSA-N 2-chlorophenol Chemical compound OC1=CC=CC=C1Cl ISPYQTSUDJAMAB-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C251/42—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
- C07D273/01—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having one nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
Abstract
Un proceso para preparar fluoxastrobina, incluyendo: (i) reaccionar benzofuran-3(2H)-ona O-metil oxima (10) con un nitrito de alquilo en presencia de un ácido para formar (3E)-2,3-benzofuran-diona O3-metil dioxima (11A) como un isómero predominante; (ii) reaccionar (3E)-2,3-benzofuran-diona O3-metil dioxima (11A) con 2-haloetanol para formar (3E)-benzofuran-2,3-dio na O2-(-hidroxietil) O3-metil dioxima (12A); y (iii) reaccionar (3E)-benzofuran-2,3-diona O2-(2-hidroetil) O3-metil dioxima (12A) con una base para formar (E)-(5,6-dihidro-1,4,2-dioxazin-3-il)(2-h idroxifenil)metanona O-metil oxima (13) (iv) reaccopmar ima 4, 6-di-halo-5-fluoro-pirimidina (5), en donde X1 es halógeno, con (E)-(5,6-dihidro-1,4,2-dioxazi n-3-il)(2-hidroxifenil)metanona O-metil oxima (13) en presencia de un solvente y opcionalmente en preencia de una base para formar una (E)-(2-((6-halo-5-fluoropirim idina-4-il)oxi)fenil)5,6-dihidro-1,4,2-dioxazin-3-il)metanona O-metil oxima (14): (v) reaccionar la (E)-2-((6halo-5-fluoropirimi dina-4-il)oxi)fenil)5,6-dihidro-1,4,2-dioxazin-3-il)metanona O-meti oxima (14) con 2-clorofeno en presencia de un solvente y opcionalmente en presencia de una base para formar fluoxastrobina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361843656P | 2013-07-08 | 2013-07-08 | |
| PCT/US2014/045556 WO2015006203A1 (en) | 2013-07-08 | 2014-07-07 | Process for preparing fluoxastrobin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016000315A true MX2016000315A (es) | 2016-11-14 |
| MX364158B MX364158B (es) | 2019-04-15 |
Family
ID=52133244
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019000836A MX368456B (es) | 2013-07-08 | 2014-07-07 | Proceso para preparar fluoxastrobina. |
| MX2016000315A MX364158B (es) | 2013-07-08 | 2014-07-07 | Proceso para preparar fluoxastrobina. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019000836A MX368456B (es) | 2013-07-08 | 2014-07-07 | Proceso para preparar fluoxastrobina. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9193698B2 (es) |
| EP (2) | EP3019495B1 (es) |
| CN (1) | CN105518003B (es) |
| AR (1) | AR100015A1 (es) |
| AU (1) | AU2014287480B2 (es) |
| BR (5) | BR122021013388B1 (es) |
| CA (1) | CA2917707C (es) |
| HU (1) | HUE051610T2 (es) |
| IL (1) | IL243455B (es) |
| MX (2) | MX368456B (es) |
| PL (1) | PL3019495T3 (es) |
| RU (1) | RU2653542C2 (es) |
| UA (1) | UA115093C2 (es) |
| WO (1) | WO2015006203A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3303312T3 (pl) * | 2015-05-29 | 2024-06-17 | Arysta Lifescience Corporation | Sposób otrzymywania o-metylooksymu (e)-(5,6-dihydro-1,4,2-dioksazyn-3-ylo)(2-hydroksyfenylo)metanonu |
| CN107235920A (zh) * | 2017-07-29 | 2017-10-10 | 江苏绿叶农化有限公司 | 一种嘧菌酯的合成方法 |
| CA3136908A1 (en) | 2019-04-18 | 2020-10-22 | Upl Limited | Process for preparation of azoxystrobin and intermediates thereof |
| WO2020212928A1 (en) * | 2019-04-18 | 2020-10-22 | Upl Limited | Process for the preparation of fungicidally active strobilurin compounds and intermediates thereof |
| BR112022024856A2 (pt) * | 2020-06-08 | 2022-12-27 | Upl Ltd | Processo para preparação de fluoxastrobina e seus intermediários |
| CN117548142A (zh) * | 2022-08-04 | 2024-02-13 | 北京颖泰嘉和生物科技股份有限公司 | 一种组合物及其应用 |
| CN117886774A (zh) * | 2023-12-22 | 2024-04-16 | 江苏好收成韦恩农化股份有限公司 | 氟嘧菌酯中间体的制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4136694C2 (de) | 1991-11-07 | 1996-10-10 | Inventa Ag | Stärkefaser oder Stärke-modifizierte Faser, Verfahren zu ihrer Herstellung sowie ihre Verwendung |
| DE4237882A1 (de) | 1992-11-10 | 1994-05-11 | Bayer Ag | Verfahren zur Herstellung von alpha-Fluor-beta-dicarbonylverbindungen |
| ZW8594A1 (en) | 1993-08-11 | 1994-10-12 | Bayer Ag | Substituted azadioxacycbalkenes |
| DE4408005A1 (de) | 1993-08-11 | 1995-02-16 | Bayer Ag | Substituierte Azadioxacycloalkene |
| DE19602095A1 (de) | 1996-01-22 | 1997-07-24 | Bayer Ag | Halogenpyrimidine |
| TW492962B (en) | 1996-05-30 | 2002-07-01 | Bayer Ag | Process for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl)dioxazines |
| DE19706396A1 (de) | 1996-12-09 | 1998-06-10 | Bayer Ag | Verfahren zur Herstellung von 3-(l-Hydroxiphenyl-l-alkoximinomethyl)dioxazinen |
| DE19739982A1 (de) | 1996-12-10 | 1998-06-18 | Bayer Ag | Fungizide Wirkstoffkombinationen |
| DE19710609A1 (de) | 1997-03-14 | 1998-09-17 | Bayer Ag | Substituierte Aminosalicylsäureamide |
| AU9256898A (en) | 1997-08-14 | 1999-03-08 | Bayer Aktiengesellschaft | Methoximinomethyloxadiazines used as pesticides |
| DE19744705A1 (de) * | 1997-10-10 | 1999-04-15 | Bayer Ag | Verfahren zur Herstellung gegebenenfalls substituierter Benzofuranone |
| KR100676222B1 (ko) | 1999-08-18 | 2007-01-30 | 바이엘 악티엔게젤샤프트 | 4,6-디클로로-5-플루오로피리미딘의 제조방법 |
| DE19954936A1 (de) | 1999-11-16 | 2001-05-17 | Bayer Ag | Verfahren zur Herstellung von Benzofuranonoximen |
| DE10014607A1 (de) * | 2000-03-24 | 2001-09-27 | Bayer Ag | Verfahren zur Herstellung von unsymmetrischen 4,6-Bis(aryloxy pyrimidin-Derivaten |
| TWI325302B (en) * | 2001-08-13 | 2010-06-01 | Du Pont | Benzoxazinone compounds |
| DE10226220A1 (de) | 2002-06-13 | 2003-12-24 | Bayer Cropscience Ag | Verfahren zur Herstellung von 4,6-Dichlor-5-fluorpyrimidin |
| DE10337885A1 (de) | 2003-08-18 | 2005-03-24 | Bayer Cropscience Ag | Verfahren zur Herstellung von α-Fluormalonsäuredialkylestern |
| DE102004040702B4 (de) | 2004-08-23 | 2019-03-28 | Bayer Cropscience Aktiengesellschaft | Verfahren zur Herstellung eines Dioxazin-Derivats |
| DE102004049761A1 (de) | 2004-10-12 | 2006-04-13 | Bayer Cropscience Ag | Fungizide Wirkstoffkombinationen |
-
2014
- 2014-07-03 US US14/323,413 patent/US9193698B2/en active Active
- 2014-07-03 AR ARP140102483A patent/AR100015A1/es unknown
- 2014-07-07 CA CA2917707A patent/CA2917707C/en active Active
- 2014-07-07 EP EP14822781.2A patent/EP3019495B1/en active Active
- 2014-07-07 WO PCT/US2014/045556 patent/WO2015006203A1/en not_active Ceased
- 2014-07-07 PL PL14822781T patent/PL3019495T3/pl unknown
- 2014-07-07 RU RU2016102192A patent/RU2653542C2/ru active
- 2014-07-07 CN CN201480047316.4A patent/CN105518003B/zh active Active
- 2014-07-07 BR BR122021013388-3A patent/BR122021013388B1/pt active IP Right Grant
- 2014-07-07 BR BR122021013389-1A patent/BR122021013389B1/pt active IP Right Grant
- 2014-07-07 BR BR122021013386-7A patent/BR122021013386B1/pt active IP Right Grant
- 2014-07-07 EP EP20170142.2A patent/EP3699178A1/en not_active Withdrawn
- 2014-07-07 MX MX2019000836A patent/MX368456B/es unknown
- 2014-07-07 MX MX2016000315A patent/MX364158B/es active IP Right Grant
- 2014-07-07 BR BR112016000445-0A patent/BR112016000445B1/pt active IP Right Grant
- 2014-07-07 BR BR122021013387-5A patent/BR122021013387B1/pt active IP Right Grant
- 2014-07-07 UA UAA201600290A patent/UA115093C2/uk unknown
- 2014-07-07 HU HUE14822781A patent/HUE051610T2/hu unknown
- 2014-07-07 AU AU2014287480A patent/AU2014287480B2/en active Active
-
2015
- 2015-10-23 US US14/921,657 patent/US9670171B2/en active Active
-
2016
- 2016-01-04 IL IL243455A patent/IL243455B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP3019495A1 (en) | 2016-05-18 |
| AU2014287480A1 (en) | 2016-02-04 |
| MX368456B (es) | 2019-10-03 |
| BR122021013388B1 (pt) | 2021-09-28 |
| US9670171B2 (en) | 2017-06-06 |
| US20150011753A1 (en) | 2015-01-08 |
| HUE051610T2 (hu) | 2021-03-01 |
| RU2653542C2 (ru) | 2018-05-11 |
| WO2015006203A1 (en) | 2015-01-15 |
| PL3019495T3 (pl) | 2021-01-25 |
| BR122021013387B1 (pt) | 2022-12-27 |
| EP3019495B1 (en) | 2020-06-03 |
| CN105518003A (zh) | 2016-04-20 |
| BR112016000445A2 (pt) | 2017-07-25 |
| AU2014287480B2 (en) | 2016-11-03 |
| UA115093C2 (uk) | 2017-09-11 |
| CA2917707A1 (en) | 2015-01-15 |
| BR112016000445B1 (pt) | 2021-08-17 |
| EP3699178A1 (en) | 2020-08-26 |
| BR122021013386B1 (pt) | 2023-05-16 |
| US20160237047A1 (en) | 2016-08-18 |
| CA2917707C (en) | 2018-04-10 |
| IL243455B (en) | 2018-08-30 |
| BR122021013389B1 (pt) | 2021-08-31 |
| RU2016102192A (ru) | 2017-08-11 |
| EP3019495A4 (en) | 2017-03-15 |
| US9193698B2 (en) | 2015-11-24 |
| CN105518003B (zh) | 2018-02-13 |
| MX364158B (es) | 2019-04-15 |
| AR100015A1 (es) | 2016-09-07 |
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Legal Events
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| FG | Grant or registration |